Chemistry Commons^™

Esipt-Enabled Alkyne Migration Provides Rapid Access To Benzoxazinones, Andrés G. Muñoz

Electronic Theses and Dissertations

Benozoxazinones have long been of interest to agrochemical scientists and medicinal chemists because of their widespread biological activity. These scaffolds are also of interest to synthetic chemists, who recognize the utility of benzoxazinones for accessing functionalized heterocycles. The use of efavirenz, a benzoxazinone-based reverse transcriptase inhibitor used in the treatment of HIV-1, has brought increased attention to this privileged pharmacophore. While there exist numerous strategies for synthesizing benzoxazinones, methods that do not require the use of acutely toxic and environmentally hazardous reagents are lacking. Consequently, there is a need to develop new methods for constructing this valuable scaffold. Herein, we …

Dynamics And Turnover Of Lipid And Protein Domains In Cells And Supported Bilayers, Alan Weisgerber

Electronic Theses and Dissertations

Protein and lipid clustering is an important mechanism for cell processes such as exo- and endo-cytosis and creating functional signaling complexes. It has been seen that both lipids and proteins are involved with the formation of cluster domains on cell membranes, yet little is known about the interplay between the two. In this work I began with visualizing lipid sorting to artificially induced curvature in supported lipid bilayers, with lipid tails affecting the sorting differently to curvature. These results demonstrate that lipids sort to curvature on curved, supported lipid bilayers. The sorting depends on the number of lipids in the …

Investigating Spatiotemporal Kinetics, Dynamics, And Mechanism Of Exosome Release, Anarkali Mahmood

Electronic Theses and Dissertations

Exosomes are small lipid-based vesicles that can carry biomolecules from one cell to another. While exosomes are crucial to maintain homeostasis in healthy cells, they are exploited by unhealthy cells to aid disease progression. Exosomes likely facilitate disease progression via the transfer of disease-causing biomolecules from unhealthy to healthy cells. Exosomes are generated in Multivesicular endosomes (MVEs) and are then secreted into the extracellular space to travel to other cells. Despite being a crucial step, very little is known about exosomes release mechanism and dynamics. To further our understanding of exosomes, specifically their secretion, my work has focused on investigating …

Oakland

United States Data - California

Relevant Publications

2022 Data Summary

Electron Spin Relaxation Of Nitroxide Spin Labels And Relaxation Processes, Thacien Ngendahimana

Electronic Theses and Dissertations

MTSL is the nitroxide spin label that is most commonly used in site-directed spin labeling. However, due to rotation of its gem-dimethyl groups that average anisotropic interactions, T_m becomes short above about 70 K and this makes DEER experiments difficult at these temperatures. Strategies for decreasing spin echo dephasing and electron spin lattice relaxation rates are important for design of nitroxide spin labels and molecular qubits.

In searching for labels with longer T_m, new nitroxide spin labels devoid of gemdimethyl groups or with more rigid structures were synthesized at the University of Nebraska and pulsed EPR measurements …

On-Road Vehicle Emission Measurements And Their Use In Evaluating Emission Control Effectiveness {Presentation}, Gary A. Bishop

Fuel Efficiency Automobile Test Publications

No abstract provided.

2021 West Los Angeles Data Summary, Gary Bishop

Fuel Efficiency Automobile Test Publications

Simple data summary for 2021 West Los Angeles on-road emission measurements.

2022 Oakland Ca Data Summary, Gary Bishop

Fuel Efficiency Automobile Test Publications

Simple data summary for 2022 on-road vehicle emission measurements from Oakland CA.

The Art Of Poetry And Its Place In The History Of The Coordinating Research Councils Real World Emissions Workshop {Poster}, Gary A. Bishop

Fuel Efficiency Automobile Test Publications

No abstract provided.

On-Road Nox Emissions Evaluation Of The Repair Effectiveness For Recalled Volkswagen Group Light-Duty Diesel Vehicles In The United States, Gary A. Bishop

Fuel Efficiency Automobile Test Publications

The admission by the Volkswagen Group in the fall of 2015 that they had duped the United States new vehicle emissions certification testing resulted in perhaps the most expensive violation of U.S. environmental vehicle emission regulations in its history. As part of the subsequent recall of more than 500,000 vehicles in the U.S., owners could sell their vehicles back to the companies or have them repaired. We have used a number of large on-road emission measurement data sets that were routinely collected before and after the recall to evaluate the fuel specific NO_x emissions benefit for the vehicles that …

Utah - Perry Port Of Entry 2020, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology publication.

Utah DEQ Final Report

Washington - Feat Bridge Based Train Measurements 2012, University Of Puget Sound

Non-Road Vehicle Data

Relevant Publications

Atmospheric Environment Publication (2019)

Records Of Enriched Uranium Atmospheric Deposition In Pond Sediments In Piketon, Oh, Brianna Herner, Brian Majestic, Michael Ketterer

DU Undergraduate Research Journal Archive

The enrichment of uranium, often for nuclear weapons programs and commercial nuclear reactors, produces higher concentrations of radioactive uranium 235 (²³⁵U) than what naturally occurs, which can pose a human health hazard. The most abundant naturally occurring uranium isotope is ²³⁸U, which is still radioactive, however a higher concentration of ²³⁵U skews the observed isotopic uranium distribution. The Department of Energy Portsmouth Gaseous Diffusion Plant, located near Piketon, OH, enriched uranium from 1954 to 2001 and ²³⁵U pollution has recently been detected in air and sediment samples in the surrounding community. The extent of the …

Taipei Taiwan - 1993

World Data - Asia

Relevant Publications

Environmental Science & Technology Publication (1995)

Seoul Korea - 1993

World Data - Asia

Relevant Publications

Environmental Science & Technology Publication (1995)

Leicester United Kingdom

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

Lisbon Portugal - 1994

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

Monterrey Mexico - 1995

World Data - North America

Relevant Publications

Environmental Science & Technology Publication (1997)

Final Report

Tokyo Japan - 1995

World Data - Asia

Relevant Publications

Environmental Science & Technology Publication (1995)

Malaysia - 1995

World Data - Asia

Relevant Publications

Environmental Science & Technology Publication (1995)

Hong Kong - 1993

World Data - Asia

Relevant Publications

Environmental Science & Technology Publication (1995)

Melbourne - 1992

World Data - Australia

Relevant Publications

Environmental Science & Technology Publication (1995)

Final Report

Milan Italy - 1994

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

London United Kingdom

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

Hamburg Germany - 1994

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

Edinburgh United Kingdom

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)

Toronto Canada - 1990

World Data - North America

Relevant Publications

Environmental Science & Technology Publication (1995)

Currents Publication (1991)

Mexico City Mexico

World Data - North America

Relevant Publications

Air & Waste Management Association Publication (1992)

Environmental Science & Technology Publication (1995)

Environmental Science & Technology Publication (1997)

Auckland - 2003

World Data - New Zealand

Relevant Publications

Clean Air and Environmental Quality Publication (2005)

Zurich Switzerland - 1994

World Data - Europe

Relevant Publications

Environmental Science & Technology Publication (1995)