Numerical Analysis and Computation Commons^™

Modelling And Optimal Control For Nonlinear Multistage Dynamical System Of Microbial Fed-Batch Culture, Chongyang Liu, Zhaohua Gong, Enmin Feng, Hongchao Yin

Chongyang Liu

In this paper, we propose a new controlled multistage system to formulate the fed-batch culture process of glycerol bio-dissimilation to 1,3-propanediol (1,3-PD) by regarding the feeding rate of glycerol as a control function. Compared with the previous systems, this system doesn’t take the feeding process as an impulsive form, but a time-continuous process, which is much closer to the actual culture process. Some properties of the above dynamical system are then proved. To maximize the concentration of 1,3-PD at the terminal time, we develop an optimal control model subject to our proposed controlled multistage system and continuous state inequality constraints. …