Physical Sciences and Mathematics Commons^™

Using Materialized Views For Answering Graph Pattern Queries, Michael Lan

Dissertations

Discovering patterns in graphs by evaluating graph pattern queries involving direct (edge-to-edge mapping) and reachability (edge-to-path mapping) relationships under homomorphisms on data graphs has been extensively studied. Previous studies have aimed to reduce the evaluation time of graph pattern queries due to the potentially numerous matches on large data graphs.

In this work, the concept of the summary graph is developed to improve the evaluation of tree pattern queries and graph pattern queries. The summary graph first filters out candidate matches which violate certain reachability constraints, and then finds local matches of query edges. This reduces redundancy in the representation …

Android Security: Analysis And Applications, Raina Samuel

Dissertations

The Android mobile system is home to millions of apps that offer a wide range of functionalities. Users rely on Android apps in various facets of daily life, including critical, e.g., medical, settings. Generally, users trust that apps perform their stated purpose safely and accurately. However, despite the platform’s efforts to maintain a safe environment, apps routinely manage to evade scrutiny. This dissertation analyzes Android app behavior and has revealed several weakness: lapses in device authentication schemes, deceptive practices such as apps covering their traces, as well as behavioral and descriptive inaccuracies in medical apps. Examining a large corpus of …

Carrier Transport Engineering In Wide Bandgap Semiconductors For Photonic And Memory Device Applications, Ravi Teja Velpula

Dissertations

Wide bandgap (WBG) semiconductors play a crucial role in the current solid-state lighting technology. The AlGaN compound semiconductor is widely used for ultraviolet (UV) light-emitting diodes (LEDs), however, the efficiency of these LEDs is largely in a single-digit percentage range due to several factors. Until recently, AlInN alloy has been relatively unexplored, though it holds potential for light-emitters operating in the visible and UV regions. In this dissertation, the first axial AlInN core-shell nanowire UV LEDs operating in the UV-A and UV-B regions with an internal quantum efficiency (IQE) of 52% are demonstrated. Moreover, the light extraction efficiency of this …

Photonic Monitoring Of Atmospheric Fauna, Adrien P. Genoud

Dissertations

Insects play a quintessential role in the Earth’s ecosystems and their recent decline in abundance and diversity is alarming. Monitoring their population is paramount to understand the causes of their decline, as well as to guide and evaluate the efficiency of conservation policies. Monitoring populations of flying insects is generally done using physical traps, but this method requires long and expensive laboratory analysis where each insect must be identified by qualified personnel. Lack of reliable data on insect populations is now considered a significant issue in the field of entomology, often referred to as a “data crisis” in the field. …

Integrated Machine Learning And Optimization Approaches, Dogacan Yilmaz

Dissertations

This dissertation focuses on the integration of machine learning and optimization. Specifically, novel machine learning-based frameworks are proposed to help solve a broad range of well-known operations research problems to reduce the solution times. The first study presents a bidirectional Long Short-Term Memory framework to learn optimal solutions to sequential decision-making problems. Computational results show that the framework significantly reduces the solution time of benchmark capacitated lot-sizing problems without much loss in feasibility and optimality. Also, models trained using shorter planning horizons can successfully predict the optimal solution of the instances with longer planning horizons. For the hardest data set, …

Helioseismic Diagnostics Of Active Regions And Their Magnetic Fields, John T. Stefan

Dissertations

While two and a half decades of nearly constant observation by the Solar and Heliospheric Observatory (SOHO) and the Solar Dynamics Observatory (SDO) spacecraft have yielded key insights into the structure and dynamics of active regions, it is still unclear if active regions can be identified before emerging on the solar surface and, once emerged, whether the subsurface structure of an active region’s magnetic field can be measured. Regarding the dynamical processes associated with active regions, the height and mechanism of sunquake excitation remains poorly understood. To answer these questions, a comprehensive survey of active region magnetic fields and their …

Hydrodynamic Investigation Of The Discharge Of Complex Fluids From Dispensing Bottles Using Experimental And Computational Approaches, Baran Teoman

Dissertations

The discharge of non-Newtonian, complex fluids through orifices of industrial tanks, pipes, dispensers, or packaging containers is a ubiquitous but often problematic process because of the complex rheology of such fluids and the geometry of the containers. This, in turn, reduces the discharge rate and results in residual fluid left in the container, often referred to as heel. Heel formation is undesired in general, since it causes loss of valuable material, container fouling, and cross-contamination between batches. Heel may be of significant concern not only in industrial vessels but also in consumer packaging. Despite its relevance, the research in this …

Interactions Of Amyloid Peptides With Lipid Membranes, Yanxing Yang

Dissertations

The aggregation of amyloid proteins into fibrils is a hallmark of several diseases including Alzheimer’s (AD), Parkinson’s, and Type II diabetes. This aggregation process involves the formation of small size oligomers preceding the formation of insoluble fibrils. Recent studies have shown that these oligomers are more likely to be responsible for cell toxicity than fibrils. A possible mechanism of toxicity involves the interaction of oligomers with the cell membrane compromising its integrity. In particular, oligomers may form pore-like structures in the cell membrane affecting its permeability or they may induce lipid loss via a detergent-like effect. This dissertation aims to …

Machine Learning-Based Data Analytics For Understanding Space Weather And Climate, Yasser Abduallah

Dissertations

This dissertation addresses multiple crucial problems in space weather and climate, presenting new machine learning-based data analytics algorithms and models for tackling the problems.

First, the dissertation presents two new approaches to predicting solar flares. One approach, called DeepSun, predicts solar flares by utilizing a machine-learning-as-a-service (MLaaS) platform. The DeepSun system provides a friendly interface for Web users and an application programming interface (API) for remote programming users. It adopts an ensemble learning method that employs several machine learning algorithms to perform multiclass flare prediction. The other approach, named SolarFlareNet, forecasts the occurrence of solar flares within the next 24 …

Bioremediation Of Petroleum Hydrocarbons In Coastal Sediments, Charbel Abou Khalil

Dissertations

The biodegradation of dispersed crude oil in the ocean is relatively rapid (a half-life of a few weeks). However, it is often much slower on shorelines, usually attributed to low moisture content, nutrient limitation, and higher oil concentrations in beaches than in dispersed plumes. Another factor may be the increased salinity of the upper intertidal and supratidal zones since these parts of the beach are potentially subject to prolonged evaporation and only intermittent inundation. Therefore, two laboratory experiments are conducted to investigate whether such an increase in porewater salinity results in additional inhibitory effects on oil biodegradation in seashores.

In …

Combustion Soot Nanoparticles: Mechanism Of Restructuring And Mechanical Properties, Ali Hasani

Dissertations

Soot, a product of incomplete combustion of fossil fuels, is a global warming agent. The effect of soot particles on climate depends on their morphology. Freshly released soot particles are fractal lacey aggregates, but they often appear collapsed in atmospheric samples collected away from emission sources. A body of work has concluded that the collapse is caused by liquid shells when they form by vapor condensation around soot aggregates. However, some recent studies argue that soot remains fractal even when engulfed by the shells, collapsing only when the shells evaporate. To reconcile this disagreement, the effects of the condensation and …

Monitoring Climate Change With Machine Learning And Uncertainty Quantification, Firas Gerges

Dissertations

The impact of climate change on the environment has become increasingly visible today. One important topic in climate change monitoring is to forecast future climate events, which relies on long-term prediction of climate variables at a local regional scale. This topic is crucial for disaster risk management and for resolving climate change at the local level. General Circulation Models (GCMs) allow for the simulation of several climate variables, decades into the future. GCM simulations, however, are at a global large scale and are too coarse to monitor climate change at the local small scale. This dissertation explores new machine learning …

Amphiphilic Block Copolymers And The Applications In Therapeutics Delivery, Jie Dou

Dissertations

Well-defined thermo-responsive triblock copolymers containing polyethylene oxide (PEO) and poly(N-isopropyl acrylamide) PNIPAM are synthesized by a type of living controlled polymerization, named iniferter polymerization. The polymers are amphiphilic in nature and are self-assembled into a micelle. Their properties and application are characterized and investigated in this work.

Foremost, the initiator of the polymerization (iniferter) is designed and synthesized by condensation polymerization, where PEO is incorporated into the structure to improve biocompatibility, which has great potential for biological application. Moreover, this iniferter reagent could be applied to more than 70 percent of vinyl monomers.

NIPAM, a commercial vinyl monomer, is chosen …

Biotransformation And Biodefluorination Of Fluorotelomer Carboxylic Acids, Chen Wu

Dissertations

Per- and polyfluoroalkyl substances (PFASs), a class of emerging contaminants of concern, have attacked unprecedented attention given their prevalent detection and adverse health effects. Primary regulatory attention has been focused on PFOA, PFOS, and other perfluoroalkyl acids (PFAAs). Recent investigations revealed that fluorotelomer carboxylic acid (FTCAs), particularly 5:3 FTCA and 6:2 FTCA, were dominant in landfill leachates and other environmental matrixes. FTCAs are also found as common intermediates during the biotransformation of PFAA precursors. Unfortunately, FTCAs have higher bioaccumulating potential and are at least two orders more toxic than their corresponding PFCAs. However, information regarding the potentials and mechanisms of …

Polymeric Nitrogen: Computational Catalysis And Materials Design, Safa Alzaim

Dissertations

The urgent climactic crisis currently endangering all life on earth is largely due to the combustion of fossil fuels as an energy source. This work combines physics, chemistry, mathematics and computer science to develop new ways to harvest, store and use sustainable energy. In particular, this work centers on polymeric nitrogen (PN). PN is highly desirable because the energy density is extremely high. This energy density lends PN to applications such as rocket fuel and energetic materials. Recently, the polymeric phase N₈ was shown to be highly active for oxygen reduction reactions (ORR); the material is an excellent electrocatalyst …

Microplastics And Genetic Vectors Promoting The Dissemination Of Antimicrobial Resistance In Municipal Wastewater Treatment Processes, Ngoc Dung Pham

Dissertations

The spread of antimicrobial resistance in the environment and especially its transfer into human pathogens have emerged as global issues. Activated sludge units at municipal wastewater treatment plants are "hotspots" converging a multitude of contaminants, including antibiotics, antibiotic-resistant bacteria (ARB), human pathogens, and microplastics. The prevalence of antibiotics can induce stress response of sludge microbial communities and promote the development of new resistance mechanisms and transmission venues, through which the dissemination of antibiotic resistance genes (ARGs) arises as mediated by mobile genetic elements (MGEs). In this doctoral dissertation, the impacts of microplastics and genetic vectors (i.e., MGEs and bacterial hosts) …

Water Management And Corrosion Performance From Protective Polymer Coatings With Spatially Controlled Hydrophilic Domains, Jessica M. Davison

Dissertations

Metallic corrosion has become an annual multibillion-dollar problem for the industrialized world and global contamination issue through the process of repair, removing, and reapplying protective coatings. Typical corrosion resistant coatings are comprised of polymeric coating layers with anti-corrosive pigments, plasticizers, sacrificial additives, and/or other formulation materials, which are formulated to prevent, detect, and manage corrosion. Our counterintuitive approach was to improve upon the understanding of how, when, where, and why environmental contaminants (reactants, mainly water and electrolytes) driving corrosion, propagate and accumulate as localized hydrophilicity shifts within a model polymer coated substrate. Herein, hydrogel particles (HGP) were synthesized of defines …

A Framework For Assessing The 4th Rank Dispersivity Tensor Under Anisotropic Axial Symmetries, Xiang Fan

Dissertations

Multi-dimensional expansion of the advection-dispersion equation necessitated the representation of dispersivity as a 4th rank tensor. This tensorial form of dispersivity has 81 terms in three-dimensions with a maximum of 36 independent terms that may be used to describe Fickian spreading of a dissolved contaminant plume according to intrinsic properties of a porous medium. The complexity of the 4th rank tensor has led to the common practice of simplifying the tensor to only 2 or 3 independent terms by assuming isotropic conditions, although isotropic porous media are uncommon in nature as many natural geologic systems exhibit pronounced anisotropy. A broad …

Remote Sensing Application For Landslide Detection: Monitoring Along Eastern Lake Michigan (Miami Park, Mi), Guzalay Sataer

Dissertations

I assessed the nature and spatial and temporal patterns of deformation over the Miami Park bluffs on the eastern margin of Lake Michigan and investigated the factors controlling its observed deformation. Our approach involved the following steps: (1) extracting bluff deformation rates (velocities along the line of sight of the satellite) using a stack of Sentinel-1A radar imagery in ascending acquisition geometry acquired between 2017 and 2021 and applying the Intermittent Small Baseline Subset (ISBAS) InSAR time series analysis method; (2) generating high-resolution (5 cm) elevation models and orthophotos from temporal unmanned aerial vehicle (UAV) surveys acquired in 2017, 2019, …

Synthetic Amphiphiles As Antibiotic Potentiators, Helena Spikes

Dissertations

Antibiotic resistance has become a massive threat to modern medicine. Bacteria acquire resistance either through genetic mutations or mobile genetic elements, such as plasmids. The growing resistance crisis is exacerbated by over-prescription of antibiotics and improper use. As antimicrobial resistance becomes more widespread, superbugs (bacteria resistant to more than one class of drug) have evolved. Since few new drugs reach clinical trials and even fewer are approved by the FDA, we must find a way to make existing drugs more potent. One technique to accomplish this is by using combination therapy. By administering two or more drugs at a time, …

Ferrocenium Salt Aided Substitution Reactions And Synthesis Of Glycosylated Curcumin Derivatives, Deva Saroja Talasila

Dissertations

Organic synthesis has been significantly advanced with the employment of transition metal complexes. The discovery of transition metal catalysts provided the synthetic community with powerful tools for accelerating reactions and making them more selective and efficient. Many chemical reactions do not happen without a catalyst.

Iron-based catalysts have several advantages for the chemical industry because it is a non-toxic and ecologically friendly metal. Our group previously found that ferrocenium cations with a 3+ oxidation state of iron-catalyzed propargylic substitution reactions at low temperatures. The sandwich structure of ferrocenes allows substituents to be introduced on the cyclopentadienyl rings, which allows for …

Novel Thioglycosides As Versatile Glycosyl Donors For Oligosaccharide Synthesis, Ganesh Shrestha

Dissertations

This thesis is dedicated to the development of new methodologies for efficient synthesis of carbohydrate building blocks and their application to chemical glycosylation. S-Indolyl (SIn) anomeric moiety was investigated as a new leaving group. Understanding of the reaction pathways for the SIn moiety activation was achieved via the extended mechanistic study. The activation profile of indolylthio glycosides required large excess of activators. This drawback was partially addressed by the development of N-alkylated SInR derivatives. The activation process was studied by NMR and the increased understanding of the mechanism led to a discovery of different activation pathways taking place with …

Synthesis Of Novel Dna-Binding Polyamides To Prevent Cancer-Related Gene Overexpression, Huy Q. Nguyen

Dissertations

Pyrrole-imidazole polyamides (PIPs) are nanomolecular compounds designed to fit in the tight space of DNA minor grooves. As analogs of Netropsin and Distamycin A, PIPs are specifically designed to recognize the base pairs of DNA sequences. PIPs have many biological applications, such as regulating gene expression, biochemistry pathway regulations, and suppressing the development of cancer cells. SETMAR gene is the chimeric fusion of the SET domain with the mariner transposase. Its protein (Metnase) has functions involving DNA repairs in the NHEJ pathway, regulating gene expression, DNA decatenation, etc. Despite not having an active transposable element, SETMAR still has an unknown …

Software Protection And Secure Authentication For Autonomous Vehicular Cloud Computing, Muhammad Hataba

Dissertations

Artificial Intelligence (AI) is changing every technology we deal with. Autonomy has been a sought-after goal in vehicles, and now more than ever we are very close to that goal. Vehicles before were dumb mechanical devices, now they are becoming smart, computerized, and connected coined as Autonomous Vehicles (AVs). Moreover, researchers found a way to make more use of these enormous capabilities and introduced Autonomous Vehicles Cloud Computing (AVCC). In these platforms, vehicles can lend their unused resources and sensory data to join AVCC.

In this dissertation, we investigate security and privacy issues in AVCC. As background, we built our …

Cultivating Teacher Expertise In The Landscape Of Green Chemistry: The Development Of Pedagogical Content Knowledge In Beyond Benign’S Lead Teacher Program, Philip Charles Nahlik

Dissertations

Chemistry Education, Green Chemistry, Pedagogical Content Knowledge, Professional Learning Communities, Sustainability, Teacher Training

Investigation Of Carbon Dioxide Oxidation Reaction Pathways On Rh(111) Via Reflection Absorption Infrared Spectroscopy (Rairs), Elizabeth A. Jamka

Dissertations

CO oxidation, RAIRS, Rh(111), Surface Science, UHV

Evaluating The Impact Of Submarine Groundwater Discharge On Nutrients And Trace Elements In Coastal Systems: The Examples Of The Tuckean Swamp (Australia) And The Mississippi Sound (Usa), Amy Moody

Dissertations

Submarine groundwater discharge (SGD) is the advective flow of both fresh terrestrial groundwater and recirculating seawater through aquifer sediments, which is released into the coastal ocean. In this dissertation, I evaluated the impact of SGD on the distributions and input of trace metals and nutrients. In the Tuckean Swamp, an estuary in Australia dominated by coastal acid sulfate soils, I determined the impact of groundwater on Ba and U during the flood season, when the local aquifer is flushed out after a rapid increase in water table elevation. For Ba and U, groundwater contributed up to 18 and 66 % …

Analyzing Fluctuation Of Topics And Public Sentiment Through Social Media Data, Haoyue Liu

Dissertations

Over the past decade years, Internet users were expending rapidly in the world. They form various online social networks through such Internet platforms as Twitter, Facebook and Instagram. These platforms provide a fast way that helps their users receive and disseminate information and express personal opinions in virtual space. When dealing with massive and chaotic social media data, how to accurately determine what events or concepts users are discussing is an interesting and important problem.

This dissertation work mainly consists of two parts. First, this research pays attention to mining the hidden topics and user interest trend by analyzing real-world …

Computation Of Risk Measures In Finance And Parallel Real-Time Scheduling, Yajuan Li

Dissertations

Many application areas employ various risk measures, such as a quantile, to assess risks. For example, in finance, risk managers employ a quantile to help determine appropriate levels of capital needed to be able to absorb (with high probability) large unexpected losses in credit portfolios comprising loans, bonds, and other financial instruments subject to default. This dissertation discusses the computation of risk measures in finance and parallel real-time scheduling.

Firstly, two estimation approaches are compared for one risk measure, a quantile, via randomized quasi-Monte Carlo (RQMC) in an asymptotic setting where the number of randomizations for RQMC grows large, but …

Stochastic Modeling Of Flows In Membrane Pore Networks, Binan Gu

Dissertations

Membrane filters provide immediate solutions to many urgent problems such as water purification, and effective remedies to pressing environmental concerns such as waste and air treatment. The ubiquity of applications gives rise to a significant amount of research in membrane material selection and structural design to optimize filter efficiency. As physical experiments tend to be costly, numerical simulation and analysis of fluid flow, foulant transport and geometric evolution due to foulant deposition in complex geometries become particularly relevant. In this dissertation, several mathematical modeling and analytical aspects of the industrial membrane filtration process are investigated. A first-principles mathematical model for …