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Articles 151 - 180 of 227

Full-Text Articles in Ordinary Differential Equations and Applied Dynamics

Stability Of Delayed Virus Infection Model With A General Incidence Rate And Adaptive Immune Response, Zhimin Chen, Xiuxiang Liu, Zhongzhong Xie Dec 2018

Stability Of Delayed Virus Infection Model With A General Incidence Rate And Adaptive Immune Response, Zhimin Chen, Xiuxiang Liu, Zhongzhong Xie

Applications and Applied Mathematics: An International Journal (AAM)

We present the dynamical behaviors of a virus infection model with general infection rate, immune responses and two intracellular delays which describe the interactions of the HIV virus, target cells, CTL cells and antibodies within host. Three factors are incorporated in this model: (1) the intrinsic growth rate of uninfected cells, (2) a nonlinear incidence rate function considering both virus-tocell infection and cell-to-cell transmission, and (3) a nonlinear productivity and removal function. By the method of Lyapunov functionals and LaSalle’s invariance principle, we show that the global dynamics of the model is determined by the reproductive numbers for viral infection …


Parameter Estimation And Optimal Control Of The Dynamics Of Transmission Of Tuberculosis With Application To Cameroon, A. Temgoua, Y. Malong, J. Mbang, S. Bowong Dec 2018

Parameter Estimation And Optimal Control Of The Dynamics Of Transmission Of Tuberculosis With Application To Cameroon, A. Temgoua, Y. Malong, J. Mbang, S. Bowong

Applications and Applied Mathematics: An International Journal (AAM)

This paper deals with the problem of parameter estimation and optimal control of a tuberculosis (TB) model with seasonal fluctuations. We first present a uncontrolled TB model with seasonal fluctuations. We present the theoretical analysis of the uncontrolled TB model without seasonal fluctuations. After, we propose a numerical study to estimate the unknown parameters of the TB model with seasonal fluctuations according to demographic and epidemiological data from Cameroon. Simulation results are in good accordance with the seasonal variation of the new active reported cases of TB in Cameroon. Using this TB model with seasonality, the tuberculosis control is formulated …


A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch Oct 2018

A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Transmission Of Wolbachia In Mosquitoes For Controlling Mosquito-Borne Diseases, Zhuolin Qu Oct 2018

Modeling The Transmission Of Wolbachia In Mosquitoes For Controlling Mosquito-Borne Diseases, Zhuolin Qu

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Calcium Signaling In The Sperm Head, Julie Simons, Lisa Fauci Oct 2018

Calcium Signaling In The Sperm Head, Julie Simons, Lisa Fauci

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Combinatorial Geometry Of Threshold-Linear Networks, Christopher Langdon Oct 2018

Combinatorial Geometry Of Threshold-Linear Networks, Christopher Langdon

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Dynamics Of A Stoichiometric Producer-Grazer System With Seasonal Effects On Light Level, Lale Asik Oct 2018

Dynamics Of A Stoichiometric Producer-Grazer System With Seasonal Effects On Light Level, Lale Asik

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Implications From Two Prostate Cancer Models For Intermittent Therapy, Tin Phan Oct 2018

Implications From Two Prostate Cancer Models For Intermittent Therapy, Tin Phan

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer Oct 2018

Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Household Model Of German Cockroach Infestations And Their Effect On Symptoms Of Atopic Asthma, Karen Funderburk Oct 2018

A Household Model Of German Cockroach Infestations And Their Effect On Symptoms Of Atopic Asthma, Karen Funderburk

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Parameter Sensitivity For In Vitro Anthrax Studies, Yareley Gonzalez, Maria Macias-Bedolla, Megan O. Powell Sep 2018

Parameter Sensitivity For In Vitro Anthrax Studies, Yareley Gonzalez, Maria Macias-Bedolla, Megan O. Powell

Spora: A Journal of Biomathematics

Studies done on interactions between spores and macrophages done in vitro show inconsistent results based on experimental protocol and inhibit meaningful extrapolation to in vivo. In this study, we perform a sensitivity analysis of a model representing in vitro studies of interactions between anthrax spores and macrophages to help address the effects of these inconsistencies. We perform both local and global analyses using Latin hypercube sampling and partial rank correlation coefficients. Our analysis indicates the amount of intracellular bacteria over time is most sensitive to the killing of intracellular bacteria by the macrophages and replication of the bacteria inside …


Generation Of Nonlinear-Differential-Equations System From A Model Of Boolean Relationships In Arabidopsis Salt Stress Network, Renee Dale May 2018

Generation Of Nonlinear-Differential-Equations System From A Model Of Boolean Relationships In Arabidopsis Salt Stress Network, Renee Dale

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Hcv Interactions With P53: Implications For Carcinogenesis, Harsh Jain May 2018

Modeling Hcv Interactions With P53: Implications For Carcinogenesis, Harsh Jain

Biology and Medicine Through Mathematics Conference

No abstract provided.


Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea May 2018

Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea

Biology and Medicine Through Mathematics Conference

No abstract provided.


Disruption Of Synchronous Behavior In Pancreatic Islets Via Hub Cells, Janita Patwardhan May 2018

Disruption Of Synchronous Behavior In Pancreatic Islets Via Hub Cells, Janita Patwardhan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong May 2018

Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong

Biology and Medicine Through Mathematics Conference

No abstract provided.


Staged Hiv Transmission And Treatment In A Dynamic Model With Concurrency, Katharine Gurski, Kathleen Hoffman May 2018

Staged Hiv Transmission And Treatment In A Dynamic Model With Concurrency, Katharine Gurski, Kathleen Hoffman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Disappearance Of The Neanderthals Using Concepts Of Population Dynamics And Ecology, Michael F. Roberts, Stephen E. Bricher Jan 2018

Modeling The Disappearance Of The Neanderthals Using Concepts Of Population Dynamics And Ecology, Michael F. Roberts, Stephen E. Bricher

Faculty Publications

Current hypotheses regarding the disappearance of Neanderthals (NEA) in Europe fall into two main categories: climate change, and competition. Here we review current research and existing mathematical models that deal with this question, and we propose an approach that incorporates and permits the investigation of the current hypotheses. We have developed a set of differential equations that model population dynamics of anatomically modern humans (AMH) and NEA, their ecological relations to prey species, and their mutual interactions. The model allows investigators to explore each of the two main categories or combinations of both, as well as various forms of competition …


Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla Nov 2017

Stochastic Analysis Of A Mammalian Circadian Clock Model: Small Protein Number Effects, David W. Morgens, Blerta Shtylla

Spora: A Journal of Biomathematics

The circadian clock, responsible for coordinating organism function with daily and seasonal changes in the day-night cycle, is controlled by a complex protein network that constitutes a robust biochemical oscillator. Deterministic ordinary differential equation models have been used extensively to model the behavior of these central clocks. However, due to the small number of proteins involved in the circadian oscillations, mathematical models that track stochastic variations in the numbers of clock proteins may reveal more complex and biologically relevant behaviors. In this paper, we compare the response of a robust yet detailed deterministic model for the mammalian circadian clock with …


Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo Nov 2017

Age-Structured And Vaccination Models Of Devil Facial Tumor Disease, Christopher D. Bruno, Timothy Comar, Megan O. Powell, Adjo Tameklo

Spora: A Journal of Biomathematics

Tasmanian devil populations have been devastated by devil facial tumor disease (DFTD) since its first appearance in 1996. The average lifespan of a devil has decreased from six years to three years. We present an age-structured model to represent how the disease has affected the age and breeding structures of the population. We show that with the recent increase in the breeding of juvenile devils, the overall devil population will increase but not nearly to pre-DFTD levels. The basic reproductive number may be increased with the influx of young breeding devils. In addition, our model shows that the release of …


The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers Oct 2017

The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu Oct 2017

Modeling Cdc42 Oscillation In Fission Yeast, Bin Xu

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


One Tick, Two Tick, Two Pathogens, Oh No! Am I Sick?, Caleb L. Adams Oct 2017

One Tick, Two Tick, Two Pathogens, Oh No! Am I Sick?, Caleb L. Adams

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed Oct 2017

A Model Of Dengue Transmission With Wolbachia-Free And Wolbachia-Infected Mosquitoes, Iftikhar Ahmed

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Influence Of El Niño On Parasite Transmission In Sand Crab Populations And Seabird Abundance Along The California Coast, James Peirce, Olcay Akman, Abou Seck Oct 2017

Modeling The Influence Of El Niño On Parasite Transmission In Sand Crab Populations And Seabird Abundance Along The California Coast, James Peirce, Olcay Akman, Abou Seck

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore Oct 2017

The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis Oct 2017

Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Parts Of The Whole: Why I Teach This Subject This Way, Dorothy Wallace Jul 2017

Parts Of The Whole: Why I Teach This Subject This Way, Dorothy Wallace

Numeracy

The importance of mathematics to biology is illustrated by search data from Google Scholar. I argue that a pedagogical approach based on student research projects is likely to improve retention and foster critical thinking about mathematical modeling, as well as reinforce quantitative reasoning and the appreciation of calculus as a tool. The usual features of a course (e.g., the instructor, assessment, text, etc.) are shown to have very different purposes in a research-based course.


Modeling Hiv Dynamics Following 3bnc117 Antibody Infusion, Samantha Erwin May 2017

Modeling Hiv Dynamics Following 3bnc117 Antibody Infusion, Samantha Erwin

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of E-Antigen In Hepatitiv B Virus Infection, Mirjam Sarah Kadelka May 2017

The Role Of E-Antigen In Hepatitiv B Virus Infection, Mirjam Sarah Kadelka

Biology and Medicine Through Mathematics Conference

No abstract provided.