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Full-Text Articles in Physical Sciences and Mathematics

Collaboration And Co-Management Ahead Of Permitting: Understanding How Actors And Their Interactions Lead To Non-Optimal Shoreline Projects, Juita-Elena (Wie) Yusuf, Mariana Saitgalina, Michelle Covi Jan 2026

Collaboration And Co-Management Ahead Of Permitting: Understanding How Actors And Their Interactions Lead To Non-Optimal Shoreline Projects, Juita-Elena (Wie) Yusuf, Mariana Saitgalina, Michelle Covi

School of Public Service Faculty Publications

Living shorelines are widely promoted as nature-based solutions to coastal erosion and wetland protection, yet hardened shoreline structures continue to dominate even in jurisdictions with explicit policy mandates prioritizing living shorelines. In this research, we examine why non-optimal shoreline modification outcomes persist in Virginia (USA) despite a regulatory framework designed to promote ecological alternatives. We use primary data from interviews with wetlands board members, marine contractors, and nonprofit organizations and findings from a secondary survey of shoreline property owners to analyze shoreline management as a multi-sector collaborative decision-making process. Findings show that shoreline outcomes are shaped less by individual regulatory …


Designing Ai Systems To Support A Productive-Failure-Based Learning: Insights From Adult Learners On Ai Applications And Ai System Design Principles, Jinhee Kim, Xi Lin, Seongryeong Yu, Rita Detrick Jan 2026

Designing Ai Systems To Support A Productive-Failure-Based Learning: Insights From Adult Learners On Ai Applications And Ai System Design Principles, Jinhee Kim, Xi Lin, Seongryeong Yu, Rita Detrick

STEMPS Faculty Publications

Emerging capabilities of generative artificial intelligence (GenAI) offer significant potential to support productive failure (PF)-based learning, which engages adult learners (ALs) in exploring problems before instruction and learning from their initial attempts. However, the effective use of AI to support multifaceted areas of PF-based learning, including problem generation, exploration, consolidation, and knowledge assembly, is limited. Furthermore, AI design principles to support PF-based learning remain under-researched. This study, therefore, aims to investigate ALs’ perceptions of AI applications in enhancing PF-based learning and to explore the essential design principles of AI systems for PF-based learning. To achieve these aims, the study conducted …


Drivers Of Phytoplankton Bloom Interannual Variability In The Amundsen And Pine Island Polynyas, Guillaume Liniger, Delphine Lannuzel, Sébastien Moreau, Michael S. Dinniman, Peter G. Stutton Jan 2026

Drivers Of Phytoplankton Bloom Interannual Variability In The Amundsen And Pine Island Polynyas, Guillaume Liniger, Delphine Lannuzel, Sébastien Moreau, Michael S. Dinniman, Peter G. Stutton

CCPO Publications

The Amundsen Sea Embayment (ASE) experiences both the highest ice shelf melt rates and the highest biological productivity in West Antarctica. Using 19 years of satellite data and modelling output, we investigate the long-term influence of environmental factors on the phytoplankton bloom in the Amundsen Sea (ASP) and Pine Island (PIP) polynyas. We test the prevailing hypothesis that changes in ice shelf melt rate could drive interannual variability in the polynyas' surface chlorophyll-a (chl a) and Net Primary Productivity (NPP). We find that the interannual variability and long-term change in glacial meltwater may play an important role in …


Results Of The Second Ice Shelf-Ocean Model Intercomparison Project (Isomip+), Claire K. Yung, Xylar S. Asay-Davis, Alistair Adcroft, Christopher Y. S. Bull, Jan De Rydt, Michael S. Dinniman, Benjamin K. Galton-Fenzi, Daniel Goldberg, David E. Gwyther, Robert Hallberg, Matthew Harrison, Tore Hattermann, David M. Holland, Denise Holland, Paul R. Holland, James R. Jordan, Nicolas C. Jourdain, Kazuya Kusahara, Gustavo Marques, Pierre Mathiot, Adele K. Morrison, Yoshihiro Nakayama, Olga Sergienko, Robin S. Smith, Alon Stern, Ralph Timmermann, Qin Zhou Jan 2026

Results Of The Second Ice Shelf-Ocean Model Intercomparison Project (Isomip+), Claire K. Yung, Xylar S. Asay-Davis, Alistair Adcroft, Christopher Y. S. Bull, Jan De Rydt, Michael S. Dinniman, Benjamin K. Galton-Fenzi, Daniel Goldberg, David E. Gwyther, Robert Hallberg, Matthew Harrison, Tore Hattermann, David M. Holland, Denise Holland, Paul R. Holland, James R. Jordan, Nicolas C. Jourdain, Kazuya Kusahara, Gustavo Marques, Pierre Mathiot, Adele K. Morrison, Yoshihiro Nakayama, Olga Sergienko, Robin S. Smith, Alon Stern, Ralph Timmermann, Qin Zhou

CCPO Publications

Ocean-driven basal melting of Antarctic ice shelves plays an important role in the mass loss of the Antarctic Ice Sheet. Ice shelf cavity-resolving ocean models are a valuable tool for understanding ice shelf-ocean interactions and for simulating projections of ice shelf and ocean states under future climate. Designed to assess the current state of ice shelf–ocean modelling, the second Ice Shelf–Ocean Model Intercomparison Project, ISOMIP+, consists of 12 ocean model configurations submitted with a common, idealised experimental setup. Here, we focus on the experiments Ocean0–2 (Asay-Davis et al., 2016), which are ocean models with idealised, static ice …


Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han Jan 2026

Differences In Biologic Clinical Trials For Chronic Rhinosinusitis With Nasal Polyps—Are We Comparing Apples With Oranges?, Marjolein Cornet, Peter W. Hellings, Martin Desrosiers, Martin Wagenmann, Richard Follows, Laura Walrave, Luz Adriana Jimenez, Lee Tombs, Dawn Edwards, Peter Howarth, Joseph K. Han

Department of Otolaryngology (ENT) Faculty Publications

In recent years, several biologics targeting Type 2 inflammation have been developed for treating chronic rhinosinusitis with nasal polyps (CRSwNP). These have been studied in registrational randomized controlled trials (RCTs), which vary in their patient populations, trial design, endpoints, geography, timing, or data-handling processes. While (in)direct treatment comparisons and meta-analyses have been carried out to compare efficacy results from RCTs, often these fail to properly account for these between-study differences. Here, we summarize the key between-study differences that can influence trial outcomes and highlight the resulting challenges faced when comparing outcomes from different Phase III RCTs of biologics in CRSwNP.


Machine Learning-Based Lifetime Prediction Of Lithium Batteries: A Comparative Assessment For Electric Vehicle Applications, Abdelilah Hammou, Raffaele Petrone, Demba Diallo, Boubekeur Tala-Ighil, Philippe Makany Boussiengue, Hicham Chaoui, Hamid Gualous Jan 2026

Machine Learning-Based Lifetime Prediction Of Lithium Batteries: A Comparative Assessment For Electric Vehicle Applications, Abdelilah Hammou, Raffaele Petrone, Demba Diallo, Boubekeur Tala-Ighil, Philippe Makany Boussiengue, Hicham Chaoui, Hamid Gualous

Electrical & Computer Engineering Faculty Publications

This paper evaluates and compares four data-driven methods (Gaussian Process Regression (GPR), echo state network (ESN), gated recurrent unit (GRU), and long short-term memory (LSTM)) for lithium-ion capacity prognostics adapted to electric vehicle conditions. This comparison aims to find the most efficient prognosis method considering two constraints: the limitation of computational power and the unavailability of on-board capacity measurement that requires full charge and discharge conditions. The machine learning models are trained using capacity values estimated under vehicle conditions. The ageing data is collected from cycling tests of two battery chemistries, Lithium Fer Phosphate (LFP) and Nickel Manganese Cobalt (NMC), …


Supporting K-5 Computer Science Integration Through High-Quality Teacher Professional Development, Shanan Chappell Moots, Joanna K. Garner, Joseph A. Brobst, Melani Loney, Lisa Steffian, Jennifer Maeng Jan 2026

Supporting K-5 Computer Science Integration Through High-Quality Teacher Professional Development, Shanan Chappell Moots, Joanna K. Garner, Joseph A. Brobst, Melani Loney, Lisa Steffian, Jennifer Maeng

Center for Educational Partnerships Publications

Workforce development and education leaders have increasingly emphasized the need for high-quality computer science (CS) instruction for K-12 students. Though states have created and mandated the implementation of CS curriculum standards, few in-service teachers have been provided sufficient opportunities to develop CS pedagogical content knowledge and self-efficacy. This study evaluated the effect of a CS integration professional development (PD) program on K-5 teachers' perceptions of their capacity to teach CS and their implementation of CS-integrated lessons using a randomized controlled trial design. Treatment included an intensive online summer institute with school year follow-up. Results indicate statistically significant effects of the …


Clinical Subtypes Of Co-Morbid Insomnia And Obstructive Sleep Apnea (Comisa): Results Of A Cluster Analysis, Yuan Shi, Xujun Feng, Fengyi Hao, Yuru Nie, Yihui Zhang, Zhaohua Chen, Siqi Guan, Larry D. Sanford, Michael V. Vitiello, Xiangdong Tang Jan 2026

Clinical Subtypes Of Co-Morbid Insomnia And Obstructive Sleep Apnea (Comisa): Results Of A Cluster Analysis, Yuan Shi, Xujun Feng, Fengyi Hao, Yuru Nie, Yihui Zhang, Zhaohua Chen, Siqi Guan, Larry D. Sanford, Michael V. Vitiello, Xiangdong Tang

Department of Pathology & Anatomy Faculty Publications

Background

Variations in the bidirectional relationship between obstructive sleep apnea (OSA) and insomnia in co-morbid insomnia and OSA (COMISA) may form distinct subtypes of COMISA, which have not been previously characterized. This study aims to identify and characterize subtypes of COMISA.

Methods

From a community-recruited COMISA cohort 256 individuals who met diagnosis for COMISA were used to identify subtypes using a two-step clustering methodology. Demographics and multidimension clinical characteristics were collected and compared among obtained subtypes. Logistic models were used to evaluate whether these subtypes were associated with cardiometabolic and mental disorders. A clinical cohort of 1816 COMISA patients was …


Understanding Motivations And Health Outcomes Of College-Aged Triathletes During Covid-19: A Mixed-Methods Study, Patrick Wilson, Eddie Hill, Justin Haegele, Xihe Zhu Jan 2026

Understanding Motivations And Health Outcomes Of College-Aged Triathletes During Covid-19: A Mixed-Methods Study, Patrick Wilson, Eddie Hill, Justin Haegele, Xihe Zhu

Human Movement Studies & Special Education Faculty Publications

A triathlon is a multi-sport event that consists of three simultaneous events: swimming, biking, and running. This sport has experienced significant growth in the past few decades, with colleges and universities now participating. This exploratory mixed-methods study examined the motivations and perceived health benefits of college triathletes during the COVID-19 pandemic, using the Means-Ends of Recreation Scale and the Perceived Health Outcomes of Recreation Scale (N = 29), as well as semi-structured interviews (N = 4). Results indicate no difference in motives or health outcomes between male and female survey respondents. The thematic analysis of open-ended interview questions highlighted lived …


Exploring The Synergy Between Very Large Transformer And Lstm Models For Effective Medical Captioning From Videos To Text: The Impact Of Captioning In Healthcare, R. V. Aswiga, Moin Ahmed Zahir Jan 2026

Exploring The Synergy Between Very Large Transformer And Lstm Models For Effective Medical Captioning From Videos To Text: The Impact Of Captioning In Healthcare, R. V. Aswiga, Moin Ahmed Zahir

Data Science Faculty Publications

In today’s rapidly evolving digital landscape, the demand for accurate and contextually relevant subtitles for image and video content, particularly in the medical domain, is increasingly critical. Despite the proliferation of visual data across various platforms, existing captioning systems often struggle due to variations in visual settings, complex temporal relationships, and nuanced semantics. Additionally, challenges such as limited datasets, privacy issues, and specialized annotation requirements make medical image captioning particularly difficult. To tackle these challenges, we investigate cutting-edge deep learning methodologies, specifically Transfer Learning and Transformer models, through a comparative analysis. Specifically, we focus on Transfer Learning through the MedVisionCapturer …


A Hybrid Cnn-Lstm Surrogate Model For Hyper-Resolution Spatiotemporal Flood Forecasting In Norfolk, Virginia, Yidi Wang, Jonathan L. Goodall, Chetan Kumar, Diana Mcspadden, Sergio A. Barbosa, Binata Roy, Ali Shahabi, Navid Tahvildari Jan 2026

A Hybrid Cnn-Lstm Surrogate Model For Hyper-Resolution Spatiotemporal Flood Forecasting In Norfolk, Virginia, Yidi Wang, Jonathan L. Goodall, Chetan Kumar, Diana Mcspadden, Sergio A. Barbosa, Binata Roy, Ali Shahabi, Navid Tahvildari

Data Science Faculty Publications

Study region

Norfolk, Virginia, United States

Study focus

Accurate and timely flood forecasting is essential for enhancing resilience in coastal urban areas in the context of increasing frequency and intensity of rainfall, sea level rise and urbanization. This study presents a hybrid deep learning-based surrogate model that integrates Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) networks to enable real-time spatiotemporal flood forecasting. The model leverages CNN to capture spatial features from inputs such as elevation and Topographic Wetness Index (TWI), while LSTM processes time-series inputs of rainfall and tide data to capture temporal features.

New hydrologic insights for …


The Xpdirc Concept For Next-Generation Dirc Detectors, R. Dzhygadlo, J. Datta, K. Dehmelt, A. Deshpande, T. K. Hemmick, Md. I. Hossain, C. E. Hyde, Y. Ilieva, G. Kalicy, W. J. Llope, P. Nadel-Turonski, C. Schwarz, J. Schwiening, N. Shankman, J. Stevens, N. Wickramaarachchi, C. Woody Jan 2026

The Xpdirc Concept For Next-Generation Dirc Detectors, R. Dzhygadlo, J. Datta, K. Dehmelt, A. Deshpande, T. K. Hemmick, Md. I. Hossain, C. E. Hyde, Y. Ilieva, G. Kalicy, W. J. Llope, P. Nadel-Turonski, C. Schwarz, J. Schwiening, N. Shankman, J. Stevens, N. Wickramaarachchi, C. Woody

Physics Faculty Publications

The next-generation DIRC (xpDIRC) represents a novel detector geometry concept currently being developed for advanced particle identification systems in high-energy physics experiments. Building upon the high-performance DIRC (hpDIRC) designed for the ePIC detector at the Electron-Ion Collider, the xpDIRC introduces a hybrid optical architecture that combines enhanced focusing optics, a wide plate light guide, and a compact expansion volume. Comprehensive Geant4 simulations demonstrate that the xpDIRC hybrid geometry achieves state-of-the-art performance in π/K separation across the entire range of operation.


Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches, Isamu Umeda, Meicen Liu, Jiefu Wang, Yi Zheng, Zhiwu Wang, Jaya Shankar Tumuluru, Sandeep Kumar Jan 2026

Parametric Study Of Yields And Properties Of Corn Stover-Derived Hydrothermal Liquefaction Products By Using Statistical Approaches, Isamu Umeda, Meicen Liu, Jiefu Wang, Yi Zheng, Zhiwu Wang, Jaya Shankar Tumuluru, Sandeep Kumar

Civil & Environmental Engineering Faculty Publications

Hydrothermal liquefaction (HTL) of lignocellulosic biomass produces multiple product fractions, including solid residue (SR), heavy bio-oil (HBO), aqueous phase (AP), and light bio-oil (LBO). This study mainly applied principal component analysis (PCA) and regression modeling to predict AP solution weight, LBO weight and fuel characteristics, and HTL wastewater biodegradability, as well as to improve prediction accuracy for SR and HBO under various operating conditions (temperature: 250–350 °C, residence time: 5–60 min, and the combined solid loading of three batches: 15–45 g). A complementary relationship between SR and AP weights found in PCA enabled the estimation of AP weight based on …


Physics-Based Multi-Hazard Fragility Modeling Of Low-Rise Wood-Frame Buildings Under Hurricane-Induced Wind And Surge, Mumtasirun Nahar, Abdullah M. Braik, Mohammad Syed, Maria Koliou, Petros Sideris Jan 2026

Physics-Based Multi-Hazard Fragility Modeling Of Low-Rise Wood-Frame Buildings Under Hurricane-Induced Wind And Surge, Mumtasirun Nahar, Abdullah M. Braik, Mohammad Syed, Maria Koliou, Petros Sideris

Civil & Environmental Engineering Faculty Publications

Coastal buildings are exposed to concurrent hurricane-induced wind and storm surge, yet their vulnerability is commonly assessed using separate single-hazard models that neglect hazard interaction. This study developed a physics-based finite element framework to evaluate the performance of a low-rise light wood-frame building under simultaneous wind and surge-wave loading. A detailed three-dimensional model was constructed using a sub-assembly strategy that explicitly represented framing members, sheathing systems, and critical connections. Structural response was evaluated across a hazard space defined by wind speed, still-water depth, and flow velocity, and component- and system-level fragility functions were derived using Monte Carlo simulation and generalized …


Gender Differences In The Association Between Adverse Childhood Experiences And Drug Use: Findings From A Community-Based Survey In China, Hongyun Fu, Elizabeth Monk-Turner, Xiushi Yang Jan 2026

Gender Differences In The Association Between Adverse Childhood Experiences And Drug Use: Findings From A Community-Based Survey In China, Hongyun Fu, Elizabeth Monk-Turner, Xiushi Yang

Department of Pediatrics Faculty Publications

Background

While adverse childhood experiences (ACEs) are widely recognized risk factors for behavioral health problems, including drug use, prior research has largely been conducted in Western countries, focused primarily on males, and relied on convenience samples without comparison groups of nonusers. Limited work has examined the impact of ACEs on drug use in non-Western contexts. This study examines gender differences in the relationship between ACEs and drug use in China, using data from a population-based probability sample survey.

Methods:

Cross-sectional data were collected in 2019 from one city in Yunnan Province in Southwest China and one city in Guangdong Province …


Explainable Physics-Based Constraints On Reinforcement Learning For Accelerator Optimization, Jonathan Colen, Malachi Schram, Kishansingh Rajput, Armen Kasparian Jan 2026

Explainable Physics-Based Constraints On Reinforcement Learning For Accelerator Optimization, Jonathan Colen, Malachi Schram, Kishansingh Rajput, Armen Kasparian

Data Science Faculty Publications

We present a reinforcement learning (RL) framework for optimizing particle accelerator experiments that builds explainable physics-based constraints on agent behavior. The goal is to increase transparency and trust by letting users verify that the agent’s decision-making process incorporates suitable physics. Our algorithm uses a learnable surrogate function for physical observables, such as energy, and uses them to fine-tune how actions are chosen. This surrogate can be represented by a neural network or by an interpretable sparse dictionary model. We test our algorithm on a range of particle accelerator optimization environments designed to emulate the Continuous Electron Beam Accelerator Facility at …


Applying Transfer Learning For Street-Scale Nuisance Flood Forecasting In Coastal-Urban Environments, Binata Roy, Jonathan L. Goodall, Diana Mcspadden, Chetan Kumar, Steven Goldenberg, Yidi Wang, Malachi Schram Jan 2026

Applying Transfer Learning For Street-Scale Nuisance Flood Forecasting In Coastal-Urban Environments, Binata Roy, Jonathan L. Goodall, Diana Mcspadden, Chetan Kumar, Steven Goldenberg, Yidi Wang, Malachi Schram

Data Science Faculty Publications

An important challenge with Machine Learning (ML) is its transferability; that is, whether an ML model trained on one set of data can be applied to a second set of data without requiring full retraining of the model. Transfer Learning (TL) addresses this challenge by transferring knowledge learned in the source domain (the data it was trained on) to the target domain (a second set of data that is statistically different but related, which the model was not trained on). This study investigates the use of TL for street-scale nuisance flood forecasting by exploring whether an ML model trained for …


Healthcare Digital Twins: A Methodological Literature Review On Integrating Iot And Ai For Personalized Medicine And Predictive Care, Sara Shahnazinia, Mahsa Tavasoli, Abdolhossein Sarrafzadeh, Ali Karimoddini Jan 2026

Healthcare Digital Twins: A Methodological Literature Review On Integrating Iot And Ai For Personalized Medicine And Predictive Care, Sara Shahnazinia, Mahsa Tavasoli, Abdolhossein Sarrafzadeh, Ali Karimoddini

Electrical & Computer Engineering Faculty Publications

Digital Twin (DT) technology has the potential to revolutionize healthcare delivery and enhance patient outcomes through personalized and precision medicine, simulation models for operations and interventions, and drug discovery. However, successful implementation of DTs in Internet of Things (IoT) and artificial intelligence (AI) healthcare is contingent upon addressing key challenges such as privacy, ethics, and robust data security. This paper presents a methodological literature review of DT applications in healthcare, systematically analyzing the current state of research, key enabling technologies, and implementation challenges. The review summarizes DT categorization approaches (application-based, technology-based, and real-time function-based); delineates core DT components such as …


Gem-Can: A Real-World Dataset Of Can-Bus Attack Scenarios On An Autonomous Vehicle For Intrusion-Detection Research, Mahsa Tavasoli, Abdolhossein Sarrafzadeh, Ali Karimoddini, Tienake Phuapaiboon, Milad Khaleghi, Daniel Tobias Jan 2026

Gem-Can: A Real-World Dataset Of Can-Bus Attack Scenarios On An Autonomous Vehicle For Intrusion-Detection Research, Mahsa Tavasoli, Abdolhossein Sarrafzadeh, Ali Karimoddini, Tienake Phuapaiboon, Milad Khaleghi, Daniel Tobias

Electrical & Computer Engineering Faculty Publications

This paper presents GEM-CAN, a labelled Controller Area Network (CAN) dataset captured from an autonomous GEM e6 platform under both normal operation and controlled cyber-attack conditions.

The dataset contains ∼143 K frames comprising (i) ∼ nominal autonomous operation (∼100k messages), (ii) DoS floods using arbitration ID 0 × 00000000 (∼41 K messages), and (iii) data-tampering injections that reuse legitimate IDs for brake and steering-lock (∼1.3 K messages). Each record includes timestamp, arbitration ID (11/29-bit), DLC, eight payload bytes, and a Normal/Attack label. A companion metadata file enumerates attack windows, PCAN bus-load traces, bitrate, and test conditions. Data were collected with …


Integer-Valued Time Series Model Via Copula-Based Bivariate Skellam Distribution, Mohammed Alqawba, Norou Diawara, Mame Mor Sene Jan 2026

Integer-Valued Time Series Model Via Copula-Based Bivariate Skellam Distribution, Mohammed Alqawba, Norou Diawara, Mame Mor Sene

Mathematics & Statistics Faculty Publications

Time series analysis is crucial for modeling and forecasting diverse real-world phenomena. Traditional models typically assume continuous-valued data; however, many applications involve integer-valued series, often including negative integers. This paper introduces an approach that combines copula theory with the bivariate Skellam distribution to handle such integer-valued data effectively. Copulas are widely recognized for capturing complex dependencies among variables. By integrating copulas, our proposed method respects integer constraints while modeling positive, negative, and temporal dependencies accurately. Through simulation and an empirical study on a real-life example, we demonstrate that our class of models performs well. This approach has broad applicability in …


Wearable Sensor-Based Phase Segmentation Analysis Of Front Crawl Swimming: A Scoping Review, Jonathan Simoes, Samuel Aylward, Daniel Hamze, Daniel James Goble, Daniel M. Russell, Joshua Haworth Jan 2026

Wearable Sensor-Based Phase Segmentation Analysis Of Front Crawl Swimming: A Scoping Review, Jonathan Simoes, Samuel Aylward, Daniel Hamze, Daniel James Goble, Daniel M. Russell, Joshua Haworth

Exercise Science Faculty Publications

Front crawl swimming stroke phase segmentation has historically relied on video analysis, but the development of wearable sensor technology has created new opportunities for automated phase segmentation. This scoping review mapped the available evidence on wearable sensor-based stroke phase segmentation methods in front crawl swimming, following PRISMA-ScR guidelines. A systematic search of SPORTDiscus, Web of Science, and IEEE Xplore conducted from January to June 2026, identified 15 eligible peer-reviewed studies published between 2000 and 2024. The review revealed an emerging field of research that has converged methodologically around inertial measurement units (IMUs) and the Chollet phase segmentation framework while remaining …


Reply To: S. N. Katkuri Et Al. And H. Liu Et Al. On Early And Sustained Improvements In Sense Of Smell With Tezepelumab Treatment In Patients With Chronic Rhinosinusitis With Nasal Polyps (Waypoint), Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose Jan 2026

Reply To: S. N. Katkuri Et Al. And H. Liu Et Al. On Early And Sustained Improvements In Sense Of Smell With Tezepelumab Treatment In Patients With Chronic Rhinosinusitis With Nasal Polyps (Waypoint), Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose

Department of Otolaryngology (ENT) Faculty Publications

[Introduction] We thank Dr. S. N. Katkuri, Dr. H. Liu, and their coauthors [1, 2] for their interest in our recent publication describing the improvements in loss of smell symptoms with tezepelumab versus placebo in patients with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) in the WAYPOINT trial (NCT04851964) [3]. We are grateful for the authors' feedback on the clinical significance of the data presented and their appreciation of the consistency observed across a range of baseline clinical characteristic and demographic subgroups.


Use Of Tezepelumab For Chronic Rhinosinusitis With Nasal Polyps By Eosinophilic Endotype: Waypoint Post-Hoc Analysis, Shigeharu Fujieda, Nobuyoshi Otori, Joseph K. Han, Tadataka Yabuta, Claudia Chen, Claudio Marchese, Andrews Foster, Sandhia S. Ponnarambil, Yun Chan, Brian J. Lipworth Jan 2026

Use Of Tezepelumab For Chronic Rhinosinusitis With Nasal Polyps By Eosinophilic Endotype: Waypoint Post-Hoc Analysis, Shigeharu Fujieda, Nobuyoshi Otori, Joseph K. Han, Tadataka Yabuta, Claudia Chen, Claudio Marchese, Andrews Foster, Sandhia S. Ponnarambil, Yun Chan, Brian J. Lipworth

Department of Otolaryngology (ENT) Faculty Publications

Background

The phase 3 WAYPOINT study (NCT04851964) reported that tezepelumab improved outcomes in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), including nasal polyp size, nasal congestion, and sinonasal symptoms, and reduced the need for surgery and systemic corticosteroids (SCS).

Objective

To evaluate the efficacy and safety of tezepelumab across Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis-defined eosinophilic chronic rhinosinusitis (ECRS) subgroups.

Methods

Adults with severe CRSwNP were randomized to tezepelumab 210 mg or placebo every 4 weeks. Coprimary end points were the change from baseline to week 52 in total Nasal Polyp Score and the biweekly mean Nasal …


Redefining Educational Technology: A Critical Collaborative Inquiry, Aras Bozkurt, Helen Crompton, Robert Farrow, Agnes Kukulska-Hulme, Jon Dron, Richard West, Agnieszka (Aga) Palalas, Matth Bower, Junhong Xiao, Ahmed Tlili, Danah Henriksen, Angelica Pazurek, Henk Huijser, Thomas K. F. Chiu, Petar Jandrić, Katy Jordan, John Curry, Royce Kimmons, Mutlu Cukurova, Thomas Reeves, Gwo-Jen Hwang, Peter Shea, Jason Lodge, Martin Weller, Davy Ng, Tutaleni Iita Asino Jan 2026

Redefining Educational Technology: A Critical Collaborative Inquiry, Aras Bozkurt, Helen Crompton, Robert Farrow, Agnes Kukulska-Hulme, Jon Dron, Richard West, Agnieszka (Aga) Palalas, Matth Bower, Junhong Xiao, Ahmed Tlili, Danah Henriksen, Angelica Pazurek, Henk Huijser, Thomas K. F. Chiu, Petar Jandrić, Katy Jordan, John Curry, Royce Kimmons, Mutlu Cukurova, Thomas Reeves, Gwo-Jen Hwang, Peter Shea, Jason Lodge, Martin Weller, Davy Ng, Tutaleni Iita Asino

STEMPS Faculty Publications

Educational technologists have not settled on a fixed definition of the field and likely never will. However, attempting to define the field helps to understand the epistemological meanings that shape what the field sees, values, and considers worth pursuing. Through a critical historical review spanning over a century, alongside theoretical engagement with the concepts of entanglement and distributed agency, this paper identifies three key insufficiencies in current educational technology frameworks. These are the persistence of an instrumental-facilitative paradigm that treats technology as a resource deployed by human agents; the theoretical dissolution of the pedagogy-technology dichotomy that existing definitions have not …


Evaluating Species At Risk In Data-Limited Fisheries: A Productivity-Susceptibility Analysis For Marine Aquarium Fish, Gabrielle A. Baillargeon, Alice A. Wynn, Jemelyn Grace P. Baldisimo, Michael F. Tlusty, Andrew L. Rhyne Jan 2026

Evaluating Species At Risk In Data-Limited Fisheries: A Productivity-Susceptibility Analysis For Marine Aquarium Fish, Gabrielle A. Baillargeon, Alice A. Wynn, Jemelyn Grace P. Baldisimo, Michael F. Tlusty, Andrew L. Rhyne

Biological Sciences Faculty Publications

The marine aquarium trade (MAT) is a significant global industry harvesting millions of wild-caught, live coral reef fishes for public and private aquaria markets in the United States and Europe annually, while supporting fisher livelihoods in the Indo-Pacific. This diverse and species-rich trade is considered data-limited, creating barriers to quantifying the current and future socio-ecological sustainability of the fishery. We present a revised and expanded productivity–susceptibility analysis (PSA) that serves as a holistic risk assessment to estimate the vulnerability of marine aquarium fish to overfishing. Our global analysis includes 306 species that are actively in trade. Improvements to the PSA …


The Devil Is In The Det[Ai]Ls: Ai Agents, Ghost Students, And The Crisis Of Verified Presence In An Agentic Ai World, Aras Bozkurt, Helen Crompton, Caroline Fell Kurban Jan 2026

The Devil Is In The Det[Ai]Ls: Ai Agents, Ghost Students, And The Crisis Of Verified Presence In An Agentic Ai World, Aras Bozkurt, Helen Crompton, Caroline Fell Kurban

STEMPS Faculty Publications

The transition from reactive Generative Artificial Intelligence (GenAI) to agentic AI systems marks a categorical shift in digital education, moving beyond simple content generation to goal-oriented, autonomous execution. This paper explores the emergence of the “ghost student”: a digital surrogate created by the coupling of Large Language Models (the “mind”) and agentic AI browsers (the “body”). These entities are capable of navigating Learning Management Systems (LMS), engaging with content, and completing assessments with human-like mimicry, often rendering the actual learner’s presence optional. We argue that this phenomenon creates a verification gap that traditional proctoring and detection tools are structurally unable …


Instructional Designers' Reflections On Generative Ai Use For Scenario-Based And Performance-Centered Learning: A Collective Autoethnography, Nour El Houda Maache, Dan V. Dao, Jiyoon Jung, Jayanth Nadheri, Nari Kim, Chikezie Ozuzu, Xinyue Ren Jan 2026

Instructional Designers' Reflections On Generative Ai Use For Scenario-Based And Performance-Centered Learning: A Collective Autoethnography, Nour El Houda Maache, Dan V. Dao, Jiyoon Jung, Jayanth Nadheri, Nari Kim, Chikezie Ozuzu, Xinyue Ren

STEMPS Faculty Publications

This study examines how instructional designer-instructors (IDIs) use and evaluate generative artificial intelligence (GenAI) when designing scenario-based and performance-centered authentic learning in higher education. Using a collective autoethnography (CAE) approach, the study draws on semi-structured interviews and reflective narratives from five IDIs with varied professional experience. Findings indicate that GenAI enhanced design capacity by accelerating scenario development, translating complex content, and supporting scenario-based and performance-based task construction. At the same time, participants reported limitations related to contextual misalignment, output unreliability, and the cognitive demands of prompt refinement. Across cases, effective integration depended on sustained human oversight, disciplinary judgment, and ethical …


Chatgpt In Secondary English Language Learning: Educators' And Students' Literacy, Perceptions, And Experiences, Victoria Brenes, Sierra Outerbridge, Xinyue Ren Jan 2026

Chatgpt In Secondary English Language Learning: Educators' And Students' Literacy, Perceptions, And Experiences, Victoria Brenes, Sierra Outerbridge, Xinyue Ren

STEMPS Faculty Publications

The increasing use of generative artificial intelligence (GenAI) has shown the potential of transforming teaching and learning practices in various educational settings, such as in English language learning (ELL). As English language learners (ELLs) often experience many challenges and barriers in schools in the United States, it is urgent to leverage the educational affordances of GenAI in fostering the effectiveness of ELL. Given the limited research investigating GenAI adoption, especially ChatGPT literacy within K-12 ELL, this convergent mixed methods research aims to investigate students' and teachers’ perceptions of using ChatGPT and their ChatGPT literacy in secondary ELL contexts. We will …


A Two-Stage Changepoint-Copula Framework For Non-Stationary Count Time Series: Application To Tropical Cyclones, Md Iqbal Hossain, Norou Diawara Jan 2026

A Two-Stage Changepoint-Copula Framework For Non-Stationary Count Time Series: Application To Tropical Cyclones, Md Iqbal Hossain, Norou Diawara

Mathematics & Statistics Faculty Publications

Cross-basin tropical cyclone variability may exhibit complex, non-linear dependence structures influenced by large-scale climate modes and potential regime shifts. Reliance on traditional linear correlation measures without accounting for structural changes can therefore lead to misleading interpretations of global storm relationships. This study investigates the regional dependence structures of tropical cyclone counts across six major ocean basins (NA, ENP, WNP, NI, SI, and SP) from 1980 to 2024. We adopt a two-stage analytical framework integrating changepoint detection and copula modeling to address non-stationarity in both marginal distributions and dependence structures. First, we identify a significant structural break in the year 2000 …


Climate Change Impacts On Hydrology In The Upper James Watershed, Imiya Mudiyanselage Chathuranika, Dalya Ismael Jan 2026

Climate Change Impacts On Hydrology In The Upper James Watershed, Imiya Mudiyanselage Chathuranika, Dalya Ismael

Engineering Technology Faculty Publications

Hydrological modeling of the Upper James Watershed (UJW), Virginia, is critical for predicting water availability, flood management, agriculture, ecosystem protection, and hydropower production under increasing climate change. The Hydrologic Engineering Center-Hydrologic Modeling System (HEC-HMS) is applied to evaluate climate change impacts on key hydrological components within the watershed. Future climate conditions were assessed for the near (NF: 2026-2050), mid (MF: 2051-2075), and far (FF: 2076-2100) periods using three Global Climate Models (GCMs) under Shared Socioeconomic Pathways SSP 2-4.5 and SSP 5-8.5. Climate data were bias-corrected using the Linear Scaling Method (LSM) and used to drive the HEC-HMS model. Results project …