Chemistry Commons^™

Reticular Design And Synthesis Of Metal-Organic Frameworks With Targeted Emergent Properties, David Fairchild

Electronic Theses and Dissertations, 2020-2023

The research presented in this dissertation describes the design and synthesis of substitutional-solid-solution-based multivariate metal-organic frameworks (SSS-based MTV MOFs) with functionalized organic linkers to study their emergent properties in the crystalline solid state. The synthetic versatility and tunability of organic chemistry coupled with the predictable organization of inorganic structures enables MTV MOF systems to further the fundamental understanding of structure-composition-property relationships for the targeted design of applied materials due to their ability to control the structure, composition, and property independently. To begin, a set of terphenyl linkers with varied steric and electronic properties were crystallized as a family of UiO-type …

Polymer Derived Ceramic For Lithium-Ion Storage, And Electrospun Polyelectrolyte Fiber For Heavy Metal Ions Removal, Zeyang Zhang

Electronic Theses and Dissertations, 2020-2023

This dissertation includes two major projects. The first project investigated the great potential of polymer-derived ceramics (PDCs) as lithium-ion battery anode materials with good cycling stability and large capacity. SiCNO ceramic nanoparticles were produced by pyrolysis of polysilazane nanoparticles synthesized via an oil-in-oil emulsion crosslinking. The SiCNO nanoparticles had an average particle size of around 9 nm and contained graphitic carbon, Si3N4, and SiO2 domains. The electrochemical behavior of SiCNO nanoparticles anode was investigated to evaluate the Li-ion storage performance and understand its mechanism of Li-ion storage. The lithiation of SiCNO was observed at ~0.385 V versus Li/Li+. The anode …

Analysis And Characterization Of Smokeless Powders And Smokeless Powder Residues, Emily Lennert

Electronic Theses and Dissertations, 2020-2023

The ability to associate a smokeless powder, smokeless powder residue, or organic gunshot residue (OGSR) to one another may be helpful in determining the origin of a suspected sample and aid in linking a suspect to a crime scene. In this study, smokeless powders were extracted and analyzed via gas chromatography – mass spectrometry (GC-MS) and direct analysis in real time – high resolution mass spectrometry (DART-HRMS). Subsequently, group definition was performed using hierarchical cluster analysis and principal component analysis followed by internally validated classification models. Then, smokeless powder residues were generated in-lab and extracted. Resulting residue data from each …

Investigation Of Dna Hybridization In Localized Systems In Close Proximity, Ashley M. Sewsankar

Honors Undergraduate Theses

Hybridization of two or more DNA or RNA strands is well documented for the process taking place with all strands free in solution or when one strand is immobilized on a substrate. This study contributes to the investigation of the hybridization process when two single DNA strands (ssDNA) are in close proximity. We took advantage of an X sensor in which hybridization of four DNA strands enables the formation of a DNA four-way junction (crossover or X) structure. We immobilized multiple layers of crossover structures to study its hybridization being triggered by short ssDNA coming from solution and further investigate …

Photocatalytic Hydrogen Production Over Boron Rich Solids, Emma E. Blanco

Honors Undergraduate Theses

The greenhouse emission produced from the combustion of fossil fuels, such as methane (CH_4­) and carbon dioxide (CO₂), are linked to global warming crisis because of their ability to absorb heat emitted to space by the Earth’s atmosphere. Over the last century, methane is estimated to have the Global Warming Potential (GWP) estimated to be 28-36 times larger than carbon dioxide. Although it is released in smaller quantities, methane traps nearly 90 times more heat than CO₂. While recent research efforts has focused on the capture and conversion of CO₂, these efforts …

Genomic Analysis Of Pollen Grains For Forensic Applications, Luz Kelley

Electronic Theses and Dissertations, 2020-2023

With over 300,000 plant species on the planet and more than 90% of them relying on pollen for reproduction, palynology, the study of pollen grains plays a vital role in many research fields. One of them is forensic palynology, which uses pollen as a proxy to link individuals or objects to a location or instance. It relies on the fact that (1) pollen is an ever-present feature of the environment; (2) different locations have different pollen signatures, allowing for inference related to spatial tracking; (3) plants bloom at different times, allowing for temporal inference; and (4) pollen is exceptionally durable …

Utilizing High Throughput Computing Techniques For The Predictions Of Spectroscopic Properties Of Astrophysically Relevant Molecules, Brian Ferrari

Electronic Theses and Dissertations, 2020-2023

Here, we utilize Quantum Chemistry (QC) approaches to predict the structures, vibrational frequencies, infrared intensities and Raman activities of unusual molecular species using the General Atomic and Molecular Structure System (GAMESS(US)) package. A Python-based software, AutoGAMESS, was developed to automate the workflow and take advantage of High Throughput Computing (HTC) techniques enabling the automated generation of spectroscopic data from hundreds of calculations. This approach was utilized to determine these properties for a series of carbon oxides (C2On; n = 3 to 4), anticipated to be produced during the radiation of pure carbon dioxide ices, under conditions relevant to the interstellar …

Faculty-Librarian Cooperation For Virtual Stem Based Courses: Creating Successful Learning Experiences For Undergraduate Students At Ucf, Sandy Avila, Nicole Lapeyrouse

Faculty Scholarship and Creative Works

This conference presentation was delivered at the Special Libraries Association annual virtual conference on August 12, 2021.

Session Abstract

In this session, University of Central Florida Chemistry Faculty, Dr. Nicole Lapeyrouse and Science Librarian, Sandy Avila will discuss their transition from in-person instruction to online learning during the pandemic and how their professional collaboration developed instructional resources for student success. Prior to COVID-19, a fruitful cooperative relationship was already in place, but quickly having to pivot to remote teaching and learning allowed for additional opportunities for unique experiences to be created. Those include use of open-educational e-texts, interactive online software …

13c Chemical Shift Concentration Dependence Of Phenol, Anisole, And Their Sulfur Analogs As A Probe Into Anomalous Reactivity In Electrophilic Aromatic Substitution Reactions, Braxton Lowers, Adam Reed

The Pegasus Review: UCF Undergraduate Research Journal

The ¹³C chemical shift concentration dependence of phenol, anisole, thiophenol, and thioanisole in CDCl₃ was acquired and analyzed over various concentration ranges and reported with the intention of observing the effect of hydrogen bonding on the electron density around aromatic nuclei. Of the para carbon chemical shift concentration dependences observed, phenol exhibited the most significant concentration dependence. Attempts were made to determine the functions describing concentration dependence of the ¹³C chemical shifts observed. Notably, CDCl₃ was found to exhibit relatively nonlinear concentration dependence in the same range as the compounds observed, suggesting that trace impurity and …

Analysis Of Lubricants At Trace Levels Using Infrared Spectroscopy, Tanmai Bandarupalli

Honors Undergraduate Theses

Analysis of trace evidence involved in sexual assault investigations holds considerable potential as a newer avenue of identification when bulk, larger evidence is not found or unreliable. Trace analysis of forensic materials involves common findings such as strands of hair, residues left on clothing, shards of paint or glass, etc. In recent research focused on the analysis of trace materials found as evidence in a sexual assault, there has been promise in condom and bottled lubricant classification based on their chemical profiles that can provide an associative link in an investigation. Few studies have considered the examination of lubricant evidence …

Photoluminescence Properties Of Polycyclic Aromatic Sulfur Heterocycles And Their Sorption And Desorption Onto Microplastics., Sadia Arif

Electronic Theses and Dissertations, 2020-2023

Polycyclic aromatic sulfur heterocycles (PASHs) are sulfur analogues of polycyclic aromatic hydrocarbons (PAHs) commonly found in environmental samples exposed to oil contamination. The determination of PASHs in complex samples is far more difficult than PAHs because of the sulfur atom in the heterocyclic ring, which increases the total number of possible isomeric compounds. Since their toxicological properties vary considerably from isomer to isomer, the unambiguous determination of specific isomers in environmental samples is crucial for ecotoxicological purposes and human safety. GC-MS has been the primary analytical technique for the determination of PASHs in environmental samples. Unfortunately, as the number of …

Identification And Detection Of Cosmetics Transferred During Close Personal Attacks, Kandyss Najjar

Electronic Theses and Dissertations, 2020-2023

New types of trace evidence are necessary to account for the potential lack of evidence found during criminal investigations, due to perpetrators' awareness of common types such as latent prints, hair, and DNA. During cases involving close personal contact, such as sexual assault, perpetrators may not be aware of the possible transfer of cosmetics from or onto the victim or crime scene. Therefore, this project focused on analyzing and developing characterization schemes for cosmetic components, specifically glitter and shimmer particles. Analysis of these particles was performed using various analytical techniques, such as microscopy and spectroscopy techniques, and the developed characterization …

Analysis Of Sexual Lubricants As A Form Of Trace Evidence For Sexual Assault Cases, Brooke Baumgarten

Electronic Theses and Dissertations, 2020-2023

A major gap in sexual assault casework is demonstrated when DNA is not recovered. Oftentimes, if DNA evidence is not present on the collection swabs, the sexual assault kit (SAK) is not further analyzed. Due to the "CSI effect," DNA is commonly understood as highly identifiable evidence, potentially leading to increased condom usage to eliminate or reduce DNA transfer during a sexual assault. Therefore, the analysis of condoms and sexual lubricants is pertinent. The purpose of this research is to develop analytical protocols to potentially connect unknown substances recovered in a SAK to known lubricant reference samples. Sexual lubricants were …

Applications Of The Match Model To Analyze Student Problem-Solving, Barbara Chiu

Honors Undergraduate Theses

Problem-solving has been recognized as a critical skill that students lack in the current education system, due to the use of algorithmic questions in tests that can be simply memorized and solved without conceptual understanding. Research on student problem-solving is needed to gain deeper insight into how students are approaching problems and where they lack proficiency so that instruction can help students gain a conceptual understanding of chemistry. The MAtCH (methods, analogies, theory, context, how) model was recently developed from expert explanations of their research and could be a valuable model to identify key components of student problem-solving. This project …

Classification Of Ground-Truth Fire Debris Samples Using Neural Networks, Nicholas Thurn

Electronic Theses and Dissertations, 2020-2023

Fire debris samples are currently analyzed according to ASTM E1618-19, which is the "Standard Test Method for Ignitable Liquid Residues in Extracts from Fire Debris Samples by Gas Chromatography-Mass Spectrometry." This method requires that an analyst make a visual comparison to an appropriate reference sample using the total ion and the extracted ion chromatograms. The analyst then provides an opinion about whether an ignitable liquid residue is present in the sample. The method is inherently subjective due to the visual interpretation that is needed. In order to automate this process, this work uses neural networks and a subset of the …

Polymer-Based And Functionalized 3d Microelectrode Array (Mea) Biosensors, Nilab Azim

Electronic Theses and Dissertations, 2020-2023

Microphysiological systems are three-dimensional (3D) in vitro systems that recapitulate crucial biological aspects of cell heterogeneity and native tissue architecture by mimicking complex structures that are impossible in two-dimensional (2D) cell cultures. Microelectrode arrays (MEAs) are biosensors used to spatially and temporally monitor the activity of microphysiological systems by transducing cellular signals into electronic signals to provide quantitative data on the in vitro system. Conventional MEAs are typically planar in nature, however, 3D MEAs offer several advantages such as better simulation of an in vivo cellular environment and improved signal-to-noise ratio and cell-electrode coupling. MEA fabrication utilizing traditional cleanroom methods …

Highly Reproducible Electrochemical Sensors Towards Wearable Applications And Pharmaceutical Analysis, Mohammad Rostampour Kakroudi

Electronic Theses and Dissertations, 2020-2023

Ion-selective electrodes (ISEs) are widely used to monitor ions in various applications from environmental to clinical settings and pharmaceutical analysis. ISEs are a type of potentiometric sensor that provides a versatile, cost-effective, and efficient platform towards wearable sensing applications. Among the two different platforms of ISEs (solid-contact and liquid-contact), solid-contact ISEs are superior to ISEs with internal electrolytes (liquid-contact) since they are easy to be miniaturized, can be used in any environment and their portability is facilitated. Unfortunately, mass production and commercialization of such devices is often constrained by the requirement of sensor calibration. Thus, approaches for sensor manufacturing towards …

In Situ Cultivation Of Potential Pah Degrading Bacteria From Coastal Sediment, Kyle Benkel

Honors Undergraduate Theses

Oil spills can introduce potentially carcinogenic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), into coastal environments. Bioremediation uses the natural microorganisms in the environment to remove these pollutants. Traditional studies of these organisms are limited in the types of bacteria isolated due to the limitations of traditional culturing methods. In this study, diffusion chambers were used to culture and isolate potential PAH degrading bacteria from the coastal sediment obtained from the Chandeleur Islands. The diffusion chambers trapped bacteria in agar that contained 1 ppm benzo[a]pyrene. The bacteria were isolated from the diffusion chambers, and the 16S rRNA gene was sequenced …

Detection Of A Peptide Hormone - Somatostatin - Label-Free Split-Aptameric Probes, Charles A. Dowis

Honors Undergraduate Theses

Peptide hormones are important biomolecules that transduce downstream effects such as cell proliferation, regulation, and gene expression. Their levels have been upregulated in various disorders such as cancer, yet detection methods are lacking. We designed two split aptamer-based assays for the detection of a peptide hormone – Somatostatin (SST) – with different signal readouts: fluorescent readout based on light-up aptamers and the colorimetric readout of ABTS peroxidation from a G-quadruplex. We used an already selected split-aptamer –SSTA5–for SST for our designs and we had expected the developed detection systems to exhibit detection and quantification capabilities that would hopefully allow their …

Development Of A Computer Algorithm For Generation Of Primers For Nucleic Acid Sequence Based Amplification (Nasba), Rohit Karnati

Honors Undergraduate Theses

Nucleic acid sequence based amplification (NASBA) is a primer based isothermal method of RNA/DNA amplification. Currently, primer design for NASBA has been restricted to hand creating sequences of oligonucleotides that must follow a set of rules to be compatible for the amplification process. This process of hand-creating primers is prone to error and time intensive. The detection of mutants, post amplification, also offers a benefit in point of care scenarios and the design of hybridization probes for sequences in the region of amplification is also an erroneous and time intensive process. By creating a program to design primers and hybridization …

Synthesis Of Polyacrylic Acid - Dopamine Nanoparticles As Radical Scavengers For Antioxidant Applications, Russell D. Cox

Honors Undergraduate Theses

The antioxidant activity of novel drugs has been of increasing interest in recent years. Free radicals are linked as a cause to many diseases such as atherosclerosis and cancer,1 so development of drugs that can scavenge and break down free radicals is needed. One such potential solution is using dopamine, which is water-soluble and an antioxidant. However, the tendency of antioxidant drugs reacting undesirably with proteins and other biochemical compounds is a big issue for the drugs' antioxidant potential. One solution is by encapsulating the antioxidant compound in biocompatible polymer nanoparticles. In this project, dopamine is bound to the polymer …

Chemometric Analysis Of Multidimensional Fluorescence Data Recorded From Benzo[A]Pyrene Metabolites In Shpol'skii Like Matrixes, Mohammadreza Chehelamirani

Electronic Theses and Dissertations, 2020-2023

This dissertation extends the application of Shpol'skii spectroscopy to polar metabolites in polar organic solvents. For the first-time, we reported experimental evidence on the line-narrowing effect caused by primary alcohols on the spectral features of PAH metabolites at 77 K and 4.2 K. The effect of primary alcohols (RCH2OH) on the 77 K and 4.2 K fluorescence characteristics of PAH metabolites showed the best spectral narrowing when matching the length of the alkyl group (R) of the primary alcohol to the length of the n-alkane that best fitted the dimensions of the parent PAH. The spectral narrowing and the fluorescence …

Fluoresence Spectra Study Of Sterically Strained Isomers Of C24h14 Polycyclic Aromatic (Pahs) & Characterization Of A Bio-Sourced, Fluoresent, Ratiometric Ph Indicator With Alkaline Pka, Samar Abd Alelah

Electronic Theses and Dissertations, 2020-2023

This thesis is composed to two studies, each of which relies on recent advances in time-dependent density functional theory (TD-DFT) to accurately model fluorescence spectra. The first study focuses on evaluating the fluorescence spectrum of polycyclic aromatic hydrocarbons (PAHs) having a molecular weight of 302. Three isomers are analyzed including dibenzo[a,j]fluoranthene, dibenzo[a,k]fluoranthene and dibenzo[a,l]fluoranthene. These isomers differ in the placement of one of six aromatic rings and in the amount that each molecule deviates from planarity. The TD-DFT methods are used to compute spectra in an environment that simulates solvent (n-hexane). These computed spectra are compared to vibronically resolved experimental …

Composition, Encapsulation, And Dimensionality: A Study Of The Photophysics Brought On By Synthetic Changes In Perovskite Materials, Andrew Towers

Electronic Theses and Dissertations, 2020-2023

Perovskite materials are currently being explored as a candidate for a wide variety of optoelectronic applications with a focus on active materials for solar cell and an array of lighting applications. To optimize perovskites for optoelectronic applications, a myriad synthetic and processing techniques are used to overcome limitations in the raw materials. Presently, perovskite materials have demonstrated vast improvements as candidates for solar cell and lighting applications, though the fundamental photophysical characteristics resulting from the rapid succession of synthetic developments require further investigation. Further comprehension of the basic photophysical processes being altered by synthetic and processing changes must be achieved …

Characterization Of Clear Coat And Base Coat Automotive Paint Analysis Using Dart-Hrms And Comparison Of Ftir Spectroscopy, Py-Gc-Ms, And Dart-Hrms For Clear Coat Analysis, Kaitlin Jones

Electronic Theses and Dissertations, 2020-2023

Current techniques used to analyze automotive paint samples include microscopy, fourier – transform infrared (FTIR) spectroscopy, and pyrolysis gas chromatography - mass spectrometry (Py-GC-MS). These techniques are performed in the respective order listed above. Out of the three techniques currently used in this field, the one that has the highest discriminatory power is py-GC-MS; however, this technique is time consuming and destructive toward the sample. One hundred automotive paint samples were analyzed using FTIR, Py-GC-MS and direct analysis in real time-high resolution mass spectrometry (DART-HRMS) to determine how DART-HRMS compared to Py-GC-MS in terms of discriminatory capability. DART-HRMS takes approximately …

Total Synthesis Of Natural Products From Oxidative Dearomatization, Nameer Ezzat

Electronic Theses and Dissertations, 2020-2023

The goal of our research is to prepare natural products and related core structures through oxidative dearomatization. The development of a stereoselective iron (III)-mediated intramolecular cascade dearomatization of phenol allowed access to various spirocyclohexadienones and tropons in one step using potassium ferricyanide via single electron transfer (SET). Using this oxidative dearomatization reaction, the thesis focuses on three main parts. The first part is the synthetic efforts toward total synthesis of Harringtonolide. The second part focused on the synthesis of spiro[4.5]decane, a core structure in multiple natural products. The spiro compounds were prepared from ortho hydroxyphenyl nitroalkanes using SET reaction with …

Tuning Dynamics, Sterics, And Ion Conductivities In Reticular Materials, Demetrius Vazquez-Molina

Electronic Theses and Dissertations, 2020-2023

The goal of this thesis is to synthesize libraries of organic building blocks with systematic functionalizations for tuning dynamics and steric traits in crystalline frameworks. Chapter 1 will introduce the materials being studied, their targeted applications, and a brief outline of each chapter will also be included. Chapters 2 explores the impact of mechanical processing in Covalent Organic Frameworks (COFs) from the point of view of crystallographic effects and pressure induced preferred orientation. This chapter also studies solid-state ionic conduction for Li ions in crystallographically aligned COFs studied by solid-state NMR and Electrochemical Impedance Spectroscopy (EIS), we observed fast ionic …

Optimization Of Dapoxyl Aptamer For Label-Free Bioanalysis, Jack E. Mordeson, Ryan P. Connelly, Pedro F. Madalozzo, Yulia Gerasimova

Digital Repository: Showcase of Undergraduate Research Excellence

No abstract provided.

Design, Construction, And Characterization Of A Combined Mini-Co₂/Voc Sensor And Gas Chromatograph For Field Research, Rishi Basdeo, Michael Hampton

Digital Repository: Showcase of Undergraduate Research Excellence

No abstract provided.

A Model Experiment To Investigate The Possibility Of Glyphosate Contamination In St. Kitts And Nevis, Winston Fu

Honors Undergraduate Theses

Glyphosate is a broad-spectrum herbicide that is used globally to combat the spread of weeds among crops. Not all countries around the world have been using the herbicide. For example, island countries such as Dominica and St. Kitts and Nevis do not use the herbicide on their crops. However, St. Kitts and Nevis imports food and other agricultural products from around the world, leading to the hypothesis that glyphosate is contaminating the soil through those imported products. The aim of this research project was to determine if glyphosate is present in the island country of St. Kitts and Nevis. A …