Physical Sciences and Mathematics Commons^™

Hpc Enabled Data Analytics For High-Throughput High-Content Cellular Analysis, Ross A. Smith, Rhonda J. Vickery, Jack Harris, Sara Gharabaghi, Thomas Wischgoll, David Short, Robert Trevino, Steven A. Kawamoto, Thomas J. Lamkin, Kevin Schoen, Eric E. Bardes, Scott C. Tabar, Bruce J. Aronow

Computer Science and Engineering Faculty Publications

Biologists doing high-throughput high-content cellular analysis are generally not computer scientists or high performance computing (HPC) experts, and they want their workflow to support their science without having to be. We describe a new HPC enabled data analytics workflow with a web interface, HPC pipeline for analysis, and both traditional and new analytics tools to help them transition from a single workstation mode of operation to power HPC users. This allows the processing of multiple plates over a short period of time to ensure timely query and analysis to match potential countermeasures to individual responses.

Nitrogen Removal And Recycling By Sediments In The Lower Great Miami River, Ohio, Lee A. Slone

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The Lower Great Miami River (LGMR) has recently experienced algal blooms due to excess nitrogen (N) and phosphorus (P). Some Ohio water treatment plants were ordered to reduce the amount of P that they release into the river, but N also can stimulate eutrophication and algal blooms, either alone or in combination with P. In this study, LGMR sediment N transformations and effects of river impoundments on N cycling were compared with external N loads during different flow conditions to determine the extent to which N is removed or recycled within the system. Sediment nutrient fluxes, sediment N sinks and …

Distributed Rule-Based Ontology Reasoning, Raghava Mutharaju

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The vision of the Semantic Web is to provide structure and meaning to the data on the Web. Knowledge representation and reasoning play a crucial role in accomplishing this vision. OWL (Web Ontology Language), a W3C standard, is used for representing knowledge. Reasoning over the ontologies is used to derive logical consequences. A fixed set of rules are run on an ontology iteratively until no new logical consequences can be derived. All existing reasoners run on a single machine, possibly using multiple cores. Ontologies (sometimes loosely referred to as knowledge bases) that are automatically constructed can be very large. Single …

Customizable 3-D Virtual Gi Tract Systems For Locating, Mapping, And Navigation Inside Human Gastrointestinal Tract, Megha Dattatrey Dalvi

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One of the critical challenges of wireless capsule endoscopy examination is to find the exact position of the capsule in the Gastrointestinal Tract (GI) tract so as to correctly and accurately spot the position of the intestinal diseases. Creating a 3D virtual GI tract system could significantly improve the capsule endoscopy operations. The virtual human model, such as the BioDigital Human, has been credited as Google Earth for the human body, which provides us medically accurate virtual body and organ structures. However, it only assembles a “Standard” human body. The problem is: there is only one earth, but billions of …

Thermal Properties Of Poly(Arylene Ether)S Prepared From N,N-Dialkyl-2,4-Difluorobenzenesulfonamides, James Kanyoko Waweru

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A series of poly(arylene ether)s were synthesized by nucleophilic aromatic substitution reaction (NAS) polycondensation of N,N-dialkyl-2,4-difluorobenzenesulfonamides. The aim of the project was to determine the thermal properties of poly(arylene ether)s by varying pendent sulfonamide activating group. The sulfonamide-activated monomers were synthesized by reacting 2,4-difluorobenzenesulfonyl chloride with a series of n-alkyl, iso-alkyl and cycloalkyl amines, ranging from n-propyl to n-octyl. Their poly(arylene ether)s were prepared with bisphenol-A as the nucleophilic reaction partner. The 4’-bromo-2,4-difluorodiphenylsulfone monomer, was utilized to synthesized copolymer with 4,4’-difluorodiphenylsulfone and bisphenol-A. The polymers were characterized by 1H and 13C NMR spectroscopy, TGA, DSC and SEC. Sulfonamide based polymers, …

Augment Hololens’ Body Recognition And Tracking Capabilities Using Kinect, Krishna Chaithanya Mathi

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In this thesis, we are primarily interested in exploring the HoloLens technologies for medical practices. Particularly, we will address the limitation of HoloLens’ capability in human body sensing, recognition and tracking. We will then introduce and demonstrate the use of Kinect to augment HoloLens’ sensory and processing capabilities in order to produce time and space-synchronized immersive environment with both virtual body and real body of the same patient for supporting distributed medical collaborations. Specifically, we are looking at a distributed solution in which we are collecting the patient body data from Kinect, followed by body recognition and position/motion tracking processing …

Novel Cost And Space Efficient Range Of Motion And Gait Analysis Systems, Rutvik Bharatkumar Patel

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In this thesis, we have explored the use of the latest motion tracking technologies, as evident by Microsoft Xbox Kinect’s motion tracking capabilities, in combination with 3D digital human modeling and animation, multi-modality image capturing and processing, and fusion, to design a new generation of low-cost range of motion and gait analysis solutions that overcome the limitation of existing tools. The proposed solutions and our prototype systems have demonstrated accurate measurements and reliable analysis outcome compared to current clinic practices, with significantly reduced complexity and cost. Furthermore, it eliminates the need for expensive effort for pre- and post- processing of …

Development Of Analytical Equations For Optimum Tilt Of Two-Axis And Single-Axis Rotating Solar Panels For Clear-Atmosphere Condition, Gaurav Subhash Gugale

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Solar Energy is a renewable energy source which is used widely in recent times. Photovoltaic panels collect the sun’s energy and convert it to electricity. Photovoltaic panels are being widely used in both domestic applications, commercial applications, and small-scale power generation applications. Photovoltaic panels are easy to install, they generate most of their power when electrical demands peak, prices of photovoltaic panels are dropping rapidly, photovoltaic panels require low maintenance, their operating costs are minimal, and they are highly suitable for remote applications. The amount of electricity produced by photovoltaic panels depends on the amount of sunlight the panel captures. …

Synthesis, Characterization, And Polymerization Of Sulfonamide Based Bifunctional Monomers, Brady Hall

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A series of bifunctional monomers based on N,N-diallylbenzenesulfonamides with varying groups on the benzene moiety were investigated. The main goal of this project was to polymerize these monomers using radical and acyclic diene metathesis (ADMET) polymerization methods to polymerize through the allyl groups, and nucleophilic aromatic substitution (SNAr) to polymerize through the fluorine groups on the phenyl ring. Using phenyl substituted benzenesulfonyl chloride derivatives as a starting material, a series of N,N-diallylbenzenesulfonamide derivatives were prepared. The ADMET and radical cyclopolymerizations were monitored by 1H NMR spectroscopy, observing the disappearance of signals for the allyl groups in both, and the appearance …

A Study Of Social Web Data On Buprenorphine Abuse Using Semantic Web Technology, Raminta Daniulaityte, Amit P. Sheth

Kno.e.sis Publications

The Specific Aims of this application are to use a paradigmatic approach that combines Semantic Web technology, Natural Language Processing and Machine Learning techniques to:

1) Describe drug users’ knowledge, attitudes, and behaviors related to the non-medical use of Suboxone and Subutex as discussed on Web-based forums.
2) Identify and describe temporal patterns of non-medical use of Suboxone and Subutex as discussed on Web-based forums.

The research was carried out by an interdisciplinary team of members of the Center for Interventions, Treatment and Addictions Research (CITAR) and the Ohio Center of Excellence in Knowledge- enabled Computing (Kno.e.sis) at Wright State …

Building The Web Of Knowledge With Smart Iot Applications, Amelie Gyrard, Pankesh Patel, Amit P. Sheth, Martin Serrano

Kno.e.sis Publications

The Internet of Things (IoT) is experiencing fast adoption because of its positive impact to change all aspects of our lives, from agriculture in rural areas, to health and wellness, to smart home and smart-x applications in cities. The development of IoT applications and deployment of smart IoT-based solutions is just starting; smart IoT applications will modify our physical world and our interaction with cyber spaces, from how we remotely control appliances at home to how we care for patients or elderly persons. The massive deployment of IoT devices represents a tremendous economic impact and at the same time offers …

Co-Evolution Of Rdf Datasets, Sidra Faisal, Kemele M. Endris, Saeedeh Shekarpour, Sören Auer, Maria-Esther Vidal

Kno.e.sis Publications

Linking Data initiatives have fostered the publication of large number of RDF datasets in the Linked Open Data (LOD) cloud, as well as the development of query processing infrastructures to access these data in a federated fashion. However, different experimental studies have shown that availability of LOD datasets cannot be always ensured, being RDF data replication required for envisioning reliable federated query frameworks. Albeit enhancing data availability, RDF data replication requires synchronization and conflict resolution when replicas and source datasets are allowed to change data over time, i.e., co-evolution management needs to be provided to ensure consistency. In this paper, …

An Autoencoder-Based Image Descriptor For Image Matching And Retrieval, Chenyang Zhao

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Local image features are used in many computer vision applications. Many point detectors and descriptors have been proposed in recent years; however, creation of effective descriptors is still a topic of research. The Scale Invariant Feature Transform (SIFT) developed by David Lowe is widely used in image matching and image retrieval. SIFT detects interest points in an image based on Scale-Space analysis, which is invariant to change in image scale. A SIFT descriptor contains gradient information about an image patch centered at a point of interest. SIFT is found to provide a high matching rate, is robust to image transformations; …

Synthesis And Characterization Of Functionalized Poly(Arylene Ether Sulfone)S Using Click Chemistry, Kavitha Neithikunta

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Poly(arylene ether sulfone)s with pendent aryl iodide group was successfully synthesized via Nucleophilic aromatic polycondensation of 1-(3,5-difluorophenyl sulfonyl)-4-iodobenzene using 4,4’-difluorodiphenylsulfone (DFDPS) and Bisphenol A in the ratio 25:75:100. Iodo monomer was prepared by reacting 3,5-difluorodiphenyl sulfone with N-iodo succinimide (NIS). Using GC/MS and NMR spectroscopy, the quantitative analysis was done to this monomer. Modification was done to iodo copolymer using sodium azide and copper sulfate as catalyst to form azide copolymer. Further modification of the azide copolymer to triazole copolymers via Click Chemistry using different alkynes such as 1-octyne, phenyl acetylene, propargyl alcohol and acetylenedicarboxylic acid. Polymers characterization was done …

Thermoelectric Transport And Energy Conversion Using Novel 2d Materials, Luke J. Wirth

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Nanomaterials hold great promise for applications in thermal management and thermoelectric power generation. Defects in these are important as they are generally inevitably introduced during fabrication or intentionally engineered to control the properties of the nanomaterials. Here, we investigate how phonon-contributed thermal conductance in narrow graphene, boron nitride (BN), and silicene nanoribbons (NRs), responds to the presence of a vacancy defect and the corresponding geometric distortion, from first principles using the non-equilibrium Green's function method. Analyses are made of the geometries, phonon conductance coefficients, and local densities of states (LDOS) of pristine and defected nanoribbons. It is found that hydrogen …

Intelligent Caching To Mitigate The Impact Of Web Robots On Web Servers, Howard Nathan Rude

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With an ever increasing amount of data that is shared and posted on the Web, the desire and necessity to automatically glean this information has led to an increase in the sophistication and volume of software agents called web robots or crawlers. Recent measurements, including our own across the entire logs of Wright State University Web servers over the past two years, suggest that at least 60\% of all requests originate from robots rather than humans. Web robots display different statistical and behavioral patterns in their traffic compared to humans, yet present Web server optimizations presume that traffic exhibits predominantly …

De-Anonymization Attack Anatomy And Analysis Of Ohio Nursing Workforce Data Anonymization, Jacob M. Miracle

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Data generalization (anonymization) is a widely misunderstood technique for preserving individual privacy in non-interactive data publishing. Easily avoidable anonymization failures are still occurring 14 years after the discovery of basic techniques to protect against them. Identities of individuals in anonymized datasets are at risk of being disclosed by cyber attackers who exploit these failures. To demonstrate the importance of proper data anonymization we present three perspectives on data anonymization. First, we examine several de-anonymization attacks to formalize the anatomy used to conduct attacks on anonymous data. Second, we examine the vulnerabilities of an anonymous nursing workforce survey to convey how …

Identifying Offensive Videos On Youtube, Rajeshwari Kandakatla

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Harassment on social media has become a critical problem and social media content depicting harassment is becoming common place. Video-sharing websites such as YouTube contain content that may be offensive to certain community, insulting to certain religion, race etc., or make fun of disabilities. These videos can also provoke and promote altercations leading to online harassment of individuals and groups. In this thesis, we present a system that identifies offensive videos on YouTube. Our goal is to determine features that can be used to detect offensive videos efficiently and reliably. We conducted experiments using content and metadata available for each …

Computer Graphics And Visualization Based Analysis And Record System For Hand Surgery And Therapy Practice, Venkatamanikanta Subrahmanyakartheek Gokavarapu

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In this thesis, we have designed and developed a computer graphics and visualization based analysis and record system for hand surgery and therapy practice. In particular, we have designed and developed three novel technologies: (i) model-based data compression for hand motion records (ii) model-based surface area estimation of a human hand and (iii) an emulated study of hand wound area estimation. First, we have presented a new data compression technique to better address the needs of electronic health record systems, such as file storage and privacy. In our proposed approach, we will extract the patient's hand motion information and store …

Symmetric Colorings Of The Hypercube And Hyperoctahedron, Bo Phillips

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A self-complementary graph G is a subgraph of the complete graph K_n that is isomorphic to its complement. A self-complementary graph can be thought of as an edge 2-coloring of K_n that admits a color-switching automorphism. An automorphism of K_n that is color-switching for some edge 2-coloring is called a complementing automorphism. Complementing automorphisms for K_n have been characterized in the past by such authors as Sachs and Ringel. We are interested in extending this notion of self-complementary to other highly symmetric families of graphs; namely, the hypercube Q_n and its dual graph, the hyperoctahedron O_n. To that end, …

A Stochastic Petri Net Based Nlu Scheme For Technical Documents Understanding, Adamantia Psarologou

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Natural Language Understanding (NLU) is a very old research field, which deals with machine reading comprehension. Despite the many years of work and the numerous accomplishments by several researchers in the field, there is still place for significant improvements. Here, our goal is to develop a novel NLU methodology for detecting and extracting event/action associations in technical documents. In order to achieve this goal we present a synergy of methods (Kernel extraction, Formal Language Modeling, Stochastic Petri-nets (SPN) mapping and Event Representation via SPN graph synthesis). In particular, the basic meaning of a natural language sentence is given by its …

An Investigation Of The Adsorption Behavior Between Silver Nanoparticles (Agnps) And Corundum (Α-Al2O3) At Environmental Ph Values Using Inductively-Coupled Plasma Optical Emission Spectroscopy (Icp-Oes) And Raman Spectroscopy, Kevin Andrew O'Neil

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With the increased use of silver nanoparticles (AgNPs) in consumer products, the need to monitor their release into environmental soils has become critical. Although minerals make up a large component of soils, research on their interactions with AgNPs is still limited. Furthermore, the majority of the existing research focused on silica-based minerals rather than metal oxides, which is the second most abundant mineral type in the earth's crust. This study examined for the first time the aqueous interaction between the widely used, spherical Creighton AgNPs and a-corundum (a-Al2O3), a representative non-silica-based mineral, at environmentally relevant pH values (6-11). Samples were …

Mining And Analyzing Subjective Experiences In User Generated Content, Lu Chen

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Web 2.0 and social media enable people to create, share and discover information instantly anywhere, anytime. A great amount of this information is subjective information -- the information about people's subjective experiences, ranging from feelings of what is happening in our daily lives to opinions on a wide variety of topics. Subjective information is useful to individuals, businesses, and government agencies to support decision making in areas such as product purchase, marketing strategy, and policy making. However, much useful subjective information is buried in ever-growing user generated data on social media platforms, it is still difficult to extract high quality …

Application Of Geographical Information Systems To Determine Human Population Impact On Water Resources Of Yellow Springs, Ohio, And The Use Of Lidar Intensities In Land Use Classification, Gregory Geise

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The purposes of the following studies were to investigate natural and human influences on several spatial and temporal aspects of a local and regional environment. The decreasing discharge rate of the ground water supplied Yellow Spring may be caused by the increase in population of the nearby Village of Yellow Springs, Ohio. Periodic measurements of Yellow Spring's discharge rate compared to changes in the town's population showed an inverse relationship, where spring discharge declined as population grew. A sharp decrease in discharge occurred during a period when the spring's facade was modified and an airport was built partially overlying the …

A Social Network Analysis Of An Introductory Calculus-Based Physics Class With Comparisons Of Traditional And Non-Traditional Students, Fci Scores, And Network Centralities, Emily Sandt

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The use of social network analysis in physics education research seeks to advance understanding of how students' collaborative tendencies influence trends of learning. Common useful measurements are network size, density of connections, and centrality measures that describe the importance of nodes' positions. This study compared four different centrality measures at the beginning and end of seven sections of an introductory calculus-based physics course. The Force Concept Inventory was used as a measure of conceptual learning at pre- and post-course administrations. The main focus of this study was to identify if differences in network centralities and conceptual learning/knowledge exist with respect …

Theoretical Estimation Of PkA'S Of Pyrimidines And Related Heterocycles, Rachael Ann Wessner

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Pyrimidines and related heterocycles are an important class of compounds with a wide variety of applications. As a result, there is great interest in the chemical properties of these compounds, specifically their pKa's. Despite the importance of these compounds their reported pKa's are often only approximations or are completely absent from literature. Experimentally measuring pKa's can be challenging, especially if the pKa is below zero. Alternatively, pKa's can be estimated computationally using a Quantitative Structure-Activity Relationship (QSAR). However, most of the compounds included in this study exist as two or more forms that arise from tautomerism. Tautomerism complicates the estimation …

Computer Modeling Of A Solar Thermal System For Space Heating, Dhananjay D. Deshpande

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Most applications of flat plate, low-temperature solar thermal panels are for water heating, such as producing domestic hot water or raising the temperature of swimming pools. This is reasonable given that the large masses of water present in these systems inherently provide built-in thermal energy storage so that a separate energy storage tank does not have to be purchased. For a space heating system, extra thermal energy storage generally has to be purchased and is a detriment to the economics of these systems. Despite the economic drawbacks of solar thermal space heating, this thesis focuses on the size of thermal …

Design And Application Of Facile Routes To N-Heterocycle Functionalized Poly(Arylene Ether)S, Abraham K. Kemboi

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A series of 3,5-difluorinated systems, which are activated towards nucleophilic aromatic substitution (NAS) by the strongly electron withdrawing benzoxazole or benzothiazole groups, located meta to the fluorines were prepared and fully characterized. The monomers also carry various N-heterocyclic species on the non-fluorinated ring. The corresponding poly(arylene ether)s, some of which were copolymers with triphenylphosphine oxide-based monomers, were prepared via standard NAS polycondensation reactions. Incorporation of the monomers containing N-heterocycle units was determined by NMR spectroscopy. Characterization of the thermal properties was done using thermogravimetric analysis (TGA) and differential scanning (DSC). Most of the polymers displayed good film forming properties when …

Convergent Evolution In Tooth Morphology Of Filter Feeding Lamniform Sharks, Michaela Grace Mitchell

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The basking shark (Cetorhinus maximus) and megamouth shark (Megachasma pelagios) are two species of filter feeding sharks, both belonging to the order Lamniformes. There are two conflicting hypotheses regarding the origins of filter feeding in Lamniform sharks; that there is a single origin of filter feeding within Lamniformes, or conversely, the filter feeding adaptations have been developed independently due to different ancestral conditions. Evidence obtained from several studies strongly supports the latter hypothesis. Because evidence suggests that C. maximus and M. pelagios have developed their filter feeding adaptations independently, we expect to see convergent evolution taking place within these two …

Measures Of User Interactions, Conversations, And Attacks In A Crowdsourced Platform Offering Emotional Support., Samir Yelne

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Online social systems have emerged as a popular medium for people in society to communicate with each other. Among the most important reasons why people communicate is to share emotional problems, but most online social systems are uncomfortable or unsafe spaces for this purpose. This has led to the rise of online emotional support systems, where users needing to speak to someone can anonymously connect to a crowd of trained listeners for a one-on-one conversation. To better understand who, how and when users utilize these systems, and to evaluate their safety, this thesis offers a comprehensive examination of the characteristics …