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Articles 1561 - 1590 of 2720
Full-Text Articles in Chemistry
Synthesis Of New Substituted 2,2-Bis-(3,5-Di-T-Butyl-4-Hydroxybenzyl)Benzocycloalkanones, Bromopropiophenones, And Their Alcohol Analogs, Jabbar Khalafy, Mehdi Rimaz, Sara Taghinejhad, Mirzagha Babazadeh
Synthesis Of New Substituted 2,2-Bis-(3,5-Di-T-Butyl-4-Hydroxybenzyl)Benzocycloalkanones, Bromopropiophenones, And Their Alcohol Analogs, Jabbar Khalafy, Mehdi Rimaz, Sara Taghinejhad, Mirzagha Babazadeh
Turkish Journal of Chemistry
A new series of substituted 2,2-bis-(3,5-di-t-butyl-4-hydroxybenzyl) benzocycloalkanones, bromopropiophenones, and their alcohol analogs were synthesized. The corresponding alcohols may act as potential allosteric modulators of GABA_B receptors.
Arsenic And Antimony Determination In Refined And Unrefined Table Salts By Means Of Hydride Generation Atomic Absorption Spectrometry--Comparison Of Sample Decomposition And Determination Methods, Nur Aksuner, Vedi̇a Nüket Ti̇rtom, Emür Henden
Arsenic And Antimony Determination In Refined And Unrefined Table Salts By Means Of Hydride Generation Atomic Absorption Spectrometry--Comparison Of Sample Decomposition And Determination Methods, Nur Aksuner, Vedi̇a Nüket Ti̇rtom, Emür Henden
Turkish Journal of Chemistry
An evaluation was made of different digestion methods for the determination of arsenic and antimony in table salt samples prior to hydride generation atomic absorption spectrometric analysis. Microwave acid digestion, classical wet digestion, dry ashing, and fusion were applied to the decomposition of salt samples and optimum conditions were investigated. Samples were decomposed by changing heating time, digestion techniques, and the amount and composition of acid, and then the concentrations of arsenic and antimony in an unrefined salt sample were measured. It is concluded that microwave acid digestion decomposes salt samples with a very short heating time and with small …
Synthesis, Characterization, And Photoluminescence Properties Of Cu(Ii), Co(Ii), Ni(Ii), And Zn(Ii) Complexes Of N-Aminopyrimidine-2-Thione, Zülbi̇ye Önal, Hüseyi̇n Zengi̇n, Mehmet Sönmez
Synthesis, Characterization, And Photoluminescence Properties Of Cu(Ii), Co(Ii), Ni(Ii), And Zn(Ii) Complexes Of N-Aminopyrimidine-2-Thione, Zülbi̇ye Önal, Hüseyi̇n Zengi̇n, Mehmet Sönmez
Turkish Journal of Chemistry
This research concentrates on the preparation, characterization, and photoluminescence properties of new Co(II), Ni(II), Cu(II), and Zn(II) complexes of N-aminopyrimidine-2-thione. The ligand and metal complexes were characterized by elemental analysis and spectroscopic studies such as IR, UV/Vis, API-ES, NMR, fluorescence, and magnetic susceptibility measurements. The ligand and the resulting metal complexes gave intense emissions (\lambda_{max} = 408 nm) upon irradiation by ultraviolet light. The photoluminescence quantum yields and long excited-state lifetimes of the ligand and its complexes were calculated. The ligand had photoluminescence quantum yields of 36% and long excited-state lifetimes of 3.40 ns. The photoluminescence intensities and quantum yields …
Structural Studies Of Complex Compounds Of 6,6'-Diacetyl-2,2'-Bipyridine Dioxime With Copper(I/Ii), Platinum(Ii), And Palladium(Ii) Metal Ions, Abdurrahman Şengül, Hakan Ağaç, Burak Çoban, Erol Eroğlu
Structural Studies Of Complex Compounds Of 6,6'-Diacetyl-2,2'-Bipyridine Dioxime With Copper(I/Ii), Platinum(Ii), And Palladium(Ii) Metal Ions, Abdurrahman Şengül, Hakan Ağaç, Burak Çoban, Erol Eroğlu
Turkish Journal of Chemistry
The tetradentate ligand 6,6'-diacetyl-2,2'-bipyridine dioxime (L) was obtained in high yield by the condensation reaction of 6,6'-diacetyl-2,2'-bipyridine with hydroxyl amine in alkaline solution. Density functional calculations and 3D modeling of the structure at the B3LYP/6-31G(d) level of theory for L revealed that the energy difference between the global trans conformer (trans-L), which possesses the C_{2h} point group, and the distorted cis conformer (cis-L) was 5.214 kcal/mol. Synthesis and characterization of the metal complexes with Cu(I), Cu(II), Pt(II), and Pd(II) metal ions were reported. L acted as a N_4-donor ligand to coordinate to the metal centers via N atoms of the …
A Study Of Behavior Of Some 5-Substituted- 4-Phenyl-1,2,4-Triazoline-3-Thiones In Sulfuric Acid Solution Using Characteristic Vector Analysis, Vesna Dimova
Turkish Journal of Chemistry
The protonation process of 1,2,4-triazoline-3-thiones (T3T) was studied in aqueous sulfuric acid using the UV method. Characteristic vector analysis (CVA) was used to reconstruct the experimentally obtained UV spectra, to overcome difficulties in calculating the protonation constants of T3T, and to separate the effect of protonation from the generalized medium effect. pK_{TH}+ values were calculated using the Hammett acidity function method, the Bunnett and Olsen method, and the excess acidity function method. The obtained values for m, \phi and m* were close to those characteristic for similar thio compounds, indicating that the protonation site in the molecule of T3T is …
A Simple And Rapid Spectrophotometric Determination Of Trace Level Simple And Rapid Spectrophotometric Determination Of Trace Level Chromium Using Bis (Salicylaldehyde) Orthophenylenediamine In Nonionic Micellar Media, Rubina Soomro, Jamaluddin Ahmed, Najma Memon
A Simple And Rapid Spectrophotometric Determination Of Trace Level Simple And Rapid Spectrophotometric Determination Of Trace Level Chromium Using Bis (Salicylaldehyde) Orthophenylenediamine In Nonionic Micellar Media, Rubina Soomro, Jamaluddin Ahmed, Najma Memon
Turkish Journal of Chemistry
Bis(salicylaldehyde)orthophenylenediamine (BSOPD) has been proposed as new analytical reagent for the direct spectrophotometric determination of chromium. It reacts with chromium(VI) in slightly acidic (0.1 -- 0.3 M H_2SO_4) micellar medium to form a yellow - orange chelate with a molar ratio 2:3. The most remarkable point of this method is that the molar absorptivities of the Cr^{VI} -- BSOPD complex formed in the presence of nonionic TritonX -- 100 surfactant are almost 10 times higher than the value observed in aqueous solution. This results in enhancing the sensitivity and selectivity of the method. The reaction is instantaneous and the maximum …
Controlled Growth Of Two-Dimensional Copper Nanoplates In Graphite Gallery, Xiaobei Bin, Jiazang Chen, Hong Cao
Controlled Growth Of Two-Dimensional Copper Nanoplates In Graphite Gallery, Xiaobei Bin, Jiazang Chen, Hong Cao
Turkish Journal of Chemistry
Copper nanoplates embedded in a graphite gallery were obtained by in situ reduction of stage 1, stage 2, and stage 3 CuCl_2-graphite intercalation compound precursors. The characterization results indicated that the morphology of the copper species was that of a 2-dimensional or quasi-2-dimensional nanoplate in the graphite gallery. Interaction between the metallic nanoplates and graphene sheet was also detected. The hexagonal graphene network restricted the crystallization orientation of the copper nanoparticles, and, at the same time, the finite space between the graphene sheets prevented the increase of the thickness. This method would provide a convenient route to synthesize or assemble …
Synthesis, Characterization, And Biological Activity Studies Of (E)-N'-((Thiophen-2-Yl)Methylene)Benzofuran-2-Carbohydrazide And Its Metal(Ii) Complexes, Madappa B. Halli, Vijayalaxmi B. Patil, Sumathi R. Bevinamarada
Synthesis, Characterization, And Biological Activity Studies Of (E)-N'-((Thiophen-2-Yl)Methylene)Benzofuran-2-Carbohydrazide And Its Metal(Ii) Complexes, Madappa B. Halli, Vijayalaxmi B. Patil, Sumathi R. Bevinamarada
Turkish Journal of Chemistry
Metal complexes of the type MLX_2, where M = Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II), and X = Cl and L = TMBC, Schiff base derived from the condensation of benzofuran-2-carbohydrazide with thiophene-2-aldehyde were synthesized. The structure of the complexes was proposed in light of analytical, IR, UV-Vis, ^1H-NMR, FAB-MS, ESR spectral data, and magnetic studies. The complexes were soluble in DMF and DMSO. The measured molar conductance values indicated that the complexes were nonelectrolytic in nature. On the basis of these studies, 6 coordinated octahedral polymeric structures were assigned to the Co(II), Ni(II), and Cu(II) complexes, and 4 …
Synthesis And Characterization Of New Symmetrical 3,6-Bis[(25,26,27- Tripropoxy-28-(3-(4-Iodophenyl) Propoxy)-P-Tert-Butyl Calix[4]Arene Ethynyl]-9h- Fluoren-9-One By Sonogashira Coupling As A Novel Precursor For Synthesis Of Quinodimethane (Qdm), Karim Akbari Dilmaghani, Fazel Nasuhi Pur
Synthesis And Characterization Of New Symmetrical 3,6-Bis[(25,26,27- Tripropoxy-28-(3-(4-Iodophenyl) Propoxy)-P-Tert-Butyl Calix[4]Arene Ethynyl]-9h- Fluoren-9-One By Sonogashira Coupling As A Novel Precursor For Synthesis Of Quinodimethane (Qdm), Karim Akbari Dilmaghani, Fazel Nasuhi Pur
Turkish Journal of Chemistry
Novel symmetrical 3,6-bis[(25,26,27-tripropoxy-28-(3-(4-iodophenyl)propoxy)-p-tert-butyl calix[4]arene ethynyl]-9H-fluoren-9-one with a cone conformation was synthesized by palladium-catalyzed coupling of (25,26,27-tripropoxy- 28-(3-(4-iodophenyl)propoxy)-p-tert-butyl calix[4]arene and 3,6-diethynyl-9H-fluoren-9-one. Its structure was confirmed by FT-IR, ^1H-NMR, and ^{13}C-NMR spectroscopy, and elemental analysis and positive ion FAB mass spectrometry.
Synthesis And Structural Analysis Of A Regular Cu-Mg-Al Hydrotalcite-Like Compound, Jiansong Wu, Yingkai Xiao, Yuping Liu, Wanbang Xu, Meifang Liang, Jian Cheng, Jianping Wan, Lingzhu Chen
Synthesis And Structural Analysis Of A Regular Cu-Mg-Al Hydrotalcite-Like Compound, Jiansong Wu, Yingkai Xiao, Yuping Liu, Wanbang Xu, Meifang Liang, Jian Cheng, Jianping Wan, Lingzhu Chen
Turkish Journal of Chemistry
A fine-quality, regular Cu-Mg-Al hydrotalcite-like compound was synthesized via the glycothermal method using CuCl_2 \cdot 2H_2O, MgCl_2 \cdot 6H_2O, AlCl_3 \cdot 6H_2O, and Na_2CO_3 as raw materials and sodium hydroxide as the precipitant. Hydrotalcite samples were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric-differential thermal analysis, and Brunauer-Emmett-Teller N_2 surface area measurements. The influence of glycol content on the characteristics of the sample was investigated. The results show that the glycol content in the system had a greater impact on regular hydrotalcite with an intercalated structure. A Cu-Mg-Al hydrotalcite-like compound with a well-defined …
Effect Of Cmc And Hpc Mixture On The Photocatalytic Activity Of Nd-Tio_2/Sio_2 Film Under Visible Light Irradiation, Parviz Aberoomand, Shahram Moradi, Susan Samadi, Mohammad Saber Tehrani, Mohammad Hadi Givianrad
Effect Of Cmc And Hpc Mixture On The Photocatalytic Activity Of Nd-Tio_2/Sio_2 Film Under Visible Light Irradiation, Parviz Aberoomand, Shahram Moradi, Susan Samadi, Mohammad Saber Tehrani, Mohammad Hadi Givianrad
Turkish Journal of Chemistry
Neodymium-titania/silica films were prepared by the sol-gel method with the addition of various amounts of hydroxy propyl cellulose (HPC) and 5.09 \times 10^{-5} g g^{-1}_{solution} of carboxy methyl cellulose (CMC) in saturated conditions. The porous Nd-TiO_2/SiO_2 was obtained after heat treatment for 2 h at 500 °C, with the surface area up to 276 m^2 g^{-1}, which was measured using the Brunauer, Emmett, and Teller (BET) method. Scanning electron microscopy (SEM) showed that the particle size of Nd-TiO_2/SiO_2 decreased and the microstructure of the film became loose in suitable conditions with the addition of CMC to HPC. Subsequently, the photocatalytic …
Synthesis And Evaluation Of The Analgesic Activity Of Some New Isoxazolo[4,5-D]Pyridazin-4(5h)-One Derivatives, Oya Ünsal Tan, Keri̇man Özadali, Özgür Yeşi̇lyurt, Hakan Kayir, İsmai̇l Tayfun Uzbay, Ayla Balkan
Synthesis And Evaluation Of The Analgesic Activity Of Some New Isoxazolo[4,5-D]Pyridazin-4(5h)-One Derivatives, Oya Ünsal Tan, Keri̇man Özadali, Özgür Yeşi̇lyurt, Hakan Kayir, İsmai̇l Tayfun Uzbay, Ayla Balkan
Turkish Journal of Chemistry
Some isoxazolo[4,5-d]pyridazin4(5H)-one derivatives were synthesized and tested for their analgesic activity. The analgesic activities of the compounds were determined by hot-plate and acetic acid writhing tests using morphine and diclofenac as references. Compounds 4a, 4f, 4g, and 4i (25 mg/kg) showed analgesic profiles similar to that of morphine (5 mg/kg).
Synthesis, Crystal Structure, And Antioxidant Properties Of Novel 1,2,4-Triazol-5-Ones Containing 3,4-Dimethoxyphenyl And 3,4-Dihydroxyphenyl Moiety, Yasemi̇n Ünver, Sevgi̇ Meydanal, Kemal Sancak, Di̇lek Ünlüer, Reşat Ustabaş, Esra Düğdü
Synthesis, Crystal Structure, And Antioxidant Properties Of Novel 1,2,4-Triazol-5-Ones Containing 3,4-Dimethoxyphenyl And 3,4-Dihydroxyphenyl Moiety, Yasemi̇n Ünver, Sevgi̇ Meydanal, Kemal Sancak, Di̇lek Ünlüer, Reşat Ustabaş, Esra Düğdü
Turkish Journal of Chemistry
A series of new 4-(3,4-dimethoxyphenethyl)-5-akyl/aryl-2H- 1,2,4-triazol-3(4H)-ones (3a-g) was obtained by the reaction of ethyl 2-(ethoxy)(alkylidene/arylidene)hydrazinecarboxylate (1) and 2-(3,4-dimethoxyphen- yl)ethanamine (2). Compounds 4a-f and 5 were synthesized from the reaction of corresponding compounds 3a-f and 3g with BBr_3, respectively. With elemental analysis, IR, ^1H-NMR, and ^{13C-NMR spectral data, 14 newly synthesized compounds were characterized. The structure of compound 3a was inferred through IR, ^1H- and ^{13}C-NMR, elemental analysis, and X-ray spectral techniques. In addition, the newly synthesized chemicals were screened for their antioxidant properties. Among the chemicals tested, 4a, 4c, 4d, 4f, and 5 exhibited the highest degree of antioxidant activity.
Bromination Of 2,3-Dihydrobenzobarrelene And Synthesis Of Its Mono- And Dibromide Derivatives: Unexpected Wagner-Meerwein Rearrangement On Silica Gel, Selçuk Eşsi̇z, Mehmet Emi̇n Şengül, Ertan Şahi̇n, Ari̇f Daştan
Bromination Of 2,3-Dihydrobenzobarrelene And Synthesis Of Its Mono- And Dibromide Derivatives: Unexpected Wagner-Meerwein Rearrangement On Silica Gel, Selçuk Eşsi̇z, Mehmet Emi̇n Şengül, Ertan Şahi̇n, Ari̇f Daştan
Turkish Journal of Chemistry
The bromination reaction of dihydrobenzobarrelene under different conditions was studied. The bromination reaction of dihydrobenzobarrelene with molecular bromine gave only a Wagner-Meerwein rearrangement product by aryl and alkyl migration. Its high-temperature bromination reaction resulted in the formation of normal addition products besides rearrangement products. The bromination reaction of the alkene with 1,2- dibromotetrachloroethane (DBTCE) gave a non-rearrangement product as the sole product. The synthesis and bromination reaction of 2-bromodihydrobenzobarrelene was also studied. An unexpected Wagner-Meerwein rearrangement was observed on silica gel during the column chromatography of isomeric tribromides. Herein, we report the results of the synthesis, and the X-ray crystal …
Antioxidant Phenolics From Lobaria Pulmonaria (L.) Hoffm. And Usnea Longissima Ach. Lichen Species, Fadi̇me Atalay, Mesut Bünyami̇ Halici, Ahmet Mavi̇, Ahmet Çakir, Fehmi̇ Odabaşoğlu, Cavi̇t Kazaz, Ali̇ Aslan, Ömer İrfan Küfrevi̇oğlu
Antioxidant Phenolics From Lobaria Pulmonaria (L.) Hoffm. And Usnea Longissima Ach. Lichen Species, Fadi̇me Atalay, Mesut Bünyami̇ Halici, Ahmet Mavi̇, Ahmet Çakir, Fehmi̇ Odabaşoğlu, Cavi̇t Kazaz, Ali̇ Aslan, Ömer İrfan Küfrevi̇oğlu
Turkish Journal of Chemistry
In this study, 1 steroidal and 8 phenolic compounds from Lobaria pulmonaria (L.) Hoffm. and Usnea longissima Ach. were isolated and their chemical structures were characterized by ^1H-NMR, ^{13}C-NMR, DEPT, ^1H-^1H COSY, HMQC, HMBC, IR, UV, and MS spectroscopic methods as stictic acid, isidiophorin, rhizonaldehyde, rhizonyl alcohol, pulmonarianin, vesuvianic acid, ergosterol peroxide, usnic acid, and diffractaic acid. Among these compounds, pulmonarianin, isolated from L. pulmonaria, was characterized for the first time as a natural compound. In addition to isolation and characterization, the lipid peroxidation inhibition and DPPH radical scavenging activities of the isolated compounds were investigated. Among these compounds, isidiophorin, …
Simultaneous Determination Of Copper And Cadmium In Environmental Water And Tea Samples By Adsorptive Stripping Voltammetry, Mohammad Bagher Gholivand, Alireza Pourhossein, Mohsen Shahlaei
Simultaneous Determination Of Copper And Cadmium In Environmental Water And Tea Samples By Adsorptive Stripping Voltammetry, Mohammad Bagher Gholivand, Alireza Pourhossein, Mohsen Shahlaei
Turkish Journal of Chemistry
A sensitive and selective method for the simultaneous determination of copper and cadmium in seawater, river water, and tea samples is described. The method is based on the adsorptive accumulation of 2,2--dithiosalicylic acid complexes of these elements onto a hanging mercury drop electrode, followed by reduction of adsorbed species by voltammetric scan using differential pulse modulation. Optimal analytical conditions were as follows: ligand concentration of 11 nM, pH of 9.5, and an adsorption potential at --300 mV versus Ag/AgCl, with an accumulation time of 60 s. The peak currents are proportional to the concentration of copper and cadmium over the …
The Sorption Of Cadmium(Ii) Ions On Mercerized Rice Husk And Activated Carbon, Mas Rosemal Hakim Mas Haris, Nor Aimi Abdul Wahab, Chong Wan Reng, Baharin Azahari, Kathiresan Sathasivam
The Sorption Of Cadmium(Ii) Ions On Mercerized Rice Husk And Activated Carbon, Mas Rosemal Hakim Mas Haris, Nor Aimi Abdul Wahab, Chong Wan Reng, Baharin Azahari, Kathiresan Sathasivam
Turkish Journal of Chemistry
This work describes the removal of Cd(II) ions in aqueous solution by unmodified and base-modified rice husk (RH) as compared to that by activated carbon (AC). Mercerization of RH was carried out by using dilute solutions (0.013 M) of NaOH, KOH, and Ca(OH)_2. The experiments were conducted in duplicate under 1-batch and 2-batch treatments. In the 1-batch treatment, a fresh 200 mg of each adsorbent was used to study the sorption of the Cd(II) ions from 100-mL solutions at an initial concentration of 5 mg L^{-1}. The adsorption percentage increased in the order of unmodified RH (80.13 \pm 0.46%) < Ca(OH)_2-modified RH (90.74 \pm 0.18%) < NaOH-modified RH (93.36 \pm 0.23%) \le KOH-modified RH (93.78 \pm 0.27%) < AC (98.4 \pm 0.18%). In the 2-batch treatment, a fresh 100 mg of each adsorbent was placed in 100-mL solutions at an initial concentration of 5 mg L^{-1} of Cd(II) ions for 30 min, and the resulting solutions were filtered. The filtrates were subjected to another fresh 100 mg of each adsorbent for an additional 30 min. The percentage removal of the metal ion using the 2-batch treatment for unmodified RH, base-modified RH, and AC was 97.71%, 98.00 \pm 1.00%, and nearly 100%, respectively.
Chemistry Of 2-Aminothiophene-3-Carboxamide And Related Compounds, Moustafa A. Gouda, Moged A. Berghot, Ghada E. Abd El-Ghani, Khaled M. Elattar, Abd El Galil M. Khalil
Chemistry Of 2-Aminothiophene-3-Carboxamide And Related Compounds, Moustafa A. Gouda, Moged A. Berghot, Ghada E. Abd El-Ghani, Khaled M. Elattar, Abd El Galil M. Khalil
Turkish Journal of Chemistry
This review describes the synthesis and reactions of 2-aminothiophene-3-carboxamides as building blocks for the syntheses of polyfunctionalized heterocyclic compounds.
Amphiphilic And Chiral Unsymmetrical Perylene Dye For Solid-State Dye-Sensitized Solar Cells, Hurmus Refiker, Hüri̇ye İci̇l
Amphiphilic And Chiral Unsymmetrical Perylene Dye For Solid-State Dye-Sensitized Solar Cells, Hurmus Refiker, Hüri̇ye İci̇l
Turkish Journal of Chemistry
A novel amphiphilic, unsymmetrically substituted N-((2S)-2-aminohexanoic acid)-N'-[(S)-1-phenylethyl]-3,4,9,10- perylenetetracarboxydiimide with 2 different chiral centers was synthesized and characterized. Chiral amphiphilicity, which can be tunable between hydrophilic and hydrophobic parts, is responsible for controlled self-assembly through intermolecular hydrogen bonding (N-H \cdots O). The product showed high thermal stability but partial solubility in common organic solvents. We observed 2 isosbestic points at 533 and 611 nm, confirming the presence of overlapped monomer and excimer emissions in the temperature range of 10-80 °C. Fluorescence quenching in m-cresol was attributed to charge-transfer interactions. Importantly, the excited state of the chiral dye can decay only by …
Power Of Inhibition Activity Screening And 3d Molecular Modeling Approaches In Hdac 8 Inhibitor Design, Gamze Bora Tatar, Tenzi̇le Deni̇z Tokluman, Kemal Yelekçi̇, Hayat Yurter
Power Of Inhibition Activity Screening And 3d Molecular Modeling Approaches In Hdac 8 Inhibitor Design, Gamze Bora Tatar, Tenzi̇le Deni̇z Tokluman, Kemal Yelekçi̇, Hayat Yurter
Turkish Journal of Chemistry
In-vitro inhibition activity screening and in-silico 3D molecular modeling approaches are important tools for design and development of specific histone deacetylase (HDAC) inhibitors. The objective of this study was to investigate the consistency between these 2 approaches. The HDAC 8 inhibition activities of 8 randomly selected different carboxylic acid derivatives were screened and in-vitro experimental results were compared with in-silico molecular modeling calculations. This study demonstrated that there is no sole gold standard technique for inhibitor design, and it was concluded that a combination of molecular modeling and activity screening assays will ensure more comprehensive and dependable results.
Facile And Convenient Synthesis Of Pyrimidine, 4h-3,1-Benzoxazin-4-One, Pyrazolo[5,1-B]Quinazoline, Pyrido[1,2-A]Quinazoline, And Chromeno[3' ,4' :4,5]Pyrido[1,2-A]Quinazoline Derivatives, Yousry A. Ammar, Samir Bondock, Abdallah G. El-Sehmi, Mohamed S.A El_Gaby, Ahmed M. Fouda, Hamdy Kh. Thabet
Facile And Convenient Synthesis Of Pyrimidine, 4h-3,1-Benzoxazin-4-One, Pyrazolo[5,1-B]Quinazoline, Pyrido[1,2-A]Quinazoline, And Chromeno[3' ,4' :4,5]Pyrido[1,2-A]Quinazoline Derivatives, Yousry A. Ammar, Samir Bondock, Abdallah G. El-Sehmi, Mohamed S.A El_Gaby, Ahmed M. Fouda, Hamdy Kh. Thabet
Turkish Journal of Chemistry
A convenient synthesis of a series of pyrimidine, 4H-3,1-benzoxazin-4-one, pyrazolo[5,1-b]quinazoline, pyrido[1,2-a]quinazoline, and chromeno[3' ,4' :4,5]pyrido[1,2-a]quinazoline derivatives, via the reactions of versatile and readily accessible methyl 2-(2-cyanoacetamido)benzoate (1) with the appropriate reagents, is described here.
Synthesis And Antimicrobial Activity Of Novel 2-(Pyridin-2-Yl)Thieno[2,3-D]Pyrimidin-4 (3h)-Ones, Nitin G. Haswani, Sanjaykumar B. Bari
Synthesis And Antimicrobial Activity Of Novel 2-(Pyridin-2-Yl)Thieno[2,3-D]Pyrimidin-4 (3h)-Ones, Nitin G. Haswani, Sanjaykumar B. Bari
Turkish Journal of Chemistry
In the present study, some new 2-(pyridin-2-yl)thieno[2,3-d] pyrimidin-4(3H)-ones derivatives (IIa-o) were synthesized. The target compounds (IIa-o) were synthesized through the acid catalyzed condensation of 2-cyano, 3-cyano, and 4-cyano-pyridines with various 2-amino-3-carbethoxythiophenes (Ia-e). All thiophene derivatives were synthesized by Gewald reaction. The structures of the newly synthesized compounds were confirmed by UV-Visible, FT-IR, ^1H-NMR, and mass spectral studies. All synthesized compounds were evaluated for their antimicrobial activity against various gram-positive and gram-negative bacterial and fungal strains. Amongst the synthesized compounds IIa, IIb, IId, IIe, and IIm were found to be active.
Determination Of Ni(Ii) With Picolinaldehyde-4-Phenyl-3-Thiosemicarbazone Used As A Chromogenic Reagent In A Nonionic Micellar System, Aamna Balouch, Muhammad Iqbal Bhanger, Farah Naz Talpur, Willie L. Hinze
Determination Of Ni(Ii) With Picolinaldehyde-4-Phenyl-3-Thiosemicarbazone Used As A Chromogenic Reagent In A Nonionic Micellar System, Aamna Balouch, Muhammad Iqbal Bhanger, Farah Naz Talpur, Willie L. Hinze
Turkish Journal of Chemistry
Spectrophotometric determination of Ni(II) was carried out using picolinaldehyde-4-phenyl-3-thiosemicarbazone (PAPT) as a complexing/chromogenic reagent. The possibility of using a micellar system was explored to enhance the degree of detection and allow a more sensitive spectrophotometric method for the determination of nickel ions. The anionic surfactant Triton X-100 greatly enhanced the molar absorptivity and limit of detection relative to that observed with bulk water or an organic solvent. The linear calibration graphs were obtained for 0.5-2.0 mg L^{-1} and 0.001-1.0 mg L^{-1} of Ni(II) in aqueous and surfactant media, respectively. Using this approach, the limit of detection for the PAPT-Ni(II) complex …
Reaction Of Cycloheptatriene Derivatives With 1,3-Diketones In The Presence Of Mn(Oac)_3, Mahi̇r Burak Südemen, Mustafa Zengi̇n, Hayri̇ye Genç, Meti̇n Balci
Reaction Of Cycloheptatriene Derivatives With 1,3-Diketones In The Presence Of Mn(Oac)_3, Mahi̇r Burak Südemen, Mustafa Zengi̇n, Hayri̇ye Genç, Meti̇n Balci
Turkish Journal of Chemistry
The reactions of some 1,3-dicarbonyl compounds with cycloheptatriene derivatives in the presence of Mn(OAc)_3 were examined. Cycloheptatriene forms mainly [2+3] and [6+3] dihydrofuran addition products derived from cycloheptatriene. However, the reaction of acetylacetone with cycloheptatriene substituted with an electron withdrawing group exclusively gave products derived from the norcaradiene structure. The formation mechanism of the products as well as the role of the substituent attached to cycloheptatriene is discussed.
Synthesis Of Some 2,3,6,8-Tetraarylimidazo[1,2-A]Pyrazine Derivatives By Using Either Reflux Or Microwave Irradiation Method, And Investigation Their Anticancer Activities, İsmai̇l Kayaği̇l, Şeref Demi̇rayak
Synthesis Of Some 2,3,6,8-Tetraarylimidazo[1,2-A]Pyrazine Derivatives By Using Either Reflux Or Microwave Irradiation Method, And Investigation Their Anticancer Activities, İsmai̇l Kayaği̇l, Şeref Demi̇rayak
Turkish Journal of Chemistry
In this study, some 2,3,6,8-tetraarylimidazo[1,2-a]pyrazine derivatives were synthesized by reacting 1-(2-aryl-2-oxoethyl)-2-aryloyl-4,5-diarylimidazoles from 2-aryloyl-4,5-diarylimidazole and 2-bromoacetophenone derivatives with ammonium acetate in acetic acid by using the method that was previously developed and repeatedly tested in our studies. Structural elucidation of the compounds was performed by IR, ^1H-NMR, and MASS spectroscopic data and elemental analysis results. Anticancer activities of selected compounds were evaluated and the noticeable activity values were reported.
Reaction Dynamics Of Br + Hd: Quantum Wave Packet On Three Potential Energy Surfaces, Qing Song, Wei-Long Quan, Tian-Jun Feng
Reaction Dynamics Of Br + Hd: Quantum Wave Packet On Three Potential Energy Surfaces, Qing Song, Wei-Long Quan, Tian-Jun Feng
Turkish Journal of Chemistry
The initial state-resolved reaction probabilities, reaction cross-sections, and rate constants of the reaction Br + HD are computed on 3 potential energy surfaces (denoted as e-LEPS, MB2, and MB3, respectively) by carrying out quantum time-dependent wave packet calculations. The results show that the reactivity of Br + HD on MB3 is much stronger than that on e-LEPS and somewhat weaker than that on MB2. Both of the vibrational and the rotational excitation of reagent HD enhance the reaction, which depends on the PESs and the strongest enhancement effects are on e-LEPS.
Azocalixarenes.7: Synthesis And Study Of The Absorption Properties Of Novel Mono-Azo Substituted Chromogenic Calix[4]Arenes, Hasaletti̇n Deli̇göz, Özlem Özen Karakuş
Azocalixarenes.7: Synthesis And Study Of The Absorption Properties Of Novel Mono-Azo Substituted Chromogenic Calix[4]Arenes, Hasaletti̇n Deli̇göz, Özlem Özen Karakuş
Turkish Journal of Chemistry
Eight new mono-azo substituted chromogenic calix[4]arenes (1-8) were synthesized by diazo-coupling reactions in which 25,26,27-tribenzoyloxy-28-hydroxy-5,11,17-tri-(tert-butyl)calix[4]arene and diazonium salts (2-, 3-, and 4-nitroaniline; 4-phenyl azoaniline; 3- and 4-chloroaniline; or 2- and 4-methylaniline) formed the corresponding mono-azo substituted derivatives in high yields. The mono-azo substituted calix[4]arenes were characterized by UV-Vis, FT-IR, and ^1H-NMR spectroscopic techniques. Elemental analysis was also carried out. In addition, the effects of varying pH levels and solvents upon the absorption ability of azocalix[4]arenes substituted with electron-donating and electron-withdrawing groups at their o-, m-, and p- positions were studied. The results proved that the absorption maxima of the prepared …
Synthesis And Antiinflammatory Activity Of Novel 2,5-Disubstituted Thiophene Derivatives, Sahar Badr
Synthesis And Antiinflammatory Activity Of Novel 2,5-Disubstituted Thiophene Derivatives, Sahar Badr
Turkish Journal of Chemistry
New series of 2,5-disubstituted thiophenes were synthesized. Thiosemicarbazones 1a-b were reacted with various reagents, such as diethyl-2-bromomalonate, ethyl-2-chloroacetoacetate, thioglycolic acid, 4-substituted phenacyl bromides, and acetic anhydride, to afford heterocyclic substituted thiophene derivatives 2a-b, 3a-b, 4a-b, 5a-b, 6a-b, and 7a-b, respectively. Moreover, cyclization of the key intermediate 1b with chloroacetic acid yielded thiazolidine 9, which on reaction with appropriate aromatic aldehydes afforded the corresponding arylidene derivatives 10a-f. Finally, reaction of N^\-arylidene cyanoacetohydrazide 11 with sulfur and phenylisothiocyanate yielded thiazoline derivative 12, which on treatment with triethylorthoformate and acetic anhydride afforded thiazolo[4,5-d]pyrimidinone derivative 13. Some of the newly synthesized compounds showed promising …
Enantioselective Complexation Of Chiral Lariat Crown Ethers And Chiral Primary Alkylammonium Perchlorates, Mehmet Zafer Köylü, Tarik Aral, Mehmet Karakaplan, Şafak Özhan Kocakaya, Hali̇l Hoşgören
Enantioselective Complexation Of Chiral Lariat Crown Ethers And Chiral Primary Alkylammonium Perchlorates, Mehmet Zafer Köylü, Tarik Aral, Mehmet Karakaplan, Şafak Özhan Kocakaya, Hali̇l Hoşgören
Turkish Journal of Chemistry
In order to investigate the enantiomeric recognition abilities toward 2 chiral alkylammonium perchlorates (AmI, AmII) by ^1H-NMR titration method in CDCl_3, 4 chiral lariat ethers 8-11 with a (p-methoxyphenoxy) methyl flexible side arm were used. The most effective enantiomeric recognition was obtained by LCEs 9 and 11 toward AmII, by K_R/K_S 6.58 and K_S/K_R 6.63, respectively. The effect of macroring size, subunit of macroring, and side arm appeared to have strong influence on the binding ability of these alkylammonium ions.
Synthesis And Characterization Of Novel Benzovesamicol Analogs, Thaer Assaad
Synthesis And Characterization Of Novel Benzovesamicol Analogs, Thaer Assaad
Turkish Journal of Chemistry
Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized by both IR and NMR spectroscopy. Compounds (\pm)-5 and (\pm)-6 showed a moderate lipophilicity compared with reference compounds IBVM and DRC140, respectively. However, the lipophilicity of DRC140 and (\pm)-9 showed very similar behaviors.