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Articles 3391 - 3420 of 3676

Full-Text Articles in Physical Sciences and Mathematics

Fast Scalable Visualization Techniques For Interactive Billion-Particle Walkthrough, Xinlian Liu Jan 2002

Fast Scalable Visualization Techniques For Interactive Billion-Particle Walkthrough, Xinlian Liu

LSU Doctoral Dissertations

This research develops a comprehensive framework for interactive walkthrough involving one billion particles in an immersive virtual environment to enable interrogative visualization of large atomistic simulation data. As a mixture of scientific and engineering approaches, the framework is based on four key techniques: adaptive data compression based on space-filling curves, octree-based visibility and occlusion culling, predictive caching based on machine learning, and scalable data reduction based on parallel and distributed processing. In terms of parallel rendering, this system combines functional parallelism, data parallelism, and temporal parallelism to improve interactivity. The visualization framework will be applicable not only to material simulation, …

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Artificial Peptides Containing Ca,A- Disubstituted Amino Acids: Synthesis, Conformational Studies, And Application As Β-Strand Mimics, Yanwen Fu Jan 2002

Artificial Peptides Containing Ca,A- Disubstituted Amino Acids: Synthesis, Conformational Studies, And Application As Β-Strand Mimics, Yanwen Fu

LSU Doctoral Dissertations

Short peptides containing Cα,α-dipropylglycine (Dpg) at alternating sequence positions were synthesized and examined for conformational behavior. Peptide assembly was performed using Fmoc-solid-phase chemistry where the coupling with PyAOP could be significantly enhanced at elevated temperature. Circular dichroism (CD) and NMR conformational studies revealed that incorporation of Dpg residues induced folded structures into peptides. It was observed that Dpg residues adopted helical conformation in a helix-promoting sequence. The resulting helical structure was comprised of consecutive β-turns whose structure was stabilized by salt bridge in aqueous solution. In this study, the preparation of sterically and polyfunctional Cα,α-disubstituted amino …

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Outcrop To Subsurface Stratigraphy Of The Pennsylvanian Hermosa Group Southern Paradox Basin U.S.A., Alan Lee Brown Jan 2002

Outcrop To Subsurface Stratigraphy Of The Pennsylvanian Hermosa Group Southern Paradox Basin U.S.A., Alan Lee Brown

LSU Doctoral Dissertations

Pennsylvanian (Desmoinesian) sedimentary rocks within the Paradox Basin Four Corners area of the western United States afford a unique opportunity to study the development of sedimentary successions in a complex marine to nonmarine depositional setting. The close association of thick intervals of nonmarine fan-delta facies adjacent to and in time equivalent position to marine carbonate-evaporite facies suggests complex relationships between the factors affecting deposition. Development of an effective scheme to differentiate the depositional signatures from within these sedimentary successions is the primary goal of this study. To achieve this goal, two objectives were pursued. The first was to calibrate the …

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Electronic And Structural Properties Of Rare Gas Cation Clusters, Jose Alejandro Gascon Jan 2002

Electronic And Structural Properties Of Rare Gas Cation Clusters, Jose Alejandro Gascon

LSU Doctoral Dissertations

We study structure and ground and excited state properties of rare gas cation clusters, Rg+N, for N=3-60. The main goal is to understand how the positive charge is delocalized over the cluster and the relationship between cluster geometry and delocalization. He+N, Ar+N, and Xe+N are selected as representatives of the rare gas elements. We perform Monte Carlo simulations to obtain finite temperature properties of the energy spectrum. The Hamiltonian of the system is based on a semi-empirical model whose parameters are obtained through the fitting of experimental and calculated …

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Hydrodynamics And Freshwater Diversion Within Barataria Basin, Dongho Park Jan 2002

Hydrodynamics And Freshwater Diversion Within Barataria Basin, Dongho Park

LSU Doctoral Dissertations

In order to understand the physical processes in the Barataria estuary, a previously developed two-dimensional, depth-integrated hydrodynamic model is applied to simulate estuarine processes. The equations for conservation of mass and momentum predict specific physical processes when forced by tidal and salinity variations at the open boundaries, wind forcing patterns, precipitation and evaporation over the model domain, and freshwater runoff as point sources. This study is focused on examining the impact of freshwater dispersion from the freshwater sources. Thus, a hydrologic model was developed to estimate runoff. Furthermore grid size was reduced, a new advective code added, and baroclinic effects …

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On Properties Of Linear Control Systems On Lie Groups, Fabiana Cardetti Jan 2002

On Properties Of Linear Control Systems On Lie Groups, Fabiana Cardetti

LSU Doctoral Dissertations

In this work we study controllability properties of linear control systems on Lie groups as introduced by Ayala and Tirao in [AT99]. A linear control system _x0006_Σ Lie group G is defined by x' = X(x) + Σkj=1 ujYj(x), where the drift vector field X is an infinitesimal automorphism, uj are piecewise constant functions, and the control vectors Yj are left-invariant vector fields. Properties for the flow of the infinitesimal automorphism X and for the reachable set defined by _x0006_Σ are presented in Chapter 3. Under a condition similar to the Kalman …

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Synthesis And Properties Of Novel Macrocycles And Related Chromophoric Benzenoid Compounds, Jorge O. Escobedo Cordova Jan 2002

Synthesis And Properties Of Novel Macrocycles And Related Chromophoric Benzenoid Compounds, Jorge O. Escobedo Cordova

LSU Doctoral Dissertations

The synthesis and properties of some macrocyclic compounds of interest are presented. Resorcinarenes with functionalized conjugated rigid rods made of oligo-p-phenylenes would lead to an entirely new class of functional, soluble, well-defined architectures impacting a variety of multidisciplinary research efforts. The general synthetic design described in this document could be readly extrapolated to include other electronic systems such as heteroaromatics and polyenes. An extensive collaborative study of chromophore formation in resorcinarene solutions is also described here. The study reveals that upon oxidation, the reversible conversion to acyclic precursors occur first, and then these precursors undergo oxidation to quinoid-type compounds (xanthenes). …

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The Synthesis Of New Biotin Derivatives And Their Bioactivity, Latisha Chanette Johnson Jan 2002

The Synthesis Of New Biotin Derivatives And Their Bioactivity, Latisha Chanette Johnson

LSU Master's Theses

Biotin is an essential growth factor found in all living cells. It functions as a cofactor for a group of coenzymes that catalyze transcarboxylation, decarboxylation, and carboxylation reactions. Acetyl CoA carboxylase catalyzes the first committed and regulated step in fatty acid synthesis in which malonyl CoA is the product. The biotin-dependent enzyme is found in all animals, plants, and bacteria. We studied the kinetic and structural aspects of acetyl CoA carboxylase, and in 1999 we reported the bioactivity and total synthesis of a unique first generation biotin-derived inhibitor of acetyl CoA carboxylase, 1(BP1). Kinetic studies on the activity of E. …

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Discrete Mathematics Topics In The Secondary School Curriculum, Aimee Beth Boyd Jan 2002

Discrete Mathematics Topics In The Secondary School Curriculum, Aimee Beth Boyd

LSU Master's Theses

This thesis discusses two topics of discrete mathematics in a manner suitable for presentation at a secondary-school level. The introduction outlines the benefits of including discrete mathematics in the secondary-school curriculum. The two chapters which follow include detailed treatment of the two selected topics: the Traveling Salesman Problem and RSA encryption. The discussion of the Traveling Salesman Problem consists of introduction to the problem through several real-life scenarios, followed by a discussion of various methods for solving the problem. We discuss exact and approximate algorithms together with their computational complexity and practical limitations. The discussion of RSA encryption begins with …

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Group Automorphisms And The Decomposition Of Plancherel Measures, David Slay Jan 2002

Group Automorphisms And The Decomposition Of Plancherel Measures, David Slay

LSU Doctoral Dissertations

In this paper, a natural action of the automorphisms of a group on the space of irreducible unitary representations is used to decompose the Plancherel measure on the dual space as an integral of measures on homogeneous spaces. Explicit decompositions are obtained for the cases of free 2 and 3-step nilpotent Lie groups. These results are obtained using direct integral decompositions, induced representations, the Mackey Machine, and measure theory on homogeneous spaces.

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Nonlinear Dynamics In Nuclear Structure, Guergana Stoianova Stoitcheva Jan 2002

Nonlinear Dynamics In Nuclear Structure, Guergana Stoianova Stoitcheva

LSU Doctoral Dissertations

New collective coordinates that describe the deformation of atomic nuclei in terms of solitary waves (rotons) that are solutions of an underlying nonlinear liquid drop dynamics are introduced. The rotons, which are highly localized surface excitations, are shown to be intelligent states of an underlying angular momentum algebra, and furthermore, to adiabatically decouple from the rotational motion of the nucleus. An expansion of the roton profile in terms of surface multipoles shows that although the quadrupole mode (&lambda= 2) dominates, there are significant contributions from other even multipoles with &lambda= 4, 6, 8, etc. The picture of nuclear deformation that …

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Sediment Transport In Wind-Exposed Shallow, Vegetated Aquatic Systems, Allen Michael Teeter Jan 2002

Sediment Transport In Wind-Exposed Shallow, Vegetated Aquatic Systems, Allen Michael Teeter

LSU Doctoral Dissertations

Ecosystems with submersed vegetation are relatively shallow, physically stable and of moderate hydrodynamic energy. Submersed vegetation affect hydrodynamic friction for currents and waves resulting in increased overall frictional loss. Seagrasses shelter the sediment bed and reduce wind-wave resuspension. Bed sheltering factors were estimated from previous flume data on Laguna Madre seagrass species. Data from Laguna Madre indicate that total suspended material levels for bare areas are about an order of magnitude higher than some areas with submersed vegetation. Waves in Laguna Madre at depths less than 2 m were found to be smaller than those expected for the same non-dimensional …

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Barium And Lithium In Foraminifera: Glacial-Interglacial Changes In The North Atlantic, Jenney M. Hall Jan 2002

Barium And Lithium In Foraminifera: Glacial-Interglacial Changes In The North Atlantic, Jenney M. Hall

LSU Doctoral Dissertations

The trace element content of calcareous foraminifera provides a powerful tool to the study of glacial-interglacial changes in the physical and chemical properties of the ocean. Foraminifera incorporate barium in direct proportion to its concentration in seawater. Using barium as a nutrient proxy, Ba/Ca in benthic Planulina wuellerstorfi is used to reconstruct changes in thermocline ventilation and mid-depth circulation in the North Atlantic during the last glacial and deglacial time. Rivers are concentrated in barium compared to surface seawater. Therefore, barium in planktonic Neogloboquadrina pachyderma is used to identify deglacial meltwater in the Arctic Ocean. Foraminiferal Li/Ca was analyzed to …

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Molecular Dynamics Simulations Of Adhesion And Nanoidentation Of Gallium Arsenide, Francis Brent Neal, Jr. Jan 2002

Molecular Dynamics Simulations Of Adhesion And Nanoidentation Of Gallium Arsenide, Francis Brent Neal, Jr.

LSU Doctoral Dissertations

The purpose of this dissertation is to investigate the nanoscale hardness of gallium arsenide thin films and the elastic-plastic behavior of gallium arsenide under an indenter. These investigations were carried out using molecular dynamics (MD) simulations. The simulations are based on interatomic potentials that accurately reproduce many properties of bulk GaAs. The MD simulations performed required scalable and efficient algorithms for implementation on large parallel computers. Nanoindentation simulations were performed using an ideal indenter that was held rigid during the simulation. To reduce the transient effects due to loading, the traversal of the indenter was interrupted periodically to allow the …

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Techniques And Algorithms For Immersive And Interactive Visualization Of Large Datasets, Ashish Sharma Jan 2002

Techniques And Algorithms For Immersive And Interactive Visualization Of Large Datasets, Ashish Sharma

LSU Master's Theses

Advances in computing power have made it possible for scientists to perform atomistic simulations of material systems that range in size, from a few hundred thousand atoms to one billion atoms. An immersive and interactive walkthrough of such datasets is an ideal method for exploring and understanding the complex material processes in these simulations. However rendering such large datasets at interactive frame rates is a major challenge. A scalable visualization platform is developed that is scalable and allows interactive exploration in an immersive, virtual environment. The system uses an octree based data management system that forms the core of the …

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Mitigation Strategies For The Removal Of Rinsate Organics And Lithium-Based Dyes From Textile Effluents, Kathryn W. Huddle Jan 2002

Mitigation Strategies For The Removal Of Rinsate Organics And Lithium-Based Dyes From Textile Effluents, Kathryn W. Huddle

LSU Master's Theses

Governmental agencies have set regulatory values on the concentration of dye-related color that can be released in textile mill effluents. A proprietary biotic and abiotic technology treatment train was built at a candidate facility in northwestern Georgia to reduce the organic content and dye-related color content in the textile mill’s effluent. Laboratory experimentation began with bench scale 4 L immobilized microbe (IMBR) bioreactor tests to biologically treat primary wastewater streams, namely skein dye and space dye, from this candidate facility. The biological treatment reduced the organic content levels, expressed as chemical oxygen demand (COD), from 3185±30 to 290±20 mg/L (COD …

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Feeding Habits Of Blacktip Sharks, Carcharhinus Limbatus, And Atlantic Sharpnose Sharks, Rhizoprionodon Terraenovae, In Louisiana Coastal Waters, Kevin Patrick Barry Jan 2002

Feeding Habits Of Blacktip Sharks, Carcharhinus Limbatus, And Atlantic Sharpnose Sharks, Rhizoprionodon Terraenovae, In Louisiana Coastal Waters, Kevin Patrick Barry

LSU Master's Theses

Little is known regarding the feeding behavior of many shark species. Even less is known about shark feeding habits in Louisiana coastal waters. The stomach contents of gillnet-captured blacktip sharks (n=356), Carcharhinus limbatus, and Atlantic sharpnose sharks (n=55), Rhizoprionodon terraenovae, were examined in this study. Roughly half of the blacktip stomachs (52%) and sharpnose stomachs (45%) contained prey items. The primary prey item in terms of percent number, occurrence, and weight for blacktips and sharpnose was the gulf menhaden, Brevoortia patronus. Both blacktips and sharpnose appear to mainly be piscivores; however, no members of Sciaenidae, the most common family of …

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Sedimentation Rates And Metal Retention In An Urban Louisiana Swamp, Renee Lynn Sanders Jan 2002

Sedimentation Rates And Metal Retention In An Urban Louisiana Swamp, Renee Lynn Sanders

LSU Master's Theses

Naturally vegetated areas converted to urban uses increases impervious surfaces in a watershed with corresponding increases in nutrient, sediment, and metal loadings to downstream ecosystems. Wetlands mitigate detrimental impacts by transforming or retaining pollutants. Current and historic sedimentation and metal retention rates were measured in an urban, depressional wetland in Baton Rouge, Louisiana to evaluate landscape position and watershed development on these processes. Sedimentation disks, feldspar marker horizons, and Cs137 analyses were used in three distinct landscape positions. Inflow channels had the highest elevation and water velocity while the interior was located in the lowest elevations with the longest hydroperiod. …

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Significance Of Variations Among Ancient Deltaic Deposits In The Arkoma Basin, North-Central Arkansas, Christine Michelle Wright Jan 2002

Significance Of Variations Among Ancient Deltaic Deposits In The Arkoma Basin, North-Central Arkansas, Christine Michelle Wright

LSU Master's Theses

The Arkoma Basin is one of several foreland basins formed in association with the Ouachita orogeny. The Arkoma Basin has been studied in depth with regard to stratigraphy, depositional environments, structure and its relationship to the Appalachian-Ouachita orogenic event. This study focuses on the variability of the deltaic deposits within the Arkoma Basin and the significance of the variables to both the delta complex and the overall tectonic setting. The specific characteristics to be investigated include variations in paleocurrent directions, bed thicknesses, bed geometries, organic contents, sand/shale ratios, mineral assemblages and fossil assemblages. In the case of the Arkoma deltaic …

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The Importance Of Zooplankton In The Diets Of Blue Runner (Caranx Crysos) Near Offshore Petroleum Platforms In The Northern Gulf Of Mexico, Sean Francis Keenan Jan 2002

The Importance Of Zooplankton In The Diets Of Blue Runner (Caranx Crysos) Near Offshore Petroleum Platforms In The Northern Gulf Of Mexico, Sean Francis Keenan

LSU Master's Theses

Blue runner (Caranx crysos), common around offshore petroleum platforms in the Gulf of Mexico, were found to forage extensively on meso- and macro-zooplankton during the summer months. Larval decapods and stomatopods, hyperiid amphipods, pteropods, and larval and juvenile fishes were common components of their diet. Feeding periodicity results suggest that blue runner around platforms were capable of feeding throughout the night at the same intensity as the day. Size selectivity indicated that larger prey, such as fish were consumed during the night and smaller decapod crustaceans were consumed during the day. Blue runner collected from open waters away from platforms …

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Characterization Of An In Vivo Diode Dosimetry System For Clinical Use, Kai Huang Jan 2002

Characterization Of An In Vivo Diode Dosimetry System For Clinical Use, Kai Huang

LSU Master's Theses

An in vivo dosimetry system that uses p-type semiconductor diodes with buildup caps was characterized for clinical use. The dose per pulse dependence was investigated. This was done by altering the SSD, field size and wedge for photons, and by altering SSD and cone size for electrons. The off-axis correction and effect of changing repetition rate were also investigated. A model was made to fit the measured diode correction factors.

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A Comparison Of Storm Hydrographs From Small Urban Watersheds With Different Land Use Patterns In Baton Rouge, Josey Wade Walker Jan 2002

A Comparison Of Storm Hydrographs From Small Urban Watersheds With Different Land Use Patterns In Baton Rouge, Josey Wade Walker

LSU Master's Theses

Statistics gathered by FEMA indicate that nine of ten federal disasters are related to flooding. Research has demonstrated that increases in flooding can be contributed to urbanization or the construction of new residential and commercial developments (Anderson, 1970; Arnold & Gibbons, 1996; Putnam, 1972). New development has two main problems associated with it. First is the increase in impervious surfaces due to new parking lots, buildings, and streets (Booth & Leavitt, 1999; Seaburn, 1969). Second is the elimination of natural vegetation, which reduces evapotranspiration and lowers the soil’s ability to absorb precipitation (Hewlett, 1982). This study first demonstrates the relationship …

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Distributary Mouth Bar Formation And Channel Bifurcation In The Wax Lake Delta, Atchafalaya Bay, Louisiana, Anton J. Dumars Jan 2002

Distributary Mouth Bar Formation And Channel Bifurcation In The Wax Lake Delta, Atchafalaya Bay, Louisiana, Anton J. Dumars

LSU Master's Theses

The Mississippi River has undergone at least seven cyclic avulsions during the Holocene epoch. The latest avulsion, down the Atchafalaya River into the Gulf of Mexico, has produced two bayhead deltas prograding into Atchafalaya Bay. The Wax Lake Delta, typical of other Mississippi sub-deltas, has a natural anastomosing channel pattern. In contrast, the Atchafalaya Delta, situated in the eastern side of the Bay, has experienced sporadic and limited growth due to the dredging of a navigation channel below natural depth. Channel bifurcation, and sediment transport processes and responses, were investigated in the Wax Lake Delta, using channel flow velocities, suspended …

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Analyzing The Education Mandate Of Title X: The Lead-Based Paint Reduction Act Of 1992, William Troy Roussel Jan 2002

Analyzing The Education Mandate Of Title X: The Lead-Based Paint Reduction Act Of 1992, William Troy Roussel

LSU Master's Theses

The Environmental Protection Agency appropriates 400 million dollars in grant funding under the authority of Title X: Residential Lead-based Paint Hazard Reduction Act of 1992. The education mandate of Title X states that the federal government must build an infrastructure to educate the public, real estate professionals, and contractors, to name a few, on the hazards of lead-based paint. A survey was developed to assess the effectiveness of the Title X education mandate. Contractors in the City of New Orleans were surveyed to assess their knowledge of the act and the hazards of lead-based paint before attending an 8-hour training …

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The Radiation-Induced Degradation Of Poly(Diene Sulfones) As X-Ray Resists, Gina Marie Calderon Jan 2002

The Radiation-Induced Degradation Of Poly(Diene Sulfones) As X-Ray Resists, Gina Marie Calderon

LSU Master's Theses

The microlithographic process, essential in the fabrication of silicon chip integrated circuits, uses high-energy radiation to transfer a pattern onto a thin film of polymer resist. Pattern transfer occurs by modifying the properties (solubility or volatility) of the polymer film exposed to radiation. Poly(olefin sulfones) exhibit a high sensitivity to x-rays, which is a desirable property for polymer resists, but typically undergo a glass transition around room temperature and a thermal degradation at moderate temperatures. The thermal properties of the poly(olefin sulfones) reduce the processing latitude for industrial microelectronics applications. Poly(unsaturated olefin sulfones) containing a carbon-carbon double bond in the …

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Early-Middle Tertiary Deposition In The Corque Syncline, Altiplano Plateau, Bolivia, Brian A. Hampton Jan 2002

Early-Middle Tertiary Deposition In The Corque Syncline, Altiplano Plateau, Bolivia, Brian A. Hampton

LSU Master's Theses

Tertiary age rocks are exposed along north-south trending structures throughout the hinterland Altiplano plateau, central Andes. The east limb of the Corque syncline (SW Bolivia) contains the thickest and most continuous successions of late Eocene–Oligocene age non-marine strata (Potoco Formation) on the Altiplano. The Potoco is up to ~6500 m thick and has continuous exposure >103 km2 making it the thickest and most extensive remnant of the mid-Tertiary Altiplano basin. Basin fill during late Eocene–Oligocene time remains the most rapid and sustained period of deposition since Andean orogenesis, recording a long-term sediment accumulation rate of ~0.5 mm/my. The …

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Overpressuring, Diagenesis, And Fluid Flow At The Matagorda Island 519 Field, Offshore Texas, Gulf Of Mexico, Kera Gautreau Spears Jan 2002

Overpressuring, Diagenesis, And Fluid Flow At The Matagorda Island 519 Field, Offshore Texas, Gulf Of Mexico, Kera Gautreau Spears

LSU Master's Theses

The relations between overpressuring, diagenesis, and fluid flow in sedimentary basins are complex and multifaceted. The Matagorda Island 519 field (MI 519), offshore Texas, provides an excellent area for investigating some of these relations. The top of overpressure at MI 519 occurs at a depth of 3.5 to 3.8 km in a Lower Miocene deltaic sequence. On the basis of log-derived lithostratigraphy, the pressure seal does not appear to be lithologic in origin. Geochemical, mineralogical, and cuttings information indicate instead that the precipitation of diagenetic calcite and possibly quartz cements has been the major factor in seal development. Stratigraphic variation …

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Nutrient Reserves Of Lesser Scaup During Spring Migration In The Mississippi Flyway: A Test Of The Spring Condition Hypothesis, Michael J. Anteau Jan 2002

Nutrient Reserves Of Lesser Scaup During Spring Migration In The Mississippi Flyway: A Test Of The Spring Condition Hypothesis, Michael J. Anteau

LSU Master's Theses

The continental scaup population (lesser [Aythya affinis] and greater scaup [A. marila] combined) has declined markedly during the past 20 years, and has remained below the population goal of the North American Waterfowl Management Plan since 1985. One hypothesis explaining the scaup population decline states that reproductive success has decreased because females presently are arriving on breeding areas in poorer condition than that historically (Spring Condition Hypothesis [SCH]). I tested the SCH by comparing fresh body masses (FBMs) and nutrient reserves (lipid, protein, and mineral) of lesser scaup at 4 locations (Louisiana, Illinois, Minnesota, and Manitoba) in the Mississippi Flyway …

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Denitrification Potential Of Sediment From A Future Mississippi River Diversion Site In Louisiana, Roy Ryuta Iwai Jan 2002

Denitrification Potential Of Sediment From A Future Mississippi River Diversion Site In Louisiana, Roy Ryuta Iwai

LSU Master's Theses

Denitrification potential was determined in surface sediment from Lake Cataouatche, the receiving basin for a future Mississippi River diversion located in the northern portion of the Barataria Basin estuary. Nitrate removal and denitrification was measured in the laboratory using static sediment microcosms flooded with lake water. Dissolved potassium nitrate (KNO3) was added to the microcosms to achieve: 1) an initial nitrate concentration similar to the mean Mississippi River concentration (~1.4 mg NO3-N l-1), and, 2) a high initial nitrate concentration to elicit a denitrification potential (~50 mg NO3-N l-1). Denitrification …

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The Ligase Detection Reaction: The Evolution Of A Mutation Detection Strategy, Hannah D. Farquar Jan 2002

The Ligase Detection Reaction: The Evolution Of A Mutation Detection Strategy, Hannah D. Farquar

LSU Doctoral Dissertations

Early detection of genetic mutations is important for control of diseases such as cancer and Alzheimer's. Early detection requires methods that detect small amounts of mutated DNA in very large amounts of normal or wild type DNA. One method to detect mutated DNA is the ligase detection reaction (LDR). Since its inception LDR has evolved greatly from a simple detection reaction after PCR amplification to PCR/RE/LDR, a scheme which uses nucleoside base analogs in PCR to convert wild type sequences to sequences containing restriction endonuclease (RE) sites which can then be cleaved leaving only mutant sequences for detection by LDR. …

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