Physical Sciences and Mathematics Commons^™

Towards A Pattern-Based Ontology For Chemical Laboratory Procedures, Cogan Shimizu, Leah Mcewen, Quinn Hirt

Computer Science and Engineering Faculty Publications

There is an increasing expectation in the academic sector for chemistry researchers to conduct risk assessment during experimental planning. However, information concerning laboratory scale chemical reactivity hazards can be difficult to parse despite ongoing efforts to compile from reported incidents. Laboratory procedures do not always directly flag possible incompatibilities among constituents or other process factors. In this paper, we present a pattern-based ontology for capturing multiple factors involved in laboratory procedures, including chemical properties, states, conditions, actions, and associated hazard classifications.

Metrics For Evaluating Quality Of Embeddings For Ontological Concepts, Faisal Alshargi, Saeedeh Shekarpour, Tommaso Soru, Amit P. Sheth

Kno.e.sis Publications

Although there is an emerging trend towards generating embeddings for primarily unstructured data and, recently, for structured data, no systematic suite for measuring the quality of embeddings has been proposed yet. This deficiency is further sensed with respect to embeddings generated for structured data because there are no concrete evaluation metrics measuring the quality of the encoded structure as well as semantic patterns in the embedding space. In this paper, we introduce a framework containing three distinct tasks concerned with the individual aspects of ontological concepts: (i) the categorization aspect, (ii) the hierarchical aspect, and (iii) the relational aspect. Then, …

Lead In Tap Water From The City Of Dayton, Ohio, Kayla Marie Haman

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Lead (Pb) in public tap water is a national health concern and is the main pathway of human exposure to Pb. The City of Dayton has verified Pb pipelines and homes with Pb plumbing; thus, residents are at risk to Pb leaching into their tap water. I sampled water from 130 residential and 24 public water taps and measured Pb and copper (Cu). Five percent of samples exceeded the action level for Pb (> 15 [micro]g/L) and none exceeded the action level for Cu. The City of Dayton's lead pipeline map identifies potential Pb exposure from Pb distribution pipes. However, …

A Lc-Ms/Ms-Based Method For The Multiplex Detection Of 24 Fentanyl Analogs And Metabolites In Whole Blood At Sub Ng Ml-1 Concentrations, Kraig Edward Strayer

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The United States and numerous other countries worldwide are currently experiencing a public health crisis due to the abuse of illicitly manufactured fentanyl (IMF) and its analogues. This manuscript describes the development of a liquid chromatography-tandem mass spectrometry-based method for the multiplex detection of N = 24 IMF analogues and metabolites in whole blood at concentrations as low as 0.1-0.5 ng mL-1. These available IMFs were fentanyl, norfentanyl, furanyl norfentanyl, remifentanil acid, butyryl norfentanyl, remifentanil, acetyl fentanyl, alfentanil, AH-7921, U-47700, acetyl fentanyl 4-methylphenethyl, acrylfentanyl, para-methoxyfentanyl, despropionyl fentanyl (4-ANPP), furanyl fentanyl, despropionyl para-fluorofentanyl, carfentanil, (±)-cis-3-methyl fentanyl, butyryl fentanyl, isobutyryl fentanyl, sufentanil, …

Gender Fairness Within The Force Concept Inventory, Adrienne L. Traxler, Rachel Henderson, John Stewart, Gay Stewart, Alexis Papak, Rebecca Lindell

Physics Faculty Publications

Research on the test structure of the Force Concept Inventory (FCI) has largely ignored gender, and research on FCI gender effects (often reported as “gender gaps”) has seldom interrogated the structure of the test. These rarely crossed streams of research leave open the possibility that the FCI may not be structurally valid across genders, particularly since many reported results come from calculus-based courses where 75% or more of the students are men. We examine the FCI considering both psychometrics and gender disaggregation (while acknowledging this as a binary simplification), and find several problematic questions whose removal decreases the apparent gender …

Caregiver Assessment Using Smart Gaming Technology: A Preliminary Approach, Garrett Goodman, Tanvi Banerjee, William Romine, Cogan Shimizu, Jennifer Hughes

Computer Science and Engineering Faculty Publications

As pre-diagnostic technologies are becoming increasingly accessible, using them to improve the quality of care available to dementia patients and their caregivers is of increasing interest. Specifically, we aim to develop a tool for non- invasively assessing task performance in a simple gaming application. To address this, we have developed Caregiver Assessment using Smart Technology (CAST), a mobile application that personalizes a traditional word scramble game. Its core functionality uses a Fuzzy Inference System (FIS) optimized via a Genetic Algorithm (GA) to provide customized performance measures for each user of the system. With CAST, we match the relative level of …

Structure-Property Relationships In Paes Prepared From 2-(2,4-Difluorophenyl)Benzoxazole Derivatives, Amy Slaybaugh

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The synthesis of N-heterocycle functionalized poly(arylene ether)s, derived from 2-(2,4-difluorophenyl)benzoxazole, was explored. The platform monomer, 2-(2,4-difluorophenyl)benzoxazole (3), was prepared in one-step and characterized using NMR spectroscopy and elemental analysis. The “pre” approach involved introducing a carbazole moiety, using a copper catalyzed C-N coupling reaction, while the “post” approach required conversion of monomer 3 to the corresponding poly(arylene ether)s (PAE)s first, then performing the C-N coupling reaction. Both “pre” and “post” approaches utilized bisphenol-A (BPA) and 4,4’-difluorophenylsulfone (DPS) as comonomers as well as 4,4’-dihydroxydiphenyl ether (DPE) and 4,4’difluorotriphenylphosphine oxide (dfTPPO). All of the materials had sufficient molecular weights (Mn) to allow …

The Great Potential Of Redox Active Ligands: Applications In Cancer Research And Redox Active Catalysis, Meredith Miles

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Metal N-heterocyclic carbene (NHC) complexes have recently gained much popularity due to their tunable, steric, and electronic properties. Applications for such versatile molecules include organocatalysis, olefin metathesis, sundry cyclization reactions, and materials chemistry. Redox active NHCs are of special interest due to their ability to alter the electronic properties of the metal centers they are ligated to. In the first chapter, Au(I)-NHC complexes were synthesized and tested for biological activity in human cancer cell lines. Increasing reactive oxygen species (ROS) in cellular systems has proven to be a successful pathway for treating cancer. The redox active group in this case …

Experimental Validation Of The Generalized Harvey-Shack Surface Scatter Theory, Kevin T. Nattinger

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The Generalized Harvey-Shack (GHS) surface scatter theory claims to predict the scatter from rough surfaces over a wide domain of validity but has not been widely implemented or tested. The focus of this research is to provide a documented implementation and experimental validation of the GHS theory for the prediction of the bidirectional reflectance distribution function (BRDF) from real rough surfaces. First, the GHS theory was developed for the MATLAB software and the details of its implementation and application to experimental comparison are discussed. Next, a BRDF measurement system was designed, built, and validated. The BRDF of the Spectralon reflectance …

Synthesis Of 5-Methyl-3-Phenyl-1,3,4-Oxadiazol-2(3h)-One Derivatives By Electrophilic Aromatic Substitution, Amanda Solis Conde

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An important research element in the Turnbull laboratory has been the one-pot synthesis of 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one from sydnone. The present study reexamined the reaction of 5-methyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one with electrophiles and optimized methods for synthesis of oxadiazolinone derivatives. Further the oxadiazolinone derivatives were reacted with electrophiles to better comprehend the donating ability of the oxadiazolinone ring system in general with the expectation that the oxadiazolinone ring system is a slightly donating system. Additionally, when the structure assignment of the oxadiazolinone derivative was ambiguous, the corresponding oxadiazolinone or it’s isomer was synthesized from the appropriate sydnone to validate or refute the suggested structure. The …

"What's Ur Type?" Contextualized Classification Of User Types In Marijuana-Related Communications Using Compositional Multiview Embedding, Ugur Kursuncu, Manas Gaur, Usha Lokala, Anurag Illendula, Krishnaprasad Thirunarayan, Raminta Daniulaityte, Amit P. Sheth, Budak Arpinar

Kno.e.sis Publications

With 93% of pro-marijuana population in US favoring legalization of medical marijuana, high expectations of a greater return for Marijuana stocks, and public actively sharing information about medical, recreational and business aspects related to marijuana, it is no surprise that marijuana culture is thriving on Twitter. After the legalization of marijuana for recreational and medical purposes in 29 states, there has been a dramatic increase in the volume of drug-related communication on Twitter. Specifically, Twitter accounts have been established for promotional and informational purposes, some prominent among them being American Ganja, Medical Marijuana Exchange, and Cannabis Now. Identification and characterization …

Personalized Prediction Of Suicide Risk For Web-Based Intervention, Amanuel Alambo, Manas Gaur, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jeremiah Schumm, Jyotishman Pathak, Amit P. Sheth

Kno.e.sis Publications

Across the United States, suicide is the second leading cause of death for people aged between 15 and 34, and younger people are more prone to mental health problems, suicidal thoughts, and behaviors. For instance, 80% of patients with Borderline Personality Disorder have suicide-related behaviors, and between 4-9% of them commit suicide. Moreover, the social stigma associated with mental health issues and suicide deter patients from sharing their experiences directly with others. In such a situation, social media that provides a free and open forum for voluntary expression can provide insights into suicide ideation and self-destructive behavior.

Reddit is a …

Feasibility Of Recording Sleep Quality And Sleep Duration Using Fitbit In Children With Asthma, Amit Sheth, Hong Y. Yip, Utkarshani Jaimini, Dipesh Kadariya, Vaikunth Sridharan, Revathy Venkataramanan, Tanvi Banerjee, Krishnaprasad Thirunarayan, Maninder Kalra

Kno.e.sis Publications

Sleep disorders are common in children with asthma and are increasingly implicated in poor asthma control. Smart wearables such as the Fitbit wristband allow monitoring of users’ sleep duration and quality in their natural surroundings. However, the utility and efficacy of using such wearable devices to monitor sleep in pediatric patients with asthma have not been well-established. Thus, the objective of this study is to demonstrate the feasibility of recording sleep quality and sleep duration using Fitbit in children with asthma.

Khealth Digital Personalized Healthcare Technology For Pediatric Asthma, Utkarshani Jaimini, Hong Y. Yip, Revathy Venkataramanan, Dipesh Kadariya, Vaikunth Sridharan, Tanvi Banerjee, Krishnaprasad Thirunarayan, Maninder Kalra, Amit Sheth

Kno.e.sis Publications

Episodic:Traditional Clinician Centric Healthcare

Questions to be answered:

1.Can we reduce the number of asthma attacks through continuous monitoring of the patient's health condition?

2.Can we predict the asthma attack based on the data collected from the patient?

3.Can we predict the asthma vulnerability score for a patient?

4.Can we predict the asthma severity level of a patient?

5.Can we understand the casual relationship between the asthma symptom and the possible factors responsible for it?

Personalized Health Knowledge Graph, Amelia Gyrard, Manas Gaur, Saeedeh Shekarpour, Krishnaprasad Thirunarayan, Amit Sheth

Kno.e.sis Publications

Our current health applications do not adequately take into account contextual and personalized knowledge about patients. In order to design “Personalized Coach for Healthcare” applications to manage chronic diseases, there is a need to create a Personalized Healthcare Knowledge Graph (PHKG) that takes into consideration a patient’s health condition (personalized knowledge) and enriches that with contextualized knowledge from environmental sensors and Web of Data (e.g., symptoms and treatments for diseases). To develop PHKG, aggregating knowledge from various heterogeneous sources such as the Internet of Things (IoT) devices, clinical notes, and Electronic Medical Records (EMRs) is necessary. In this paper, we …

Investigating Problems With Mathematical Proof Skills, Samantha Collier

The University Honors Program

This research paper is focused on identifying and exploring problems that high school students have with the mathematical proof process. The study described in this report was designed to answer the question, do students who tend to struggle with mathematical proofs also struggle with understanding what is known and unknown in a proof, making assumptions about figures, and understanding mathematical converses? To answer these questions, students at three Dayton area high schools completed tasks relating to proofs and converse statements as well as a questionnaire. Contrary to the initial hypothesis, students who were perceived to have greater proof abilities did …

A Stochastic Petri Net Reverse Engineering Methodology For Deep Understanding Of Technical Documents, Giorgia Rematska

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Systems Reverse Engineering has gained great attention over time and is associated with numerous different research areas. The importance of this research derives from several technological necessities. Security analysis and learning purposes are two of them and can greatly benefit from reverse engineering. More specifically, reverse engineering of technical documents for deeper automatic understanding is a research area where reverse engineering can contribute a lot. In this PhD dissertation we develop a novel reverse engineering methodology for deep understanding of architectural description of digital hardware systems that appear in technical documents. Initially, we offer a survey on reverse engineering of …

Interpretation Of A Seismic Reflection Survey And Geophysical Well Logs In Jay County, Indiana: Orientation And Composition Of A Carbonate Layer Below The Mount Simon Sandstone, Md Saiful Alam

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In August 2017, a dynamite-sourced 2D seismic reflection survey was conducted along a gravel road northwest of Portland, Indiana. The main focus of the survey was to determine the orientation of a lithologic unit previously identified by Welder (2014) on a similar 2D seismic reflection survey in the same area. Drillers logs of two wells within this area identified a limestone layer below the Mt. Simon Sandstone, and a similar limestone layer was identified in a well drilled in Clark County, Ohio. As the focus of this study, this limestone layer will be informally named the `Votaw limestone'. The seismic …

Building An Abstract-Syntax-Tree-Oriented Symbolic Execution Engine For Php Programs, Jin Huang

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This thesis presents the design, implementation, and evaluation of an abstract-syntax-tree-oriented symbolic execution engine for the PHP programming language. As a symbolic execution engine, our system emulate the execution of a PHP program by assuming that all inputs are with symbolic rather than concrete values. While our system inherits the basic definition of symbolic execution, it fundamentally differs from existing symbolic execution implementations that mainly leverage intermediate representation (IRs) to operate. Specifically, our system directly takes the abstract syntax tree (AST) of a program as input and subsequently interprets this AST. Performing symbolic execution using AST offers unique advantages. First, …

Slim Embedding Layers For Recurrent Neural Language Models, Zhongliang Li

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Recurrent neural language (RNN) models are the state-of-the-art method for language modeling. When the vocabulary size is large, the space taken to store the model parameters becomes the bottleneck for the use of these type of models. We introduce a simple space compression method that stochastically shares the structured parameters at both the input and output embedding layers of RNN models to significantly reduce the size of model parameters, but still compactly represents the original input and the output embedding layers. The method is easy to implement and tune. Experiments on several data sets show that the new method achieves …

An Autonomous Intelligent Robotic Wheelchair To Assist People In Need: Standing-Up, Turning-Around And Sitting-Down, Iosif Papadakis Ktistakis

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The world’s ageing population has significantly increased over the last decades, which will result in one of the most significant transformations of the twenty-first century. As people age, they become more vulnerable to diseases and their health may need constant monitoring. At the same time, the number of people who have some kind of disability is also increasing. These people with disabilities may need daily assistance and monitoring of their health condition that is provided by specialists (health providers) at a high cost. A possible solution to the aforementioned problem comes from the assistive and intelligent robotics research area. The …

Interactive Visualization Of Search Results Of Large Document Sets, James D. Anderson

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When presented with many search results, finding information or patterns within the data poses a challenge. This thesis presents the design, implementation and evaluation of a visualization enabling users to browse through voluminous information and comprehend the data. Implemented with the JavaScript library Data Driven Documents (D3), the visualization represents the search as clusters of similar documents grouped into bubbles with the contents depicted as word-clouds. Highly interactive features such as touch gestures and intuitive menu actions allow for expeditious exploration of the search results. Other features include drag-and-drop functionality for articles among bubbles, merging nodes, and refining the search …

Overwhelming The Saa System Of Delivery Uavs By Drone Swarming, Barry Lynn Pfaff

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As the Internet continues to replace the brick-and-mortar store as the main place for purchasing goods, web-based companies are looking for ways to reduce the cost of delivering those goods. The use of Unmanned Aerial Vehicles, or UAVs, is one delivery method that is increasingly being used. These UAVs can be programmed with delivery routes and destinations and can complete the job while requiring limited intervention from human controllers. Sense and Avoidance (SAA) systems have recently been incorporated into these UAVs so that they can detect objects in their flight path, reroute the UAV accordingly and operate even more autonomously. …

Fully Transparent Computer Vision Framework For Ship Detection And Tracking In Satellite Imagery, Jason T. Gottweis

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Tracking of ships in satellite imagery is a challenging problem in remote sensing since it requires both object detection and object recognition. Most of the resources available only cover one of these problems and are often filled with machine learning techniques which are costly to train. Additionally, the techniques covered in these resources are often difficult to replicate or may be hard to combine with other solutions to get a full tracking algorithm. The proposed framework offers a transparent and efficient alternative to machine learning approaches and includes preprocessing, detection, and recognition needed for tracking. All components of the framework …

Augment The Multi-Modal Interaction Capabilities Of Hololens Through Networked Sensory Devices, Subhadra Tummalapally

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Augmented Reality (AR) places virtual contents along with real objects to enhance user perception in the physical environment. It is a technology that has shown great potential in many industries such as medicine, education and transportation. AR devices, such as Microsoft HoloLens, come with multi-modal interaction capabilities, such as voice, gesture and gaze, to support intuitive and reliable human-computer interactions. However, HoloLens gesture support is limited to simple gestures like tap, bloom and hold, it stops short to support meaningful interaction through full hand gesture and motion tracking, which may be critical in field operations of various industry practices in …

Determination Of Dose Effects When Including Attenuation Of The Treatment Table Into Treatment Planning Computer Modeling, Abdullah Alshamrany

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During radiation treatment, the patient commonly lies on a horizontal treatment table called a couch. The material used for the couch is chosen during the manufacturing process so as to minimize the effect of the couch on dose delivery, but it still has an effect. In addition to couch attenuation on the beam, the modern approach of using multiple beam angles for dose delivery makes treatment planning in the presence of the couch more challenging. However, the effect of the couch is not always considered when creating treatment plans, generally due to treatment planning software limitations. In this evaluation, the …

Establishing A Quality Assurance Routine For Digital Imaging, Sulaiman Rana Al

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In the clinical medical physics field, Quality Assurance (QA) is a fundamental topic to insure patient safety and effective treatment. In recent years, the imaging hardware for diagnostic x-rays has been shifting to fully digital detectors. However, the quality assurance tests for such detectors in the clinical setting is still under development. In the Medical Imaging Department of Kettering Hospital (Kettering, OH), the currently accepted method of performing QA on detectors is to use an extensive set of tests suggested by the manufacturer. This set of tests requires about 90 minutes, which is too long for daily use. The goal …

A Twitter-Based Study For Understanding Public Reaction On Zika Virus, Roopteja Muppalla

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In recent times, social media platforms like Twitter have become more popular and people have become more interactive and responsive than before. People often react to every news in real-time and within no-time, the information spreads rapidly. Even with viral diseases like Zika, people tend to share their opinions and concerns on social media. This can be leveraged by the health officials to track the disease in real-time thereby reducing the time lag due to traditional surveys. A faster and accurate detection of the disease can allow health officials to understand people's opinion of the disease and take necessary precautions …

A Model For Seasonal Dynamic Networks, Jace D. Robinson

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Sociotechnological and geospatial processes exhibit time varying structure that make insight discovery challenging. This paper presents statistical model of systems with seasonal dynamics, modeled as a dynamic network, to address this challenge. It assumes the probability of edge formations depend on a type assigned to incident nodes and the current time. Time dependencies are modeled by unique seasonal processes. The model is studied on several synthetic and real datasets. Superior fidelity of this model on seasonal datasets compared to existing network models, while being able to remain equally accurate for networks with randomly changing structure, is shown. The model is …

Geophysical Exploration Of The Upper Crust Underlying North-Central Indiana: New Insight Into The Eastern Granite-Rhyolite Province, Michael Ray Green

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This study analyzes ten 2D seismic lines donated by CountryMark together with potential field data to examine the upper crustal structure near Wabash, Indiana. These seismic profiles reveal significant relief of the Precambrian Unconformity and prominent upper crustal reflections. The Precambrian Unconformity interpreted from the unmigrated stacked seismic sections is characterized by undulations and bowtie artifacts. Zero offset seismic models constructed using profiles of the exposed Precambrian Unconformity across the Eastern Granite-Rhyolite Province outcrops of the St. Francois Mountains feature the same seismic expression. The upper crust below the Precambrian Unconformity on the Countrymark seismic sections is also characterized by …