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Articles 991 - 1020 of 2730
Full-Text Articles in Physical Sciences and Mathematics
Metal Nanoparticles/Carbon Nanotube Modified Electrodes For Voltammetric Determination Of Boron, Lokman Li̇v, Zekerya Dursun, Nuri̇ Naki̇boğlu
Metal Nanoparticles/Carbon Nanotube Modified Electrodes For Voltammetric Determination Of Boron, Lokman Li̇v, Zekerya Dursun, Nuri̇ Naki̇boğlu
Turkish Journal of Chemistry
This study describes a sensitive and accurate voltammetric method for determination of boron using metal nanoparticles/carbon nanotube modified electrodes. The oxidation peak of Alizarin Red S (ARS) at -0.59 V in the boron-ARS complex formed in ammonium/ammonia buffer solution (pH 8.5) was evaluated as a response. The electrode modification conditions and experimental parameters affecting the peak height were optimized. The characteristics of modified electrodes were investigated using cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscope, energy dispersive X-ray spectroscopy, high resolution transmission electron microscopy, and X-ray photoelectron spectroscopy. The limits of detection (3s$_{y/x})$ and the analytical ranges for gold nanoparticles/carbon …
Design And Synthesis Of New Naphtho[2,1-$B$]Pyrano [2,3-$D$]Pyrimidinones Under Classical And Microwave Conditions, Maher Cherif, Mariem Debbabi, Sarra Chortani, Anis Romdhane, Hichem Ben Jannet
Design And Synthesis Of New Naphtho[2,1-$B$]Pyrano [2,3-$D$]Pyrimidinones Under Classical And Microwave Conditions, Maher Cherif, Mariem Debbabi, Sarra Chortani, Anis Romdhane, Hichem Ben Jannet
Turkish Journal of Chemistry
A fast and efficient method for the synthesis of naphthopyranopyrimidinones derivatives in excellent yields was developed through cyclocondensation reaction between previously prepared pyrimidinic hydrazides and some electrophilic species such as 2,4-pentanedione, 2,5-hexanedione, cyclic anhydrides, and phenylthioisocyanate under microwave irradiation. Compared to the conventional methods applied, it was found that better yields and shorter reaction times were achieved using microwave-assisted synthesis. Structures of all synthesized compounds were established on the basis of spectroscopic methods including $^{1}$H NMR, $^{13}$C NMR, and HRMS-ES.
Synergetic Effect Of Mn, Ce, Ba, And B Modification And Moderate Desilication Of Nanostructured Hzsm-5 Catalyst On Conversion Of Methanol To Propylene, Fatemeh Yahyazadeh Saravi, Majid Taghizadeh
Synergetic Effect Of Mn, Ce, Ba, And B Modification And Moderate Desilication Of Nanostructured Hzsm-5 Catalyst On Conversion Of Methanol To Propylene, Fatemeh Yahyazadeh Saravi, Majid Taghizadeh
Turkish Journal of Chemistry
Modified mesoporous HZSM-5 catalysts were prepared by controlled desilication using a mixture of NaOH and TPAOH (tetrapropylammonium hydroxide) and impregnation of metals (Mn, Ce, and Ba) and metalloid B. The catalytic performances of all prepared catalysts for methanol to propylene (MTP) reaction were evaluated in a fixed bed reactor under atmospheric pressure at 480 \textdegree C. The parent and modified catalysts were characterized by XRD, ICP-OES, FE-SEM, NH$_{3}$-TPD, FT-IR, BET, and TGA techniques. The catalyst loaded with 2 wt.% manganese on desilicated HZSM-5 demonstrated the best catalytic performance in terms of the highest selectivity of C$_{2}^{=}$ to C$_{4}^{=}$ olefins (about …
Synthesis And Antimicrobial And Antioxidant Activities Of Hybrid Molecules Containing Benzotriazole And 1,2,4-Triazole, Mahesh Chand, Reena Kaushik, Subhash Chand Jain
Synthesis And Antimicrobial And Antioxidant Activities Of Hybrid Molecules Containing Benzotriazole And 1,2,4-Triazole, Mahesh Chand, Reena Kaushik, Subhash Chand Jain
Turkish Journal of Chemistry
Eleven novel 1,2,4-triazolylbenzotriazoles have been prepared using 1-(hydrazinylcarbonylmethyl)-1$H$-benzot- riazole (3) as a potent intermediate. Compound 3, however, was obtained from benzotriazole in two steps. All synthesized compounds were characterized by detailed spectral studies like IR, $^{1}$H NMR, $^{13}$C NMR, and mass spectrometry. All synthesized compounds were evaluated for their \textit{in vitro} antimicrobial activity against seven strains of bacteria and four strains of fungi. Compounds 13, 17, 19, 20, and 21}were found to possess antibacterial activity comparable to that of ciprofloxacin against a Klebsiella pneumoniae strain. Except for compounds2 and 13, all compounds showed good antifungal activity against an Aspergillus niger …
Neutral Atoms And Ion Energies, Accurate Ionization Potential, And Electron Affinities By Polynomial Generator Coordinate Hartree--Fock Method, Fernando Ratuchne, Ricardo Celeste
Neutral Atoms And Ion Energies, Accurate Ionization Potential, And Electron Affinities By Polynomial Generator Coordinate Hartree--Fock Method, Fernando Ratuchne, Ricardo Celeste
Turkish Journal of Chemistry
We have developed accurate Gaussian basis functions obtained with the polynomial generator coordinate Hartree-Fock (p-GCHF) method for H, Zn, and Ga-Kr atoms. These basis sets have been applied in the calculation of nonrelativistic energies for neutral atoms, monovalent cations, monovalent anions, ionization potential (IP), and electron affinity (EA), with the objective of proving the quality of the basis set generated by the p-GCHF method. The total energies calculated for neutral atoms and monovalent cations and respective IP were minimally affected by the addition of polarization functions and their precision was comparable to the values reported in the literature. The relative …
Novel Optical Sensor-Based Method For Determining Total Tocopherol Content In Serum, Mustafa Bener, Mustafa Reşat Apak
Novel Optical Sensor-Based Method For Determining Total Tocopherol Content In Serum, Mustafa Bener, Mustafa Reşat Apak
Turkish Journal of Chemistry
Lipid-soluble endogenous antioxidants, such as tocopherols, protect biological structures from oxidative damage through their chain-breaking ability and thus the development of a simple method for tocopherol determination is important. In this study, a novel optical sensor-based method was proposed for determining total tocopherol content (TTC) of serum, with selectivity for $\alpha $-tocopherol over $\beta $-carotene. The proposed method is based on the use of a copper(II)-neocuproine complex (Cu(II)-Nc) reagent immobilized onto a Nafion membrane, and the absorbance changes associated with the formation of Cu(I)-Nc chelate on the membrane strip as a result of reaction with serum tocopherols were measured at …
Quantification Of Flavonoids Isolated From \Textit{Mentha Spicata} In Selected Clones Of Turkish Mint Landraces, Ramazan Erenler, İsa Telci̇, Mahfuz Elmastaş, Hüseyi̇n Akşi̇t, Fati̇h Gül, Ali̇ Riza Tüfekçi̇, İbrahi̇m Demi̇rtaş, Ömer Kayir
Quantification Of Flavonoids Isolated From \Textit{Mentha Spicata} In Selected Clones Of Turkish Mint Landraces, Ramazan Erenler, İsa Telci̇, Mahfuz Elmastaş, Hüseyi̇n Akşi̇t, Fati̇h Gül, Ali̇ Riza Tüfekçi̇, İbrahi̇m Demi̇rtaş, Ömer Kayir
Turkish Journal of Chemistry
Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world. Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mints landraces were achieved. M. spicata was dried in shade and then boiled in water. After filtration, the aqueous extract was partitioned with ethyl acetate. The solvent was removed under reduced pressure to yield the extract, subjected to silica gel column chromatography to isolate 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4), the structures of which were elucidated by 1D NMR, 2D NMR, and LC-TOF/MS. The isolated …
The Catalytic Effects Of In Situ Prepared N-Heterocyclic Carbenes From Benzimidazole Salts In Suzuki--Miyaura Cross-Coupling Reaction And Uses In Catalytic Preparation Of 1,3,5-Triphenyl-1,3,5-Triazinane-2,4,6-Trione From Phenyl Isocyanate, Ülkü Yilmaz, Hasan Küçükbay
The Catalytic Effects Of In Situ Prepared N-Heterocyclic Carbenes From Benzimidazole Salts In Suzuki--Miyaura Cross-Coupling Reaction And Uses In Catalytic Preparation Of 1,3,5-Triphenyl-1,3,5-Triazinane-2,4,6-Trione From Phenyl Isocyanate, Ülkü Yilmaz, Hasan Küçükbay
Turkish Journal of Chemistry
Many benzimidazole salts bearing a 3-phenylpropyl substituent (1a-1h) were synthesized and their structures were identified by $^{1}$H NMR, $^{13}$C NMR, and IR spectroscopic methods and elemental analysis. These N-heterocyclic carbene (NHC) precursors were used as a part of a catalytic system including Pd(OAc)$_{2}$ and the base in the Suzuki--Miyaura cross-coupling reaction under microwave irradiation. They were also used as catalysts in the cyclotrimerization of phenyl isocyanate to yield 1,3,5-triphenyl-1,3,5-triazinane-2,4,6-trione. It has been observed that benzimidazole salts made a positive contribution to both catalytic reactions as a NHC precursor.
Optimization Of Sugarcane Bagasse Activation To Achieve Adsorbent With High Affinity Towards Phenol, Seyed-Abolfazl Mohtashami, Neda Asasian Kolur, Tahereh Kaghazchi, Reza Asadi-Kesheh, Mansooreh Soleimani
Optimization Of Sugarcane Bagasse Activation To Achieve Adsorbent With High Affinity Towards Phenol, Seyed-Abolfazl Mohtashami, Neda Asasian Kolur, Tahereh Kaghazchi, Reza Asadi-Kesheh, Mansooreh Soleimani
Turkish Journal of Chemistry
Sugarcane bagasse as an agricultural/industrial biomass was converted into a low-cost activated carbon via an acid activation procedure under optimized conditions. Phosphoric acid was applied as a cost-effective and environmentally friendly chemical activator. The optimized activated carbon produced under temperature of 550 \textdegree C and impregnation ratio of 1.5 showed a micromesoporous structure with specific surface area and pore volume of 972.5 m$^{2}$/g and 0.43 cm$^{3}$/g, respectively. The adsorption capacity of the produced AC towards phenol was measured and, after only 30 min, the removal percentage reached over 95%. The greatest affinity towards phenol was obtained at pH of 4 …
Voltammetric Determination Of Glycopyrrolate In A Pharmaceutical Formulation, Muneer Fadr, Abdulaziz Nabil Amro, Sami Ben Aoun, Samer Ratrout, Fadi Asfour
Voltammetric Determination Of Glycopyrrolate In A Pharmaceutical Formulation, Muneer Fadr, Abdulaziz Nabil Amro, Sami Ben Aoun, Samer Ratrout, Fadi Asfour
Turkish Journal of Chemistry
The electrochemical activity of glycopyrrolate was studied. Different voltammetric techniques were applied in this study, including cyclic voltammetry (CV), differential pulse voltammetry (DPV), and linear sweep voltammetry (LSV). Glassy carbon and platinum working electrodes were utilized. CV indicated that glycopyrrolate has a reversible redox reaction on the working electrode surface, with an anodic peak current at approximately 1.05 V and a cathodic peak at 0.80 V. Several parameters that affect the sensitivity of these methods were optimized for the quantitation of glycopyrrolate. LSV showed a better correlation coefficient than DPV did, with a value of ca. 0.9990 in the range …
Preparation Of Self-Propelled Cu-Pt Micromotors And Their Application In Mirna Monitoring, Lütfi̇ Öksüz, Gözde Yurdabak Karaca, Fi̇li̇z Kuralay, Emre Uygun, İsmi̇han Ümran Koç, Ayşegül Uygun Öksüz
Preparation Of Self-Propelled Cu-Pt Micromotors And Their Application In Mirna Monitoring, Lütfi̇ Öksüz, Gözde Yurdabak Karaca, Fi̇li̇z Kuralay, Emre Uygun, İsmi̇han Ümran Koç, Ayşegül Uygun Öksüz
Turkish Journal of Chemistry
Self-propelled catalytic micromotors offer considerable promise in terms of many applications. Catalytic micromotors are strongly influenced by the presence and concentration of specific ions and chemicals in the environment, making them useful as sensors and actuators. In this work, copper (Cu)-platinum (Pt) micromotors were fabricated by using the magnetron sputtering method for the first time in the literature and their applications based on the detection of miRNA-21 were evaluated. We analyzed the dependence of the mobility of Cu-Pt micromotors using different concentrations of hydrogen peroxide (H$_{2}$O$_{2})$. The presence of surfactants in the environment is also important for the movement of …
Determination Of Hydrogen Peroxide With An Enzymeless Amperometric Sensor Based On Poly(Vinylferrocene)-Supported Ag Nanoparticles, Mutlu Sönmez Çelebi̇, Kübra Öztürk, Mehmet Dumangöz, Fi̇li̇z Kuralay
Determination Of Hydrogen Peroxide With An Enzymeless Amperometric Sensor Based On Poly(Vinylferrocene)-Supported Ag Nanoparticles, Mutlu Sönmez Çelebi̇, Kübra Öztürk, Mehmet Dumangöz, Fi̇li̇z Kuralay
Turkish Journal of Chemistry
An enzymeless electrochemical sensor for detection of low amounts of H$_{2}$O$_{2}$ with the aid of Ag nanoparticles supported on conducting poly(vinylferrocene) (PVF) film was developed. Experimental results revealed that contribution of Ag nanoparticles led to remarkable improvement by means of reduction potential and reduction current. Influence of experimental parameters (i.e. polymeric film thickness, concentration of Ag precursor, immersion time in precursor solution, reduction time, and reduction potential) were investigated. The Ag/PVF-modified electrode system was characterized physically by scanning electron microscopy. The results revealed that the sensor developed was easy-to-prepare, economic, selective, and sensitive, with a fast response time of 3 …
Experimental And Theoretical Study Of Nh$_{3}$ Adsorption And Desorption Over A Cu-Chabazite Nh$_{3}$-Scr Catalyst, Selmi̇ Eri̇m Bozbağ, Mutlu Şi̇mşek, Onur Demi̇r, Deni̇z Şanli Yildiz, Hüseyi̇n Barkin Özener, Gökhan Hi̇sar, Can Erkey
Experimental And Theoretical Study Of Nh$_{3}$ Adsorption And Desorption Over A Cu-Chabazite Nh$_{3}$-Scr Catalyst, Selmi̇ Eri̇m Bozbağ, Mutlu Şi̇mşek, Onur Demi̇r, Deni̇z Şanli Yildiz, Hüseyi̇n Barkin Özener, Gökhan Hi̇sar, Can Erkey
Turkish Journal of Chemistry
NH$_{3}$ adsorption and desorption behavior of a commercial Cu-chabazite (CHA) NH$_{3}$ selective catalytic reduction (NH$_{3}$-SCR) catalyst was studied in the presence and absence of H$_{2}$O. NH$_{3}$ uptake values at various adsorption temperatures were obtained during various steps of the adsorption and temperature-programmed desorption (TPD) experiments. Total NH$_{3}$ uptake decreased from 4.6 to 1.6 g NH$_{3}$/L catalyst when the adsorption temperature was increased from 50 to 300 $^{\circ}$C. Three major adsorption sites for NH$_{3}$ adsorption could be identified and quantified using TPD experiments, namely loosely, moderately, and strongly bound NH$_{3}$ with peak centers at around 147, 266, and 447 $^{\circ}$C. The …
Application Of The Taguchi Approach To Optimize Zno Synthesis Via Hydrothermally Assisted Sol-Gel Method, Zahra Khaghanpour, Sanaz Naghibi
Application Of The Taguchi Approach To Optimize Zno Synthesis Via Hydrothermally Assisted Sol-Gel Method, Zahra Khaghanpour, Sanaz Naghibi
Turkish Journal of Chemistry
ZnO powder was synthesized via a hydrothermally assisted sol-gel method. Synthesis variables including Zn-precursor type, pH value, time, and temperature of hydrothermal treatment were analyzed using the Taguchi approach. The experimental procedures were defined based on the L9 array for four variables in three levels. The influences of those variables on the response parameters, i.e. crystallite size, crystallinity, band gap energy ($E_{g})$, and degradation constants ($k)$, were evaluated. XRD results and $E_{g}$ values showed that ZnO wurtzite appeared to be the only crystalline phase in the samples. Taguchi analysis predicted that the optimized conditions to achieve the highest photoactivity are …
Syntheses And Characterizations Of Cyclotriphosphazenes Containing A 4-Oxy-1-Naphthaldehyde Group, Hani̇fe İbi̇şoğlu, Esra Tanriverdi̇ Eçi̇k, Gönül Yeni̇lmez Çi̇ftçi̇
Syntheses And Characterizations Of Cyclotriphosphazenes Containing A 4-Oxy-1-Naphthaldehyde Group, Hani̇fe İbi̇şoğlu, Esra Tanriverdi̇ Eçi̇k, Gönül Yeni̇lmez Çi̇ftçi̇
Turkish Journal of Chemistry
The nucleophilic substitution reaction of hexachlorocyclotriphosphazene (N$_{3}$P$_{3}$Cl$_{6}$, trimer) (1) with 4-hydroxy-1-naphthaldehyde (2) has been investigated for the first time. 4$^{{\prime}} $-Oxy-1$^{{\prime}} $-naphthaldehyde substituted mono- (3), bis- (4), and tris- (5) cyclotriphosphazenes were obtained from the nucleophilic substitution of compound 1 with 2 in a 1:2 molar ratio in the presence of Cs$_{2}$CO$_{3}$ in acetone at reflux. The pentakis-(6) and hexakis-substituted (7) cyclotriphosphazenes were prepared from the reaction of 1 with 2 in a 1:7 molar ratio using K$_{2}$CO$_{3}$ as a proton abstractor in tetrahydrofuran at room temperature. The structures of the new compounds (3-7) were determined by elemental analysis, FT-IR, …
The Interaction Between A Zinc(Ii) Phthalocyanine Compound Bearing Octakis Phenoxyacetamide Substituents And Calf Thymus Dna, Ali̇ Arslantaş, Mehmet Sali̇h Ağirtaş
The Interaction Between A Zinc(Ii) Phthalocyanine Compound Bearing Octakis Phenoxyacetamide Substituents And Calf Thymus Dna, Ali̇ Arslantaş, Mehmet Sali̇h Ağirtaş
Turkish Journal of Chemistry
In this study, a zinc(II) phthalocyanine compound (PcZn) substituted with octakis phenoxyacetamide was synthesized and characterized. Calf thymus DNA (CT-DNA) was used to determine the DNA binding properties of the zinc(II) phthalocyanine compound. This interaction of CT-DNA with PcZn was investigated using electronic absorption spectra, emission spectroscopy, a thermal melting temperature study, cyclic voltammetry, and viscosity measurements in a Tris-HCl buffer solution at a pH of 7.2. The findings showed that zinc(II) phthalocyanine interacts with calf thymus DNA via partial intercalative binding mechanisms. In addition to the techniques above, a gel electrophoresis study was also carried out to verify the …
Synthesis Of Acetamide Derivatives Of 1,2,4-Triazole Bearing Azinane And Their Binding Interactions With Bovine Serum Albumin Using Spectroscopic Techniques, Javed Iqbal, Aziz Ur Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Hira Khalid, Sabina Jhaumeer Laulloo, Nausheen Joondan, Aniisah Banu Taupass, Shahid Rasool, Syed Adnan Ali Shah
Synthesis Of Acetamide Derivatives Of 1,2,4-Triazole Bearing Azinane And Their Binding Interactions With Bovine Serum Albumin Using Spectroscopic Techniques, Javed Iqbal, Aziz Ur Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Hira Khalid, Sabina Jhaumeer Laulloo, Nausheen Joondan, Aniisah Banu Taupass, Shahid Rasool, Syed Adnan Ali Shah
Turkish Journal of Chemistry
A new series of acetamide derivatives containing 1,2,4-triazole and azinane moieties has been synthesized and characterized using $^{1}$H NMR, $^{13}$C NMR, IR, and EI-MS spectroscopic analysis. The intermediate triazole was synthesized through a sequential synthesis of carboxylate and carbohydrazide. The bovine serum albumin (BSA) binding of the newly synthesized 1,2,4-triazole derivatives was evaluated along with thermodynamics, site-selective binding, and synchronous study. The results obtained by BSA binding as well as thermodynamic studies justify that all the compounds show spontaneous interaction with BSA and could be effectively distributed and eliminated from the body. Therefore, the triazole-based analogs might be a useful …
Recent Advances In Thymidine Phosphorylase Inhibitors: Syntheses And Prospective Medicinal Applications, Muhammad Aamir Sajid, Zulfiqar Ali Khan, Sohail Anjum Shahzad, Syed Ali̇ Raza Naqvi, Muhammad Usman, Ahsan Iqbal
Recent Advances In Thymidine Phosphorylase Inhibitors: Syntheses And Prospective Medicinal Applications, Muhammad Aamir Sajid, Zulfiqar Ali Khan, Sohail Anjum Shahzad, Syed Ali̇ Raza Naqvi, Muhammad Usman, Ahsan Iqbal
Turkish Journal of Chemistry
This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.
N-Heterocyclic Carbenes Bearing A Naphthyl Substituent And Their Metal Complexes: Synthesis, Structure, And Application In Catalytic Transfer Hydrogenation, Ayli̇n Ati̇k, Lütfi̇ye Gök Pezük, Hayati̇ Türkmen
N-Heterocyclic Carbenes Bearing A Naphthyl Substituent And Their Metal Complexes: Synthesis, Structure, And Application In Catalytic Transfer Hydrogenation, Ayli̇n Ati̇k, Lütfi̇ye Gök Pezük, Hayati̇ Türkmen
Turkish Journal of Chemistry
A series of unsymmetrical imidazolinium bromides (3a-d) bearing naphthyl and benzyl groups (R' = CH$_{2}$C$_{6}$H$_{2}$(CH$_{3})_{3}$-2,4,6 (a); CH$_{2}$C$_{6}$H(CH$_{3})_{4}$-2,3,5,6 (b); CH$_{2}$C$_{6}$(CH$_{3})_{5}$ (c); CH$_{2}$C$_{6}$F$_{5\, }$(d)) at the N$^{1}$ and N$^{3}$ positions were successfully synthesized. [RuCl$_{2}$(NHC)($p$-cymene)] (NHC= N-heterocyclic carbene) complexes (4a-d) were prepared by the reaction of [RuCl$_{2}(p$-cymene)]$_{2}$ with imidazolinium salts (3a-d). The new salts (3a-d) and their ruthenium(II) complexes (4a-d) were characterized by $^{1}$H, $^{13}$C, $^{19}$F NMR, and elemental analysis. The ruthenium(II) complexes (4a-d) were employed as catalysts for the transfer hydrogenation (TH) of ketones in the presence of KOH using 2-propanol as a hydrogen source and the results were compared. The best …
Electrochemical Detection Of Dna Interaction With Mannich Base Derivatives By Disposable Graphite Electrodes, Hüseyi̇n İstanbullu, Hakan Karadeni̇z, Erçi̇n Erci̇yas, Kadri̇ye Arzum Erdem Gürsan
Electrochemical Detection Of Dna Interaction With Mannich Base Derivatives By Disposable Graphite Electrodes, Hüseyi̇n İstanbullu, Hakan Karadeni̇z, Erçi̇n Erci̇yas, Kadri̇ye Arzum Erdem Gürsan
Turkish Journal of Chemistry
Four different Mannich base derivatives containing an aromatic/heteroaromatic propanone structure (C1 (3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride); C2 (3-morpholino-1-(pyridin-3-yl)propan-1-one hydrochloride); C3 (3-(dimethylamino)-1-(1H-indol-3-yl)propan-1-one hydrochloride), C4 (3-(piperidin-1-yl)-1-(pyren-1-yl)propan-1-one hydrochloride)) were earlier synthesized and characterized with $^{1}$H NMR, $^{13}$C NMR, MS, and elemental analysis. The interaction of these compounds with fish sperm double stranded DNA (fs-dsDNA) was investigated by using differential pulse voltammetry (DPV) in connection with a disposable pencil graphite electrode (PGE). After the interaction procedure, there was a meaningful decrease in the oxidation signal of the electroactive DNA base guanine due to possible intercalation and/or alkylation mechanism between these Mannich base derivatives and DNA. The features …
Investigation Of The Effects Of Purification And Characterization Of Turkey (Meleagris Gallopavo) Liver Mitochondrial Thioredoxin Reductase Enzyme And Some Metal Ions On Enzyme Activity, Yusuf Temel, Ö. İrfan Küfrevi̇oğlu, Mehmet Çi̇ftci̇
Investigation Of The Effects Of Purification And Characterization Of Turkey (Meleagris Gallopavo) Liver Mitochondrial Thioredoxin Reductase Enzyme And Some Metal Ions On Enzyme Activity, Yusuf Temel, Ö. İrfan Küfrevi̇oğlu, Mehmet Çi̇ftci̇
Turkish Journal of Chemistry
The thioredoxin system, found in all living creatures, consists of thioredoxin protein (Trx), thioredoxin reductase enzyme (TrxR), and NADPH. In this study, turkey liver mitochondrial TrxR enzyme with 3.07 EU $\times $ mg$^{-1}$ specific activity was purified 990-fold in a yield of 2.05{\%} using 2',5'-ADP Sepharose 4B affinity chromatography. The purity of the enzyme was measured and the molecular weight of its subunits was determined to be 45.5 kDa by SDS-PAGE. The molecular mass of the enzyme's natural state was found to be 88 kDa using Sephadex-G 150 gel filtration chromatography. In addition, characteristic and kinetic properties of the enzyme …
Supramolecular Solvent Microextraction Of Uranium At Trace Levels From Water And Soil Samples, Mansoor Khan, Erkan Yilmaz, Mustafa Soylak
Supramolecular Solvent Microextraction Of Uranium At Trace Levels From Water And Soil Samples, Mansoor Khan, Erkan Yilmaz, Mustafa Soylak
Turkish Journal of Chemistry
A supramolecular solvent microextraction procedure was established for the separation/preconcentration of uranium(VI) (U(VI)) prior to its determination by UV-Vis spectrophotometry. 1-(2-Pyridylazo)-2-naphthol (PAN) was used to form a red chelate (U-PAN) with U(VI) at pH 10. U-PAN was extracted by undecanol in tetrahydrofuran. All the parameters that affect extraction efficiency like solution pH, amount of ligand, type and volume of supramolecular solvent, sample volume, and diverse ion effect were optimized. The preconcentration factor was 17. The detection limit was 0.31 $\mu $g L$^{-1}$. The method was validated using GBW07424 (GSS-10 certified reference material). Microextraction was also applied to water and soil …
Graphite Oxide Catalyzed Synthesis Of $\Beta $-Amino Alcohols By Ring-Opening Of Epoxides, Maryam Mirza-Aghayan, Farzaneh Alvandi, Mahdieh Molaee Tavana, Rabah Boukherroub
Graphite Oxide Catalyzed Synthesis Of $\Beta $-Amino Alcohols By Ring-Opening Of Epoxides, Maryam Mirza-Aghayan, Farzaneh Alvandi, Mahdieh Molaee Tavana, Rabah Boukherroub
Turkish Journal of Chemistry
Graphite oxide as a heterogeneous and recyclable solid acid catalyzed a simple and efficient method for the synthesis of $\beta $-amino alcohols by ring opening of epoxides with amines. This method is effective with various aromatic and aliphatic amines under solvent-free conditions. The corresponding $\beta $-amino alcohols are obtained in high yields (56%-95%) and short reaction times (15-30 min) with high regio- and chemoselectivity under metal-free conditions.
Synthesis And Antifungal Activity Of New Dihydrofurocoumarins And Dihydrofuroquinolines, Asli Ustalar, Mehmet Yilmaz, Agi̇m Osmani̇, Sema Aşkin Keçeli̇
Synthesis And Antifungal Activity Of New Dihydrofurocoumarins And Dihydrofuroquinolines, Asli Ustalar, Mehmet Yilmaz, Agi̇m Osmani̇, Sema Aşkin Keçeli̇
Turkish Journal of Chemistry
We investigated the radical addition of 4-hydroxycoumarin (1a) and 4-hydroxyquinoline (1b) with conjugated dienes ({2a-f) mediated by cerium(IV) ammonium nitrate (CAN) resulting in ethenyl substituted 2,3-dihydrofurocoumarin (3a-f) and 3,5-dihydrofuroquinoline (3g, 3h) compounds in moderate to good yields. All compounds were characterized by spectroscopic methods (IR, MS, and $^{1}$H and $^{13}$C NMR) and microanalysis. Antifungal activities of these compounds were investigated against the fungi Candida albicans, C. parapsilosis, C. krusei, C. glabrata, C. tropicalis, and Aspergillus fumigatus.
Highly Selective Schiff Base Derivatives For Colorimetric Detection Of Al$^{3+}$, Zi̇ya Aydin, Mustafa Keleş
Highly Selective Schiff Base Derivatives For Colorimetric Detection Of Al$^{3+}$, Zi̇ya Aydin, Mustafa Keleş
Turkish Journal of Chemistry
Schiff base derivatives NBAR and NSAR were developed for selective detection of Al$^{3+}$ in aqueous solution. UV-vis spectroscopic studies revealed that NBAR and NSAR showed marked sensitivity and selectivity to Al$^{3+}$ in acetonitrile (ACN)/water (v/v, 1:1, pH 6.80). The NBAR and NSAR receptors bound Al$^{3+}$ in a 2:1 stoichiometry with apparent binding constants 4.09 $\times $ 10$^{11}$ M$^{-2}$ and 1.65 $\times $ 10$^{12}$ M$^{-2}$, respectively. They also displayed distinct changes in color upon the alteration of free Al$^{3+}$ levels in solution with reversible responses and showed little interference with other metal ions.
Sonochemical Degradation Of Basic Red 29 In Aqueous Media, Zineb Boutamine, Slimane Merouani, Oualid Hamdaoui
Sonochemical Degradation Of Basic Red 29 In Aqueous Media, Zineb Boutamine, Slimane Merouani, Oualid Hamdaoui
Turkish Journal of Chemistry
In this work, the degradation of Basic Red 29 (BR29), an azo dye, was investigated using a high-frequency ultrasonic reactor (300 kHz). The influence of several parameters such as initial substrate concentration (5--200 mg L$^{-1})$, pH (3-10.1), ultrasonic power (20-80 W), and nature of the dissolved gas (Ar, air, and N$_{2})$ on the degradation of BR29 was assessed. Additionally, the impact of natural matrices (seawater and natural and river waters) on the degradation rate of BR29 was clarified. Degradation experiments with radical scavengers, tert-butyl alcohol and glucose, showed that BR29 degraded mainly through HO$^{\bullet }$ radical attack at the gas/liquid …
Voltammetric Analysis Of Disulfiram In Pharmaceuticals With A Cyclic Renewable Silver Amalgam Film Electrode, Sylwia Smarzewska, Natalia Festinger, Monika Skowron, Dariusz Guziejewski, Radovan Metelka, Mariola Brycht, Witold Ciesielski
Voltammetric Analysis Of Disulfiram In Pharmaceuticals With A Cyclic Renewable Silver Amalgam Film Electrode, Sylwia Smarzewska, Natalia Festinger, Monika Skowron, Dariusz Guziejewski, Radovan Metelka, Mariola Brycht, Witold Ciesielski
Turkish Journal of Chemistry
Electrochemical properties of disulfiram, representative of highly significant bioactive compounds, were studied with a cyclic renewable silver amalgam film electrode (Hg(Ag)FE) using square wave cathodic stripping voltammetry (SWCSV). The influence of various factors such as pH, buffer concentration, buffer composition, and SWCSV parameters on current response was investigated. The optimum results in terms of signal shape and intensity were recorded in Britton--Robinson buffer (pH 7.5) at -0.5 V versus Ag/AgCl/3 mol L$^{-1}$ KCl. An elaborated electroanalytical procedure was used to determine disulfiram at the Hg(Ag)FE in the concentration range from 0.05 to 5.00 $\mu $M. Precision, repeatability, and accuracy of …
Synthesis And Cytotoxicity Of Novel Thioxo-Quinazolino[3,4-$A$]Quinazolinones, Negar Mohammadhosseini, Mina Saeedi, Shahram Moradi, Mohammad Mahdavi, Omidreza Firuzi, Alireza Foroumadi, Abbas Shafiee
Synthesis And Cytotoxicity Of Novel Thioxo-Quinazolino[3,4-$A$]Quinazolinones, Negar Mohammadhosseini, Mina Saeedi, Shahram Moradi, Mohammad Mahdavi, Omidreza Firuzi, Alireza Foroumadi, Abbas Shafiee
Turkish Journal of Chemistry
Various thioxo-quinazolino[3,4-$a$]quinazolinones were prepared and evaluated for their cytotoxicity in MOLT-4 (lymphoblastic leukemia) and MCF-7 (breast adenocarcinoma) cell lines. Synthesis of the target compounds was started from isatoic anhydride. Successive reaction of isatoic anhydride with benzylamine and 2-nitrobenzaldehyde, reduction of the nitro group, and reaction with CS$_{2}$ gave 12-benzyl-6-thioxo-6,7,11b,12-tetrahydro-13$H$-quinazolino[3,4-$a$]quinazolin-13-one. The latter compound reacted with various 2-chloro-$N$-substituted acetamides to afford the corresponding fused quinazolinone derivatives.
Synthesis And Characterization Of Magnetic Amidoximated Chitosan-G Poly(Polyacrylonitrile)/Laponite Rd Nanocomposites With Enhanced Adsorption Capacity For Cu$^{2+}$, Gholam Reza Mahdavinia, Ebrahim Shokri
Synthesis And Characterization Of Magnetic Amidoximated Chitosan-G Poly(Polyacrylonitrile)/Laponite Rd Nanocomposites With Enhanced Adsorption Capacity For Cu$^{2+}$, Gholam Reza Mahdavinia, Ebrahim Shokri
Turkish Journal of Chemistry
Magnetic amidoximated nanocomposites based on a combination of chitosan and magnetic laponite RD were prepared and examined for the removal of Cu$^{2+}$ from aqueous solutions. Magnetic laponite RD was prepared by an in situ method. In order to prepare magnetic amidoximated nanocomposites, acrylonitrile was grafted to chitosan in the presence of magnetic laponite RD. Then the nitrile pendants on magnetic chitosan-g-polyacrylonitrile/laponite RD (mChtioPANLap) were converted to amidoxime groups. We developed a polyamidoximated magnetic nanocomposite based on a mixture of chitosan/laponite RD, possessing a high adsorption capacity for Cu$^{2+}$. By introducing magnetic laponite RD the adsorption capacity of nanocomposites for Cu$^{2+}$ …
Isocoumarins And 3,4-Dihydroisocoumarins, Amazing Natural Products: A Review, Aisha Saddiqa, Osman Çakmak, Muhammad Usman
Isocoumarins And 3,4-Dihydroisocoumarins, Amazing Natural Products: A Review, Aisha Saddiqa, Osman Çakmak, Muhammad Usman
Turkish Journal of Chemistry
The isocoumarins are naturally occurring lactones that constitute an important class of natural products exhibiting an array of biological activities. A wide variety of these lactones have been isolated from natural sources and, due to their remarkable bioactivities and structural diversity, great attention has been focused on their synthesis. This review article focuses on their structural diversity, biological applications, and commonly used synthetic modes.