Ordinary Differential Equations and Applied Dynamics Commons^™

Statistical Mobility Of Aggregated Microswimmers, Yonatan Ashenafi

Biology and Medicine Through Mathematics Conference

No abstract provided.

Impacts Of Hematodinium Infection In A Seasonal Population Model Of The Chesapeake Bay Blue Crab, Gwendolyn R. Sargent, Romuald Lipcius, Leah Shaw, Junping Shi, Jeffrey D. Shields

Biology and Medicine Through Mathematics Conference

No abstract provided.

Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematically Modeling Stoichiometric Drivers Of Nitrogen Fixation, Rebecca Everett, Corday Selden, Mohamed Hatha Abdulla, Jabir Thajudeen, James Powell, Edwin Cruz-Rivera, Luca Schenone, Renn Schipper, Megan Berberich, Halvor Halvorson, Robinson Fulweiler, Amy Marcarelli, Thad Scott

Biology and Medicine Through Mathematics Conference

No abstract provided.

Analytical And Numerical Analysis Of The Sirs Model, Catherine Nguyen

Departmental Honors & Graduate Capstone Projects

Mathematical models in epidemiology describe how diseases affect and spread within a population. By understanding the trends of a disease, more effective public health policies can be made. In this paper, the Susceptible-Infected-Recovered-Susceptible (SIRS) Model was examined analytically and numerically to compare with the data for Coronavirus Disease 2019 (COVID-19). Since the SIRS model is a complex model, analytical techniques were used to solve simplified versions of the SIRS model in order to understand general trends that occur. Then by Euler's Method, the Runge-Kutta Method, and the Predictor-Corrector Method, computational approximations were obtained to solve and plot the SIRS model. …

Proof-Of-Concept For Converging Beam Small Animal Irradiator, Benjamin Insley

Dissertations and Theses (Open Access)

The Monte Carlo particle simulator TOPAS, the multiphysics solver COMSOL., and

several analytical radiation transport methods were employed to perform an in-depth proof-ofconcept

for a high dose rate, high precision converging beam small animal irradiation platform.

In the first aim of this work, a novel carbon nanotube-based compact X-ray tube optimized for

high output and high directionality was designed and characterized. In the second aim, an

optimization algorithm was developed to customize a collimator geometry for this unique Xray

source to simultaneously maximize the irradiator’s intensity and precision. Then, a full

converging beam irradiator apparatus was fit with a multitude …

Deterministic Global 3d Fractal Cloud Model For Synthetic Scene Generation, Aaron M. Schinder, Shannon R. Young, Bryan J. Steward, Michael L. Dexter, Andrew Kondrath, Stephen Hinton, Ricardo Davila

Faculty Publications

This paper describes the creation of a fast, deterministic, 3D fractal cloud renderer for the AFIT Sensor and Scene Emulation Tool (ASSET). The renderer generates 3D clouds by ray marching through a volume and sampling the level-set of a fractal function. The fractal function is distorted by a displacement map, which is generated using horizontal wind data from a Global Forecast System (GFS) weather file. The vertical windspeed and relative humidity are used to mask the creation of clouds to match realistic large-scale weather patterns over the Earth. Small-scale detail is provided by the fractal functions which are tuned to …

Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad

Dissertations

The high prevalence of dental caries among children and adolescents, especially those from lower socio-economic backgrounds, is a significant nationwide health concern. Early prevention, such as dental sealants and fluoride varnish (FV), is essential, but access to this care remains limited and disparate. In this research, a national dataset is utilized to assess sealants' reach and effectiveness in preventing tooth decay, particularly focusing on 2nd molars that emerge during early adolescence, a current gap in the knowledge base. FV is recommended to be delivered during medical well-child visits to children who are not seeing a dentist. Challenges and facilitators in …

Modeling An Infection Outbreak With Quarantine: The Sibkr Model, Mikenna Dew, Amanda Langosch, Theadora Baker-Wallerstein

Rose-Hulman Undergraduate Mathematics Journal

Influenza is a respiratory infection that places a substantial burden in the world population each year. In this project, we study and interpret a data set from a flu outbreak in a British boarding school in 1978 with mathematical modeling. First, we propose a generalization of the SIR model based on the quarantine measure in place and establish the long-time behavior of the model. By analyzing the model mathematically, we determine the analytic formulas of the basic reproduction number, the long-time limit of solutions, and the maximum number of infection population. Moreover, we estimate the parameters of the model based …

Stability Of Predator-Prey Model For Worm Attack In Wireless Sensor Networks, Rajeev Kishore, Padam Singh

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we propose a predator-prey mathematical model for analyzing the dynamical behaviors of the system. This system is an epidemic model, and it is capable of ascertaining the worm's spreading at the initial stage and improving the security of wireless sensor networks. We investigate different fixed points and examine the stability of the projected model.

Existence And Uniqueness Of Solutions Of Sobolev Type Second Order Integrodifferential Equation, Kamalendra Kumar, Manish Nath Tripathi

Applications and Applied Mathematics: An International Journal (AAM)

The primary concern of this article is to establish the existence, uniqueness and continuous dependence on initial data of mild solutions of second order mixed integrodifferential equations of Sobolev type in Banach spaces. For this objective, we employ the idea of strongly continuous cosine family of operators, the modified version of Banach theorem and Grownwall’s inequality. The model is demonstrated to elucidate the abstract conclusion.

Infusing Quantitative Reasoning Skills Into A Differential Equation Class In An Urban Public Community College, Tanvir Prince

Numeracy

This research centers on implementing Quantitative Reasoning (QR) within a differential equations course at an urban public community college. As a participant in the Numeracy Infusion for College Educators (NICE) faculty development program, I sought to integrate QR skills into my curriculum. Students in the course were introduced to QR goals using real-world data sets, particularly those related to population growth, which aim to enhance their understanding, sharpen their problem-solving abilities, and cultivate a positive perspective on the real-world relevance of mathematics. Preliminary findings indicate varied levels of QR skill development among students. These results underscore the potential benefits of …

A Tale Of Two Viruses: Why Smallpox Was Eradicated And Polio Persists, Katherine G. Mcgough, Erin N. Bodine

Spora: A Journal of Biomathematics

The smallpox and poliomyelitis (polio) viruses were, at a time, one of the largest threats to global public health killing millions until global eradication campaigns were put into effect. Vaccination led to the eradication of smallpox and the elimination of polio for most of the world. However, polio continues to persist at endemic levels in Pakistan and Afghanistan. We developed ODE models of smallpox and polio to explore differences in transmission dynamics and determine if the underlying biology has made poliomyelitis more difficult to eradicate. Our model analysis shows there are multiple factors which should allow polio to have a …

A Coupled Model Of Population, Poaching, And Economic Dynamics To Assess Rhino Conservation Through Legal Trade, Henry Doyle, Kylie Champagne, Ditto Rajpal, Grace Seebeck, David J. Gerberry

Spora: A Journal of Biomathematics

Rhinoceros populations in Africa are in peril largely due to the high value of their horns and the poaching that ensues. The strategy of legalizing the international trade of rhino horn is receiving increased support among both the people and government officials in Africa. Many in the international conservation community remain opposed to the idea. The legalization strategy is straightforward in theory: legalizing the trade of rhino horn will introduce a large quantity of horn to the market, the increased supply will lead to lower prices for rhino horn, and lower prices will reduce the overall poaching pressure these animals …

Odes And Mandatory Voting, Christoph Borgers, Natasa Dragovic, Anna Haensch, Arkadz Kirshtein, Lilla Orr

CODEE Journal

This paper presents mathematics relevant to the question whether voting should be mandatory. Assuming a static distribution of voters’ political beliefs, we model how politicians might adjust their positions to raise their share of the vote. Various scenarios can be explored using our app at https: //centrism.streamlit.app/. Abstentions are found to have great impact on the dynamics of candidates, and in particular to introduce the possibility of discontinuous jumps in optimal candidate positions. This is an unusual application of ODEs. We hope that it might help engage some students who may find it harder to connect with the more customary …

Modeling Aircraft Takeoffs, Catherine Cavagnaro

CODEE Journal

Real-world applications can demonstrate how mathematical models describe and provide insight into familiar physical systems. In this paper, we apply techniques from a first-semester differential equations course that shed light on a problem from aviation. In particular, we construct several differential equations that model the distance that an aircraft requires to become airborne. A popular thumb rule that pilots have used for decades appears to emanate from one of these models. We will see that this rule does not follow from a representative model and suggest a better method of ensuring safety during takeoff. Aircraft safety is definitely a matter …

Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum

CODEE Journal

Common mechanistic models include Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models. These models in their basic forms have generally failed to capture the nature of the COVID-19 pandemic's multiple waves and do not take into account public policies such as social distancing, mask mandates, and the ``Stay-at-Home'' orders implemented in early 2020. While the Susceptible-Vaccinated-Infected-Recovered-Deceased (SVIRD) model only adds two more compartments to the SIR model, the inclusion of time-dependent parameters allows for the model to better capture the first two waves of the COVID-19 pandemic when surveillance testing was common practice for a large portion of the population. We find …

Optimal Control Frameworks For A Class Of Epidemiological And Oncological Models, Asma Ali H Alghamdi

Mathematics Dissertations - Archive

In this thesis, we employ optimal control frameworks in two distinct contexts: Human immunodeficiency virus (HIV) and esophageal cancer. For HIV, we introduce a comprehensive data-driven nonlinear optimization framework designed for personalized therapies. This framework utilizes a deterministic in-host nonlinear ordinary differential equation (ODE) model and formulates two optimization problems using individual patient data. The first problem focuses on estimating patient-specific parameters through constrained optimization, while the second problem determines optimal combination therapies to reduce viral load to undetectable levels. Several numerical experiments suggest that our framework can provide a robust and effective optimal dosages with lower toxicity levels to …

Integrable Evolution Equations, Ramesh C. Sharma

Mathematics Dissertations - Archive

Integrable evolution equations are certain nonlinear partial differential equations or semidiscrete nonlinear difference equations that are used to model wave propagation in various media. The goal of this thesis is to present the derivation of integrable evolution equations in a way accessible to nonexperts in the field of integrable systems and to illustrate those derivations by various explicit examples. In the case of nonlinear partial differential equations, both the spacial variable x and temporal variable t are continuous independent variables. In the case of semidiscrete nonlinear difference equations, the spacial variable n is a discrete independent variable and the temporal …

Using A Degree-Based Network Model To Understand And Control Traffic Jams In The Atlanta Metropolitan Area, Ian Salamone-Lent, Theresa Washington, Asma Azizi

The Kennesaw Journal of Undergraduate Research

Traffic congestion is an enduring problem for major metropolitan areas, such as Atlanta, GA. Our goal is to understand the nature of traffic congestion patterns in the highway system of Cobb County in Atlanta, GA. We created a road network representative of the Cobb County highway system and then superimposed a degree-based SIR model to simulate traffic congestion on that network. The model’s parameters, propagation and dissipation rates, were estimated using empirical traffic data, which are vehicles’ speed time series and speed limit of each road in the network. We then conducted a local sensitivity analysis of the model’s key …

A New Mechanistic Model Of Brain Metabolism With Optimal Parametrization, Alice Lubbe

Mathematics Dissertations - Archive

Models of glucose metabolism in the brain often focus on chemical exchanges and reactions that occur as part of the tricarboxylic acid cycle (TCA cycle). Experiments involving nuclear magnetic resonance (NMR) spectroscopy to detect and measure carbon-labeled isotopomers of metabolites such as glutamate in vivo inform kinetic, mechanistic models used to study metabolic pathways. In the present work, a new model with two compartments, astrocytic and neuronal, is developed using known biochemical processes and fit to experimental data coming from fully labeled glucose infusions. A gradient descent method is introduced and employed to obtain optimal flux parameter values involved in …

A Class Of Game-Theoretic And Fokker-Planck Optimal Control Frameworks In Colon And Esophageal Cancer, Mesfer Alajmi Phd

Mathematics Dissertations - Archive

In this dissertation, we first present a new stochastic framework for parameter estimation and uncertainty quantification in colon cancer-induced immune responses. A stochastic process that captures the system's inherent randomness determines the dynamics of colon cancer. The stochastic framework is based on the Fokker-Planck equation, which represents the evolution of the probability density function corresponding to the stochastic process. We formulate an optimization problem that takes individual patient data with randomness present and solves it to obtain the unknown parameters corresponding to the individual tumor characteristics. Furthermore, we perform a sensitivity analysis of the optimal parameter set to identify the …

A Novel Scheme Based On Bessel Operational Matrices For Solving A Class Of Nonlinear Systems Of Differential Equations, Atallah El-Shenawy, Mohamed El-Gamel, Muhammad E. Anany

Mansoura Engineering Journal

The system of ordinary differential equations arises in many natural phenomena, especially in the field of disease spread. In this paper, a perfect spectral technique is introduced to solve systems of nonlinear differential equations. The technique enhanced the Bessel collocation technique by converting the series notation of unknown variables and their derivatives to matrix relations. The Newton algorithm is developed to solve the resulting nonlinear system of algebraic equations. The effectiveness of the scheme is proved by the convergence analysis and error bound as demonstrated in Theorem 1. The scheme of solution is tested to clarify the efficiency and the …

Estimating Modeling Parameters For Covid-19 Spread On Campus, Aviel S. Crigger

Honors Undergraduate Theses

Understanding the true burden of community transmission of communicable diseases like COVID-19 is crucial for effective public health response. Clinical cases, while important, only represent a fraction of the actual disease prevalence within a population. In this thesis, we investigate methods to estimate parameters that link clinical cases to the true disease prevalence using a modified compartmental model known as SICR (Susceptible, Infected, Cases, Recovered). We employ Bayesian inference and ensemble Markov chain Monte Carlo (MCMC) simulations to analyze clinical case data provided by the University of Central Florida Health Center from 2020 to 2022. Our goal is to estimate …

Characterizing Probabilities Of Outbreaks Of Dengue In Central Argentina Using A Temperature-Dependent Stochastic Model, Morgan H. Jackson, Elizabet L. Estallo, Cheng Ly, Michael A. Robert

Graduate Research Posters

Dengue virus (DENV) causes over 390 million infections and around 40,000 deaths worldwide each year. DENV is primarily transmitted by the mosquito Aedes aegypti, and both the life cycle of these mosquitoes and dengue transmission are significantly impacted by temperature. In the temperate region of Central Argentina, where dengue outbreaks first began in 2009, outbreaks of dengue can only occur due to new introductions of DENV from other regions. Due to the relationships between temperature and dengue, the risk of outbreak changes throughout the year.

We develop a stochastic model including temperature-dependent mosquito life history traits and transmission-related parameters. …

Mathematical Modeling And Analysis Of Inflammation And Tissue Repair: Lung Inflammation And Wound Healing In Corals Under Stress, Quintessa Hay

Theses and Dissertations

A variety of insults, including tissue injury and/or exposure to pathogen, elicit an immune response in many organisms. An improperly regulated immune response can result in deleterious effects to the organism. Here we present models for lung injury in young and old mice and models for wound healing in coral reefs.

It is well known that the immune response becomes less effective in older individuals. This is of particular interest in pulmonary insults such as ventilator induced lung injury (VILI) or lung infection. We extended a mathematical model for the inflammatory response to VILI and used experimental data to select …

Mathematical Analysis Of Eukaryotic Pericentromere, Puranjan Ghimire

Theses and Dissertations

The centromere is crucial for chromosomal stability and their proper segregation during cell division in eukaryotes. Surrounding the centromere are pericentromeres, made of repetitive DNA elements called pericentromeric repeats, varying from 10 in fission yeast to thousands in humans. These repeats form densely packed heterochromatin, where genes are usually silenced. The silencing mechanism across different pericentromeric repeats remains unclear.

Despite variations in sequence and length, pericentromeric repeats are conserved across eukaryotes, indicating their functional importance. This dissertation presents mathematical models to quantify gene silencing in fission yeast and humans. In fission yeast, my model predicts that silencing occurs only with …

Mathematical Modeling Of Phage-Bacteria Population Dynamics, John Lawrence D. Palacios

Theses and Dissertations

Bacteriophages are viruses that infect and replicate within bacteria. Lytic phages cause the bacterial cell to burst, killing the bacteria. These types of phages can be used to treat patients with antibiotic-resistant bacterial infections. As a step in developing successful treatment protocols, we aim to understand the population dynamics of phages and bacteria using an in vitro model. We model the dynamics using the Campbell model, which consists of a delay differential equation (DDE), as a base model. We extended the model by including the emergence of phage resistance. We then compared the DDE model with a parallel ordinary differential …

Advanced Techniques In Time Series Forecasting: From Deterministic Models To Deep Learning, Xue Bai

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation discusses three instances of temporal prediction, applied to population dynamics and deep learning.

In population modeling, dynamic processes are frequently represented by systems of differential equations, allowing for the analysis of various phenomena. The first application explores modeling cloned hematopoiesis in chronic myeloid leukemia (CML) via a nonlinear system of differential equations. By tracking the evolution of different cell compartments, including cycling and quiescent stem cells, progenitor cells, differentiated cells, and terminally differentiated cells, the model captures the transition from normal hematopoiesis to the chronic and accelerated-acute phases of CML. Three distinct non-zero steady states are identified, representing …

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …