Partial Differential Equations Commons^™

Optimal Control Frameworks For A Class Of Epidemiological And Oncological Models, Asma Ali H Alghamdi

Mathematics Dissertations - Archive

In this thesis, we employ optimal control frameworks in two distinct contexts: Human immunodeficiency virus (HIV) and esophageal cancer. For HIV, we introduce a comprehensive data-driven nonlinear optimization framework designed for personalized therapies. This framework utilizes a deterministic in-host nonlinear ordinary differential equation (ODE) model and formulates two optimization problems using individual patient data. The first problem focuses on estimating patient-specific parameters through constrained optimization, while the second problem determines optimal combination therapies to reduce viral load to undetectable levels. Several numerical experiments suggest that our framework can provide a robust and effective optimal dosages with lower toxicity levels to …

Exploring Sigmoidal Bounded Confidence Models With Mean Field Methods, Tian Dong

HMC Senior Theses

Mathematicians use models of opinion dynamics to describe how opinions in a group of people change over time, which can yield insight into mechanisms behind phenomena like polarization and consensus. In these models, mathematicians represent the community as a graph, where nodes represent agents and edges represent possible interactions. Opinion updates are modeled with a system of differential equations (ODEs). Our work focuses on the sigmoidal bounded confidence model (SBCM), where agents update their opinion toward a weighted average of their neighbors' opinions by weighting similar opinions more heavily. Using tools developed in physics (mean-field theory), we derive a continuity …

Integrable Evolution Equations, Ramesh C. Sharma

Mathematics Dissertations - Archive

Integrable evolution equations are certain nonlinear partial differential equations or semidiscrete nonlinear difference equations that are used to model wave propagation in various media. The goal of this thesis is to present the derivation of integrable evolution equations in a way accessible to nonexperts in the field of integrable systems and to illustrate those derivations by various explicit examples. In the case of nonlinear partial differential equations, both the spacial variable x and temporal variable t are continuous independent variables. In the case of semidiscrete nonlinear difference equations, the spacial variable n is a discrete independent variable and the temporal …

Hamiltonian Models For The Propagation Of Long Gravity Waves, Higher-Order Kdv-Type Equations And Integrability, Rossen Ivanov

Book chapter/book

A single incompressible, inviscid, irrotational fluid medium bounded above by a free surface is considered. The Hamiltonian of the system is expressed in terms of the so-called Dirichlet-Neumann operators. The equations for the surface waves are presented in Hamiltonian form. Specific scaling of the variables is selected which leads to a KdV approximation with higher order nonlinearities and dispersion (higher-order KdV-type equation, or HKdV). The HKdV is related to the known integrable PDEs with an explicit nonlinear and nonlocal transformation.

Analysis And Detection Of Cyber Attacks In Multi Vehicle Systems Using Macroscopic Models, Abhishek Kashyap

Mechanical and Aerospace Engineering Dissertations - Archive

The study of potential cyber-attacks in different domains is an active area of research. Given that systems are becoming more and more interconnected, cyber physical systems that operate infrastructure and/or plants can make these assets more vulnerable and open to different attack vectors. The primary focus of this research is the modeling, analysis and detection of cyber-attacks on platoons of autonomous cars and swarms of UAVs. In this work, we consider scenarios wherein an attacker may hack into a subset of vehicles in a multi-vehicle system and make subtle modifications in their parameters. Due to the interconnected nature of the …

Uniform Regularity Estimates For The Stokes System In Perforated Domains, Jamison R. Wallace

Theses and Dissertations--Mathematics

We consider the Stokes equations in an unbounded domain $\omega_{\epsilon,\eta}$ perforated by small obstacles, where $\epsilon$ represents the minimal distance between obstacles and $\eta$ is the ratio between the obstacle size and $\epsilon$. We are able to obtain uniform $W^{1,q}$ estimates for solutions to the Stokes equations in such domains with bounding constants depending explicitly on $\epsilon$ and $\eta$.

Advancements In Elliptic Mesh Redistribution And Automated Overset Grid Generation For Computational Fluid Dynamics, Chase Ashby

Theses and Dissertations--Mathematics

Automated and robust structured curvilinear overset grid generation remains a significant challenge for the application of computational fluid dynamics. This thesis intro- duces a specialized anisotropic Mach cone aligned adaptation algorithm for low-boom simulations and an automated procedure for generating structured curvilinear overset grids for immersed boundary simulations. Results demonstrate that anisotropic mesh adaptation can reduce computational resource usage by over 50% while maintaining sonic boom prediction accuracy across the entire sonic boom domain compared to user-constructed Mach cone aligned grids. The proposed immersed overset grid gen- eration procedure eliminates the need for complex surface generation algorithms, producing grids suitable …

Investigation Of Space Charge Effects On Co2 Electrocatalytic Reduction On Gd-Doped Ceria Via Scanning Kelvin Probe And Model-Based Bayesian Analysis, Alejandro Mejia

Graduate Theses, Dissertations, and Problem Reports (ETD)

In studying novel energy conversion and storage systems, such as high-temperature electrolysis, numerous underlying fundamental physical processes remain unclear or inadequately understood. Among these, the modeling and comprehension of surface reaction mechanisms, coupled with the intricate effects of space‑charge interfaces, remains an unclear and challenging area of research.

The work of this dissertation involves the development of a 2D finite element analysis model, leveraging the robust MOOSE framework from INL. This model, featuring inhomogeneous defect thermodynamics for near-surface chemistry, formulated through Poisson‑Cahn variational theory, has been exploited for studying the electrocatalytic reduction of CO₂ on gadolinia doped ceria. The …

A Class Of Game-Theoretic And Fokker-Planck Optimal Control Frameworks In Colon And Esophageal Cancer, Mesfer Alajmi Phd

Mathematics Dissertations - Archive

In this dissertation, we first present a new stochastic framework for parameter estimation and uncertainty quantification in colon cancer-induced immune responses. A stochastic process that captures the system's inherent randomness determines the dynamics of colon cancer. The stochastic framework is based on the Fokker-Planck equation, which represents the evolution of the probability density function corresponding to the stochastic process. We formulate an optimization problem that takes individual patient data with randomness present and solves it to obtain the unknown parameters corresponding to the individual tumor characteristics. Furthermore, we perform a sensitivity analysis of the optimal parameter set to identify the …

Echolocation On Manifolds, Kerong Wang

Honors Theses

We consider the question asked by Wyman and Xi [WX23]: ``Can you hear your location on a manifold?” In other words, can you locate a unique point x on a manifold, up to symmetry, if you know the Laplacian eigenvalues and eigenfunctions of the manifold? In [WX23], Wyman and Xi showed that echolocation holds on one- and two-dimensional rectangles with Dirichlet boundary conditions using the pointwise Weyl counting function. They also showed echolocation holds on ellipsoids using Gaussian curvature.

In this thesis, we provide full details for Wyman and Xi's proof for one- and two-dimensional rectangles and we show that …

Symmetry Analysis Of The Canonical Connection On Lie Groups:Co-Dimension Two Abelian Nilradical With Abelian And Non Abelian Complement, Nouf Alrubea Almutiben

Theses and Dissertations

We consider the symmetry algebra of the geodesic equations of the canonical
connection on a Lie groups. We mainly consider the solvable indecomposable four,
five and six-dimensional Lie algebras with co-dimension two abelian nilradical, that
have an abelian and not abelian complement. In this particular case, we have only
one algebra in dimension four namely; A4,12 , and three algebras in dimension five
namely; A5,33, A5,34, and A5,35 In dimension six, based on the list of Lie algebras in
Turkowski’s list, there are nineteen such algebras namely; A6,1- A6,19 that have an
abelian complement, and there are eight algebras that …

Discontinuous Galerkin Methods For Compressible Miscible Displacements And Applications In Reservoir Simulation, Yue Kang

Dissertations, Master's Theses and Master's Reports

This dissertation contains research on discontinuous Galerkin (DG) methods applied to the system of compressible miscible displacements, which is widely adopted to model surfactant flooding in enhanced oil recovery (EOR) techniques. In most scenarios, DG methods can effectively simulate problems in miscible displacements.
However, if the problem setting is complex, the oscillations in the numerical results can be detrimental, with severe overshoots leading to nonphysical numerical approximations. The first way to address this issue is to apply the bound-preserving
technique. Therefore, we adopt a bound-preserving Discontinuous Galerkin method
with a Second-order Implicit Pressure Explicit Concentration (SIPEC) time marching
method to …

Mathematical Modeling Of Coupled Heat And Mass Transfer In Metal-Hydride Hydrogen Storage Systems, Muhammad Hasnain

College of Graduate Studies: Theses & Dissertations

As a promising clean energy carrier hydrogen has recently gained significant interest, but its efficient and safe storage is a major challenge. Compared to the gaseous state and liquid state, metal hydrides (MH) offer a potentially more effective storage approach for hydrogen. However, the main challenge in this approach is the low thermal conductivity of the MH bed that leads to low heat transfer and ultimately to higher charging and discharging times. The purpose of this work is to develop an in-house comprehensive heat and mass transfer model for hydrogen sorption in MH reactors to simulate the dynamic behavior of …

Numerical Modeling Of Thermal Runaway In Lithium-Ion Batteries Using Decomposition Kinetics And Inter-Cell Contact Resistance, Shehzad Khan

College of Graduate Studies: Theses & Dissertations

Lithium-ion batteries (LIBs) are central in numerous high-demand applications due to their high energy density and prolonged cycle life. Despite these advantages, their susceptibility to thermal runaway (TR) poses a significant safety risk, with the potential for catastrophic failures. This study focuses on the thermal behavior of prismatic lithium-ion cells, using a finite volume-based partial differential equation (PDE) solver developed in MATLAB and JULIA to model TR behavior. This solver accurately simulates transient behaviors, convection, diffusion, and source terms across various coordinate systems. By engaging in a series of increasing complex case studies, this research aims to identify the critical …

Long-Wave Modeling Of Viscous Film Dynamics Inside A Tube With Time-Dependent Radius, Robert E. Hicks

Theses and Dissertations

Lung fluid dynamics is a well studied topic and relevant in the field of research surrounding patients with Chronic Obstructive Pulmonary Disease (COPD) and cystic fibrosis. However, the literature on the mathematical description of the net pulmonary fluid transport in the case of constricting and expanding airways is scarce. In this paper we aim to address how breathing contributes to airways clearance in patients with pulmonary diseases such as COPD and CF in which cilia do not function properly. We begin with the flow of a fluid-filled tube with rigid walls of fixed radius and the effects of gravity being …

Simulation Of Wave Propagation In Granular Particles Using A Discrete Element Model, Syed Tahmid Hussan

College of Graduate Studies: Theses & Dissertations

The understanding of Bender Element mechanism and utilization of Particle Flow Code (PFC) to simulate the seismic wave behavior is important to test the dynamic behavior of soil particles. Both discrete and finite element methods can be used to simulate wave behavior. However, Discrete Element Method (DEM) is mostly suitable, as the micro scaled soil particle cannot be fully considered as continuous specimen like a piece of rod or aluminum. Recently DEM has been widely used to study mechanical properties of soils at particle level considering the particles as balls. This study represents a comparative analysis of Voigt and Best …

Last Passage Time And Excursion Theory For Solvable Diffusions With Applications In Mathematical Finance, Yaode Sui

Theses and Dissertations (Comprehensive)

In this dissertation, we investigate the properties of last passage times and excursion theory in one-dimensional solvable diffusions, emphasizing their applications in financial modeling, particularly in option pricing. We derive closed-form formulas for the marginal distribution of last passage times and their joint distribution with process values, including the maximum and minimum of the process value. The focus is on time-homogeneous diffusions with various boundaries and imposed killing. Employing spectral expansion theory, we derive explicit formulas for distributions of last passage times in common processes such as Drifted Brownian Motion (BM), Squared Bessel (SQB), Ornstein-Uhlenbeck (OU), and Cox-Ingersoll-Ross (CIR) models. …

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …

Linear Topological Space, Vi Nguyen

UNF Graduate Theses and Dissertations

This thesis begins with an introduction to linear and topological spaces and then defines linear topological spaces. It studies key properties such as neighborhoods, convexity, reflexivity, and weak and weak* topologies. Finally, it concludes with solving non-linear partial differential equations.