Applied Mathematics Commons^™

Preliminary Analysis Of An Agent-Based Model For A Tick-Borne Disease, Holly Gaff

Biological Sciences Faculty Publications

Ticks have a unique life history including a distinct set of life stages and a single blood meal per life stage. This makes tick-host interactions more complex from a mathematical perspective. In addition, any model of these interactions must involve a significant degree of stochasticity on the individual tick level. In an attempt to quantify these relationships, I have developed an individual-based model of the interactions between ticks and their hosts as well as the transmission of tick-borne disease between the two populations. The results from this model are compared with those from previously published differential equation based population models. …

An Extensible Mathematical Model Of Glucose Metabolism, Caleb L. Adams

Mathematics & Statistics Theses & Dissertations

The American Diabetes Association reports that diabetes is the fifth leading cause of death by disease in the United States. An estimated 23.6 million individuals, or seven percent of the population, have diabetes. Nearly one-third are unaware that they have the disease. The total of the direct and indirect medical costs associated with diabetes in 2007 was projected to be $174 billion, or approximately one out of every ten health care dollars.

One must understand the glucose regulatory system of the healthy body to understand diabetes. Blood glucose concentration returns to a constant level after eating and is maintained during …

A Least Squares Closure Approximation For Liquid Crystalline Polymers, Traci Ann Sievenpiper

Mathematics & Statistics Theses & Dissertations

An introduction to existing closure schemes for the Doi-Hess kinetic theory of liquid crystalline polymers is provided. A new closure scheme is devised based on a least squares fit of a linear combination of the Doi, Tsuji-Rey, Hinch-Leal I, and Hinch-Leal II closure schemes. The orientation tensor and rate-of-strain tensor are fit separately using data generated from the kinetic solution of the Smoluchowski equation. The known behavior of the kinetic solution and existing closure schemes at equilibrium is compared with that of the new closure scheme. The performance of the proposed closure scheme in simple shear flow for a variety …

Set-Based Corral Control In Stochastic Dynamical Systems: Making Almost Invariant Sets More Invariant, Eric Forgoston, Lora Billings, Philip Yecko, Ira Schwartz

Department of Mathematics Faculty Scholarship and Creative Works

We consider the problem of stochastic prediction and control in a time-dependent stochastic environment, such as the ocean, where escape from an almost invariant region occurs due to random fluctuations. We determine high-probability control-actuation sets by computing regions of uncertainty, almost invariant sets, and Lagrangian coherent structures. The combination of geometric and probabilistic methods allows us to design regions of control, which provide an increase in loitering time while minimizing the amount of control actuation. We show how the loitering time in almost invariant sets scales exponentially with respect to the control actuation, causing an exponential increase in loitering times …

A “Peak” At The Algorithm Behind “Peaklet Analysis” Software, Bruce Kessler

Mathematics Faculty Publications

In response to a problem posed by faculty at the Applied Physics Institute at Western Kentucky University, the speaker has developed an algorithm for providing an automated analysis of spectrum data for the purpose of determining the elemental composition of the item generating the data. A full, non-provisional patent application has been filed on the idea, and a full marketing campaign has started to license software implementing the algorithm. This presentation will give a brief explanation of the mathematics in use in the algorithm, and will give some examples of the software in action.

Quantum Mechanical Model Of The Hydrogen Atom, Andres Ortiz^, Snehanshu Saha*

COURI Symposium Abstracts, Spring 2011

The quantum mechanical wave function of an object under a certain potential is determined by the Schrödinger equation. It is known that the latter equation can be solved analytically only for a finite number of distinct potentials, being a Coulomb potential one of them. For an electron in a hydrogen atom, we analytically find the angular parts of its wave function by the usual method. Under the appropriate change of variable, the radial part of the equation is turned into a Legendre differential equation whose solutions are Legendre polynomials. Using finite difference method and shooting method taking into account physically …

Modeling Of Bacillus Spores: Inactivation And Outgrowth, Alexis X. Hurst

Theses and Dissertations

This research models and analyzes the thermochemical damage produced in Bacillus spores by short, high-temperature exposures as well the repair process within damaged Bacillus spores. Thermochemical damage in spores is significantly due to reaction with water, hydrolysis reactions. Applying heat to the spore causes absorbed and chemically bound water molecules become mobile within the spore. These mobile water molecules react by hydrolysis reactions to degrade DNA and enzyme molecules in the spore. In order to survive the thermal inactivation, the spore must repair the damaged DNA during spore germination. The DNA repair process, as well as other germination functions, is …

Quantitative Interpretation Of A Genetic Model Of Carcinogenesis Using Computer Simulations, Donghai Dai, Brandon Beck, Xiaofang Wang, Cory Howk, Yi Li

Mathematics and Statistics Faculty Publications

The genetic model of tumorigenesis by Vogelstein et al. (V theory) and the molecular definition of cancer hallmarks by Hanahan and Weinberg (W theory) represent two of the most comprehensive and systemic understandings of cancer. Here, we develop a mathematical model that quantitatively interprets these seminal cancer theories, starting from a set of equations describing the short life cycle of an individual cell in uterine epithelium during tissue regeneration. The process of malignant transformation of an individual cell is followed and the tissue (or tumor) is described as a composite of individual cells in order to quantitatively account for intra-tumor …

A Primer On Chaos And Fractals, Bruce Kessler

Mathematics Faculty Publications

This is a prelude to a performance of the play "Arcadia" exclusively for the science and math majors of Lipscomb University. One of the main characters of the story is a mathematical genius, and has realized the power and limitations of iterations in generating mathematical models and structures, although she is living in the early 1800's. This talk gives an introduction to the ideas of chaos theory, fractals, and randomness.

Maximal Sensitive Dependence And The Optimal Path To Epidemic Extinction, Eric Forgoston, Simone Bianco, Leah B. Shaw, Ira B. Schwartz

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

Extinction of an epidemic or a species is a rare event that occurs due to a large, rare stochastic fluctuation. Although the extinction process is dynamically unstable, it follows an optimal path that maximizes the probability of extinction. We show that the optimal path is also directly related to the finite-time Lyapunov exponents of the underlying dynamical system in that the optimal path displays maximum sensitivity to initial conditions. We consider several stochastic epidemic models, and examine the extinction process in a dynamical systems framework. Using the dynamics of the finite-time Lyapunov exponents as a constructive tool, we demonstrate that …

Complete Characterizations Of Local Weak Sharp Minima With Applications To Semi-Infinite Optimization And Complementarity, Boris S. Mordukhovich, Naihua Xiu, Jinchuan Zhou

Mathematics Research Reports

In this paper we identify a favorable class of nonsmooth functions for which local weak sharp minima can be completely characterized in terms of normal cones and subdifferentials, or tangent cones and subderivatives, or their mixture in finite-dimensional spaces. The results obtained not only significantly extend previous ones in the literature, but also allow us to provide new types of criteria for local weak sharpness. Applications of the developed theory are given to semi-infinite programming and to semi-infinite complementarity problems.

Global Well-Posedness And Asymptotic Behavior Of A Class Of Initial-Boundary-Value Problems Of The Kdv Equation On A Finite Domain, Ivonne Rivas, Muhammad Usman, Bingyu Zhang

Mathematics Faculty Publications

In this paper, we study a class of initial boundary value problem (IBVP) of the Korteweg- de Vries equation posed on a ?nite interval with nonhomogeneous boundary conditions. The IBVP is known to be locally well-posed, but its global L2 a priori estimate is not available and therefore it is not clear whether its solutions exist globally or blow up in finite time. It is shown in this paper that the solutions exist globally as long as their initial value and the associated boundary data are small, and moreover, those solutions decay exponentially if their boundary data decay exponentially.

Projective-Planar Graphs With No K3,4-Minor, John Maharry, Dan Slilaty

Mathematics and Statistics Faculty Publications

An exact structure is described to classify the projective‐planar graphs that do not contain a K3, 4‐minor.

Sharp Asymptotics Of The Lp Approximation Error For Interpolation On Block Partitions, Yuliya Babenko, Tatyana Leskevich, Jean-Marie Mirebeau

Faculty Articles

Adaptive approximation (or interpolation) takes into account local variations in the behavior of the given function, adjusts the approximant depending on it, and hence yields the smaller error of approximation. The question of constructing optimal approximating spline for each function proved to be very hard. In fact, no polynomial time algorithm of adaptive spline approximation can be designed and no exact formula for the optimal error of approximation can be given. Therefore, the next natural question would be to study the asymptotic behavior of the error and construct asymptotically optimal sequences of partitions. In this paper we provide sharp asymptotic …

Waves In Microstructured Solids: A Unified Viewpoint Of Modelling, Arkadi Berezovski, Juri Engelbrecht, Mihhail Berezovski

Publications

The basic ideas for describing the dispersive wave motion in microstructured solids are discussed in the one-dimensional setting because then the differences between various microstructure models are clearly visible. An overview of models demonstrates a variety of approaches, but the consistent structure of the theory is best considered from the unified viewpoint of internal variables. It is shown that the unification of microstructure models can be achieved using the concept of dual internal variables.

On The Stability Of A Microstructure Model, Mihhail Berezovski, Arkadi Berezovski

Publications

The asymptotic stability of solutions of the Mindlin-type microstructure model for solids is analyzed in the paper. It is shown that short waves are asymptotically stable even in the case of a weakly non-convex free energy dependence on microdeformation.

Tangential Extremal Principles For Finite And Infinite Systems Of Sets, Ii: Applications To Semi-Infinite And Multiobjective Optimization, Boris S. Mordukhovich, Hung M. Phan

Mathematics Research Reports

This paper contains selected applications of the new tangential extremal principles and related results developed in [20] to calculus rules for infinite intersections of sets and optimality conditions for problems of semi-infinite programming and multiobjective optimization with countable constraints.

On The (Non)-Integrability Of The Perturbed Kdv Hierarchy With Generic Self-Consistent Sources, Vladimir Gerdjikov, Georgi Grahovski, Rossen Ivanov

Conference papers

Non-holonomic deformations of integrable equations of the KdV hierarchy are studied by using the expansions over the so-called "squared solutions" (squared eigenfunctions). Such deformations are equivalent to perturbed models with external (self-consistent) sources. In this regard, the KdV6 equation is viewed as a special perturbation of KdV equation. Applying expansions over the symplectic basis of squared eigenfunctions, the integrability properties of the KdV hierarchy with generic self-consistent sources are analyzed. This allows one to formulate a set of conditions on the perturbation terms that preserve the integrability. The perturbation corrections to the scattering data and to the corresponding action-angle variables …

Which Chessboards Have A Closed Knight's Tour Within The Rectangular Prism?, Joseph Demaio, Mathew Bindia

Faculty Articles

A closed knight's tour of a chessboard uses legal moves of the knight to visit every square exactly once and return to its starting position. In 1991 Schwenk completely classified the m x n rectangular chessboards that admit a closed knight's tour. In honor of the upcoming twentieth anniversary of the publication of Schwenk's paper, this article extends his result by classifying the i x j x k rectangular prisms that admit a closed knight's tour.

Analysis Of The Quasi-Nonlocal Approximation Of Linear And Circular Chains In The Plane, Pavel Bělík, Mitchell Luskin

Faculty Authored Articles

We give an analysis of the stability and displacement error for linear and circular atomistic chains in the plane when the atomistic energy is approximated by the Cauchy-Born continuum energy and by the quasi-nonlocal atomistic-to-continuum coupling energy. We consider atomistic energies that include Lennard-Jones type nearest neighbor and next nearest neighbor pair-potential interactions. Previous analyses for linear chains have shown that the Cauchy-Born and quasi-nonlocal approximations reproduce (up to the order of the lattice spacing) the atomistic lattice stability for perturbations that are constrained to the line of the chain. However, we show that the Cauchy-Born and quasi-nonlocal approximations give …

Error Control Of Iterative Linear Solvers For Integrated Groundwater Models, Matthew Dixon, Z Bai, C F. Brush, F I. Chung, E C. Dogrul, T M. Kadir

Business Analytics and Information Systems

An open problem that arises when using modern iterative linear solvers, such as the preconditioned conjugate gradient method or Generalized Minimum RESidual (GMRES) method, is how to choose the residual tolerance in the linear solver to be consistent with the tolerance on the solution error. This problem is especially acute for integrated groundwater models, which are implicitly coupled to another model, such as surface water models, and resolve both multiple scales of flow and temporal interaction terms, giving rise to linear systems with variable scaling. This article uses the theory of “forward error bound estimation” to explain the correspondence between …

Tangential Extremal Principles For Finite And Infinite Systems Of Sets, I: Basic Theory, Boris S. Mordukhovich, Hung M. Phan

Mathematics Research Reports

In this paper we develop new extremal principles in variational analysis that deal with finite and infinite systems of convex and nonconvex sets. The results obtained, unified under the name of tangential extremal principles, combine primal and dual approaches to the study of variational systems being in fact first extremal principles applied to infinite systems of sets. The first part of the paper concerns the basic theory of tangential extremal principles while the second part presents applications to problems of semi-infinite programming and multiobjective optimization.

Research In Mathematics Educational Technology: Current Trends And Future Demands, Shannon O. Driskell, Robert N. Ronau, Christopher R. Rakes, Sarah B. Bush, Margaret L. Niess, David K. Pugalee

Mathematics Faculty Publications

This systematic review of mathematics educational technology literature identified 1356 manuscripts addressing the integration of educational technology into mathematics instruction. The manuscripts were analyzed using three frameworks (Research Design, Teacher Knowledge, and TPACK) and three supplementary lenses (Data Sources, Outcomes, and NCTM Principles) to produce a database to support future research syntheses and meta-analyses. Preliminary analyses of student and teacher outcomes (e.g., knowledge, cognition, affect, and performance) suggest that the effects of incorporating graphing calculator and dynamic geometry technologies have been abundantly studied; however, the usefulness of the results was often limited by missing information regarding measures of validity, reliability, …

Modeling Diverse Physics Of Nanoparticle Self-Assembly In Pulsed Laser-Irradiated Metallic Films, Mikhail Khenner

Mathematics Faculty Publications

Presents physics behind dewetting of thin liquid films and mathematical/computational modeling tools (Educational/Research presentation for senior physics majors).

Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu T. Tekalign, Margo S. Levine

Mathematics Faculty Publications

The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.

Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu Tekalign, Margo Levine

Mathematics Faculty Publications

The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.

Exact Controllability Of A Rayleigh Beam With A Single Boundary Control, Ahmet Ozkan Ozer, Scott Hansen

Mathematics Faculty Publications

No abstract provided.

Inter-Colony Comparison Of Diving Behavior Of An Arctic Top Predator: Implications For Warming In The Greenland Sea, Nina J. Karnovsky, Zachary W. Brown '07, Jorg Welcker, Ann M.A. Harding, Wojciech Walkusz, André Cavalcanti, Johanna S. Hardin, Alexander Kitaysky, Geir Gabrielsen, David Grémillet

Pomona Faculty Publications and Research

The goal of this study was to assess how diverse oceanographic conditions and prey communities affect the foraging behavior of little auks Alle alle. The Greenland Sea is characterized by 3 distinct water masses: (1) the East Greenland Current (EGC), which carries Arctic waters southward; (2) the Sørkapp Current (SC), which originates in the Arctic Ocean but flows north along the west coast of Spitsbergen; and (3) the West Spitsbergen Current (WSC), which carries warm Atlantic-derived water north. Each of these 3 water masses is characterized by a distinct mesozooplankton community. Little auks breeding adjacent to the EGC have …

Operation Comics: The Story Continues, Bruce Kessler, Janet Tassell, Tressa Tullis

Mathematics Faculty Publications

During the 2008-2009 academic year, the author K. wrote three issues of Operation Comics, a comic book with embedded mathematics content appropriate for 4th through 6th grade students. Several printed comics were placed in Cumberland Trace Elementary in the Warren County School System in Bowling Green, Kentucky, US. The author Ta. was enlisted to measure the impact of the comics on the attitudes and motivation of the students using the comics. A preliminary report was given by K. at the 2009 Bridges Banff Conference, and the written report appeared in the proceedings. Since then, data has been collected on the …

Comparative Analysis Of Expected Utility Theory Versus Prospect Theory And Critique Of Their Recent Developments, Sassan Sadeghi

Theses Digitization Project

This study is an investigation of the decision making theories, their developments, and especially, their applications. After locating the two rivals, the Expected Utility Theory (EUT) and the Prospect Theory (PT), within the general context of decision making situations, it compares their main features and examines the PT extensions.