Chemistry Commons^™

The Chemistry Of Trifluorothiolacetic Acid, Patricia Diane Weeks

Dissertations and Theses

Addition reactions of perfluorothiolacetic acid (TFTAA) with organic and inorganic substrates were studied and six new compounds containing the trifluoroacetyl group have been prepared. Two types of reactions were observed, free radical and nucleophilic addition. Under the influence of ultraviolet light, TFTAA (CF₃COSH) adds to olefins to form 1:1 adducts. The CF₃COS• radical appears to be the adding species. Three new olefin adducts were prepared: CF₃COSCFHCF₂H, CF₃COSCH₂CF₂H, and CF₃COSCH₂CFH₂. In addition, this was found to be a new way to prepare CF₃COSCH₂CH₃, which had been previously prepared by another route. Physical constants, analytical data, infrared, ultraviolet, nmr and mass spectra …

Cyclization Studies Involving The Synthesis Of 5-Substituted-1-Naphthol, Clark Keelock Chow

Dissertations and Theses

The γ-o-substituted-phenylparaconic acids were prepared by a method patterned after that of Fuson. These paraconic acids were prepared in good yield. A re-investigation of the Perkin and Fittig methods of preparing γ-phenylisocrotonic acid was carried out without success.

The synthesis of γ-o-halophenylisocrotonic acids by thermal, and catalyzed decarboxylation of γ-o-halophenylparaconic acid, have been carried out in good yield. An effective catalyst, optimum temperature and reaction period of decarboxylation of the γ-o-halophenylparaconic acids have been determined. Infrared absorptions have characterized the γ-o-halophenylisocrotonic acids formed to be in the stable trans form. …

A Comparison Of The Effects Of Fluoride And Chloride Ions Upon The Activity Of Yeast Alcohol Dehydrogenase, Ellen J. Hannan

Dissertations and Theses

Very little is known about the effect of hydrofluoric acid and of the fluoride ion on enzyme systems. The purpose of this work was to determine the effect of hydrofluoric acid and of the fluoride ion on the enzyme, yeast alcohol dehydrogenase and to distinguish between the effect of the fluoride ion and of hydrofluoric acid. The rate of the enzyme reaction was followed spectrophotometrically at 340 mμ on the Cary 14 Model spectrophotometer according to the method of Racker. The data taken from the instrument recordings were plotted on two types of graphs, the Lineweaver-Burk plot and the Hanes …

Applications Of Modified Wittig Reaction To Butatriene Synthesis, John Pearson

Dissertations and Theses

The preparation of allenes by the condensation of an acyl chloride with a phosphonium ylid and subsequent elimination of an acid salt and a phosphonium oxide has been established by Bestmann and Hartung. It was felt that this process could be expanded to include the synthesis of butatrienes. Butatrienes are stabilized by aromatic substituents while aromatic substituents decrease the nucleophilicity and reactivity of the phosphonium ylids to be used in the synthesis of the butatrienes. The ylids employed were carbomethoxyphenylmethylenetriphenyl phosphorane, and a new compound, carbethoxyphenylmethylenetriphenyl phosphorane, both of which failed to form alkylated condensation products. Both ylids were prepared …

Bacterial Degradation Of Methyl Dehydroabietate, Burl C. Carter

Dissertations and Theses

Bacteria (Arthrobacter sp.), isolated from lodgepole pine (Pinus contortus), are capable of utilizing methyl dehydroabietate as the sole source of carbon. Degradation products of methyl dehydroabietate have been obtained by manually extracting the cell-free supernatant solution of a liquid growth medium with methylene chloride. Gas chromatography (G. L. C.) was used for separation of the neutral products. The acid products were converted to their methyl esters diazomethane and then separated by gas chromatography. Structures have been proposed for two G. L. C. fractions (V, II) on the basis of infrared (I.R.) and mass spectral (M. S.) data. …

The Identification Of The Inorganic Components In The Calcareous Corpuscles From Mesocestoides Corti, Larry M. Kegley

Dissertations and Theses

The inorganic components in calcareous corpuscles from Mesocestoides corti have been identified by use of powder x-ray diffraction and emission spectroscopy. Difference methods were compared for the isolation of the calcareous corpuscles from the residual tissue of the Mesocestoides corti. Previously reported and newly developed methods for the isolation are discussed.

Analyses by powder x-ray diffraction for in vivo samples which had been heated at various temperatures ranging from room temperature to 1000°C are reported.

The qualitative emission spectrographic analyses for in vivo and in vitro corpuscles are reported for normal systems and systems designed to study the ion …

The Ion-Exchange Chromatographic Separation Of The Components Of The Product Mixture Resulting From Reaction Of Trans-Dichlorobis (Ethylenediamine) Cobalt (Iii) Chloride With Thiocyanate Ion, William Trew Jordan

Dissertations and Theses

The object of the research was to study, by means of ion-exchange chromatography, the product mixture resulting from reaction of trans-[Co(en)₂Cl₂]Cl and SCN^-. Cis-and trans-[Co(en)₂(NCS)Cl]Cl had previously been obtained as products of this reaction. However, the possibility of the presence of other products consistent with the nature of the reactants could not be dismissed. These include the dichlora, dithiocyanato, and aqua complexes.

The constituents of the solution resulting from the reaction were separated on a column of Dowex 50W-X8 resin by elution with hydrochloric acid. The eluted fractions were evaporated at room …