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Articles 2281 - 2310 of 3436

Full-Text Articles in Physical Sciences and Mathematics

An Exploration Of Topologies And Communication In Large Particle Swarms, Matthew Gardner, Andrew Mcnabb, Kevin Seppi May 2009

An Exploration Of Topologies And Communication In Large Particle Swarms, Matthew Gardner, Andrew Mcnabb, Kevin Seppi

Faculty Publications

Particle Swarm Optimization (PSO) has typically been used with small swarms of about 50 particles. However, PSO is more efficiently parallelized with large swarms. We formally describe existing topologies and identify variations which are better suited to large swarms in both sequential and parallel computing environments. We examine the performance of PSO for benchmark functions with respect to swarm size and topology. We develop and demonstrate a new PSO variant which leverages the unique strengths of large swarms. “Hearsay PSO” allows for information to flow quickly through the swarm, even with very loosely connected topologies. These loosely connected topologies are …

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Easemail: Easy Accessible Secure Email, Ryan B. Segeberg May 2009

Easemail: Easy Accessible Secure Email, Ryan B. Segeberg

Theses and Dissertations

Traditional email encryption methods are difficult to set up, as they require senders to obtain a message recipient's public key before a secure communication can be sent. Easy Accessible Secure Email (EASEmail) addresses the key establishment and exchange issues of encrypted email by using a lightweight symmetric key server. Users can send a secure email without establishing or exchanging keys with the recipient in advance. With usability as its primary goal, EASEmail strives to bring usable secure email communication to the masses.

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Synthesis And Evaluation Of Stimulatory Properties Of Glycolipids For Natural Killer T Cells, Xiangtian Long May 2009

Synthesis And Evaluation Of Stimulatory Properties Of Glycolipids For Natural Killer T Cells, Xiangtian Long

Theses and Dissertations

Natural killer T cells (NKT cells) are a subset of T cells. They regulate a wide range of diseases including infection, tumor growth, and autoimmune diseases, through recognizing glycolipid antigens in the context of CD1d. An understanding of the scope of glycolipid antigens would facilitate use of this cell type in controlling immune responses. Till today, a lysosomal glycolipid, isoglobotrihexosylceramide (iGb3), is the only natural glycolipid that has been found to be recognized by both human and mouse NKT cells. To elucidate the molecular basis of this specific recognition, iGb3 variants were designed and prepared: i) replacement of the C26 …

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Ionic Selectivity In L-Type Calcium Channels By Electrostatics And Hard-Core Repulsion, Dezso Boda, Douglas Henderson, Monika Valisko, Bob Eisenberg, Dirk Gillespie Apr 2009

Ionic Selectivity In L-Type Calcium Channels By Electrostatics And Hard-Core Repulsion, Dezso Boda, Douglas Henderson, Monika Valisko, Bob Eisenberg, Dirk Gillespie

Faculty Publications

A physical model of selective "ion binding" in the L-type calcium channel is constructed, and consequences of the model are compared with experimental data. This reduced model treats only ions and the carboxylate oxygens of the EEEE locus explicitly and restricts interactions to hard-core repulsion and ion–ion and ion–dielectric electrostatic forces. The structural atoms provide a flexible environment for passing cations, thus resulting in a self-organized induced-fit model of the selectivity filter. Experimental conditions involving binary mixtures of alkali and/or alkaline earth metal ions are computed using equilibrium Monte Carlo simulations in the grand canonical ensemble. The model pore rejects …

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Uav Intelligent Path Planning For Wilderness Search And Rescue, Rongbin Lin Apr 2009

Uav Intelligent Path Planning For Wilderness Search And Rescue, Rongbin Lin

Theses and Dissertations

In Wilderness Search and Rescue (WiSAR), the incident commander (IC) creates a probability distribution map of the likely location of the missing person. This map is important because it guides the IC in allocating search resources and coordinating efforts, but it often depends almost exclusively on prior experience and subjective judgment. We propose a Bayesian model that utilizes publicly available terrain features data to help model lost-person behaviors. This approach enables domain experts to encode uncertainty in their prior estimations and also make it possible to incorporate human-behavior data collected in the form of posterior distributions, which are used to …

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Development Of An Adaptive Equalization Algorithm Using Acoustic Energy Density, Panu Tapani Puikkonen Apr 2009

Development Of An Adaptive Equalization Algorithm Using Acoustic Energy Density, Panu Tapani Puikkonen

Theses and Dissertations

Sound pressure equalization of audio signals using digital signal processors has been a subject of ongoing study for many years. The traditional approach is to equalize sound at a point in a listening environment, but because of its specific dependence on the room frequency response between a source and receiver position, this equalization generally causes the spectral response to worsen significantly at other locations in the room. This work presents both a time-invariant and a time-varying implementation of an adaptive acoustic energy density equalization filter for a one-dimensional sound field. Energy density equalization addresses the aforementioned challenge and others that …

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Synthesis Of 2,4,5-Triaminocyclohexane Carboxylic Acid As A Novel 2-Deoxystreptamine Mimetic, Sarah Elizabeth Roberts Apr 2009

Synthesis Of 2,4,5-Triaminocyclohexane Carboxylic Acid As A Novel 2-Deoxystreptamine Mimetic, Sarah Elizabeth Roberts

Theses and Dissertations

RNAs have become increasingly recognized as possible drug targets due to their involvement in important biochemical functions, as well as their unique but well-defined structures. Recently published crystal structures depict the binding of a series of aminoglycosides- or more specifically- 2-deoxystretamine (2-DOS), the most preserved central scaffold of aminoglycosides, to a conserved 5'-GU-3'region on their target RNAs. A novel unnatural γ-amino acid, 1, has been synthesized using 2-deoxystreptamine as a template through structure-based rational design. The unnatural amino acid has been designed to replace a glycosidic linkage with an amide bond, which may limit the promiscuous binding characteristics of aminoglycosides …

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Progressive Spatial Networks, Samuel Curren Apr 2009

Progressive Spatial Networks, Samuel Curren

Theses and Dissertations

Digital street and trail maps are typically represented by an interconnected network of path segments. These spatial networks are used in map creation, route planning, and geo-location. Consumer GPS devices have become popular as a method of collecting data for use in spatial networks. Existing methods for creating spatial networks either require extensive hand editing or use inefficient algorithms that require re-computation when adding new data to an existing network. I demonstrate a method for creating and maintaining spatial networks that allows for incremental updates without complete re-computation. I also demonstrate how spatial limits on data set growth allows networks …

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Xprime: A Method Incorporating Expert Prior Information Into Motif Exploration, Rachel Lynn Poulsen Apr 2009

Xprime: A Method Incorporating Expert Prior Information Into Motif Exploration, Rachel Lynn Poulsen

Theses and Dissertations

One of the primary goals of active research in molecular biology is to better understand the process of transcription regulation. An important objective in understanding transcription is identifying transcription factors that directly regulate target genes. Identifying these transcription factors is a key step toward eliminating genetic diseases or disease susceptibilities that are encoded inside deoxyribonucleic acid (DNA). There is much uncertainty and variation associated with transcription factor binding sites, requiring these sites to be represented stochastically. Although typically each transcription factor prefers to bind to a specific DNA word, it can bind to different variations of that DNA word. In …

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State Of Secure Application Development For 802.15.4, Janell Armstrong Apr 2009

State Of Secure Application Development For 802.15.4, Janell Armstrong

Theses and Dissertations

A wireless sensor network consists of small, limited-resource embedded systems exchanging environment data and activating controls. These networks can be deployed in hostile environments to monitor wildlife habitats, implemented in factories to locate mobile equipment, and installed in home environments to optimize the use of utilities. Each of these scenarios requires network security to protect the network data. The IEEE 802.15.4 standard is designed for WSN communication, yet the standard states that it is not responsible for defining the initialization, distribution, updating, or management of network public keys. Individuals seeking to research security topics will find that there are many …

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Role Of Molecular Chaperones In G Protein B5-Regulator Of G Protein Signaling Dimer Assembly And G Protein By Dimer Specificity, Alyson Cerny Howlett Apr 2009

Role Of Molecular Chaperones In G Protein B5-Regulator Of G Protein Signaling Dimer Assembly And G Protein By Dimer Specificity, Alyson Cerny Howlett

Theses and Dissertations

In order for G protein signaling to occur, the G protein heterotrimer must be assembled from its nascent polypeptides. The most difficult step in this process is the formation of the Gβγ dimer from the free subunits since both are unstable in the absence of the other. Recent studies have shown that phosducin-like protein (PhLP1) works as a co-chaperone with the cytosolic chaperonin complex (CCT) to fold Gβ and mediate its interaction with Gγ. However, these studies did not address questions concerning the scope of PhLP1 and CCT-mediated Gβγ assembly, which are important questions given that there are four Gβs …

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Impact Of Spherical Probe Scattering On Estimation Of Acoustic Vector Quantities. (A), Curtis P. Wiederhold, Kent L. Gee, Derek C. Thomas, Scott D. Sommerfeldt, Jonathan D. Blotter Apr 2009

Impact Of Spherical Probe Scattering On Estimation Of Acoustic Vector Quantities. (A), Curtis P. Wiederhold, Kent L. Gee, Derek C. Thomas, Scott D. Sommerfeldt, Jonathan D. Blotter

Faculty Publications

Multimicrophone probes are often used to measure energy-based acoustical quantities. In some cases, these probes consist of microphones mounted on the surface of a sphere, which, due to the high level of symmetry, permits scattering effects to be better characterized. Scattering of a plane wave incident on a rigid sphere has been modeled to observe how particle velocity and intensity calculations are affected by the presence of the sphere. These effects have been investigated for the traditional "finite-difference" method and a recently developed "wave vector" estimation method. In the computer model, 3-D surface plots were made showing the calculated error …

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Test Case Generation Using Model Checking For Software Components Deployed Into New Environments, Tonglaga Bao, Michael D. Jones Apr 2009

Test Case Generation Using Model Checking For Software Components Deployed Into New Environments, Tonglaga Bao, Michael D. Jones

Faculty Publications

In this paper, we show how to generate test cases for a component deployed into a new software environment. This problem is important for software engineers who need to deploy a component into a new environment. Most existing model based testing approaches generate models from high level specifications. This leaves a semantic gap between the high level specification and the actual implementation. Furthermore, the high level specification often needs to be manually translated into a model, which is a time consuming and error prone process. We propose generating the model automatically by abstracting the source code of the component using …

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Topics In Analytic Number Theory, Kevin James Powell Mar 2009

Topics In Analytic Number Theory, Kevin James Powell

Theses and Dissertations

The thesis is in two parts. The first part is the paper “The Distribution of k-free integers” that my advisor, Dr. Roger Baker, and I submitted in February 2009. The reader will note that I have inserted additional commentary and explanations which appear in smaller text. Dr. Baker and I improved the asymptotic formula for the number of k-free integers less than x by taking advantage of exponential sum techniques developed since the 1980's. Both of us made substantial contributions to the paper. I discovered the exponent in the error term for the cases k=3,4, and worked the case k=3 …

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Verifying Abstract Components Within Concrete Software Environments, Tonglaga Bao Mar 2009

Verifying Abstract Components Within Concrete Software Environments, Tonglaga Bao

Theses and Dissertations

In order to model check a software component which is not a standalone program, we need a model of the software which completes the program. This problem is important for software engineers who need to deploy an existing component into a new environment. The model is typically generated by abstracting the surrounding software environment in which the component will be executed. However, abstracting the surrounding software is a difficult and error-prone task, particularly when the surrounding software is a complex software artifact which can not be easily abstracted. In this dissertation, we present a new approach to the problem by …

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Functionalization, Characterization, And Applications Of Diamond Particles, Modification Of Planar Silicon, And Chemoetrics Analysis Of Ms Data, Li Yang Mar 2009

Functionalization, Characterization, And Applications Of Diamond Particles, Modification Of Planar Silicon, And Chemoetrics Analysis Of Ms Data, Li Yang

Theses and Dissertations

In spite of the stablility (lack of reactivity) of diamond powder, I have developed a method for tethering alkyl chains and polymers to deuterium/hydrogen-terminated diamond. One method is through ether linkages via thermolysis of di-tert-amyl peroxide (DTAP). This reaction with DTAP has also been applied to grow polymers on the diamond surface. The other method is atom transfer radical polymerization (ATRP), which was applied to grow polystyrene at the surface of diamond. Both polystyrene-modified diamond and sulfonated polystyrene-modified diamond can be prepared by either method, and can be used for solid phase extraction. Diamond stationary phases are stable under basic …

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The First Attachment And Post-Functionalization Of Polybutadiene And Thio-Click Functionalized Polybutadiene On H-Terminated Si(111), Todd Devere Wickard Mar 2009

The First Attachment And Post-Functionalization Of Polybutadiene And Thio-Click Functionalized Polybutadiene On H-Terminated Si(111), Todd Devere Wickard

Theses and Dissertations

I report the attachment of polymers with pendant vinyl groups to hydrogen-terminated silicon(111) (Si(111)-H) under mild conditions. 1,2-addition polybutadiene (Mw 3200-3500) was attached to Si(111)-H at room temperature with visible light. I also report the partial functionalization, in solution, of 1,2-addition polybutadiene with various thiols using thiol-click chemistry. These compounds bind to Si(111)-H via visible light activation. The partially functionalized polybutadienes allow further functionalization at the surface through unreacted carbon-carbon double bonds. Surfaces were characterized with contact angle goniometry, spectroscopic ellipsometry, X-ray photoelectron spectroscopy (XPS), time-of-flight secondary ion mass spectrometry (ToF-SIMS), and atomic force microscopy (AFM).

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Combined Visible And Infrared Video For Use In Wilderness Search And Rescue, Nathan D. Rasmussen Mar 2009

Combined Visible And Infrared Video For Use In Wilderness Search And Rescue, Nathan D. Rasmussen

Theses and Dissertations

Mini Unmanned Aerial Vehicles (mUAVs) have the potential to be a great asset to Wilderness Search and Rescue groups by providing a bird's eye view of the search area. These vehicles can carry a variety of sensors to better understand the world below. This paper proposes using both Infrared (IR) and Visible Spectrum cameras on a mUAV for Wilderness Search and Rescue. It details a method for combining the color and heat information from these two cameras into a single fused display to reduce needed screen space for remote field use. To align the video frames for fusion, a method …

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Resonant Microwave Cavity For 8.5-12 Ghz Optically Detected Electron Spin Resonance With Simultaneous Nuclear Magnetic Resonance, John S. Colton, L. R. Wienkes Mar 2009

Resonant Microwave Cavity For 8.5-12 Ghz Optically Detected Electron Spin Resonance With Simultaneous Nuclear Magnetic Resonance, John S. Colton, L. R. Wienkes

Faculty Publications

We present a newly developed microwave resonant cavity for use in optically detected magnetic resonance (ODMR) experiments. The cylindrical quasi-TE 011 mode cavity is designed to fit in a 1 in. magnet bore to allow the sample to be optically accessed and to have an adjustable resonant frequency between 8.5 and 12 GHz. The cavity uses cylinders of high dielectric material, so-called "dielectric resonators," in a double-stacked configuration to determine the resonant frequency. Wires in a pseudo-Helmholtz configuration are incorporated into the cavity to provide frequencies for simultaneous nuclear magnetic resonance (NMR). The system was tested by measuring cavity absorption …

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Alternating Links And Subdivision Rules, Brian Craig Rushton Mar 2009

Alternating Links And Subdivision Rules, Brian Craig Rushton

Theses and Dissertations

The study of geometric group theory has suggested several theorems related to subdivision tilings that have a natural hyperbolic structure. However, few examples exist. We construct subdivision tilings for the complement of every nonsingular, prime alternating link and all torus links, and explore some of their properties and applications. Several examples are exhibited with color coding of tiles.

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The 20-Minute Genealogist: A Context-Preservation Metaphor For Assisted Family History Research, Charles D. Knutson, Jonathan Krein Mar 2009

The 20-Minute Genealogist: A Context-Preservation Metaphor For Assisted Family History Research, Charles D. Knutson, Jonathan Krein

Faculty Publications

What can you possibly do to be productive as a family history researcher in 20 minutes per week? Our studies suggest that currently the answer is, “Nothing.” In 20 minutes a would-be researcher can’t even remember what happened last week, let alone what they were planning to do next. The 20-Minute Genealogist is a powerful metaphor within which software solutions must consider context preservation as the fundamental domain of the system, thus freeing the researcher to do research while the software manages the tasks that computers do best. Two survey-based studies were conducted that indicate a significant disconnect between the …

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Measuring Skill Importance In Women's Soccer And Volleyball, Michelle L. Allan Mar 2009

Measuring Skill Importance In Women's Soccer And Volleyball, Michelle L. Allan

Theses and Dissertations

The purpose of this study is to demonstrate how to measure skill importance for two sports: soccer and volleyball. A division I women's soccer team filmed each home game during a competitive season. Every defensive, dribbling, first touch, and passing skill was rated and recorded for each team. It was noted whether each sequence of plays led to a successful shot. A hierarchical Bayesian logistic regression model is implemented to determine how the performance of the skill affects the probability of a successful shot. A division I women's volleyball team rated each skill (serve, pass, set, etc.) and recorded rally …

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Super-Resolution Via Image Recapture And Bayesian Effect Modeling, Neil B. Toronto Mar 2009

Super-Resolution Via Image Recapture And Bayesian Effect Modeling, Neil B. Toronto

Theses and Dissertations

The goal of super-resolution is to increase not only the size of an image, but also its apparent resolution, making the result more plausible to human viewers. Many super-resolution methods do well at modest magnification factors, but even the best suffer from boundary and gradient artifacts at high magnification factors. This thesis presents Bayesian edge inference (BEI), a novel method grounded in Bayesian inference that does not suffer from these artifacts and remains competitive in published objective quality measures. BEI works by modeling the image capture process explicitly, including any downsampling, and modeling a fictional recapture process, which together allow …

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Variable Uplift From Quaternary Folding Along The Northern Coast Of East Timor, Based On U-Series Age Determinations Of Coral Terraces, Nicole L. Cox Mar 2009

Variable Uplift From Quaternary Folding Along The Northern Coast Of East Timor, Based On U-Series Age Determinations Of Coral Terraces, Nicole L. Cox

Theses and Dissertations

Surveys of emergent terraces and U-series ages for ten sites along the coast of East Timor provide estimates of late Quaternary differential vertical strain in the most mature region of the Banda Arc-continent collision complex. Over a distance of ~180 km vertical displacement rates vary between 0.0 and 1.6 meters per 1000 years for the last 150,000 years. Two models of terrace formation (constructional and erosional) are applied to interpret terrace ages from coral ages and to estimate uplift rates. The highest uplift rates are from three sites over a distance of 15 km along the coast. Uplift rates were …

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Characterizing The Statistical Properties And Global Distribution Of Dansgaard-Oeschger Events, Andrea Michelle Thomas Mar 2009

Characterizing The Statistical Properties And Global Distribution Of Dansgaard-Oeschger Events, Andrea Michelle Thomas

Theses and Dissertations

Ice core records from Greenland have shown times of rapid warming during the most recent glacial period, called Dansgaard-Oeschger (D-O) events. D-O events are important to our understanding of both past climate systems and modern climate volatility. In this paper, we present new approaches for statistically evaluating the existence of cyclicity in D-O events and the possible lagged correlation between the Greenland and Antarctica temperature records. Specifically, we consider permutation testing and bootstrapping methodologies for assessing the cyclicity of D-O events and the correlation between the Greenland and Antarctica records. We find that there is not enough evidence to conclude …

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A Dynamic Attribute-Based Data Filtering And Recovery Scheme For Web Information Processing, Amit Ahuja, Yiu-Kai D. Ng Mar 2009

A Dynamic Attribute-Based Data Filtering And Recovery Scheme For Web Information Processing, Amit Ahuja, Yiu-Kai D. Ng

Faculty Publications

Web data being transmitted over a network channel on the Internet with excessive amount of data causes data processing problems, which include selectively choosing useful information to be retained for various data applications. In this paper, we present an approach for filtering less-informative attribute data from a source Website. A scheme for filtering attributes, instead of tuples (records), from a Website becomes imperative, since filtering a complete tuple would lead to filtering some informative, as well as less-informative, attribute data in the tuple. Since filtered data at the source Website may be of interest to the user at the destination …

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Polymer Microfluidic Devices For Bioanalysis, Xuefei Sun Feb 2009

Polymer Microfluidic Devices For Bioanalysis, Xuefei Sun

Theses and Dissertations

Polymeric microchips have received increasing attention in chemical analysis because polymers have attractive properties, such as low cost, ease of fabrication, biocompatibility and high flexibility. However, commercial polymers usually exhibit analyte adsorption on their surfaces, which can interfere with microfluidic transport in, for example, chemical separations such as chromatography or electrophoresis. Usually, surface modification is required to eliminate this problem. To perform stable and durable surface modification, a new polymer, poly(methyl methacrylate-co-glycidyl methacrylate) (PGMAMMA) was prepared for microchip fabrication, which provides epoxy groups on the surface. Whole surface atom transfer radical polymerization (ATRP) and in-channel ATRP approaches were employed to …

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A Unified Approach To Gpu-Accelerated Aerial Video Enhancement Techniques, Stephen Thayn Cluff Feb 2009

A Unified Approach To Gpu-Accelerated Aerial Video Enhancement Techniques, Stephen Thayn Cluff

Theses and Dissertations

Video from aerial surveillance can provide a rich source of data for analysts. From the time-critical perspective of wilderness search and rescue operations, information extracted from aerial videos can mean the difference between a successful search and an unsuccessful search. When using low-cost, payload-limited mini-UAVs, as opposed to more expensive platforms, several challenges arise, including jittery video, narrow fields of view, low resolution, and limited time on screen for key features. These challenges make it difficult for analysts to extract key information in a timely manner. Traditional approaches may address some of these issues, but no existing system effectively addresses …

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Survival Analysis With High-Dimensional Covariates: An Application In Microarray Studies, David Engler, Yi Li Feb 2009

Survival Analysis With High-Dimensional Covariates: An Application In Microarray Studies, David Engler, Yi Li

Faculty Publications

Use of microarray technology often leads to high-dimensional and low-sample size (HDLSS) data settings. A variety of approaches have been proposed for variable selection in this context. However, only a small number of these have been adapted for time-to-event data where censoring is present. Among standard variable selection methods shown both to have good predictive accuracy and to be computationally efficient is the elastic net penalization approach. In this paper, adaptations of the elastic net approach are presented for variable selection both under the Cox proportional hazards model and under an accelerated failure time (AFT) model. Assessment of the two …

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Quasi-Anosov Diffeomorphisms Of 3-Manifolds, Todd L. Fisher, Hertz M. Rodriguez Feb 2009

Quasi-Anosov Diffeomorphisms Of 3-Manifolds, Todd L. Fisher, Hertz M. Rodriguez

Faculty Publications

In 1969, Hirsch posed the following problem: given a diffeomorphism f:N → N and a compact invariant hyperbolic set Λ of f, describe the topology of Λ and the dynamics of f restricted to Λ. We solve the problem where Λ=M^3 is a closed 3-manifold: if M^3 is orientable, then it is a connected sum of tori and handles; otherwise it is a connected sum of tori and handles quotiented by involutions.

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