Physical Sciences and Mathematics Commons^™

Combination Of Irreversible Electroporation And Clostridium Novyi-Nt Bacterial Therapy For Colorectal Liver Metastasis, Zigeng Zhang, Guangbo Yu, Qiaoming Hou, Farideh Amirrad, Sha Webster, Surya M. Nauli, Jianhua Yu, Vahid Yaghmai, Aydin Eresen, Zhuoli Zhang

Pharmacy Faculty Articles and Research

Colorectal liver metastasis (CRLM) poses a significant challenge in oncology due to its high incidence and poor prognosis in unresectable cases. Current treatments, including surgical resection, systemic chemotherapy, and liver-directed therapies, often fail to effectively target hypoxic tumor regions, which are inherently more resistant to these interventions. This review examines the potential of a novel therapeutic strategy combining irreversible electroporation (IRE) ablation and Clostridium novyi-nontoxic (C. novyi-NT) bacterial therapy. IRE is a non-thermal tumor ablation technique that uses high-voltage electric pulses to create permanent nanopores in cell membranes, leading to cell death while preserving surrounding structures, and …

Investigating The Impact Of Agent Openness On Planning In Multi-Agent Systems, Bala Subramanyam Duggirala

School of Computing: Dissertations, Theses, and Student Research

Multi-agent systems (MAS) possess significant potential for modeling real-world scenarios requiring coordinated actions (like wildfire fighting or ridesharing) among autonomous entities or agents (e.g., wildfire fighting agents) in complex, dynamic environments. Effective decision-theoretic planning (where each agent must carefully consider both the immediate and the future situations or states, and coordinate with the other agents (neighbors) to evaluate what needs to be done at present) within MAS, especially multiagent planning, where the planning agent directly models its neighbors in order to estimate their optimal actions, is critical, yet challenged by factors like partial observability, openness, and diverse agent types with …

Thinking On Simulation Science And Engineering In The Era Of Artificial Intelligence, Wenhui Fan, Yuan Jiang

Journal of System Simulation

Abstract: With the rapid advancement of artificial intelligence and computing technologies, simulation technologies have leapfrogged, propelling the discipline of simulation toward greater maturity. Research progress in computer simulation technologies both in China and abroad was reviewed, and the definition and connotation of simulation were clarified. It was proposed that the Chinese terms "仿真" "仿效"and " 模拟" be unified under a single term " 仿真" with corresponding "Simulation" "Emulation" and "Analog" in English translated uniformly as "Simulation". Simulation science and engineering discipline was delineated, which was grounded in three core theoretical foundations: analogical theory,computational theory, and model validation theory. The first-level …

Stranger Disputes: When Artificial Intelligence Turns Arbitration Upside Down, Imre Stephen Szalai

Pepperdine Dispute Resolution Law Journal

Arbitration agreements are everywhere in the United States. These agreements already block access to courts in a troubling manner, and pursuant to these agreements, parties must resolve their disputes before a private, human arbitrator with broad, virtually unreviewable powers. However, with the growth of AI, companies could easily redraft their contracts to require arbitration before non-human bots or AI arbitrators instead of a human arbitrator. Based on the history, values, policy, and text of the Federal Arbitration Act (FAA), this Article concludes that the FAA would govern and support the use of an AI arbitrator. As a result, a pre-dispute …

Digital Forensics And Ai: Artifact Analysis And Using Ai In The Forensics Domain, Clinton Joel Walker

LSU Doctoral Dissertations

Digital Forensics (DF) is a field of forensic science focusing on the acquisition, authentication, and analysis of digital evidence while maintaining integrity of that data. DF analysts use forensic tools to parse large volumes of data for investigations and depend on them for identification of pertinent digital evidence in vast amounts of data. Keeping up with innovations and ever-expanding data volumes is a constant challenge for these investigators. The prevalence of Artificial Intelligence (AI) in everyday computing is rapidly expanding, with the use of Machine Learning (ML) and Large Language Models (LLM)s becoming increasingly commonplace. Innovations in technology bring new …

Research And Education In Robotics: A Comprehensive Review, Trends, Challenges, And Future Directions, Mutaz Ryalat, Natheer Almtireen, Ghaith Al-Refai, Hisham Elmoaqet, Nathir Rawashdeh

Michigan Tech Publications

Robotics has emerged as a transformative discipline at the intersection of the engineering, computer science, and cognitive sciences. This state-of-the-art review explores the current trends, methodologies, and challenges in both robotics research and education. This paper presents a comprehensive review of the evolution of robotics, tracing its development from early automation to intelligent, autonomous systems. Key enabling technologies, such as Artificial Intelligence (AI), soft robotics, the Internet of Things (IoT), and swarm intelligence, are examined along with real-world applications in healthcare, manufacturing, agriculture, and sustainable smart cities. A central focus is placed on robotics education, where hands-on, interdisciplinary learning is …

"Chatgpt Told Me To Say It": Ai Chatbots And Class Participation Apprehension In University Students, Daisuke Akiba

Publications and Research

The growing prevalence of AI chatbots in everyday life has prompted educators to explore their potential applications in promoting student success, including support for classroom engagement and communication. This exploratory study emerged from semester-long observations of class participation apprehensions in an introductory educational psychology course, examining how chatbots might scaffold students toward active and independent classroom contribution. Four students experiencing situational participation anxiety voluntarily participated in a pilot intervention using AI chatbots as virtual peer partners. Following comprehensive training in AI use and prompt design given to the entire class, participants employed systematic consultation frameworks for managing classroom discourse trepidations. …

Type-2 Neutrosophic Numbers For Artificial Intelligence Software Choice For Cybersecurity Testing, O.M. Akash, We’Am Adel Talafha, Mamdouh Gomaa

Neutrosophic Systems with Applications

The choice of artificial intelligence (AI) software for cybersecurity testing is a multi-criteria decision-making approach (MCDM) due to it including different criteria. Evaluation decision making problems include uncertainty and vague information. So, the neutrosophic set is used in this study to overcome this uncertainty and vague information. It has three functions such as truth, indeterminacy, and falsity functions. Type-2 neutrosophic numbers is a type of neutrosophic set that includes nine membership functions. This study uses the average method of computing the criteria weights. The CoCoSo method is used to rank alternatives. Six experts and decision makers created the decision makers …

Bridging Classical Rhetoric And Ai: A Systematic Framework For Developing Authorial Voice Through Large Language Models, Daniel Plate

Theses

This project addresses critical gaps in AI-assisted writing by developing the first systematic framework that integrates classical rhetorical principles with modern large language model capabilities for authorial voice development. The primary focus is on creating reliable methods for stylistic control through strategic AI collaboration rather than ad hoc prompting approaches. The project develops a comprehensive coding system for analyzing prose style, creates ten distinct authorial personas, and establishes a dual curation methodology that structures both stylistic analysis and content preparation. Implementation through the AI Writing Guide website provides practical tools including prompt templates, annotated examples, and instructional materials that demonstrate …

Analysis Of Vision Transformers And Domain Adaptation In Long-Range Facial Recognition, Zachary Michael Swanson

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Atmospheric turbulence presents a significant barrier to long-range facial recognition, introducing severe geometric distortions and blur that degrade image quality. This thesis investigates deep learning approaches for mitigating these effects, with a focus on transformer based architectures and domain adaptation strategies.

An in-depth benchmarking study was performed using convolutional neural networks (CNNs) and vision transformers (ViTs) on the Husker BRIAR Research Collection from up to 500m (HBRC-500) face dataset. The results demonstrated that vision transformers, particularly hierarchical vision transformers like the shifted-window (Swin) transformer, outperform CNN-based models at long distances due to their ability to model global spatial relationships and …

Process-Grounded Knowledge-Infused Learning And Decision Making, Kaushik Roy

Theses and Dissertations

This dissertation introduces process-grounded knowledge-infused learning and reasoning, a novel framework for integrating domain-expertise-based process knowledge into the learning and reasoning mechanisms of artificial intelligence systems. This approach is designed to produce controlled, transparent, and reliable predictions in critical tasks such as medical diagnosis and recommendation. By focusing on the case study of mental illness diagnosis and recommendation—where decision-making must be grounded in processes such as disorder-specific diagnostic criteria—this work demonstrates methods to embed structured decision-making directly into the system architecture during both training and inference. This integration facilitates end-to-end training and reasoning while ensuring that outputs strictly adhere to …

Forging The Future, Kenneth Benoit

Asian Management Insights

How AI is rewriting the rules of knowledge, expertise, and practice.

Strategy And Stewardship In An Uncertain World, Havovi Joshi

Asian Management Insights

This issue, as we continue to celebrate Singapore Management University’s (SMU) 25th anniversary, we explore leadership in higher education, the rise of artificial intelligence (AI), ethical stewardship, and other challenges, highlighting how they intersect in our increasingly complex, fast-changing world.

Alibaba: Building Advanced Intellectual Property Governance For E-Commerce Marketplaces, Liang Chen, Sin Mei Cheah, Can Huang, Guoqiao Liu

Asian Management Insights

How the global e-commerce powerhouse harnessed artificial intelligence (AI) to balance innovation and intellectual property (IP) rights protection.

Potential And Pitfalls Of Romantic Artificial Intelligence (Ai) Companions: A Systematic Review, Qi Hui Jerlyn Ho, Meilan Hu, Tracy Xi Chen, Andree Hartanto

Research Collection School of Social Sciences

As Artificial Intelligence (AI) becomes more integrated into daily life, individuals have increasingly turned to AIdriven systems for emotional support, companionship, and even romantic relationships. These relationships can be both beneficial and detrimental. Given the need for a comprehensive understanding of this phenomenon, this systematic review uses Sternberg’s Triangular Theory of Love to provide a holistic summary of its key potentials and pitfalls. A total of 23 articles were identified from the following databases: EBSCOhost ERIC, EBSCOhost PsycInfo, PubMed, Scopus, and Web of Science. Results highlighted the key potentials of being in a romantic relationship with AI companions as: the …

Computerized Diagnostic Decision Support Systems-Isabel Pro Versus Chatgpt-4 Part Ii, Joe M Bridges, Xiaoqian Jiang, Michael Ige, Oluwatoniloba Toyobo

Faculty, Staff and Student Publications

Objective: Does a Tree-of-Thought prompt and reconsideration of Isabel Pro's differential improve ChatGPT-4's accuracy; does increasing expert panel size improve ChatGPT-4's accuracy; does ChatGPT-4 produce consistent outputs in sequential requests; what is the frequency of fabricated references?

Materials and methods: Isabel Pro, a computerized diagnostic decision support system, and ChatGPT-4, a large language model. Using 201 cases from the New England Journal of Medicine, each system produced a differential diagnosis ranked by likelihood. Statistics were Mean Reciprocal Rank, Recall at Rank, Average Rank, Number of Correct Diagnoses, and Rank Improvement. For reproducibility, the study compared the initial expert panel run …

Digital Resurrection Of Thonis-Heracleion: Technological Advances In Underwater Archaeology And A Speculative Ai-Driven Reconstruction Methodology, James Hutson, Passent Chahine

Faculty Scholarship

This article synthesizes past archaeological research on the submerged Egyptian city of Thonis-Heracleion, critically reviewing excavations and technological interventions deployed since its rediscovery by Franck Goddio and the IEASM team. Situated approximately 10 meters beneath Aboukir Bay near Alexandria, the city represents a significant nexus of Greek and Egyptian cultural heritage, vividly documented in classical sources such as Herodotus and Strabo. Prior excavations have recovered temple complexes, colossal statues, ritual artifacts, and an extensive array of ancient shipwrecks, mapping only a fraction of the extensive site. These investigations utilized pioneering geophysical methods, including multibeam sonar, side-scan sonar, and photogrammetry, establishing …

Artificial Intelligence Use In Medical Education: Best Practices And Future Directions, Rasheed A. M. Thompson, Yash B. Shah, Francisco Aguirre, Courtney Stewart, Costas D. Lallas, Mihir S. Shah

Department of Urology Faculty Papers

PURPOSEOF REVIEW: This review examines the various ways artificial intelligence (AI) has been utilized in medical education (MedEd)and presents ideas that will ethically and effectively leverage AI in enhancing the learning experience of medical trainees.

RECENT FINDINGS: AI has improved accessibility to learning material in a manner that engages the wider population. It has utility as a reference tool and can assist academic writing by generating outlines, summaries and identifying relevant reference articles. As AI is increasingly integrated into MedEd and practice, its regulation should become a priority to prevent drawbacks to the education of trainees. By involving physicians in …

Selected Artificial Intelligence Provisions In U.S. Fiscal Year 2025 National Defense Authorization Act, Bert Chapman

Libraries Faculty and Staff Presentations

The 2025 Fiscal Year National Defense Authorization Act contains multiple provisions relating to artificial intelligence (AI). These congressionally mandated provisions direct various sections of the Department of Defense (DOD) and individual U.S. armed service branches to execute congressional intent for AI policymaking. Examples of such intent include identifying and planning DOD's AI workforce, demonstrating AI biotechnology applications for national security, improving the human usability of AI systems, and establishing an AI security center. This presentation will note that reports on these initiatives must be prepared for relevant congressional oversight committees, and, in many cases, are in many cases, publicly released …

Robotic Rhythm: A Contemporary Look At Ai-Driven Editing Tools’ Efficacy In Understanding And Replicating Creative Rhythm Editing Techniques., Alexander Selby-Lara, Charles Howard

Honors Thesis

It is undeniable that artificial intelligence (AI) has made its way into the film world. From AI-generated imagery and sound design in two 2025 Oscar nominees — The Brutalist and Emilia Pérez (Pulver) — to weekly updates and monthly beta releases of existing and new generative image and video models, AI-driven filmmaking tools are here to stay. But what does this mean for the post-production workflow? Much like camera development, editing technology has come a long way from flatbed film editors to Adobe Premiere Pro v. 25.0. Yet, despite each technological leap from system to system, the delicate task of …

Voice Interaction With Conversational Ai Could Facilitate Thoughtful Reflection And Substantive Revision In Writing, Jiho Kim, Philippe Laban, Xiang 'Anthony' Chen, Kenneth C. Arnold

University Faculty Publications and Creative Works

Writing well requires not only expressing ideas but also refining them through revision, a process facilitated by reflection. Prior research suggests that feedback delivered through dialogues, such as those in writing center tutoring sessions, can help writers reflect more thoughtfully on their work compared to static feedback. Recent advancements in multi-modal large language models (LLMs) now offer new possibilities for supporting interactive and expressive voice-based reflection in writing. In particular, we propose that LLM-generated static feedback can be repurposed as conversation starters, allowing writers to seek clarification, request examples, and ask follow-up questions, thereby fostering deeper reflection on their writing. …

Interaction-Required Suggestions For Control, Ownership, And Awareness In Human-Ai Co-Writing, Kenneth C. Arnold, Jiho Kim, Jason G. Chew, Jooha Yoo, Juyeong Kim, Ray Flanagan, Heonjae Kwon

University Faculty Publications and Creative Works

This paper explores interaction designs for gen-
erative AI interfaces that necessitate human in-
volvement throughout the generation process.
We argue that such interfaces can promote
cognitive engagement, agency, and thoughtful
decision-making. Through a case study in text
revision, we present and analyze two interac-
tion techniques: (1) using a predictive-text in-
teraction to type the assistant’s response to a
revision request, and (2) highlighting potential
edit opportunities in a document. Our imple-
mentations demonstrate how these approaches
reveal the landscape of writing possibilities and
enable fine-grained control. We discuss impli-
cations for human-AI writing partnerships and
future interaction design …

How Will Artificial Intelligence Impact The Roles, Skills, And Design Processes Of Ux Professionals In The Next 5 Years?, Olivia Behan

Informatics

Artificial intelligence (AI) is changing the way we think about user experience (UX) design. This thesis explores how AI could impact the roles, skills, and design processes of UX professionals over the next five years. The research conducted consists of a mixed-methods approach, combining an online survey administered through Qualtrics to 50 survey respondents and a case study, which included individually interviewing 3 UX professionals over Zoom, to gather data and personal insights. The results show that while AI has the power and potential to make some parts of UX work faster, like research analysis, prototyping, and automating redundant tasks, …

Ai Model For Predicting Asthma Prognosis In Children, Elham Sagheb, Chung-Il Wi, Katherine S King, Bhavani Singh Agnikula Kshatriya, Euijung Ryu, Hongfang Liu, Miguel A Park, Hee Yun Seol, Shauna M Overgaard, Deepak K Sharma, Young J Juhn, Sunghwan Sohn

Faculty, Staff and Student Publications

BACKGROUND: Childhood asthma often continues into adulthood, but some children experience remission. Utilizing electronic health records (EHRs) to predict asthma prognosis can aid health care providers and patients in developing effective prioritized care plans.

OBJECTIVE: We aimed to develop artificial intelligence (AI) models using various clinical variables extracted from EHRs to predict childhood asthma prognosis (remission vs no remission) in different age groups.

METHODS: We developed AI models utilizing patients' EHRs during the first 6, 9, or 12 years of their lives to predict their asthma prognosis status at ages 6 to 9, 9 to 12, or 12 to 15 …

Phoneme Recognition For Pronunciation Improvement, Matthew Heywood

Theses/Capstones/Creative Projects

This project aims to improve English pronunciation by investigating speech errors and developing a tool to provide precise feedback. The study focuses on creating a new pronunciation tool that offers localized feedback, identifies specific errors, and suggests corrective measures. By addressing the shortcomings of current methods, this research seeks to enhance pronunciation refinement.

Utilizing cutting-edge technology, the tool leverages speech-to-phoneme AI models and modified lazy string matching algorithms to compare the user's spoken input with the intended pronunciation. This allows for a detailed analysis of discrepancies, providing users actionable insights into their phonetic errors. The speech-to-phoneme AI models mark a …

Enhancing Product Image Classification: Utilizing Machine Learning Models For Retail Applications, Avery A. Thompson

Data Science Undergraduate Honors Theses

The expansion of e-commerce has continued at a blinding pace since the COVID-19 pandemic, and retailers are constantly looking for new ways to retain customers. Ensuring that diverse and well-classified images are on product pages has been a paramount method for retailers to ensure retention as they increase product engagement and sales and enhance user experience. Managing and labeling these vast catalogs of images by hand is becoming increasingly infeasible, so some online retailers have started to turn to automated classification models to assist them. Accuracy in these classification models is integral, as a good image classification model can improve …

Simulating Chill: Exploring The Cognitive And Therapeutic Potential Of Cold Vr Environments, Jessica Turner, Piper Hutson, James Hutson

Faculty Scholarship

This study investigates the cognitive and therapeutic potential of immersive virtual reality (VR) environments designed to simulate cold conditions. Through the engagement of participants through multisensory stimuli—including vivid visual representations of the Athabasca Glacier, auditory effects of icy winds, and corresponding haptic feedback—the research evaluates neurological and physiological responses associated with attention, emotional regulation, and stress modulation. Participants experienced virtual scenarios featuring icy winds and snow, activating specific neurological pathways involving the occipital lobe, primary visual cortex, superior colliculus, and insula, thus reinforcing sensory integration. Through predictive coding, the anterior insula and hypothalamus were engaged, prompting thermoregulatory simulations and subconscious …

1785 Parisian Salon Project: New Methods And Practical Innovations In Digital Heritage Reconstruction, James Hutson, Charles O'Brien, Wesley Wolfe, Kayla Kraff, Trent Olsen

Faculty Scholarship

The 1785 Salon Unreal Engine Reconstruction Project represents a significant advance in digital heritage and immersive art historical research by combining generative AI-based asset creation, modular user experience (UX) design, and historically informed workflows. During the Spring 2025 phase, the project achieved major milestones, including the successful development of a replicable pipeline for transforming 2D reference images into period-accurate 3D sculpture models using generative AI and digital sculpting tools. Simultaneously, a robust and adaptable Inspection System was engineered within Unreal Engine, offering granular interaction controls, bilingual (English/French) content integration, dynamic metadata display, and enhanced accessibility. These innovations collectively enabled historically …

Exploring The Biasing Effects Of Gender On Personality Disorder Diagnoses Formulated By Artificial Intelligence, Zoe Colclough

Student Theses

Gender bias is prevalent in personality disorder assessments, and while artificial intelligence has been posited as a solution to improve diagnostic objectivity and accuracy, the potential for such technologies to propagate human gender bias in mental health contexts remains underexplored. This study investigated the influences of gender bias on the diagnostic performance of ChatGPT-4o for personality disorders using three factorial research designs, which involved experimentally manipulating patient gender in a combined sample of 360 vignettes and case studies. Vignettes were synthesized through a novel artificial intelligence-assisted methodology established for this research, and case studies were identified from the literature. Significant …

Generalizable Skill Learning In Robotic Agents Using Transformer Models, Erik Enriquez

Theses and Dissertations

This work explores the application of Transformer models to robotic skill learning, aiming to enhance generalization across various physical tasks and environments with continuous control. Despite their success in other domains, our experiments reveal that the utility of Transformers in robotics heavily depends on pretraining strategies. Specifically, Transformers pretrained on reinforcement learning tasks generalized effectively, while those trained with task-agnostic masking strategies did not. These findings challenge assumptions about the universality of Transformer-based methods and underscore the importance of domain-aligned pretraining for developing versatile robotic agents.