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Applied Mathematics Commons

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2023

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Articles 181 - 210 of 376

Full-Text Articles in Applied Mathematics

When Are The Natural Embeddings Of Classical Invariant Rings Pure?, Melvin Hochster, Jack Jeffries, Vaibhav Pandey, Anurag K. Singh Jul 2023

When Are The Natural Embeddings Of Classical Invariant Rings Pure?, Melvin Hochster, Jack Jeffries, Vaibhav Pandey, Anurag K. Singh

Department of Mathematics: Faculty Publications

Consider a reductive linear algebraic group G acting linearly on a polynomial ring S over an infinite field; key examples are the general linear group, the symplectic group, the orthogonal group, and the special linear group, with the classical representations as inWeyl’s book: For the general linear group, consider a direct sum of copies of the standard representation and copies of the dual; in the other cases, take copies of the standard representation. The invariant rings in the respective cases are determinantal rings, rings defined by Pfaffians of alternating matrices, symmetric determinantal rings and the Plücker coordinate rings of Grassmannians; …


Pathogen Emergence As Complex Biological Invasion: Lessons From Dynamical Systems Modeling, Sudam Surasinghe, Marisabel Rodriguez, Victor Meszaros, Jane Molofsky, Salvador Almagro-Moreno, Brandon Ogbunugafor Jul 2023

Pathogen Emergence As Complex Biological Invasion: Lessons From Dynamical Systems Modeling, Sudam Surasinghe, Marisabel Rodriguez, Victor Meszaros, Jane Molofsky, Salvador Almagro-Moreno, Brandon Ogbunugafor

Northeast Journal of Complex Systems (NEJCS)

Infectious disease emergence has become the target of cross-disciplinary efforts
that aim to understand and predict the shape of outbreaks. The many challenges
involved with the prediction of disease emergence events is a characteristic that in-
fectious diseases share with biological invasions in many subfields of ecology (e.g.,
how certain plants are able to successfully invade a new niche). Like infectious
diseases, biological invasions by plants and animals involve interactions between
agents (pathogens and plants in their respective cases) and a recipient niche. In
this study, we examine the problem of pathogen emergence through the lens of a
framework first …


Numerical Design And Optimization Of Near-Infrared Band- Pass Filter, Hafiza Syeeda Faiza, Ghazi Aman Nowsherwan, Basem A. Abu Izneid, Muhammad Azhar, Saira Riaz, Syed Sajjad Hussain, Saira Ikram, Mohsin Khan, Shahzad Naseem, Mohammad Kanan, Ibrahim M. Mansour Jul 2023

Numerical Design And Optimization Of Near-Infrared Band- Pass Filter, Hafiza Syeeda Faiza, Ghazi Aman Nowsherwan, Basem A. Abu Izneid, Muhammad Azhar, Saira Riaz, Syed Sajjad Hussain, Saira Ikram, Mohsin Khan, Shahzad Naseem, Mohammad Kanan, Ibrahim M. Mansour

Applied Mathematics & Information Sciences

Band-pass filters functioning in the near-infrared (IR) range are desired for laser technology, multi-photon fluorescence, and IR imaging applications. In this study, we have designed four band-pass filters in the near Infrared spectrum (900-1200 nm) by vertically stacking different high and low-index materials. The band-pass filters are modelled by Essential Macleod software with different thicknesses. The layer’s thicknesses were optimized in such a way to provide the negligible reflectance and maximum transmission on the front side. All the simulated band-pass filters exhibit high transmittance, but TiO2/Al2O3 and Ta2O5/Al2O3 outperforms other modelled structure in terms of performance due to the better …


Modified Geometries, Clifford Algebras And Graphs: Their Impact On Discreteness, Locality And Symmetr, Roman Sverdlov Jul 2023

Modified Geometries, Clifford Algebras And Graphs: Their Impact On Discreteness, Locality And Symmetr, Roman Sverdlov

Mathematics & Statistics ETDs

In this dissertation I will explore the question whether various entities commonly used in quantum field theory can be “constructed". In particular, can spacetime be “constructed" out of building blocks, and can Berezin integral be “constructed" in terms of Riemann integrals.

As far as “constructing" spacetime out of building blocks, it has been attempted by multiple scientific communities and various models were proposed. But the common downfall is they break the principles of relativity. I will explore the ways of doing so in such a way that principles of relativity are respected. One of my approaches is to replace points …


Accurate Covariance Estimation For Pose Data From Iterative Closest Point Algorithm, Rick H. Yuan, Clark N. Taylor, Scott L. Nykl Jul 2023

Accurate Covariance Estimation For Pose Data From Iterative Closest Point Algorithm, Rick H. Yuan, Clark N. Taylor, Scott L. Nykl

Faculty Publications

One of the fundamental problems of robotics and navigation is the estimation of the relative pose of an external object with respect to the observer. A common method for computing the relative pose is the iterative closest point (ICP) algorithm, where a reference point cloud of a known object is registered against a sensed point cloud to determine relative pose. To use this computed pose information in downstream processing algorithms, it is necessary to estimate the uncertainty of the ICP output, typically represented as a covariance matrix. In this paper, a novel method for estimating uncertainty from sensed data is …


Advanced Prognostic Modeling For Breast Cancer Patients: Leveraging Data-Driven Approaches For Survival Analysis, Theophilus Gyedu Baidoo Jul 2023

Advanced Prognostic Modeling For Breast Cancer Patients: Leveraging Data-Driven Approaches For Survival Analysis, Theophilus Gyedu Baidoo

Theses and Dissertations

Breast cancer is the second most prevalent form of cancer in women in the United States. Each year, about 264,000 cases of breast cancer are diagnosed in women and of this number, about 42,000 women lose their lives as reported by the Centers for Disease Control and Prevention. Early detection and effective treatment are crucial for improving survival rates and reducing mortality. This study aimed to explore the influential factors that may risk the survival of women with the disease and compare their predictive abilities using several error and performance metrics. The study uses a dataset from the National Cancer …


Identification Of Heart Disorders With Symbolic Aggregate Approximation, Moses K. Owusu Jul 2023

Identification Of Heart Disorders With Symbolic Aggregate Approximation, Moses K. Owusu

Theses and Dissertations

This project is an application of the Symbolic Aggregate Approximation (SAX) to 1000 fragments of ECG signals for 45 patients (42% females aged between 23 and 89 years and 58% males aged 32 to 89 years) using data obtained from the MIH-BIH Arrhythmia database to recognize cardiac health disorders. Data include a normal sinus rhythm, pacemaker rhythm and ECG readings for 15 heart disorders, making 17 in total. The aim is to use SAX to classify heart disorders using ECG signal, that analyzes QRS-complexes by first splitting the time series into smaller equally sized segments using the Piecewise Aggregate Approximation …


The Metabolomics Workbench File Status Website: A Metadata Repository Promoting Fair Principles Of Metabolomics Data, Christian D. Powell, Hunter N. B. Moseley Jul 2023

The Metabolomics Workbench File Status Website: A Metadata Repository Promoting Fair Principles Of Metabolomics Data, Christian D. Powell, Hunter N. B. Moseley

Markey Cancer Center Faculty Publications

Background: An updated version of the mwtab Python package for programmatic access to the Metabolomics Workbench (MetabolomicsWB) data repository was released at the beginning of 2021. Along with updating the package to match the changes to MetabolomicsWB’s ‘mwTab’ file format specification and enhancing the package’s functionality, the included validation facilities were used to detect and catalog file inconsistencies and errors across all publicly available datasets in MetabolomicsWB.

Results: The MetabolomicsWB File Status website was developed to provide continuous validation of MetabolomicsWB data files and a useful interface to all found inconsistencies and errors. This list of detectable issues/errors include format …


Assessment On Usage Of The Library Website Resources By Students In The Information Studies Programme At The University Of Dar Es Salaam, Hosea N. Mungwabi Jun 2023

Assessment On Usage Of The Library Website Resources By Students In The Information Studies Programme At The University Of Dar Es Salaam, Hosea N. Mungwabi

Tanzania Journal of Engineering and Technology (TJET)

The study investigated students' usage of electronic resources available on the UDSM Library's website. Specifically, the study determined whether information studies students were aware of the electronic resources, how frequently they used them, and whether their demographic characteristics influenced their usage. The study also examined the students' satisfaction with the functional and non functional attributes of the website resources. A mixed-methods research design combining both qualitative and quantitative data collection methods was used. The sample consisted of 118 student respondents who were selected using a stratified random sampling technique. The data were collected through questionnaires and interviews with class representatives …


Deep Learning Model Compression Techniques: Advances, Opportunities, And Perspective, Hubert Msuya Jun 2023

Deep Learning Model Compression Techniques: Advances, Opportunities, And Perspective, Hubert Msuya

Tanzania Journal of Engineering and Technology (TJET)

Recently, deep learning (DL) models have excelled in a wide range of fields. All of these successes are built on intricate DL models. The hundreds of millions or even billions of parameters and high-performance computing graphical processing units or tensor processing units are largely responsible for their achievement. DL model integration into real-time devices with tight latency limitations, limited memory, and power-constrained requirements is the key driving force behind investigation of DL model compression techniques. Also, there is an increase in data availability that encourages multimodal fusion in DL models to boost the models' predictive accuracy. In order to create …


Performance Evaluation Of Full Array, Sub-Array And Overlapped Sub-Array Hybrid Beamforming Architectures For Massive Mimo Systems, Godwin Mruma Gadiel Jun 2023

Performance Evaluation Of Full Array, Sub-Array And Overlapped Sub-Array Hybrid Beamforming Architectures For Massive Mimo Systems, Godwin Mruma Gadiel

Tanzania Journal of Engineering and Technology (TJET)

The technological advancement in wireless communication, promises high data rate for end users. This has led to the possibility of smart cities, inter connected vehicles, and virtual reality applications. One of the recent technologies in wireless communication is massive MIMO where large number of antennas are deployed at the transmitter or receiver. This is possible due to the use of mmWave in wireless communication. With massive MIMO, beamforming technique can be employed in the communication system. Beamforming is the ability of communication system to direct power to the intended users and to cancel power at non-intended users and thus significantly …


Continuous Time Dynamic Mode Decomposition In The Presence Of Partial Knowledge And Streaming Data, Efrain H. Gonzalez Jun 2023

Continuous Time Dynamic Mode Decomposition In The Presence Of Partial Knowledge And Streaming Data, Efrain H. Gonzalez

USF Tampa Graduate Theses and Dissertations

Dynamic mode decomposition (DMD) is a physically interpretable data driven technique for modeling dynamical systems. The DMD method uses time series data where each data point is referred to as a snapshot and represents the value of the state at a particular moment in time. The important patterns found in the data are extracted and then used to create a model for the system. Once the important pieces have been obtained reduced order modeling can be used to reduce the complexity of the model.

But, DMD has evolved since its inception. After its association with the Koopman operator, DMD has …


Waste Treatment Facility Location For Hotel Chains, Dolores R. Santos-Peñate, Rafael R. Suárez-Vega, Carmen Florido De La Nuez Jun 2023

Waste Treatment Facility Location For Hotel Chains, Dolores R. Santos-Peñate, Rafael R. Suárez-Vega, Carmen Florido De La Nuez

ITSA 2022 Gran Canaria - 9th Biennial Conference: Corporate Entrepreneurship and Global Tourism Strategies After Covid 19

Tourism generates huge amounts of waste. About half of the waste generated by hotels is food and garden bio-waste. This bio-waste can be used to make compost and pellets. In turn, pellets can be used as an absorbent material in composters and as an energy source. We consider the problem of locating composting and pellet-making facilities so that the bio-waste generated by a chain of hotels can be managed at or close to the generation points. An optimization model is applied to locate the facilities and allocate the waste and products, and several scenarios are analysed. The study shows that, …


Said-Ball Polynomials For Solving Linear Systems Of Ordinary Differential Equations, Mubark Al-Subaai Dr., Ahmes Saleh Kherd Jun 2023

Said-Ball Polynomials For Solving Linear Systems Of Ordinary Differential Equations, Mubark Al-Subaai Dr., Ahmes Saleh Kherd

Emirates Journal for Engineering Research

Said-Ball polynomials with collocation method are used to numerically solve a system of linear ordinary differential equations. The matrix forms of Said-Ball polynomials of the solution, derivatives, and conditions are done. The linear system of ordinary differential equations with appropriate conditions is reduced to the linear algebraic equations system with unknown Said-Ball coefficients. Solving the resulting system determines the coefficients of Said-Ball polynomials. By Substituting these values in the polynomial, we get the problem's exact and approximate solutions. The obtaining numerical results show the proposed method's accuracy and reliability when compared with the other works and exact solutions


Temporality-Induced Chaos In The Kuramoto Model, Keanu Mason Rock, Hamza Dirie, Sean P. Cornelius Jun 2023

Temporality-Induced Chaos In The Kuramoto Model, Keanu Mason Rock, Hamza Dirie, Sean P. Cornelius

Northeast Journal of Complex Systems (NEJCS)

Switched dynamical systems have been extensively studied in engineering literature in the context of system control. In these systems, the dynamical laws change between different subsystems depending on the environment, a process that is known to produce emergent behaviors---notably chaos. These dynamics are analogous to those of temporal networks, in which the network topology changes over time, thereby altering the dynamics on the network. It stands to reason that temporal networks may therefore produce emergent chaos and other exotic behaviors unanticipated in static networks, yet concrete examples remain elusive. Here, we present a minimal example of a networked system in …


Extending The Spectral Difference Method With Divergence Cleaning (Sddc) To The Hall Mhd Equations, Russell J. Hankey, Kuangxu Chen, Chunlei Liang Jun 2023

Extending The Spectral Difference Method With Divergence Cleaning (Sddc) To The Hall Mhd Equations, Russell J. Hankey, Kuangxu Chen, Chunlei Liang

Northeast Journal of Complex Systems (NEJCS)

The Hall Magnetohydrodynamic (MHD) equations are an extension of the standard MHD equations that include the “Hall” term from the general Ohm’s law. The Hall term decouples ion and electron motion physically on the ion inertial length scales. Implementing the Hall MHD equations in a numerical solver allows more physical simulations for plasma dynamics on length scales less than the ion inertial scale length but greater than the electron inertial length. The present effort is an important step towards producing physically correct results to important problems, such as the Geospace Environmental Modeling (GEM) Magnetic Reconnection problem. The solver that is …


Periodic, Nonperiodic, And Chaotic Solutions For A Class Of Difference Equations With Negative Feedback, Benjamin B. Kennedy Jun 2023

Periodic, Nonperiodic, And Chaotic Solutions For A Class Of Difference Equations With Negative Feedback, Benjamin B. Kennedy

Math Faculty Publications

We study the scalar difference equation x(k + 1) = x(k) + (f(x(k - N))) / N,

where f is nonincreasing with negative feedback. This equation is a discretization of the well-studied differential delay equation x'(t) = f(x(t - 1)).

We examine explicit families of such equations for which we can find, for infinitely many values of N and appropriate parameter values, various dynamical behaviors including periodic solutions with large numbers of sign changes per minimal period, solutions that do not converge to periodic solutions, and chaos. We contrast these behaviors with the dynamics of the limiting differential equation. Our …


Using Medicare Claims To Estimate Risk-Adjusted Performance Of Pennsylvania Trauma Centers, Alexis M Zebrowski, Phillipe Loher, David G Buckler, Isidore Rigoutsos, Brendan G Carr, Douglas J Wiebe Jun 2023

Using Medicare Claims To Estimate Risk-Adjusted Performance Of Pennsylvania Trauma Centers, Alexis M Zebrowski, Phillipe Loher, David G Buckler, Isidore Rigoutsos, Brendan G Carr, Douglas J Wiebe

Computational Medicine Center Faculty Papers

Trauma centers use registry data to benchmark performance using a standardized risk adjustment model. Our objective was to utilize national claims to develop a risk adjustment model applicable across all hospitals, regardless of designation or registry participation. Patients from 2013-14 Pennsylvania Trauma Outcomes Study (PTOS) registry data were probabilistically matched to Medicare claims using demographic and injury characteristics. Pairwise comparisons established facility linkages and matching was then repeated within facilities to link records. Registry models were estimated using GLM and compared with five claims-based LASSO models: demographics, clinical characteristics, diagnosis codes, procedures codes, and combined demographics/clinical characteristics. Area under the …


(R1954) Fractional Order On Modeling The Transmission Of Devastative Covid-19 Infection: Efficacy Of Vaccination, Ashutosh Rajput, Tanvi ., Rajiv Aggarwal, Arpana Sharma, Shiv Kumar Sahdev, Manoj Kumar, Jaimala . Jun 2023

(R1954) Fractional Order On Modeling The Transmission Of Devastative Covid-19 Infection: Efficacy Of Vaccination, Ashutosh Rajput, Tanvi ., Rajiv Aggarwal, Arpana Sharma, Shiv Kumar Sahdev, Manoj Kumar, Jaimala .

Applications and Applied Mathematics: An International Journal (AAM)

The second wave of COVID-19 is an unprecedented condition in India and began in mid February 2021. Individuals who were already suffering from other comorbidities were found with lung infection, and hence, the number of disease induced deaths were rising faster during the second wave in relation to the first wave. This paper has proposed a mathematical model with fractional order derivatives by correlating the model based number of infectives with the real number of infectives in India. For the system of fractional differential equations, a disease-free state has been computed and proved to be locally asymptotically stable with certain …


(R1951) Numerical Solution For A Class Of Nonlinear Emden-Fowler Equations By Exponential Collocation Method, Mohammad Aslefallah, Saeid Abbasbandy, Şuayip Yüzbaşi Jun 2023

(R1951) Numerical Solution For A Class Of Nonlinear Emden-Fowler Equations By Exponential Collocation Method, Mohammad Aslefallah, Saeid Abbasbandy, Şuayip Yüzbaşi

Applications and Applied Mathematics: An International Journal (AAM)

In this research, exponential approximation is used to solve a class of nonlinear Emden-Fowler equations. This method is based on the matrix forms of exponential functions and their derivatives using collocation points. To demonstrate the usefulness of the method, we apply it to some different problems. The numerical approximate solutions are compared with available (existing) exact (analytical) solutions to show the accuracy of the proposed method. The method has been checked with several examples to show its validity and reliability. The reported examples illustrate that the method is reasonably efficient and accurate.


(R1966) Semi Analytical Approach To Study Mathematical Model Of Atmospheric Internal Waves Phenomenon, Patel Yogeshwari, Jayesh M. Dhodiya Jun 2023

(R1966) Semi Analytical Approach To Study Mathematical Model Of Atmospheric Internal Waves Phenomenon, Patel Yogeshwari, Jayesh M. Dhodiya

Applications and Applied Mathematics: An International Journal (AAM)

This research aims to study atmospheric internal waves which occur within the fluid rather than on the surface. The mathematical model of the shallow fluid hypothesis leads to a coupled nonlinear system of partial differential equations. In the shallow flow model, the primary assumption is that vertical size is smaller than horizontal size. This model can precisely replicate atmospheric internal waves because waves are dispersed over a vast horizontal area. A semi-analytical approach, namely modified differential transform, is applied successfully in this research. The proposed method obtains an approximate analytical solution in the form of convergent series without any linearization, …


(R1997) Distance Measures Of Complex Fermatean Fuzzy Number And Their Application To Multi-Criteria Decision-Making Problem, V. Chinnadurai, S. Thayalan, A. Bobin Jun 2023

(R1997) Distance Measures Of Complex Fermatean Fuzzy Number And Their Application To Multi-Criteria Decision-Making Problem, V. Chinnadurai, S. Thayalan, A. Bobin

Applications and Applied Mathematics: An International Journal (AAM)

Multi-criteria decision-making (MCDM) is the most widely used decision-making method to solve many complex problems. However, classical MCDM approaches tend to make decisions when the parameters are imprecise or uncertain. The concept of a complex fuzzy set is new in the field of fuzzy set theory. It is a set that can collect and interpret the membership grades from the unit circle in a plane instead of the interval [0,1]. CFS cannot deal with membership and non-membership grades, while complex intuitionistic fuzzy set and complex Pythagorean fuzzy set works only for a limited range of values. The concept of a …


(R2033) Resonant Curve Due To Perturbations Of Geo-Synchronous Satellite Including Effect Of Earth’S Equatorial Ellipticity, Sushil Yadav, Mukesh Kumar, Virendra Kumar Jun 2023

(R2033) Resonant Curve Due To Perturbations Of Geo-Synchronous Satellite Including Effect Of Earth’S Equatorial Ellipticity, Sushil Yadav, Mukesh Kumar, Virendra Kumar

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we have investigated resonant curve due to frequencies − angular rate of rotation of the Earth and the rate of change of Earth’s equatorial ellipticity parameter. Perturbation equations are used to convert the non-linear equations of motion of geo-synchronous satellite to the linear form. With the help of graphs, we have shown the effect of Earth’s equatorial ellipticity parameter on oscillatory amplitude and variation in orbital radius of satellite. By defining different perturbations, we have also drawn resonant curve due to frequencies steady-state orbital angular rate of satellite and the rate of change of Earth’s equatorial ellipticity …


(R2052) Flow Patterns For Newtonian And Non-Newtonian Fluids In A Cylindrical Pipe, Erick Sanchez, Dambaru Bhatta Jun 2023

(R2052) Flow Patterns For Newtonian And Non-Newtonian Fluids In A Cylindrical Pipe, Erick Sanchez, Dambaru Bhatta

Applications and Applied Mathematics: An International Journal (AAM)

A fully developed laminar steady flow of an incompressible, viscous fluid in a horizontal cylindrical pipe is considered here. Flow patterns for an incompressible, viscous fluid for both Newtonian and non-Newtonian fluids such as shear-thinning, shear-thickening and Bingham plastic fluids are analyzed in this study. Assuming that the flow is only due to the wall shear stress and the pressure drop, the velocity component in the axial direction for these cases is derived. Computational results of the velocity profiles for various cases are obtained using MATLAB and presented in graphical forms. It is observed that the velocity profile is parabolic …


(R1987) Hermite Wavelets Method For System Of Linear Differential Equations, Inderdeep Singh, Manbir Kaur Jun 2023

(R1987) Hermite Wavelets Method For System Of Linear Differential Equations, Inderdeep Singh, Manbir Kaur

Applications and Applied Mathematics: An International Journal (AAM)

In this research paper, we present an accurate technique for solving the system of linear differential equations. Such equations often arise as a result of modeling in many systems and applications of engineering and science. The proposed scheme is based on Hermite wavelets basis functions and operational matrices of integration. The demonstrated scheme is simple as it converts the problem into algebraic matrix equation. To validate the applicability and efficacy of the developed scheme, some illustrative examples are also considered. The results so obtained with the help of the present proposed numerical technique by using Hermite wavelets are observed to …


(R1975) Map/Ph(1), Ph(2)/2 Queue With Multiple Vacation, Optional Service, Consultations And Interruptions, G. Ayyappan, S. Sankeetha Jun 2023

(R1975) Map/Ph(1), Ph(2)/2 Queue With Multiple Vacation, Optional Service, Consultations And Interruptions, G. Ayyappan, S. Sankeetha

Applications and Applied Mathematics: An International Journal (AAM)

Two types of services are explored in this paper: regular server and main server, both of which provide both regular and optional services. Customers arrive using the Markovian Arrival Process (MAP), and service time is allocated based on phase type. The regular server uses the main server as a resource. Customers’ service at the primary server is disrupted as a result. When the queue size is empty, the main server can take several vacations. This system has been represented as a QBD Process that investigates steady state with the use of matrix analytic techniques, employing finite-dimensional block matrices. Our model’s …


On Colorings And Orientations Of Signed Graphs, Daniel Slilaty Jun 2023

On Colorings And Orientations Of Signed Graphs, Daniel Slilaty

Mathematics and Statistics Faculty Publications

A classical theorem independently due to Gallai and Roy states that a graph G has a proper k-coloring if and only if G has an orientation without coherent paths of length k. An analogue of this result for signed graphs is proved in this article.


Detecting Coherent Transport Structures In Ocean Surface Flows, Leah Hoogstra Jun 2023

Detecting Coherent Transport Structures In Ocean Surface Flows, Leah Hoogstra

Master's Theses

Ocean surface transport plays a critical role in marine ecosystems, influencing the complex spatiotemporal patterns of both marine species and pollutants. The theory of Lagrangian coherent structures (LCSs) aims to identify fundamental patterns within time-dependent, nonlinear fluid flows. LCSs are material surfaces that act as dividing lines which fluid does not cross for a relevant period of time. LCS theory is still under active development, and there are multiple proposed ways to mathematically determine an LCS. Each proposed mathematical definition aims to capture the same physical properties, and some capture those properties more successfully and consistently than others. Here we …


Analyzing Tortuosity In Patterns Formed By Colonies Of Embryonic Stem Cells Using Topological Data Analysis, Jackie Driscoll Jun 2023

Analyzing Tortuosity In Patterns Formed By Colonies Of Embryonic Stem Cells Using Topological Data Analysis, Jackie Driscoll

Master's Theses

Pluripotent stem cells have been observed to segregate into Turing-like patterns during the early stages of Dox-inducible hiPSC differentiation. In this thesis, we de- velop a tool to quantify the tortuosity in the patterns formed by colonies of pluripo- tent stem cells using methods from topological data analysis. We use clustering techniques and the mapper algorithm to create simplicial complexes representing samples of cells and detail a method of evaluating the tortuosity of these complexes. We use the resulting persistence landscapes and their associated norms to evaluate experimental data and simulated data from an agent based model. This thesis finds …


Gradient-Based Trade-Off Design For Engineering Applications, Lena A. Royster, Gene Hou Jun 2023

Gradient-Based Trade-Off Design For Engineering Applications, Lena A. Royster, Gene Hou

Mechanical & Aerospace Engineering Faculty Publications

The goal of the trade-off design method presented in this study is to achieve newly targeted performance requirements by modifying the current values of the design variables. The trade-off design problem is formulated in the framework of Sequential Quadratic Programming. The method is computationally efficient as it is gradient-based, which, however, requires the performance functions to be differentiable. A new equation to calculate the scale factor to control the size of the design variables is introduced in this study, which can ensure the new design achieves the targeted performance objective. Three formal approaches are developed in this study for trade-off …