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Articles 181 - 210 of 288
Full-Text Articles in Chemistry
Enantioselective Synthesis Of Dual Serotonergic Azanoradamantane Sc-52491, Daniel Becker, Robert K. Husa, Alan E. Moormann, Clara I. Villamil
Enantioselective Synthesis Of Dual Serotonergic Azanoradamantane Sc-52491, Daniel Becker, Robert K. Husa, Alan E. Moormann, Clara I. Villamil
Chemistry: Faculty Publications and Other Works
A racemic synthesis of azanoradamantane (±)-3 was accomplished via Yamamoto's MAD-catalyzed Diels-Alder protocol. Subsequently, a scalable asymmetric synthesis of azanoradamantane benzamide SC-52491 was carried out employing Helmchen's asymmetric Diels-Alder methodology to construct all four contiguous asymmetric centers with the correct relative stereochemistry and in 99.3% e.e.
Biophysical Studies Of The Spectrin Sequence Motif, Denise M. Lusitani
Biophysical Studies Of The Spectrin Sequence Motif, Denise M. Lusitani
Dissertations
No abstract provided.
Mechanistic Studies Of Cation Photogeneration, Mary Frances Clifton
Mechanistic Studies Of Cation Photogeneration, Mary Frances Clifton
Dissertations
No abstract provided.
Novel Synthetic Route To 5-Substituted Indoles, Helen Y. Chen
Novel Synthetic Route To 5-Substituted Indoles, Helen Y. Chen
Master's Theses
No abstract provided.
Serotonin 5-Ht4 Agonist Activity Of A Series Of Meso-Azanoradamantane Benzamides, Daniel Becker, Roger Nosal, Clara I. Villamil, Gary Gullikson
Serotonin 5-Ht4 Agonist Activity Of A Series Of Meso-Azanoradamantane Benzamides, Daniel Becker, Roger Nosal, Clara I. Villamil, Gary Gullikson
Chemistry: Faculty Publications and Other Works
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4agonist in the series, with an EC50 of 217 nM.
Synthetic Strategies For The Construction Of Enantiomeric Azanoradamantanes, Daniel Becker, Roger Nosal, Daniel L. Zabrowski, Daniel Flynn
Synthetic Strategies For The Construction Of Enantiomeric Azanoradamantanes, Daniel Becker, Roger Nosal, Daniel L. Zabrowski, Daniel Flynn
Chemistry: Faculty Publications and Other Works
The amino azanoradamantane hexahydro-2,5b-methano-IH-3aS,3aa,6aa-cyclopenta-[clpyrrole-4a-amine 1and the corresponding enantiomer ent-1 have been prepared along with benzamide derivatives SC-52491and SC-52490, respectively, which are of pharmaceutical interest. The key meso-azabicyclo[3.3.0] intermediate 3 was prepared via three separate routes: a [3+2] cycloaddition route, a radical cyclization/ionic cyclization route, and a reductive Pauson-Khand route.
The Computational Study Of "Model" Pollutants In Clay Montmorillonite, Sung-Ho Park
The Computational Study Of "Model" Pollutants In Clay Montmorillonite, Sung-Ho Park
Dissertations
No abstract provided.
Syntheses Of Monometallic And Bimetallic Pd(Ii) Catalysts Supported On Polymer Surface And Their Applications In Organic Syntheses, Qin Jian Yu
Master's Theses
No abstract provided.
Novel Palladium (Ii) Catalysts For Asymmetric Synthesis, Arab El-Qisairi
Novel Palladium (Ii) Catalysts For Asymmetric Synthesis, Arab El-Qisairi
Dissertations
No abstract provided.
Multinuclear Magnetic Resonance Studies Of Anion Binding To Copper, Zinc-Superoxide Dismutase, And Of Lithium Transport And Binding In Cultured Neuroblastoma Cells, Cherian Zachariah
Multinuclear Magnetic Resonance Studies Of Anion Binding To Copper, Zinc-Superoxide Dismutase, And Of Lithium Transport And Binding In Cultured Neuroblastoma Cells, Cherian Zachariah
Dissertations
No abstract provided.
Development Of Crosslinking Reagents, And Intra- And Intermolecular Multi-Linking Hemoglobin Molecules As Potential Blood Substitutes, Yaguo Zheng
Dissertations
No abstract provided.
A Multinuclear Magnetic Resonance Study Of Cesium And Chloride Distribution In Human Erythrocyte Suspensions, Wanrong Lin
A Multinuclear Magnetic Resonance Study Of Cesium And Chloride Distribution In Human Erythrocyte Suspensions, Wanrong Lin
Dissertations
No abstract provided.
Asymmetric Synthesis By Palladium (Ii) Catalysis: Chirality Transfer And New A Symmetric Catalytic System, Othman Hamed
Asymmetric Synthesis By Palladium (Ii) Catalysis: Chirality Transfer And New A Symmetric Catalytic System, Othman Hamed
Dissertations
No abstract provided.
Oxidative Reactions In Normal And Sickle Hemoglobin-Lipid Mixtures Under Various Conditions, Merita Nirmali Dias
Oxidative Reactions In Normal And Sickle Hemoglobin-Lipid Mixtures Under Various Conditions, Merita Nirmali Dias
Dissertations
No abstract provided.
Competition Between Li+ And Mg2+ For Human Rbcmembrane Phospholipids And Guanine Nucleotide Binding Proteins, Chandra Srinivasan
Competition Between Li+ And Mg2+ For Human Rbcmembrane Phospholipids And Guanine Nucleotide Binding Proteins, Chandra Srinivasan
Dissertations
No abstract provided.
Ionic Interaction Studies Of Bovine Copper, Zinc-Superoxide Dismutase, Hanan A. Hasan
Ionic Interaction Studies Of Bovine Copper, Zinc-Superoxide Dismutase, Hanan A. Hasan
Dissertations
No abstract provided.
Ph And Osmolality Effects On Lipid-Enhanced Sickle And Normahemoglobin Oxidation, Sharron Kay Jenkins
Ph And Osmolality Effects On Lipid-Enhanced Sickle And Normahemoglobin Oxidation, Sharron Kay Jenkins
Dissertations
No abstract provided.
Molecular Dynamics Of The Hammerhead Ribozyme, Vasant T. Gandhi
Molecular Dynamics Of The Hammerhead Ribozyme, Vasant T. Gandhi
Master's Theses
No abstract provided.
Molecular Dynamics Of Crosslinked And Normal Hemoglobins, Liang Zhao
Molecular Dynamics Of Crosslinked And Normal Hemoglobins, Liang Zhao
Master's Theses
No abstract provided.
The Application Of Matrix Assisted Laser Desorption Ionization Time Of-Flight Mass Spectrometry (Maldi Tof Ms) For Dna Adducts And Cross-Linked Hemoglobin Analysis, Xiaomei Gu
Master's Theses
No abstract provided.
Effects Of Perinatal Exposure To Cocaine On Sexually Differentiated Gonadotropin Regulation In Rats, Jihun M. Lee
Effects Of Perinatal Exposure To Cocaine On Sexually Differentiated Gonadotropin Regulation In Rats, Jihun M. Lee
Master's Theses
No abstract provided.
One-Pot Preparation Of 1,3-Dihydro-1- (Trifluoromethyl)Isobenzofuran-1-Ol Derivatives From 1,2-Dibromobenzene, Daniel Becker, Hui Li, Daniel L. Flynn
One-Pot Preparation Of 1,3-Dihydro-1- (Trifluoromethyl)Isobenzofuran-1-Ol Derivatives From 1,2-Dibromobenzene, Daniel Becker, Hui Li, Daniel L. Flynn
Chemistry: Faculty Publications and Other Works
A one-pot method for the preparation of 1,3-dihydro-1-(trifluoromethyl)isobenzofuran-1-ol derivatives 5from 1,2-dibromobenzene is described
Preparation Of Trifluoromethyl Lactol Derivatives Via Base Initiated Cyclobutanol Ring Opening To A Laterally Lithiated Trifluoromethyl Ketone, Daniel Becker, Daniel L. Flynn
Preparation Of Trifluoromethyl Lactol Derivatives Via Base Initiated Cyclobutanol Ring Opening To A Laterally Lithiated Trifluoromethyl Ketone, Daniel Becker, Daniel L. Flynn
Chemistry: Faculty Publications and Other Works
Benzocyclobutenone derivatives 4 are converted to the corresponding trifluoromethylcyclobutanols 5 by treatment with trifluoromethyltrimethylsilane in the presence of tetra-n-butylammonium fluoride. These trifluoromethylcyclobutanol derivatives are then treated with LiTMP in the presence of aromatic aldehydes to afford trifluoromethyllactols 6 via a laterally-lithiated trifluoromethylketone intermediate.
Photophysics And Photochemistry Of Carbocations, Maria R. Valentino
Photophysics And Photochemistry Of Carbocations, Maria R. Valentino
Dissertations
No abstract provided.
Electrochemical Cleavage Of Phenylsulfones, Joseph E. Lohr
Electrochemical Cleavage Of Phenylsulfones, Joseph E. Lohr
Master's Theses
No abstract provided.
The Development, Molecular Characterization And Application Of A Model Stratum Corneum Lipid System, Rita M. Hatfield
The Development, Molecular Characterization And Application Of A Model Stratum Corneum Lipid System, Rita M. Hatfield
Dissertations
No abstract provided.
Molecular Studies Of Human Erythrocyte Spectrin: Head To-Head Interactions, Nasser Qtaishat
Molecular Studies Of Human Erythrocyte Spectrin: Head To-Head Interactions, Nasser Qtaishat
Dissertations
No abstract provided.
Development Of A Unique Photothermal Interferometer, Michael Henry
Development Of A Unique Photothermal Interferometer, Michael Henry
Dissertations
No abstract provided.
The Synthesis Of Azure B Derivatives: Potential Pro-Drugs For Photodynamic Therapy, Carla M. Edwards
The Synthesis Of Azure B Derivatives: Potential Pro-Drugs For Photodynamic Therapy, Carla M. Edwards
Dissertations
No abstract provided.
Na+-H+ Exchange And Na+-Li+ Exchange In Human Erythrocytes: An Nmr Investigation, Yuling Chi
Na+-H+ Exchange And Na+-Li+ Exchange In Human Erythrocytes: An Nmr Investigation, Yuling Chi
Dissertations
No abstract provided.