Physical Sciences and Mathematics Commons^™

Introduction: Metrics, Modeling And Simulation For Cyber Physical Systems, Barry Ezell, Luanne Burns

VMASC Publications

[Introduction] In recent years, there has been a massive increase in cyber crime. Cyber breeches have become ubiquitous. The US government is attempting to adapt through legislation and policy. For instance, business in the defense industrial base must be in compliance of NIST 80-71 by 31 December 2017. Insurance companies as well are beginning to build actuaries on cyber risk. Along with NIST, there are many cyber frameworks that exist, each with their own following. Recently, companies have sought mapping from one framework to another but this is imperfect solution because some frameworks are exclusively technical control measures with very …

Research Agenda In Developing Core Reference Ontology For Human Intelligence/Machine-Intelligence Electronic Medical Records System, Ziniya Zahedi, Teddy Steven Cotter

Engineering Management & Systems Engineering Faculty Publications

Beginning around 1990, efforts were initiated in the medical profession by the U.S. government to transition from paper based medical records to electronic medical records (EMR). By the late 1990s, EMR implementation had already encountered multiple barriers and failures. Then President Bush set forth the goal of implementing electronic health records (EHRs), nationwide within ten years. Again, progress toward EMR implementation was not realized. President Obama put new emphasis on promoting EMR and health care technology. The renewed emphasis did not overcome many of the original problems and induced new failures. Retrospective analyses suggest that failures were induced because programmers …

An Attribute Agreement Method For Hfacs Inter-Rater Reliability Assessment, Teddy Steven Cotter, Veysel Yesilbas

Engineering Management & Systems Engineering Faculty Publications

Inter-rater reliability can be regarded as the degree of agreement among raters on a given item or a circumstance. Multiple approaches have been taken to estimate and improve inter-rater reliability of the United States Department of Defense Human Factors Analysis and Classification System used by trained accident investigators. In this study, three trained instructor pilots used the DoD-HFACS to classify 347 U.S. Air Force Accident Investigation Board (AIB) Class-A reports between the years of 2000 and 2013. The overall method consisted of four steps: (1) train on HFACS definitions, (2) verify rating reliability, (3) rate HFACS reports, and (4) random …

Economics-Based Risk Management Of Distributed Denial Of Service Attacks: A Distance Learning Case Study, Omer Keskin, Unal Tatar, Omer Poyraz, Ariel Pinto, Adrian Gheorghe

Engineering Management & Systems Engineering Faculty Publications

Managing risk of cyber systems is still on the top of the agendas of Chief Information Security Officers (CISO). Investment in cybersecurity is continuously rising. Efficiency and effectiveness of cybersecurity investments are under scrutiny by boards of the companies. The primary method of decision making on cybersecurity adopts a risk-informed approach. Qualitative methods bring a notion of risk. However, particularly for strategic level decisions, more quantitative methods that can calculate the risk and impact in monetary values are required. In this study, a model is built to calculate the economic value of business interruption during a Distributed Denial-of-Service (DDoS) attack …

Deep Convolutional Neural Networks Enable Discrimination Of Heterogeneous Digital Pathology Images, Pegah Khosravi, Ehsan Kazemi, Marcin Imielinski, Olivier Elemento, Iman Hajirasouliha

Publications and Research

Pathological evaluation of tumor tissue is pivotal for diagnosis in cancer patients and automated image analysis approaches have great potential to increase precision of diagnosis and help reduce human error.

In this study, we utilize several computational methods based on convolutional neural networks (CNN) and build a stand-alone pipeline to effectively classify different histopathology images across different types of cancer.

In particular, we demonstrate the utility of our pipeline to discriminate between two subtypes of lung cancer, four biomarkers of bladder cancer, and five biomarkers of breast cancer. In addition, we apply our pipeline to discriminate among four immunohistochemistry …

Report On The Condition Trend Of The Western Australian Pastoral Resource Base 2017, Andrew Watson, Philip Thomas

Natural resources published reports

This report has been prepared to satisfy the Commissioner for Soil and Land Conservation’s obligation under section 137 (2) of the Land Administration Act 1997 to report on the current condition of land under pastoral lease in Western Australia.

Pastoral leases for livestock grazing cover 40% of the Western Australian rangelands (about 860 000 square kilometres). Data in this report is presented at the land conservation district (LCD) scale.

Rangeland condition is determined with regard to the presence of perennial pasture species that are productive and highly palatable to livestock, and soil condition. Although assessing rangeland condition by on-ground assessment …

Comparing Source Rock Maturity With Pore Size Distribution And Fluid Saturation In The Bakken-Three Forks Petroleum System, Williston Basin, North Dakota, Adedoyin Suleman Adeyilola

Theses and Dissertations

With the continuous demand for fossil fuel and advancement in technology, the unconventional petroleum resources have come into limelight. The Devonian Three Forks Formation consisting of carbonate and clastic sediments is an unconventional oil accumulation

containing about 3.73 billion barrels of technically recoverable oil. However, understanding rock properties of the various lithofacies and fluid saturation is still challenging.

The petroleum prospectivity was evaluated by integrating organic maturity and hydrocarbon generation with porosity distribution and fluid saturation in the Ambrose field and adjacent fields. The organic maturity was done with a programmed pyrolysis analysis (Source

Rock Analyzer) using samples taken at …

Nonlinear Coupled Effects In Nanomaterials, Sia Bhowmick

Theses and Dissertations (Comprehensive)

Materials at the nanoscale have different chemical, structural, and optoelectrical properties compared to their bulk counterparts. As a result, such materials, called nanomaterials, exhibit observable differences in certain physical phenomena. One such resulting phenomenon called the piezoelectric effect has played a crucial role in miniature self-powering electronic devices called nanogenerators which are fabricated by using nanostructures, such as nanowires, nanorods, and nanofilms. These devices are capable of harvesting electrical energy by inducing mechanical strain on the individual nanostructures. Electrical energy created in this manner does not have environmental limitations. In this thesis, important coupled effects, such as the nonlinear piezoelectric …

Abelian Subalgebras Of Maximal Dimension In Euclidean Lie Algebras, Mark Curro

Theses and Dissertations (Comprehensive)

In this paper we define, discuss and prove the uniqueness of the abelian subalgebra of maximal dimension of the Euclidean Lie algebra. We also construct a family of maximal abelian subalgebras and prove that they are maximal.

Permafrost Thaw-Induced Forest To Wetland Conversion: Potential Impacts On Snowmelt And Basin Runoff In Northwestern Canada, Emily Haughton

Theses and Dissertations (Comprehensive)

In the discontinuous permafrost zone of northwestern Canada, snow covers the ground surface for over half the year, thus snowmelt constitutes a primary source of ecosystem moisture supply and strongly influences stream hydrographs. The peat landscapes along the southern limit of discontinuous permafrost are dominated by forested permafrost plateaus (“forest”), and treeless, permafrost-free wetlands (“wetland”). Permafrost-thaw induced transformation of this landscape has changed water flow and storage processes and therefore introduced new uncertainties on the region’s water futures. Here, I a) characterize forest and wetland water storage and flow from snowmelt, and b) evaluate how permafrost thaw-induced wetland expansion at …

Spatial And Temporal Variability Of The Snow Environment In The Western Canadian Arctic, Philip Mann

Theses and Dissertations (Comprehensive)

Snow cover in the Western Canadian Arctic is a significant input to the hydrological mass balance, it produces shelter and habitat for animals and humans, and supports interactions with vegetation and climate. The Arctic-tundra snow cover is greatly impacted by wind erosion, redistribution and deposition of snow during high wind events over the winter months. As a result, the end of winter snow cover is characterised by significant small-scale (on the order of a few meters) spatial variations in snow cover depth, density, and thus snow water equivalent (SWE), and runoff. Future climate related changes to snow cover depth and …

The Role Of Channel Fens In Permafrost Degradation Induced Changes In Peatland Discharge At Scotty Creek, Nt, Lindsay Elena Stone

Theses and Dissertations (Comprehensive)

Permafrost degradation in the peat-rich southern fringe of the discontinuous permafrost zone is producing substantial changes to land cover with concomitant expansion of permafrost-free wetlands (bogs and fens) and shrinkage of forest supported by permafrost peat plateaus. Predicting discharge from headwater basins in this region depends on understanding and numerically representing the interactions between storage and discharge within and between the major land cover types, and how these interactions are changing. To better understand the implications of land cover change on wetland discharge, the hydrological behaviour of a channel fen in the headwaters of Scotty Creek, Northwest Territories, Canada, dominated …

Landscape Scale Spectral-Temporal Modelling Of Bamboo-Dominated Forest Succession Within The Atlantic Forest Of Southern Brazil, Clara Greig

Theses and Dissertations (Comprehensive)

Tropical and subtropical ecosystems have become vulnerable to biological invasion (i.e., bamboo) due to human induced forest fragmentation. Bamboo ecological processes have been found to impede forest development, resulting in a state of arrested succession, which has been found to significantly reduce biodiversity, thus contributing to biotic homogenization. In this study we use a semi-empirical approach to develop a community-level spatially explicit ecological process model (hybrid model) using a time-series of Landsat imagery to describe single-landscape scale ecological processes of a pervasive bamboo species (Merostachys skvortzovii) found throughout the Araucaria forest, a critically threatened subtype of Atlantic forest …

Spatial Modelling And Wildlife Health Surveillance: A Case Study Of White Nose Syndrome In Ontario, Lauren Yee

Theses and Dissertations (Comprehensive)

Wildlife data is often limited by survey effort, small sample sizes, and spatial biases associated with collection and missing data. These factors can create unique challenges from a surveillance perspective when trying to extract spatial patterns of habitat suitability and disease distributions for conservation and management purposes. This thesis examined data quality from a wildlife health database in the context of spatial analysis of wildlife disease. Spatial analysis of the data to predict habitat suitability of bats and white nose syndrome afflicted bats was examined by using the MaxEnt modelling method. Methods to reduce spatial bias were examined and specific …

The Effects Of Fire On Snow Accumulation, Snowmelt And Ground Thaw On A Peat Plateau In Subarctic Canada, Elyse Mathieu

Theses and Dissertations (Comprehensive)

During the past century, the highest rates of warming have occurred at latitudes above 60^oN, where air temperatures have risen at twice the rate of other regions. In northwestern Canada, this warming has coincided with an increase in the frequency, size and severity of wildfires. The influence of such fires on the trajectory of on-going permafrost thaw is not well understood. As a consequence, the combined impacts of climate warming induced permafrost thaw and possible feedbacks arising from wildfires cannot be properly assessed. This study examines the impact of a 2.7 ha low-severity wildfire (July 2014) on water …

The Effect Of Oxidation, Thionation, And Dimerization On The Self-Assembly And Photophysical Properties Of Novel Discotic Materials, Katie M. Psutka

Theses and Dissertations (Comprehensive)

This thesis aims to increase understanding of the relationship between molecular structure and liquid crystalline temperature range by exploring the effects of oxidation, thionation, and dimerization on the self-assembly and properties of novel discotic materials. First, two alkoxy-substituted dibenzanthracenequinones were prepared by oxidation of the corresponding dibenzanthracenes. The quinone induced a liquid crystalline phase in the hexaalkoxy dibenzanthracene derivative, but not in the tetralkoxy derivative. However, both of the resulting materials were un-reactive to any further synthetic modifications that could be used to improve their properties. In comparison, two heteroaromatic dithienoanthracenedicarboximides were successfully prepared, although the addition of the thiophene …

Synthesis, Properties, And Solid-State Structures Of A Series Of 6,13-Dicyanoheteropentacene Analogues: Towards New Liquid Crystalline Materials, L Hiscock, Kenneth E. Maly, Louise N. Dawe

Theses and Dissertations (Comprehensive)

The focus of this thesis is the synthesis of novel heterocyclic pentacene analogs and the investigation of their self-organization for the development of new materials for organic electronics. The thesis consists of two interrelated projects: the first being development of an improved synthesis of a series of liquid crystalline dicyanotetraoxapentacenes (DCTOPs) while the second entails the exploratory synthesis of several novel dicyanoheteropentacene analogues and a preliminary investigation of their photophysical properties and solid-state structures. Both of these projects centre around the use of nucleophilic aromatic substitution reactions on tetrafluoroterephthalonitrile.

Soluble, tetrakis(bis(alkoxy)phenyl)-substituted DCTOPs were originally synthesised via a short synthesis complicated …

Near-Surface Permafrost Ground Ice Characteristics And Ecological And Physical Drivers Of Transient Layer Ice Content In Discontinuous Permafrost, Jason Paul

Theses and Dissertations (Comprehensive)

Accelerated climate warming in northern regions is causing permafrost degradation, leading to the reduction of the areal extent of permafrost. Permafrost is the foundation for many northern ecosystems and communities, so its thaw can have important ecological and societal consequences. Thaw of ice-rich permafrost can cause subsidence of the ground surface proportional to excess ice content. Terrain settlement can cause ponding or damage to infrastructure. Following a surface disturbance that removes much of the vegetation cover, a shift in the ground thermal regime can cause an increase in active layer thickness and rapid thaw of the top portion of permafrost. …

Within-Fire Patchiness Associated With Prescribed Burning In The Northern Jarrah Forests Of Western Australia, Zigourney Nielsen

Theses: Doctorates and Masters

There is growing understanding of the importance of landscape mosaics and heterogeneity for biodiversity outcomes in Western Australia. However, there is limited information on the patchiness (spatial configuration of unburnt and burnt patches which occur at a range of spatial scales) within the perimeter of a single prescribed burn. Of particular concern is the idea that prescribed burning operations, carried out under very restricted weather and environmental conditions, can lead to structural and floristic homogenization of the area within a burn perimeter. This may be evident as reduced post-fire vegetation patchiness. Western Australian Jarrah (Eucalyptus marginata) forests are managed to …

An Investigation Into Trust And Security In The Mandatory And Imposed Use Of Financial Icts Upon Older People, David Michael Cook

Theses: Doctorates and Masters

Care needs to be taken to reduce the number of people who are fearful and mistrustful of using ICT where that usage is forced upon them without choice or alternative. The growing incidence of mandatory and imposed online systems can result in confusion, misuse, fear, and rejection by people with only rudimentary ICT skills. A cohort where a high percentage of such people occur is older people, defined in this study as people over the age of 60 Examples of compulsory ICT interactions include some banks limiting bank statement access through online rather than paper-based options. Other examples include the …

A Framework For Development Of Android Mobile Electronic Prescription Transfer Applications In Compliance With Security Requirements Mandated By The Australian Healthcare Industry, Kyaw Kyaw Htat

Theses: Doctorates and Masters

This thesis investigates mobile electronic transfer of prescription (ETP) in compliance with the security requirements mandated by the Australian healthcare industry and proposes a framework for the development of an Android mobile electronic prescription transfer application. Furthermore, and based upon the findings and knowledge from constructing this framework, another framework is also derived for assessing Android mobile ETP applications for their security compliance.

The centralised exchange model-based ETP solution currently used in the Australian healthcare industry is an expensive solution for on-going use. With challenges such as an aging population and the rising burden of chronic disease, the cost of …

Development, Manufacture And Application Of A Solid-State Ph Sensor Using Ruthenium Oxide, Wade Lonsdale

Theses: Doctorates and Masters

The measurement of pH is undertaken frequently in numerous settings for many applications. The common glass pH probe is almost ideal for measuring pH, and as such, it is used almost ubiquitously. However, glass is not ideal for all applications due to its relatively large size, fragility, need for recalibration and wet-storage. Therefore, much research has been undertaken on the use of metal oxides as an alternative for the measurement of pH.

Here, a solid-state potentiometric pH sensor is developed using ruthenium metal oxide (RuO2). Initially, pH sensitive RuO2 electrodes were prepared by deposition with radio frequency magnetron sputtering (RFMS) …

The Value Of Animal Behaviour As A Bio-Indicator Of Restoration Quality, Floyd Holmes

Theses: Doctorates and Masters

Woodland restoration is a complex endeavour, and restoration ecology as a scientific discipline requires constant re-assessments and adjustments if it is to improve outcomes and better provide for biodiversity. The promise of effective restoration is often used to justify destructive processes that affect many of the world’s ecosystems. It is therefore imperative that those promises can be met, which comes down to restoration ecologists’ and land managers’ capacity to predict and facilitate desirable ecological changes in a timely and socio-economically responsible manner. As perspectives have changed, and knowledge has been gained over the past few decades there have been several …

Automated Optical Mark Recognition Scoring System For Multiple-Choice Questions, Murtadha Alomran

Theses: Doctorates and Masters

Multiple-choice questions are one of the questions commonly used in assessments. It is widely used because this type of examination can be an effective and reliable way to examine the level of student’s knowledge. So far, this type of examination can either be marked by hand or with specialised answer sheets and scanning equipment. There are specialised answer sheets and scanning equipment to mark multiple-choice questions automatically. However, these are expensive, specialised and restrictive answer sheets and optical mark recognition scanners.

This research aims to design and implement a multiple-choice answer sheet and a reliable image processing-based scoring system that …

Evolving Gameplay Elements Into Virtual Terrains, Andrew Pech

Theses: Doctorates and Masters

With advancements in technology, consumers are expecting higher quality and more detailed video game content. This puts a strain on video game companies and their developers as they are required to manually design and create increasingly complex video game content. Procedural content generation can alleviate this burden by using technology to automatically generate video game content, effectively reducing development time and budget. This thesis presents a novel approach towards procedurally generating video game terrains that meet a set of gameplay requirements as specified by the user. This approach uses a genetic algorithm to evolve a set of modifications that, when …

Next Generation Wireless Communication Networks: Energy And Quality Of Service Considerations, Md Munjure Mowla

Theses: Doctorates and Masters

The rapid growth in global mobile phone users has resulted in an ever-increasing demand for bandwidth and enhanced quality-of-service (QoS). Several consortia comprising major international mobile operators, infrastructure manufacturers, and academic institutions are working to develop the next generation wireless communication systems fifth generation (5G) - to support high data rates and increased QoS. 5G systems are also expected to represent a greener alternative for communication systems, which is important because power consumption from the information and communication technology (ICT) sector is forecast to increase significantly by 2030. The deployment of ultra-dense heterogeneous small cell networks (SCNs) is expected to …

On The Spatial Modelling Of Mixed And Constrained Geospatial Data, Hassan Talebi

Theses: Doctorates and Masters

Spatial uncertainty modelling and prediction of a set of regionalized dependent variables from various sample spaces (e.g. continuous and categorical) is a common challenge for geoscience modellers and many geoscience applications such as evaluation of mineral resources, characterization of oil reservoirs or hydrology of groundwater. To consider the complex statistical and spatial relationships, categorical data such as rock types, soil types, alteration units, and continental crustal blocks should be modelled jointly with other continuous attributes (e.g. porosity, permeability, seismic velocity, mineral and geochemical compositions or pollutant concentration). These multivariate geospatial data normally have complex statistical and spatial relationships which should …

Development Of Novel Phenanthroline And Thiazole Orange Derived G-Quadruplex Ligands And Telomerase Inhibitors, Siwen Wang

University of the Pacific Theses and Dissertations

The end of the human chromosome is protected by telomeres which contain a special tandem guanine-rich DNA sequence, 5’-TTAGGG. The length of telomeres is shortened during cell replications, and its length limits the replication capacity of cells. Telomerase is over-expressed in 85–90% of cancer cells, responsible for extending the telomere length in cancer cells. Guanine-rich DNA sequence can self-assemble into unique G-quadruplex structures that interfere with the extension of telomeres by telomerase. Therefore, DNA G-quadruplex has recently received much attention because of its important regulatory functions in telomerase-mediated cancerization. The formation of G-quadruplex requires monovalent cations (Na+ and K+) or …

Dna Lesions Produced From The Reaction Of Diols And 5-Formylcytosine And Their Effects On Dna Replication, Brock Allen

University of the Pacific Theses and Dissertations

Nucleic acids are complex macromolecules that are susceptible to both endogenous and exogenous damage. This study explored damage resulting from interactions with environmental nucleophilic toxins, such as a variety of diols and amines found in industry. These nucleophiles can react with electrophilic groups, such as 5-formylcytosine. 5-formylcytosine is an oxidation product of the epigenetic base 5-methylcytosine. It is typically removed by thymine DNA glycosylase (TDG) but is known to accumulate in the genome, making the formyl group susceptible to attack. In this study we used GC/MS and ESI-MS to show that DNA lesions from the nucleophilic addition reaction of toxins …

Bimetallic Complexes: The Fundamental Aspects Of Metal-Metal Interactions, Ligand Sterics And Application, Michael Bernard Pastor

University of the Pacific Theses and Dissertations

Metal containing complexes have been used to catalyze various organic transformations for the past few decades. The success of several mononuclear catalysts led to transition metal catalysts used in pharmaceuticals, environmental, and industrial processes. While mononuclear complexes have been used extensively, bimetallic systems have received far less attention. Bimetallic or polynuclear sites are commonly found in metalloenzymes that perform elegant transformation in biological systems, underlying their significance. Inorganic chemists take inspiration from nature and design model bimetallic complexes to further study this cooperativity effect. A bimetallic platform offers many structural and functional differences such as the identity of the metal …