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Articles 3331 - 3360 of 143289

Full-Text Articles in Physical Sciences and Mathematics

A Gravity Model Integrating Land-Use And Transportation Policies For Sustainable Development: Case Study Of Fresno, California, Chih-Hao Wang, Na Chen Apr 2023

A Gravity Model Integrating Land-Use And Transportation Policies For Sustainable Development: Case Study Of Fresno, California, Chih-Hao Wang, Na Chen

Mineta Transportation Institute

The idea of urban compaction has been long proposed and promoted to address the problem of urban sprawl in many American cities. However, there are still rare successful cases of such implementation in the United States. This study uses a classic gravity model, TELEM (Transpiration, Economic, and Land-Use Model) to examine to what extent a land-use or transportation policy must be regulated to make the urban compaction occur in a typical auto-dependent city—Fresno, California. Five scenarios are considered (BL, L1, L2, T1, and T2), in which the baseline (BL) is a natural growth scenario. Without any policy interventions, the city …

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What You Don't See: The Impact Of Hidden Game Mechanics On Players, Jan Virsunen Apr 2023

What You Don't See: The Impact Of Hidden Game Mechanics On Players, Jan Virsunen

ART 108: Introduction to Games Studies

Since the rise of technology in the early nineteen sixties the art of gaming became an increasingly popular form of entertainment for many people throughout the years. As time progressed so did the advancements in technology which allowed for video games to become more immersive, captivating, and complex. Due to these advancements in tech, it generated a wide variety of ways for developers to increase game complexities. However, as the complexity of video games has increased, so too has the number of hidden game mechanics. These game mechanics are seen as the underlying systems and rules that govern how the …

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Dairy & Development: An Investigation Into The Economic And Sociopolitical Dynamics Of Yak Cheesemaking In Nepal, Audrey Peiker Apr 2023

Dairy & Development: An Investigation Into The Economic And Sociopolitical Dynamics Of Yak Cheesemaking In Nepal, Audrey Peiker

Independent Study Project (ISP) Collection

Cheesemaking in Nepal is full of love, passion, and creativity. What began as a Swiss development project in the 1950s has now grown into a full-fledged industry, providing jobs, creative outlets, and cultural expression for many. Nepal’s Dairy Development Corporation owns several factories throughout the country, setting the tone for the industry by establishing the standard price for milk and process for cheesemaking. From there, privately held factories innovate and compete, bringing new products to the market and increasing wages, but also struggle with consistency and reliability. Now, Nepal’s cheesemaking market is at a turning point—much of the herding population …

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Talking To The Earth: A Digital Documentation Of Biodiversity In The Sherpa Language, Dvij Sharma Apr 2023

Talking To The Earth: A Digital Documentation Of Biodiversity In The Sherpa Language, Dvij Sharma

Independent Study Project (ISP) Collection

Identified as a pressing matter by organizations as prominent as the UN, the conservation of minority and indigenous languages “is essential for ensuring the continuation and transmission of culture, customs, and history, but it is also important to address biodiversity loss and climate change.” This project focuses on one of the latter issues, biodiversity loss, as it relates to Sherpa, a minority language spoken primarily in Eastern Nepal. In an effort to help preserve the native vocabulary and descriptions of basic plants and animals found in Sherpa-speaking regions, primarily interview-based fieldwork was conducted in the lower Solu regions of Lumsa, …

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Ecological Living In Nepali Food Systems: A Synthesis Of Circular Nutrient And Knowledge Flows In The Kathmandu Valley, Kaitlyn Feely Apr 2023

Ecological Living In Nepali Food Systems: A Synthesis Of Circular Nutrient And Knowledge Flows In The Kathmandu Valley, Kaitlyn Feely

Independent Study Project (ISP) Collection

Researching food-systems in Nepal can feel like drinking from a fire hydrant. Sixty-six percent of the population is directly involved in agriculture and a diverse set of ecocultural understandings influence the practice across the country’s landscapes, ranging from the Himalayas to urban centers to southern plains. In the Kathmandu Valley and peripheral hills where I conducted my research, seemingly any spare land was under cultivation, enabled by fertile ground, optimal climate, and market potential. But despite the prevalence of farming in daily life throughout the country, Nepal’s food system is not domestically self-sufficient. A complex web of imports and exports …

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Status Of Pangolins: A Case Study On "The Most Trafficked Mammal In The World" In Central-South Of Nepal, Tsogyal Wangmo Lama Apr 2023

Status Of Pangolins: A Case Study On "The Most Trafficked Mammal In The World" In Central-South Of Nepal, Tsogyal Wangmo Lama

Independent Study Project (ISP) Collection

Pangolins are subject to constant trafficking in Asia and increasingly in Africa for their meat and scales. Very little research is done on this species due to its nocturnal, burrowing, and elusive nature. The larger the size of an animal is, the better it is known to the people and vice versa. Hence all these eight species of pangolins despite being under the International Union for Conservation of Nature (IUCN) red list with the four Asian species declared endangered or critically endangered, are still illegally abused and used for ulterior motives due to a lack of awareness among the general …

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Biodiversidad De Plantas En La Reserva Natural Urbana Punta Popper En Río Grande: Una Propuesta Para Senderos Para La Gestión De La Conservación Y Métodos De Campo Replicables En Un Etorno Educativo, Lili Weir Apr 2023

Biodiversidad De Plantas En La Reserva Natural Urbana Punta Popper En Río Grande: Una Propuesta Para Senderos Para La Gestión De La Conservación Y Métodos De Campo Replicables En Un Etorno Educativo, Lili Weir

Independent Study Project (ISP) Collection

The Patagonian Steppe is an ecoregion that is rich in plant biodiversity (both native and introduced), and the Urban Nature Reserves like Punta Popper in Río Grande provide an opportunity to preserve these sensitive species and educate the public, especially students, about the value of this trophic level. However, many beautiful species are being affected by human activities in the Reserve: such as the mismanagement of the trail systems which has led to erosion of the sand dunes, and the pressures of rapid urban expansion contributing to trash pollution. It is essential that stakeholder communities have access to information and …

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Considerations For Solar Development: Comprehensive Assessment Of Solar Production Benefits And Consequences In Portugal, Jonathan Ramos Marcuse Apr 2023

Considerations For Solar Development: Comprehensive Assessment Of Solar Production Benefits And Consequences In Portugal, Jonathan Ramos Marcuse

Independent Study Project (ISP) Collection

In this paper, the potential for solar energy development in Portugal is explored, with a focus on the Alentejo region of Portugal. The Fernando Pessoa Photovoltaic plant that is approved for construction in the Santiago do Cacém municipality is analyzed. The size of the plant and the location are considered when studying the environmental, social, and economic impacts of the project. The possibility of a centralized solar array in Sines is also explored as an alternative, taking into account the environmental and social impacts on local communities. Additionally, the feasibility and benefits of implementing a decentralized energy grid, utilizing scattered …

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Agroforestry For The Future: Motivations Behind Tasmanian Farmers Planting Trees, Josh Lipp Apr 2023

Agroforestry For The Future: Motivations Behind Tasmanian Farmers Planting Trees, Josh Lipp

Independent Study Project (ISP) Collection

Agroforestry is the act of combining farming and tree planting, and many Tasmanian farmers are starting to plant trees on their properties for multiple reasons. Through conducting 9 interviews with farmers and researchers and visiting field sites, 3 main themes were identified to answer the question: why are Tasmanian farmers planting trees, and what are the benefits and downsides to agroforestry? Interviews help us understand farmers’ perceptions of agroforestry, and field data collection will prove the benefits of agroforestry in the future. Tasmania was chosen as the location of study as it is a state in Australia that largely focuses …

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Critical Workforce Skills For Bachelor-Level Geoscientists: An Analysis Of Geoscience Job Advertisements, G. W. Shafer, K. Viskupic, A. E. Egger Apr 2023

Critical Workforce Skills For Bachelor-Level Geoscientists: An Analysis Of Geoscience Job Advertisements, G. W. Shafer, K. Viskupic, A. E. Egger

Geosciences Faculty Publications and Presentations

Understanding the skills bachelor-level geoscientists need to enter the workforce is critical to their success. The goal of this study was to identify the workforce skills that are most requested from a broad range of geoscience employers. We collected 3668 job advertisements for bachelor-level geoscientists and used a case-insensitive, code-matching function in Matlab to determine the skills geoscience employers seek. Written communication (67%), field skills (63%), planning (53%), and driving (51%) were most frequently requested. Field skills and data collection were frequently found together in the ads. Written communication skills were common regardless of occupation. Quantitative skills were requested less …

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Tectonomagmatic Evolution Of Southwestern Laurentia: Insights From Zircon U-Pb Geochronology And Hafnium Isotopic Composition Of The Red Bluff Granite Suite, West Texas, Usa, Munazzam Ali Mahar, Philip C. Goodell, Jason W. Ricketts, Eric J. Kappus, James L. Crowley, Anthony M. Alvarez Apr 2023

Tectonomagmatic Evolution Of Southwestern Laurentia: Insights From Zircon U-Pb Geochronology And Hafnium Isotopic Composition Of The Red Bluff Granite Suite, West Texas, Usa, Munazzam Ali Mahar, Philip C. Goodell, Jason W. Ricketts, Eric J. Kappus, James L. Crowley, Anthony M. Alvarez

Geosciences Faculty Publications and Presentations

We provide laser ablation–multicollector–inductively coupled plasma–mass spectrometry (LA-MC-ICP-MS) and high-precision chemical abrasion–isotope dilution–thermal ionization mass spectrometry (CA-ID-TIMS) U-Pb ages and Hf isotopic compositions of zircons from the Red Bluff Granite Suite and mafic dikes in the Franklin Mountains of El Paso, Texas, USA. Granitoids exposed in the Franklin Mountains were previously divided into five magmatic stages based on cross-cutting relationships. Major and trace element compositions showed that these granitoids are ferroan, alkaline, and A2 type. Homogeneity in the whole-rock geochemistry suggests that the granite stages are genetically related and share similar petrogenetic histories. Weighted mean zircon 206Pb/238U …

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Coastal Morphology And Sediment Deposition On Adjacent Coral Reefs At Misali Island, Sophia Rosati Apr 2023

Coastal Morphology And Sediment Deposition On Adjacent Coral Reefs At Misali Island, Sophia Rosati

Independent Study Project (ISP) Collection

Terrestrial and marine ecosystems are frequently interpreted under separate lenses. On a 1 km wide island, however, these two sciences are inextricably tied. Misali Island, a small coralline island in the Indian Ocean, has been largely uninhabited for its entire history, making this coastal interface unique. In this study, Misali Island is used as a study region to demonstrate how natural processes are materializing in the Zanzibar Archipelago. Methods employed, both geological and marine, work to understand the erosional circumstances of Baobab Beach and the inherent effects on local coral reefs. Results show that Misali’s northeastern beachfront is currently under …

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Evaluating The On-Site Impacts Of The Ambatovy Project Through The Lens Of Environmental Justice, Nick Karlik Apr 2023

Evaluating The On-Site Impacts Of The Ambatovy Project Through The Lens Of Environmental Justice, Nick Karlik

Independent Study Project (ISP) Collection

In Madagascar, sustainable development has been established and maintained by dominant foreign actors to reconcile neoliberalism with globalized conceptions of environmental protection. The Ambatovy mining and refining project has emerged as a prominent example of this developmental mode; Ambatovy is the largest economic enterprise in the history of the country and one of the largest and most productive mining operations in the world, generating billions of dollars in revenue for a country that remains among the poorest in the world while offsetting its impact on endemic biodiversity and forest habitat through conservation initiatives. At the same time, the evaluative framework …

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Community Participation And Perspectives Of Ambondrolava Mangrove Restoration Project, Nadine Shannon Apr 2023

Community Participation And Perspectives Of Ambondrolava Mangrove Restoration Project, Nadine Shannon

Independent Study Project (ISP) Collection

Madagascar’s mangrove forests are intertidal ecosystems that provide numerous valuable ecosystem services but are nonetheless under pressure from large amounts of deforestation. On the southwestern coast of Madagascar, the village of Ambondrolava practices community led management of the mangrove and its resources. This research project studied the evolution of the mangrove area using GIS data, and investigated, through interviews, the relationship between the local community of Ambondrolava and the organizations that manage the mangrove ecosystem. From 2000 to 2018, the zone of the mangrove has experienced a net loss in area every year, despite reforestation efforts. Most community members interviewed …

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Consumo Verde ¿Para Quién?: Las Tierras, Cosmovisiones, Y Personas Escondidas Detrás De La Fiebre Del Oro Blanco / Green Consumption, For Who?: The Lands, World Views, And People Hidden Behind The White Gold Rush., Gabriel Gómez Apr 2023

Consumo Verde ¿Para Quién?: Las Tierras, Cosmovisiones, Y Personas Escondidas Detrás De La Fiebre Del Oro Blanco / Green Consumption, For Who?: The Lands, World Views, And People Hidden Behind The White Gold Rush., Gabriel Gómez

Independent Study Project (ISP) Collection

La “Transición energética” a consumo verde ha sido reconocida globalmente como el camino necesario para evitar lo peor de la crisis climática, pero es una solución que depende en un aumento del litio. La manera más usada para extraer el litio genera impactos destructivos en los ambientes que contienen el recurso, y en Sudamérica, donde los habitantes son mayormente indígena. Usando las comunidades de Salinas Grandes y Laguna de Guayatayoc en Jujuy, Argentina como un caso práctico, este proyecto propone analizar cómo el discurso hegemónico del consumo verde invisibiliza a gente indígena, y cómo estas comunidades resisten entendimientos occidentales y …

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A Transition Point: The Role Of The Global Power Shift In Facilitating Saudi Internal Reforms, Aidan Aguilar Apr 2023

A Transition Point: The Role Of The Global Power Shift In Facilitating Saudi Internal Reforms, Aidan Aguilar

Independent Study Project (ISP) Collection

The increasing political and economic influence of China represents a pivotal point within international relations. This paper aims to explore the implications of this global power shift on Saudi Arabia’s attempted economic reforms. The Kingdom’s reliance on oil has created an unsustainable economic model, and this model is intrinsically linked to Saudi Arabia’s relationship with the United States. Its growing relationship with China could create change. As such, this paper analyzes the intersection of economics and security in relation to the Saudi Vision 2030. I argue that, not only does China serve as an important source of the investment necessary …

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Mth 50 Syllabus, Koby Kohulan Mar 2023

Mth 50 Syllabus, Koby Kohulan

Open Educational Resources

No abstract provided.

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Exploration Of C9or72c9-500 Sk2, Sk3 Channel Expression, Teresa L. Garrett Mar 2023

Exploration Of C9or72c9-500 Sk2, Sk3 Channel Expression, Teresa L. Garrett

Festival of Research

ALS (also known as Lou Gehrig's Disease) is a neurodegenerative disease that weakens muscles and impacts physical function. The C9 Gene is responsible for creating proteins that help neurons send and receive signals across the synapse. Small Conductance calcium activated potassium channels (SK channels) affect the hyperpolarization phase of an action potential. Hypothesis: SK2 and SK3 clusters of C9 positive cells should decrease in size and intensity when exposed to a disease state compared to C9 negative controls.

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Dynamic Equations, Control Problems On Time Scales, And Chaotic Systems, Martin Bohner Mar 2023

Dynamic Equations, Control Problems On Time Scales, And Chaotic Systems, Martin Bohner

Mathematics and Statistics Faculty Research & Creative Works

The unification of integral and differential calculus with the calculus of finite differences has been rendered possible by providing a formal structure to study hybrid discrete-continuous dynamical systems besides offering applications in diverse fields that require simultaneous modeling of discrete and continuous data concerning dynamic equations on time scales. Therefore, the theory of time scales provides a unification between the calculus of the theory of difference equations with the theory of differential equations. In addition, it has become possible to examine diverse application problems more precisely by the use of dynamical systems on time scales whose calculus is made up …

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Final Revised Residential Metals Abatement Program (Rmap) (Non-Residential Parcels) 2021 Data Summary Report (Dsr), Environmental Standards, Inc., Pioneer Technical Services, Inc. Mar 2023

Final Revised Residential Metals Abatement Program (Rmap) (Non-Residential Parcels) 2021 Data Summary Report (Dsr), Environmental Standards, Inc., Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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2023 Final Butte Reduction Works (Brw) Smelter Area Mine Waste Remediation And Contaminated Groundwater Hydraulic Control Site Organic Pollutant Surface Water Sampling Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. Mar 2023

2023 Final Butte Reduction Works (Brw) Smelter Area Mine Waste Remediation And Contaminated Groundwater Hydraulic Control Site Organic Pollutant Surface Water Sampling Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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Snowmass 2021 Computational Frontier Compf4 Topical Group Report Storage And Processing Resource Access, W. Bhimji, D. Carder, E. Dart, J. Duarte, I. Fisk, R. Gardner, C. Guok, B. Jayatilaka, T. Lehman, M. Lin, C. Maltzahn, S. Mckee, M. S. Neubauer, O. Rind, O. Shadura, N. V. Tran, P. Van Gemmeren, G. Watts, B. A. Weaver, F. Würthwein Mar 2023

Snowmass 2021 Computational Frontier Compf4 Topical Group Report Storage And Processing Resource Access, W. Bhimji, D. Carder, E. Dart, J. Duarte, I. Fisk, R. Gardner, C. Guok, B. Jayatilaka, T. Lehman, M. Lin, C. Maltzahn, S. Mckee, M. S. Neubauer, O. Rind, O. Shadura, N. V. Tran, P. Van Gemmeren, G. Watts, B. A. Weaver, F. Würthwein

Holland Computing Center: Faculty Publications

The Snowmass 2021 CompF4 topical group’s scope is facilities R&D, where we consider “facilities” as the hardware and software infrastructure inside the data centers plus the networking between data centers, irrespective of who owns them, and what policies are applied for using them. In other words, it includes commercial clouds, federally funded High Performance Computing (HPC) systems for all of science, and systems funded explicitly for a given experimental or theoretical program. However, we explicitly consider any data centers that are integrated into data acquisition systems or trigger of the experiments out of scope here. Those systems tend to have …

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Perceptions Of Political Violence, Trisha Patel, Andrew Wachtel, Cameron N. Smith Mar 2023

Perceptions Of Political Violence, Trisha Patel, Andrew Wachtel, Cameron N. Smith

Belmont University Research Symposium (BURS)

Recently, political violence in the United States has been an increasingly salient public issue. Previous statistical connections have been made between low yearly income, low education, and right-wing political affiliation to a higher acceptance of political violence (Jasko et al., 2022). Using a dataset published through Harvard, this study aims to address the white population and their beliefs regarding current issues. The dataset was previously assembled by researchers studying the connection of people’s faith to political tendencies. Data is currently being analyzed and results will be presented at BURS.

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Air Pollution In South Texas: A Short Communication Of Health Risks And Implications, Sai Deepak Pinakana, Esmeralda Mendez, Ismaila Ibrahim, Md. Salahuddin Majumder, Amit U. Raysoni Mar 2023

Air Pollution In South Texas: A Short Communication Of Health Risks And Implications, Sai Deepak Pinakana, Esmeralda Mendez, Ismaila Ibrahim, Md. Salahuddin Majumder, Amit U. Raysoni

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Air pollution is a major public health concern. The region of South Texas in the United States has experienced high levels of air pollution in recent years due to an increase in population, cross-border trade between the U.S.A. and Mexico, and high vehicular activity. This review assesses the relationships between human health and air pollution in South Texas. A thorough scientific search was performed using PubMed, Science Direct, and ProQuest, with most of the literature focusing on the source apportionment of particulate matter that is 2.5 microns or less in width (PM2.5), Carbon Dioxide (CO2), carbon monoxide (CO), Black Carbon …

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Continuous Semi-Supervised Nonnegative Matrix Factorization, Michael R. Lindstrom, Xiaofu Ding, Feng Liu, Anand Somayajula, Deanna Needell Mar 2023

Continuous Semi-Supervised Nonnegative Matrix Factorization, Michael R. Lindstrom, Xiaofu Ding, Feng Liu, Anand Somayajula, Deanna Needell

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Nonnegative matrix factorization can be used to automatically detect topics within a corpus in an unsupervised fashion. The technique amounts to an approximation of a nonnegative matrix as the product of two nonnegative matrices of lower rank. In certain applications it is desirable to extract topics and use them to predict quantitative outcomes. In this paper, we show Nonnegative Matrix Factorization can be combined with regression on a continuous response variable by minimizing a penalty function that adds a weighted regression error to a matrix factorization error. We show theoretically that as the weighting increases, the regression error in training …

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Interface-Engineered Ferroelectricity Of Epitaxial Hf0.5Zr0.5O2 Thin Films, Shu Shi, Haolong Xi, Tengfei Cao, Weinan Lin, Zhongran Liu, Jiangzhen Niu, Da Lan, Chenghang Zhou, Jing Cao, Hanxin Su, Tieyang Zhao, Ping Yang, Yao Zhu, Xiaobing Yan, Evgeny Y. Tsymbal, He Tian, Jingsheng Chen Mar 2023

Interface-Engineered Ferroelectricity Of Epitaxial Hf0.5Zr0.5O2 Thin Films, Shu Shi, Haolong Xi, Tengfei Cao, Weinan Lin, Zhongran Liu, Jiangzhen Niu, Da Lan, Chenghang Zhou, Jing Cao, Hanxin Su, Tieyang Zhao, Ping Yang, Yao Zhu, Xiaobing Yan, Evgeny Y. Tsymbal, He Tian, Jingsheng Chen

Department of Physics and Astronomy: Faculty Publications

Ferroelectric hafnia-based thin films have attracted intense attention due to their compatibility with complementary metal-oxide-semiconductor technology. However, the ferroelectric orthorhombic phase is thermodynamically metastable. Various efforts have been made to stabilize the ferroelectric orthorhombic phase of hafnia-based films such as controlling the growth kinetics and mechanical confinement. Here, we demonstrate a key interface engineering strategy to stabilize and enhance the ferroelectric orthorhombic phase of the Hf0.5Zr0.5O2 thin film by deliberately controlling the termination of the bottom La0.67Sr0.33MnO3 layer. We find that the Hf0.5Zr0.5O2 films on …

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Draft Final Quarterly Operations And Maintenance Report Butte Treatment Lagoon System – Fourth Quarter 2022, Pioneer Technical Services, Inc. Mar 2023

Draft Final Quarterly Operations And Maintenance Report Butte Treatment Lagoon System – Fourth Quarter 2022, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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Traffic Lights For Catalysis: Stimuli-Responsive Molecular And Extended Catalytic Systems, Grace C. Thaggard, Johanna Haimeri, Roland A. Fischer Prof. Dr., Kyoung Chul Park, Natalia B. Shustova Prof. Dr. Mar 2023

Traffic Lights For Catalysis: Stimuli-Responsive Molecular And Extended Catalytic Systems, Grace C. Thaggard, Johanna Haimeri, Roland A. Fischer Prof. Dr., Kyoung Chul Park, Natalia B. Shustova Prof. Dr.

Faculty Publications

The advances made in the field of stimuli-responsive catalysis during the last five years with a focus on the novel recently-emerged directions and applications have been surveyed. Metal-free catalysts and organometallic complexes, as well as biomimetic systems and extended structures, which display switchable catalytic activity for a variety of organic transformations, are discussed. Light-activated systems comprised of photochromic molecules capable of modulating reaction rate, yield, or enantioselectivity based on geometric and electronic changes associated with photoisomerization are the focus of the detailed discussion. Alternative stimuli, including pH and temperature, which could be applied either alone or in combination with light, …

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Ten Years After Imagenet: A 360° Perspective On Artificial Intelligence, Sanjay Chawla, Preslav Nakov, Ahmed Ali, Wendy Hall, Issa Khalil, Xiaosong Ma, Husrev Taha Sencar, Ingmar Weber, Michael Wooldridge, Ting Yu Mar 2023

Ten Years After Imagenet: A 360° Perspective On Artificial Intelligence, Sanjay Chawla, Preslav Nakov, Ahmed Ali, Wendy Hall, Issa Khalil, Xiaosong Ma, Husrev Taha Sencar, Ingmar Weber, Michael Wooldridge, Ting Yu

Natural Language Processing Faculty Publications

It is 10 years since neural networks made their spectacular comeback. Prompted by this anniversary, we take a holistic perspective on artificial intelligence (AI). Supervised learning for cognitive tasks is effectively solved - provided we have enough high-quality labelled data. However, deep neural network models are not easily interpretable, and thus the debate between blackbox and whitebox modelling has come to the fore. The rise of attention networks, self-supervised learning, generative modelling and graph neural networks has widened the application space of AI. Deep learning has also propelled the return of reinforcement learning as a core building block of autonomous …

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Stabilizing G-Quadruplex Dna And Rna Structures With Ionic Liquids, Timothy Vaden Mar 2023

Stabilizing G-Quadruplex Dna And Rna Structures With Ionic Liquids, Timothy Vaden

Faculty Scholarship for the College of Science & Mathematics

Stabilizing DNA and RNA for long-term room-temperature storage is important for many biotechnological applications including oncology pharmaceuticals and mRNA-based vaccines (e.g. Covid vaccines). This poster shows that ionic liquids can improve the thermal stability of G-quadruplex DNA and RNA structures, and motivates further studies of ionic liquid-based materials for DNA / RNA stabilization.

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