Physical Sciences and Mathematics Commons^™

Potential For Biocontrol Of Environmental Vibrio Spp. By Predatory Bacteria Bacteriovorax, Patrick Tennis

OES Theses and Dissertations

The scale of predator-prey interactions varies from the iconic (e.g., lions and gazelles) to the microscopic (e.g., protists and bacteria). Bdellovibrio-and-like-organisms (BALOs) are bacteria that prey upon other Gram-negative bacteria, including pathogens. In particular, the halophilic genus Vibrio, many species of which are disease agents, has been shown to be susceptible to attack by BALOs. One motivation of the present research is to assess the potential for biocontrol of Vibrio by Bacteriovorax. This investigation is the first to test the susceptibility of Vibrio strains (n = 26) originating from a variety of geographic locations to predation by …

Avoiding Spoilers On Mediawiki Fan Sites Using Memento, Shawn M. Jones

Computer Science Theses & Dissertations

A variety of fan-based wikis about episodic fiction (e.g., television shows, novels, movies) exist on the World Wide Web. These wikis provide a wealth of information about complex stories, but if readers are behind in their viewing they run the risk of encountering spoilers" -- information that gives away key plot points before the intended time of the show's writers. Enterprising readers might browse the wiki in a web archive so as to view the page prior to a specific episode date and thereby avoid spoilers. Unfortunately, due to how web archives choose the "best" page, it is still possible …

Development Of Superconducting Spoke Cavities For High-Velocity Applications, Christopher Shawn Hopper

Physics Theses & Dissertations

To date, superconducting spoke cavities have been designed, developed, and tested for particle velocities up to β0 ~ 0.6, but there is a growing interest in possible applications of spoke cavities for high-velocity applications. The first task is to explore the design parameter space for low-frequency, high-velocity, single- and double-spoke superconducting cavities in order to determine how each design parameter affects the electromagnetic properties, in particular the surface electromagnetic fields and the shunt impedance. Once an electromagnetically optimized, high-velocity spoke cavity is designed, there are several other characteristics that need to be investigated. These include multipacting scenarios, higher-order mode excitation …

Photoassociative Spectroscopy Of Ultracold Argon And Krypton Confined In A Magneto Optical Trap, Maha Khaled Omar

Physics Theses & Dissertations

Creating ultracold molecules has attracted considerable interest in the last decade. Once created, such molecules can be used for precision spectroscopy or to study chemical reactions at ultracold tem peratures. Several techniques have been developed to produce ultracold molecules; the most common is photoassociation where two ultracold atoms collide in the presence of light that induces a free-bound transition to an excited molecular state. Photoassociation can also be used to perform spectroscopy in order to map out the ro-vibrational levels of a molecular state. In this dissertaiotn, we report on our Photoasociative Spectroscopy (PAS) studies conducted separately in argon and …

Toward A Theory Of Multi-Method Modeling And Simulation Approach, Mariusz A. Balaban

Computational Modeling & Simulation Engineering Theses & Dissertations

The representation via simulation models can easily lead to simulation models too simple for their intended purpose, or with too much detail, making them hard to understand. This problem is related to limitations of the modeling and simulation methods. A multi-method Modeling and Simulation (M&S) approach has the potential for improved representation by taking advantage of methods' strengths and mitigating their weaknesses. Despite a high appeal for using multiple M&S methods, several related problems should be addressed first. The current level of theoretical, methodological, and pragmatic knowledge related to a multi-method M&S approach is limited. It is problematic that there …

Meson Photo-Couplings From Lattice Quantum Chromodynamics, Christian J. P. Shultz

Physics Theses & Dissertations

We explore the calculation of three-point functions featuring a vector current insertion in lattice Quantum Chromodynamics. These three-point functions, in general, contain information about many radiative transition matrix elements simultaneously. We develop and implement the technology necessary to isolate a single matrix element via the use of optimized operators, operators designed to interpolate a single meson eigenstate, which are constructed as variationally optimized linear combination of meson interpolating fields within a large basis. In order to frame the results we also explore some well known phenomenology arising within the context of the constituent quark model before transitioning to a lattice …

Zero-Inflated Models To Identify Transcription Factor Binding Sites In Chip-Seq Experiments, Sameera Dhananjaya Viswakula

Mathematics & Statistics Theses & Dissertations

It is essential to determine the protein-DNA binding sites to understand many biological processes. A transcription factor is a particular type of protein that binds to DNA and controls gene regulation in living organisms. Chromatin immunoprecipitation followed by highthroughput sequencing (ChIP-seq) is considered the gold standard in locating these binding sites and programs use to identify DNA-transcription factor binding sites are known as peak-callers. ChIP-seq data are known to exhibit considerable background noise and other biases. In this study, we propose a negative binomial model (NB), a zero-inflated Poisson model (ZIP) and a zero-inflated negative binomial model (ZINB) for peak-calling. …

Modeling And Simulation Of Molecular Couette Flows And Related Flows, Wei Li

Mathematics & Statistics Theses & Dissertations

In this thesis, molecular Couette flow is clearly defined and the modeling and simulation of this kind of flow is systematically investigated. First, the integral equations for the velocity of gaseous Couette flow and related flows are derived from linearized Boltzmann BGK equation with Maxwell boundary condition and solved with high precision by using Chebyshev collocation and chunk-based collocation methods. The velocity profiles of gaseous Couette flows and related flows with a wide range of Knudsen number and the Maxwell boundary condition of various accommodation ratios are obtained. Moreover, the order of convergence of the numerical methods is also discussed …

Wireless Networking For Vehicle To Infrastructure Communication And Automatic Incident Detection, Sarwar Aziz Sha-Mohammad

Computer Science Theses & Dissertations

Vehicular wireless communication has recently generated wide interest in the area of wireless network research. Automatic Incident Detection (AID), which is the recent focus of research direction in Intelligent Transportation System (ITS), aims to increase road safety. These advances in technology enable traffic systems to use data collected from vehicles on the road to detect incidents. We develop an automatic incident detection method that has a significant active road safety application for alerting drivers about incidents and congestion. Our method for detecting traffic incidents in a highway scenario is based on the use of distance and time for changing lanes …

Multi-Surface Simplex Spine Segmentation For Spine Surgery Simulation And Planning, Rabia Haq

Computational Modeling & Simulation Engineering Theses & Dissertations

This research proposes to develop a knowledge-based multi-surface simplex deformable model for segmentation of healthy as well as pathological lumbar spine data. It aims to provide a more accurate and robust segmentation scheme for identification of intervertebral disc pathologies to assist with spine surgery planning. A robust technique that combines multi-surface and shape statistics-aware variants of the deformable simplex model is presented. Statistical shape variation within the dataset has been captured by application of principal component analysis and incorporated during the segmentation process to refine results. In the case where shape statistics hinder detection of the pathological region, user-assistance is …

A Framework And System For A Multi-Model Decision Aid For Sustainable Farming Practices, Kasi Bharath Vegesana

Computational Modeling & Simulation Engineering Theses & Dissertations

Decision support systems (DSS) for farmers address the need for modeling multiple processes and scenarios that affect farmer decision making. Existing DSS have various drawbacks that stop them from being deployed as decision support tools. This research proposes a multi-model simulation framework that can be used to analyze farm management practices at the crop level, individual farm level and at the community level to show the impact and alternatives for smallholder farming practices. A generic crop growth model is proposed, based on existing equations. We run sensitivity analysis on the model to identify important variables. The outputs from the crop …

De Novo Protein Structure Modeling And Energy Function Design, Lin Chen

Computer Science Theses & Dissertations

The two major challenges in protein structure prediction problems are (1) the lack of an accurate energy function and (2) the lack of an efficient search algorithm. A protein energy function accurately describing the interaction between residues is able to supervise the optimization of a protein conformation, as well as select native or native-like structures from numerous possible conformations. An efficient search algorithm must be able to reduce a conformational space to a reasonable size without missing the native conformation. My PhD research studies focused on these two directions.

A protein energy function—the distance and orientation dependent energy function of …