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2000

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Articles 331 - 333 of 333

Full-Text Articles in Chemistry

Chemical Oxidation Of Mtbe Under O2-Rich And O2-Limited Environments Coupled With Biological Degradation Of Oxidation Byproducts, J. Sutherland, B. Panka, Craig D. Adams, Joel Gerard Burken Jan 2000

Chemical Oxidation Of Mtbe Under O2-Rich And O2-Limited Environments Coupled With Biological Degradation Of Oxidation Byproducts, J. Sutherland, B. Panka, Craig D. Adams, Joel Gerard Burken

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The H2O2/UV Advanced Oxidation Process (AOP) Was Investigated to Determine Byproduct Formation under Different Experimental Conditions (PH, Alkalinity, and H2O2/UV Dose). a Key Factor in the Efficiency of the AOP Was the Dissolved Oxygen Concentration. Gas Chromatography/mass Spectrometry (GC/MS) Analysis Was Used to Identify Byproducts Resulting from Oxidation under Oxygen-Rich and Oxygen-Limited Conditions. Resultant Oxidation Byproducts Were Analyzed for their Susceptibility to Biological Degradation. Biodegradation Rate Constants Were Determined and Modeled for the Primary Byproducts of the Advanced Oxidation Process. Inhibition Resulting from the Presence of Multiple Byproducts in a Biological System Was Investigated as Well. Effects of Process Parameters …

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3-Hydroxykynurenine And 3-Hydroxyanthranilic Acid Generate Hydrogen Peroxide And Promote Α-Crystallin Cross Linking By Metal Ion Reduction, Lee E. Goldstein, Michael C. Leopold, Xudong Huang, Craig S. Atwood, Aleister J. Saunders, Mariana Hartshorn, James T. Lim, Et Al. Jan 2000

3-Hydroxykynurenine And 3-Hydroxyanthranilic Acid Generate Hydrogen Peroxide And Promote Α-Crystallin Cross Linking By Metal Ion Reduction, Lee E. Goldstein, Michael C. Leopold, Xudong Huang, Craig S. Atwood, Aleister J. Saunders, Mariana Hartshorn, James T. Lim, Et Al.

Chemistry Faculty Publications

The kynurenine pathway catabolite 3-hydroxykynurenine (3HK) and redox-active metals such as copper and iron are implicated in cataractogenesis. Here we investigate the reaction of kynurenine pathway catabolites with copper and iron, as well as interactions with the major lenticular structural proteins, the R-crystallins. The o-aminophenol kynurenine catabolites 3HK and 3-hydroxyanthranilic acid (3HAA) reduced Cu(II)>Fe(III) to Cu(I) and Fe(II), respectively, whereas quinolinic acid and the nonphenolic kynurenine catabolites kynurenine and anthranilic acid did not reduce either metal. Both 3HK and 3HAA generated superoxide and hydrogen peroxide in a copper-dependent manner. In addition, 3HK and 3HAA fostered copper-dependent R-crystallin cross-linking. 3HK- …

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Computerised Evaluation Of Cognitive And Motor Function, B. Kisačanin, G. C. Agarwal, J. Taber, D. (Daniel) Hier Jan 2000

Computerised Evaluation Of Cognitive And Motor Function, B. Kisačanin, G. C. Agarwal, J. Taber, D. (Daniel) Hier

Chemistry Faculty Research & Creative Works

In This Paper, We Present a Clinical Study of Computerized Tracking in the Evaluation of Cognitive and Motor Function. We Investigate its Use in the Assessment of Effectiveness of Antiepileptic Drugs (AEDs) as Well as in the Process of Following the Progress of Alzheimer's Disease (AD). to Simplify the Experiments, We Introduce Real-Time Adaptation of the Target Speed. in the Study with Epileptic Patients, Three Result Groups Are Compared: Blood Levels of AEDs, Scores on Standard Neuropsychological Tests, and Scores on Computerized Tracking and Reaction Time Tests. It is Found that the Computerized Tests Are Repeatable, Reliable and Sensitive and …

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