Physical Sciences and Mathematics Commons^™

Sex-Based Disparities In Artificial Intelligence For Cardiovascular Disease: A Scoping Review, Maurgan Lee, Tarek Atasi, Michael Mclellan, Yodit Beru, Jason Booza

Population, Patient, Physician and Professionalism Projects

No abstract provided.

Study Of A Nonlinear Delayed Parabolic Model For Prion Disease Dynamics With The Unfolded Protein Response, Gangadhara Boregowda, Laurent Pujo-Menjouet, Zhaosheng Feng, Michael R. Lindstrom

School of Mathematical & Statistical Sciences Faculty Publications

Prion diseases are neurodegenerative disorders characterized by the dynamic spread of misfolded toxic proteins in the brain. In this process, the normal cellular prion protein (PrPC) produced by neurons misfolds into a toxic form known as scrapie prion protein (PrPSc). These misfolded proteins propagate through the brain by converting healthy prions into their toxic form. This biological mechanism can be modeled by a system of nonlinear parabolic partial differential equations, accompanied by a nonlinear delayed integral boundary condition. Our primary objective is to establish the existence of nonnegative classical solutions to this system. Furthermore, we derive a priori estimates for …

2026 October 1 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

State-Aware Fuzzing Of Javascript Engines With Llm-Guided Instrumentation, Wai Kin Wong, Dongwei Xiao, Cheuk Tung Lai, Ping Fan Ke, Shuai Wang

Research Collection School Of Computing and Information Systems

The security of the modern web depends on the correctness of JavaScript (JS) engines, yet these complex systems remain vulnerable to high-impact bugs. A critical limitation of state-of-the-art fuzzers is the coverage plateau: once a fuzzer saturates the control-flow graph, edge coverage loses its ability to guide discovery. Because complex engine behaviors, such as JIT optimization tiers and hidden class transitions, often share identical edge coverage, standard coverage metrics are blind to the distinct internal states required to trigger deep errors. To bridge this gap, we present StateLens, a framework that employs Large Language Models (LLM) to automate the discovery …

Size-Tunable Tellurium Quantum Dots By Glancing Angle Deposition, S. M. Sayem, Salim Hussain, Fernando Maia De Oliveira, Ranjitha Kumarapuram Hariharalakshmanan, Gregory Guisbiers, Tansel Karabacak

Faculty Scholarship

Tellurium has a unique helical crystal arrangement and pronounced anisotropy that influence its electronic and optical properties at the nanoscale. This study reports the synthesis of pure tellurium quantum dots (Te QDs) on silicon wafer using glancing angle deposition (GLAD). Quasi-hemispherical dots with lateral sizes ranging from 9 to 28 nm and vertical dimensions of 6 to 10 nm were produced as a function of the deposition duration. A comparison of the dot sizes with the Bohr radii of the charge carriers indicated a regime of strong to intermediate confinement. Structural analyses confirmed the polycrystalline nature and trigonal phase of …

Draft Butte Priority Soils Operable Unit (Bpsou) Silver Bow Creek Conservation Area (Sbcca) Operations And Maintenance (O&M) Plan, Stantec Consulting Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Exploring The Significance Of Kenya's Indigenous And Emerging Blue Foods For Sustainable Aquaculture Development. A Review, Jonathan Munguti, Mavindu Muthoka, Domitila Kyule, Esther Magondu, Kevin Obiero, Jimmy Mboya, Menaga Meenakshisundaram, Tanga M. Chrysantus, Gerald Kwikiriza, Francis K. Njonge

All Peer-Reviewed Publications

Kenya's aquaculture sector is at a pivotal stage, transitioning from a historical reliance on Nile tilapia and African catfish toward a more diversified production portfolio that integrates indigenous and emerging freshwater and marine species. This shift is increasingly recognized as essential to enhance climate resilience, food security, and ecosystem health. This systematic review synthesizes more than two decades (2000 to 31st January, 2026) of peer-reviewed literature to evaluate the biological suitability, culture performance, and socio-ecological roles of underutilized native taxa, including Ningu (Labeo victorianus), Jipe tilapia (Oreochromis jipe), freshwater prawns (Macrobrachium spp.), rabbitfish (Siganus sutor), marine-acclimatized Nile tilapia, mud crab …

Ph-Compensated Hydrogen Peroxide Quantification Using A Dual-Modal Fiber-Optic Probe, Homayoon Soleimani Dinani, Bohong Zhang, Maryam Karimi, Rex E. Gerald, Shelley D. Minteer, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

We report a dual-modal fiber-optic probe that integrates electrochemical quantification of hydrogen peroxide (H₂O₂) with co-localized fluorescent pH sensing for pH-indexed interpretation of the H₂O₂ response. H₂O₂ is a reactive oxygen species involved in oxidative stress, inflammation, and cellular signaling, and local pH modulates both its production and electrochemical response. Many electrochemical H₂O₂ sensors exhibit pH-dependent sensitivity, creating ambiguity unless pH is measured and used for compensation, which is difficult in small, heterogeneous, or rapidly changing microenvironments. A three-electrode configuration—working (WE), counter (CE), and Ag/AgCl pseudo-reference (pRE) electrodes—is fabricated directly on the cylindrical surface of a 710-µm-diameter optical fiber using …

Quality Assurance Project Plan - Spokane River Pfas Study, Chad Pritchard

EWU PFAS Research Collection

Assessing the impacts of poly- and perfluoroalkyl substances (PFAS) contamination across multiple aquifers and multiple sources requires a detailed understanding of the hydrogeologic framework to quantifiably determine PFAS sources. The West Plains of eastern Washington is an ideal natural laboratory to study the fate and transport of PFAS because the general geohydrologic framework has been established and collaboration with several related PFAS projects will maximize the use of grant funds. This project will help the population, environment, and commercial entities of the West Plains by building a transport model, delineating PFAS contamination, and using unique PFAS distribution at different locations …

Representation Stability In The Intrinsic Hyperplane Arrangements Associated To Irreducible Representations Of The Symmetric Groups, Ian Flynn, Eric Ramos, Benjamin Young

Mathematics and Statistics Faculty Publications and Presentations

Some of the most classically relevant Hyperplane arrangements are the Braid Arrangements Bn and their associated compliment spaces Fn. In their recent work, Tsilevich, Vershik, and Yuzvinsky [TVY20] construct what they refer to as the intrinsic hyperplane arrangement within any irreducible representation of the symmetric group that generalize the classical braid arrangements. Through examples it is also shown that the associated compliment spaces to these intrinsic arrangements display behaviors far removed from Fn. In this work we study the intrinsic hyperplane arrangements of irreducible representations of the symmetric group from the perspective of representation stability. This work is both theoretical, …

Mutation-Based Multi-Agent Test Case Update, Dawei Tian, Jiakun Liu, Yun Peng, Yichen Zhang, Jianlei Chi, Jun Sun, Xiaohong Su

Research Collection School Of Computing and Information Systems

Modern software systems evolve rapidly under CI/CD practices, where tests are critical for quality. However, substantial code changes often render existing test cases obsolete, causing pipeline disruptions, reduced productivity, and compromised quality. Recent automatic test update approaches leverage LLMs to refine test cases via execution feedback and exact-matching context retrieval, prioritizing executability and line coverage but suffering three limitations: (1) neglecting test assertion adequacy, weakening fault detection; (2) relying on coarse line coverage instead of specific uncovered lines/branches; (3) using exact-matching retrieval, which fails for LLM hallucinated queries. To address these, we propose MuMuTestUp, a mutation-guided multi-agent framework with three …

Ddor: Delta Debugging For Explainable Overrefusal Testing And Repair, Qinyan Zhou, Peixin Zhang, Jun Sun, Haonan Zhang, Dongxia Wang

Research Collection School Of Computing and Information Systems

While safety alignment and guardrails help large language models (LLMs) avoid harmful outputs, they can also induce overrefusal, i.e., unwarranted rejection of benign queries that merely appear risky. We present DDOR (Delta Debugging for OverRefusal), a fully automated and explainable framework for overrefusal testing and repair in a black-box setting, where only model inputs and outputs are accessible and internal safety mechanisms remain opaque. DDOR applies delta debugging to localize minimal refusal-triggering fragments (mRTFs) that provide phrase-level, explainable evidence for why a refusal occurs. Conditioned on these mRTFs, DDOR generates diverse, context-rich prompts and performs multi-oracle validation to filter intrinsically …

Characterizing And Repairing Obsolete Android Gui Tests Under Ui Evolution, Shiwen Song, Yiheng Xiong, Wenbo Guo, Manqi Sun, Jiaolong Kong, Xiaofei Xie

Research Collection School Of Computing and Information Systems

Graphical user interface (GUI) tests are widely used in regression testing of mobile applications (apps) tovalidate app behavior from the user’s perspective. However, frequent app evolution, such as UI redesignsand feature updates, often renders existing GUI tests obsolete, even when underlying functionality remainsunchanged. Automatically repairing such tests is critical for maintaining test suites and reducing substantialmanual effort. Despite the practical importance, there is still a lack of a systematic understanding of thecharacteristics of obsolete GUI tests and a publicly available benchmark to support their study. To fill thisgap, we construct a benchmark comprising 736 obsolete GUI tests collected from 36 …

Probguard: Proactive Runtime Monitoring For Llm Agent Safety Via Probabilistic Prediction, Haoyu Wang, Christopher M. Poskitt, Jiali Wei, Jun Sun

Research Collection School Of Computing and Information Systems

Large Language Model (LLM) agents increasingly operate across domains such as robotics, virtual assistants, and web automation. However, their stochastic decision-making introduces safety risks that are difficult to anticipate during execution. Existing runtime monitoring frameworks, such as AgentSpec, primarily rely on reactive safety rules that detect violations only when unsafe behavior is imminent or has already occurred, limiting their ability to handle long-horizon dependencies. We present ProbGuard, a proactive runtime monitoring framework for LLM agents that anticipates safety violations through probabilistic risk prediction. ProbGuard abstracts agent executions into symbolic states and learns a Discrete-Time Markov Chain (DTMC) from execution traces …

Mg-Fuzz: Model-Guided Fuzzing For Unsafe Scenario Discovery In Autonomous Driving Systems, Yulong Lyu, Ruiqi Hong, Jiawan Wang, Jun Sun, Lei Bu

Research Collection School Of Computing and Information Systems

As autonomous driving systems (ADS) are increasingly deployed in real-world environments, discovering diverse unsafe driving scenarios remains a fundamental yet difficult problem. Existing scenario generation and testing approaches often rely on black-box exploration or externally-observed heuristic feedback, which struggle to effectively guide the search toward high-risk scenarios induced by complex decision-making behaviors. A key difficulty stems from the fact that unsafe behaviors in ADS often arise from internal decision-making logic, which can induce structured and discontinuous responses that are hard to effectively explore using purely black-box guidance. Consequently, current tools tend to repeatedly discover a narrow set of similar unsafe …

Chatgpt, Can You Generate Multiple-Choice Questions For An Undergraduate Computing Course? An Evaluation Of Its Effectiveness Using Classical Test Theory, Eng Lieh Ouh, Kar Way Tan, Siaw Ling Lo, Benjamin Gan, Yuhao Zhang

Research Collection School Of Computing and Information Systems

Educators are increasingly adopting large language models such as ChatGPT to generate multiple-choice questions (MCQs), yet empirical evidence on the quality of these items in computing education assessments remains limited. This study compares 30 ChatGPT-generated and 30 manually crafted items from an undergraduate software design course, and evaluates item difficulty, discrimination, and distractor quality using Classical Test Theory. We triangulated two evaluations using within-subjects and between-subjects designs. Our quantitative findings show that all three metrics in both evaluations point in the same direction. ChatGPT-generated items are easier, less discriminating, and exhibit poorer distractor quality than manually crafted items. Distractor quality …

Resource Assessment Report No. 10: Southern Nearshore And Estuarine Scalefish Resource: Sandy Sprat (Whitebait) 2026 Assessment, Daniel E. Yeoh, Brett Crisafulli, Rubie Evans-Powell, Sybrand A. Hesp

Resource Assessment Reports

Sandy sprat Hyperlophus vittatus (‘whitebait’) is a small-bodied clupeid which occurs in temperate nearshore marine and estuarine waters throughout southern Australia. In Western Australia, this species is almost exclusively caught by the commercial sector on the lower west coast, between Perth and Geographe Bay, where it is considered to comprise a single biological stock. Since 2010, sandy sprat has primarily been caught by the South West Beach Net Fishery (SWBN) in the Bunbury region. This is a shore-based fishery which utilises beach seine nets to target a variety of finfish species in shallow nearshore waters.

Commercial catch is monitored and …

From Innovation To Impact: Evaluation Of The Shape Accelerator Cohort, Iryna V. Lendel, Chloe Wieber

Upjohn Institute Technical Reports

The Solutions Hub for an Alternative Packaging Ecosystem (SHAPE), a Michigan-Ohio partnership operated by the Michigan State University Research Foundation as part of a National Science Foundation Regional Innovation Engine, co-funded a special cohort of the NextCycle Accelerator focused on sustainable packaging and circular economy ventures. This report evaluates how the accelerator contributed to firm-level advancement and ecosystem-level change, drawing on program data and interviews with participating companies, program facilitators, stakeholders, and SHAPE management.  Participants most consistently credited coaching, network connections, and the Pitch Showcase with meaningfully impacting their business trajectory, gaining market traction, advancing technology readiness, and gaining access …

Quantum Mechanics, Non-Locality, And The Space Discreteness Hypothesis, Wilson A. Zuniga-Galindo

School of Mathematical & Statistical Sciences Faculty Publications

The space discreteness hypothesis asserts that the nature of space at short distances is radically different from that at large distances. Based on the Bronstein inequality, here, we use a totally disconnected topological space X as a model for the physical space at short distances. However, we consider the time as a real variable. In this framework, the Dirac–von Neumann formalism can be used. This discreteness hypothesis implies that given two different points in space, there is no continuous curve (a world line) joining them. Consequently, this hypothesis is not compatible with the theory of relativity. We propose R×(R×X)3 as …

Aidws1: Building With Llms And Ai Agent, Olivier Kepler Francois

Paul English Applied Artificial Intelligence (AI) Institute Publications

The Paul English Applied Artificial Intelligence Institute (PEAAII) at the University of Massachusetts Boston hosted the first session of its AI Demo Workshop Series, “Building with LLMs and AI Agents,” on October 5, 2026, led by Olivier Kepler Francois, Founder and Researcher of WebAIAgent. This hands-on workshop introduced participants to developing AI-powered web applications using Large Language Models (LLMs), Next.js, React, HTTP communication, and the OpenAI API. Through guided demonstrations and practical exercises, participants explored frontend and backend development, API integration, user interaction, and the end-to-end process of building an interactive AI application. The session provided foundational knowledge and practical …

Deflation-Based Preconditioning For Parallel Time Stepping Algorithms, Marina Nacianceno, Josef A. Sifuentes

School of Mathematical & Statistical Sciences Faculty Publications

Often, in solving large systems of differential equations using a time-stepping algorithm, one must solve multiple linear systems where the coefficient matrix is unchanged or shifted by a constant multiple of the identity. This can be computationally expensive when the coefficient matrix involved is very large. Where direct methods like Gaussian elimination are infeasible, iterative methods like GMRES are often used. It is especially useful when the matrices involved are sparse or allow for fast matrix multiplication algorithms. In this paper, we propose preconditioning strategies that glean information from previous runs of GMRES to build an effective preconditioner for subsequent …

Where Are Linearized Gauge Invariants Encoded For Plane Waves In Linearized Gravity, Ramesh Radhakrishnan, David Mcnutt, Delaram Mirfendereski, Eric Davis, William Julius, Gerald Cleaver

Physics & Astronomy Faculty Publications

In this work we will investigate the structures of invariants within the class of plane waves in linearized General Relativity, to introduce a new approach to determine the linearized gauge invariants encoding the polarization of the plane waves. The Newman–Penrose (NP) formalism is traditionally used to analyze the polarization content of gravitational waves, while the gauge-invariant Bardeen formalism provides a complementary description based on the irreducible scalar, vector, and tensor perturbations of the metric. We will apply the Bardeen formalism to compute all scalar, vector, and tensor gauge-invariant variables explicitly and verify that only the two transverse–traceless tensor modes survive. …

Aidws3: Stubborn And Hallucinating Agents, Inal Mashukov

Paul English Applied Artificial Intelligence (AI) Institute Publications

This workshop, part of the AI Demo Day Workshop Series hosted by the Paul English Applied AI Institute (PEAAII) at UMass Boston, explores the bias-variance tradeoff and how it affects the performance and reliability of AI models and agents. Led by Inal Mashukov, PhD Researcher at UMass Boston, the session covers concepts such as underfitting, overfitting, and regularization techniques to improve model performance. Through practical examples and hands-on exercises using PyTorch, participants explore why AI agents may hallucinate, repeat mistakes, or struggle to adapt, and learn approaches to building more reliable AI systems.

Evaluating The Nash Reaction As A Sustainable Alternative To The Snar Reaction In The Synthesis Of Pharmaceutical Intermediates, Allison L. Ryerson, James K. Bashkin, Jessica R. N. Thompson, Adam Weiss, Huy Q. Nguyen

Undergraduate Research Symposium

Nucleophilic aromatic substitution (SNAr) reactions are one of the most widely used reaction classes in pharmaceutical production today, used for example to produce nitroaryl amine intermediates. In comparison to the traditional SNAr pathway, the nucleophilic aromatic substitution of hydrogen (NASH) provides a greener alternative in pharmaceutical production by using cheaper starting materials, eliminating more hazardous solvents, and reducing toxic waste.

Synthesis And Charge Transport Characterization Of 9,9'-Bifluorenylidene-Based Conjugated Molecules For Single-Molecule Conductance, Zach Moughamian, Jahnavi Badiganti, Jinjia Xu

Undergraduate Research Symposium

Molecular electronics explores the use of individual molecules as functional components in nanoscale electronic devices. In this project, fluorenone-based π-conjugated molecules including 9,9'-bifluorenylidene-S and triphenylamine-substituted derivatives were synthesized to investigate structure-property relationships relevant to molecular charge transport. The synthesized compounds were obtained in 13% and 27% yield respectively. ¹H NMR spectroscopy confirms characteristic aromatic resonances in the 7-9 ppm region consistent with the conjugated framework. UV–Vis spectroscopy reveals absorption maxima at 459 nm and 470 nm, indicating extended π-conjugation and donor-acceptor effects. Single-crystal X-ray diffraction confirms the structure of 9,9'-bifluorenylidene-S, which crystallizes in the monoclinic system (space group P2₁/c). In …

Enantioselectivity Of The Photochemical Continuous-Flow Isomerization Of Humulones, Gregory M. Giovine, Trevor Smith, Bruce Hamper

Undergraduate Research Symposium

Humulones, the primary natural product present in the historically significant hop flower, represent a largely unexplored candidate for structure-based pharmaceutical design.  Showing promising biological activity as an anti-bacterial and anti-inflammatory agent, humulones are of interest both for their bioactive properties and for their long-established tolerability and natural abundance.  Humulones undergo a characteristic isomerization reaction, where the six-membered substituted phloroglucinol ring contracts to a five-membered ring isohumulone, under a variety of conditions, including those enabled by brewing conditions (thermal, metal-catalyzed) and by exposure to UV light.  Optimization of the photocatalyzed isomerization of n-humulone to n-isohumulone in flow conditions resulted in a …

Mapping St. Louis History: Slavery, Redlining, And The May 16th Tornado, Safa M. Altamimi, Aster Horbanova, Riley J. Bearden, Vivian B. Rhodes, Bridget Ragan

Undergraduate Research Symposium

For this project, our group members are traveling across St.Louis to areas that are affected by the May 16th tornado. We will be taking pictures and using ArcGIS survey123 to input data connecting the tornado to historical forces such as Redlining and Slavery. Using this data, we will be creating an ArcGIS StoryMap and presenting our findings.

Love And Artificial Intelligence: A Research Proposal, Bryanna M. Deatherage, Necdet Gurkan, Sandra J.E. Langeslag

Undergraduate Research Symposium

What happens when people fall in love with Artificial Intelligence (AI)? This study seeks to examine individuals who are in love with AI companions to gain a deeper insight in the cognitive and affective consequences. In addition, this study will examine the most effective forms of intervention regarding growing or reducing feelings of love toward AI. The first part of this study will be a questionnaire about the social and emotional impact of being in love with an AI companion. Three hundred participants will be recruited through online communities related to AI companions. The second part of this study will …

Butte Priority Soils Operable Unit Final Butte Priority Soils Operable Unit Insufficiently Reclaimed Sites Field Sampling And Investigation Plan: Bres No. 1503 – Hornet Addition, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Operations And Maintenance Report Grove Gulch Sedimentation Bay For Third Quarter 2026 And Post-Storm 09.22.26 Silver Bow Creek/Butte Area Npl Site – Butte Priority Soils Operable Unit Consent Decree-Civil Action No. Cv 89-039-Bu-She, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.