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Disease Modeling

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Articles 31 - 58 of 58

Full-Text Articles in Ordinary Differential Equations and Applied Dynamics

Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D. May 2020

Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D.

Undergraduate Research and Scholarship Symposium

Starting in the 1990s, physicians across the United States have increasingly prescribed opioid pain relievers, which has given rise to the current opioid epidemic. As a result, there has been a drastic increase in the number of overdose fatalities. In 2017, the number of opioid overdose deaths peaked and the U.S. declared the crisis as a public health emergency. One state that has contributed significantly to this epidemic is Pennsylvania, which ranks first for the greatest number of overdose deaths and third for the highest death rate. In fact, Allegheny County has witnessed an overdose death rate that is three …


A Study Of Cholera Transmission, Urmi Ghosh-Dastidar Apr 2020

A Study Of Cholera Transmission, Urmi Ghosh-Dastidar

Open Educational Resources

A recent cholera outbreak in Haiti brought public attention to this disease. Cholera, a diarrheal disease, is caused by an intestinal bacterium, and if not addressed in a timely manner may become fatal. During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools. Students will learn to develop a differential equation model based on practical scenarios, analyze the model using mathematics as well as numerical simulation, and finally describe the results in words that are understandable by the people who are not specialists in this …


Evaluation Of Age- And Risk-Based Mass Drug Administration Policies To Control Soil-Transmitted Helminths: A Mathematical Modeling Study Of Ghana, Mugdha Thakur Oct 2019

Evaluation Of Age- And Risk-Based Mass Drug Administration Policies To Control Soil-Transmitted Helminths: A Mathematical Modeling Study Of Ghana, Mugdha Thakur

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren Oct 2019

Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku May 2019

Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch Oct 2018

A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer Oct 2018

Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Household Model Of German Cockroach Infestations And Their Effect On Symptoms Of Atopic Asthma, Karen Funderburk Oct 2018

A Household Model Of German Cockroach Infestations And Their Effect On Symptoms Of Atopic Asthma, Karen Funderburk

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Hcv Interactions With P53: Implications For Carcinogenesis, Harsh Jain May 2018

Modeling Hcv Interactions With P53: Implications For Carcinogenesis, Harsh Jain

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong May 2018

Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Dynamics Of An Epidemiological Model For Human Papillomavirus With Partial Vaccination In A Heterogeneous Population, Stefano Chiaradonna Oct 2017

The Dynamics Of An Epidemiological Model For Human Papillomavirus With Partial Vaccination In A Heterogeneous Population, Stefano Chiaradonna

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Dftd Age Structure And Vaccination Modeling, Christopher D. Bruno Oct 2017

Dftd Age Structure And Vaccination Modeling, Christopher D. Bruno

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers Oct 2017

The Kinetics Of Type I Interferons During Influenza A Virus Infection, Margaret A. Myers

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore Oct 2017

The Role Of Intermittent Preventive Treatment For Malaria In Saving Lives And Promoting Drug Resistance, Carrie Manore

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis Oct 2017

Mathematical Medicine: Modeling Disease And Treatment, Lisette Depillis

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Kinetics Of Type I Interferons During Influenza Virus Infection, Margaret A. Myers May 2017

The Kinetics Of Type I Interferons During Influenza Virus Infection, Margaret A. Myers

Biology and Medicine Through Mathematics Conference

No abstract provided.


Control Policies And Sensitivity Analysis In A Cutaneous Leishmaniasis Model: A Case Study In Cusco Region, Peru., Rocio M. Caja-Rivera, Ignacio Barradas May 2017

Control Policies And Sensitivity Analysis In A Cutaneous Leishmaniasis Model: A Case Study In Cusco Region, Peru., Rocio M. Caja-Rivera, Ignacio Barradas

Biology and Medicine Through Mathematics Conference

No abstract provided.


Influence Of Preventive Measures To Eradicate The Spread Of The Zika Arbovirus, Pradyuta Padmanabhan, Padmanabhan Seshaiyer Oct 2016

Influence Of Preventive Measures To Eradicate The Spread Of The Zika Arbovirus, Pradyuta Padmanabhan, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Impact Of Devil Facial Tumor Disease On The Tasmanian Devil Age Structure, Christopher Bruno, Vashni Vasquez Oct 2016

Impact Of Devil Facial Tumor Disease On The Tasmanian Devil Age Structure, Christopher Bruno, Vashni Vasquez

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Kinetics Of Type 1 Interferons During Influenza Virus Infection, Margaret A. Myers Oct 2016

The Kinetics Of Type 1 Interferons During Influenza Virus Infection, Margaret A. Myers

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Optimal Control Of Vaccination Rate In An Epidemiological Model Of Clostridium Difficile Transmission, Brittany Stephenson Oct 2016

Optimal Control Of Vaccination Rate In An Epidemiological Model Of Clostridium Difficile Transmission, Brittany Stephenson

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Bi-Stable Switch In Virus Dynamics Can Explain The Differences In Disease Outcome Following Siv Infections In Rhesus Macaques, Stanca Ciupe, Christopher Miller, Jonathan Forde May 2016

A Bi-Stable Switch In Virus Dynamics Can Explain The Differences In Disease Outcome Following Siv Infections In Rhesus Macaques, Stanca Ciupe, Christopher Miller, Jonathan Forde

Biology and Medicine Through Mathematics Conference

No abstract provided.


Using Mathematical Modeling To Unmask The Concealed Nature Of Long Qt-3 Syndrome, Steven Poelzing, Amara Greer-Short, Seth H. Weinberg May 2016

Using Mathematical Modeling To Unmask The Concealed Nature Of Long Qt-3 Syndrome, Steven Poelzing, Amara Greer-Short, Seth H. Weinberg

Biology and Medicine Through Mathematics Conference

No abstract provided.


Optimal Insecticide-Treated Bed-Net Coverage And Malaria Treatment In A Malaria-Hiv Co-Infection Model, Eric Numfor May 2016

Optimal Insecticide-Treated Bed-Net Coverage And Malaria Treatment In A Malaria-Hiv Co-Infection Model, Eric Numfor

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Model Of The Spread Of Dengue Fever Incorporating Mobility, Kelly A. Reagan May 2016

A Mathematical Model Of The Spread Of Dengue Fever Incorporating Mobility, Kelly A. Reagan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Global Dynamics Of A Model Of Joint Hormone Treatment With Dendritic Cell Vaccine For Prostate Cancer, Erica M. Rutter, Yang Kuang May 2016

Global Dynamics Of A Model Of Joint Hormone Treatment With Dendritic Cell Vaccine For Prostate Cancer, Erica M. Rutter, Yang Kuang

Biology and Medicine Through Mathematics Conference

No abstract provided.


Can Including Time Delay In Epidemic Models Significantly Improve Predictions Concerning Intervention Strategies?, Adrienna N. Bingham, Leah Shaw May 2016

Can Including Time Delay In Epidemic Models Significantly Improve Predictions Concerning Intervention Strategies?, Adrienna N. Bingham, Leah Shaw

Biology and Medicine Through Mathematics Conference

No abstract provided.


Optimal Therapy Regimens For Treatment-Resistant Mutations Of Hiv, Weiqing Gu, Helen Moore Jan 2006

Optimal Therapy Regimens For Treatment-Resistant Mutations Of Hiv, Weiqing Gu, Helen Moore

All HMC Faculty Publications and Research

In this paper, we use control theory to determine optimal treatment regimens for HIV patients, taking into account treatment-resistant mutations of the virus. We perform optimal control analysis on a model developed previously for the dynamics of HIV with strains of various resistance to treatment (Moore and Gu, 2005). This model incorporates three types of resistance to treatments: strains that are not responsive to protease inhibitors, strains not responsive to reverse transcriptase inhibitors, and strains not responsive to either of these treatments. We solve for the optimal treatment regimens analytically and numerically. We find parameter regimes for which optimal dosing …