Physical Sciences and Mathematics Commons^™

Optimized Peptide Nanomaterials As Delivery Vehicles For Hydrophobic Metal-Based Anticancer Agents, Yaron Marciano

Dissertations, Theses, and Capstone Projects

Enzyme-responsive materials have been well explored, particularly as therapeutic and diagnostic agents. In this thesis we demonstrate that anionic self-assembling peptides can be utilized as delivery vehicles for metal-based hydrophobic payloads. The tunability of the system is highlighted as well as the increase in cytotoxicity and selectivity in vitro. The rapid degradation of peptides in cell media may lead to the formation of new peptide-drug bioconjugates with increased activity and selectivity. The physiological stability of these peptide delivery vehicles has been optimized by capping the N-terminus with an acetyl group. This simple backbone modification was shown to not prevent self-assembly, …

Unlocking Potential: The School-To-Prison Pipeline For Students With Disabilities, Navena F. Chaitoo

Dissertations, Theses, and Capstone Projects

This research uses quasi-experimental, matched sampling to examine the school-to-prison pipeline for students with disabilities using data from the National Longitudinal Study of Adolescent to Adult Health. This study presents novel insights into an at-risk group that has faced disproportionate rates of school discipline and incarceration. The study finds school suspension to be associated with future involvement in the criminal legal system and lower educational attainment. Disability was not found to mediate the relationship between suspension and future involvement in the criminal legal system or the relationship between suspension and academic outcomes. However, disability was found to be a statistically …

A Stronger Strong Schottky Lemma For Euclidean Buildings, Michael E. Ferguson

Dissertations, Theses, and Capstone Projects

We provide a criterion for two hyperbolic isometries of a Euclidean building to generate a free group of rank two. In particular, we extend the application of a Strong Schottky Lemma to buildings given by Alperin, Farb and Noskov. We then use this extension to obtain an infinite family of matrices that generate a free group of rank two. In doing so, we also introduce an algorithm that terminates in finite time if the lemma is applicable for pairs of certain kinds of matrices acting on the Euclidean building for the special linear group over certain discretely valued fields.

One-Loop Corrections To Dihadron Production In Dis At Small X, Filip Bergabo

Dissertations, Theses, and Capstone Projects

We calculate the one-loop corrections to dihadron production in Deep Inelastic Scattering (DIS) at small x using the Color Glass Condensate formalism. We show that all UV and soft singularities cancel while the collinear divergences are absorbed into quark and anti quark-hadron fragmentation functions. Rapidity divergences lead to JIMWLK evolution of dipoles and quadrupoles describing multiple-scatterings of the quark anti-quark dipole on the target proton/nucleus. The resulting cross section is finite and can be used for phenomenological studies of dihadron angular correlations at small x in a future Electron-Ion Collider (EIC).

Naming Venus: An Exploration Of Goddesses, Heroines, And Famous Women, Kavya Beheraj

Dissertations, Theses, and Capstone Projects

Humans have been observing and romanticizing Venus for more than 5,000 years. However, mapping its surface has nearly always been impossible, since the planet is shrouded in thick clouds. A breakthrough came just fifty years ago with the invention of radar imaging, leading to the discovery (and naming) of hundreds of new features in a relatively short length of time.

The rapid naming of Venus is a case study on the impact of planetary nomenclature — the process of naming features on other worlds. While the act of naming streamlines communication and humanizes alien landscapes, it is subject to bias, …

A Quantum Approach To Language Modeling, Constantijn Van Der Poel

Dissertations, Theses, and Capstone Projects

This dissertation consists of six chapters. . . Chapter 1: We introduce language modeling, outline the software used for this thesis, and discuss related work. Chapter 2: We will unpack the transition from classical to quantum probabilities, as well as motivate their use in building a model to understand language-like datasets. Chapter 3: We motivate the Motzkin dataset, the models we will be investigating, as well as the necessary algorithms to do calculations with them. Chapter 4: We investigate our models’ sensitivity to various hyperparameters. Chapter 5: We compare the performance and robustness of the models. Chapter 6: We conclude …

Social Impacts Of Robotics On The Labor And Employment Market, Kelvin Espinal

Dissertations, Theses, and Capstone Projects

Robotics have been introduced into the workplace to perform tasks that human beings have traditionally fulfilled. Complementing or substituting human labor with robotics eliminates human involvement in functions attributable to hazardous environments, heavy lifting, toxic substances, and repetitive low-level tasks. On the other hand, they are meant to be more efficient and cost-effective, saving money, time, and labor. However, since the introduction of robotics in the workforce, societal opposition has been towards this branch of technology in fear of losing employment, wages, and purpose.

Previous studies have reported an overarching societal fear that adopting robotics in the workplace and industry …

Beam-Based Target Alignment For Mu2e, Helenka Casler

Dissertations, Theses, and Capstone Projects

The Mu2e Experiment is a precision experiment at Fermi National Accelerator Laboratory, searching for charged lepton flavor violation (CLFV) in the conversion of a muon to an electron in the presence of an atomic nucleus. In order to achieve the expected single-event sensitivity of 3 × 10^-17 , Mu2e will require an intense muon beam, generated via pion decay. These pions are the product of a proton beam striking a radiatively-cooled tungsten target. In order to maximize pion production and prevent target failure, the beam will have to be aligned with the target center to within 0.5 mm. The …

Electromagnetic Theory And Applications, Nicholas Madamopoulos, George Kliros

Open Educational Resources

This book intends to provide both the fundamentals of Electromagnetics but also some practical applications of the concepts covered. Having taught electromagnetics for several years, the authors feel that many times the field of electromagnetics comes as “old” and often times students do not appreciate the concepts and their importance in everyday applications. The authors intend to accompany the EM concepts with life applications. Hence, students may see the direct impact of the knowledge they acquire through the study of the field of electromagnetics and better appreciate the field.

Combinatorics Syllabus, Tugce Ozdemir

Open Educational Resources

No abstract provided.

Muon-Electron Scattering At Nnlo, A. Broggio, T. Engel, Andrea Ferroglia, M. K. Mandal, P. Mastrolia, M. Rocco, J. Ronca, A. Signer, W. J. Torres Bobadilla, Y. Ulrich, M. Zoller

Publications and Research

We present the first calculation of the complete set of NNLO QED corrections for muon-electron scattering. This includes leptonic, non-perturbative hadronic, and photonic contributions. All fermionic corrections as well as the photonic subset that only corrects the electron or the muon line are included with full mass dependence. The genuine four-point two-loop topologies are computed as an expansion in the small electron mass, taking into account both, logarithmically enhanced as well as constant mass effects using massification. A fast and stable implementation of the numerically delicate real-virtual contribution is achieved by combining OPENLOOPS with next-to-soft stabilisation. All matrix elements are …

The Water, Ji Kim

Open Educational Resources

Water is everywhere, thus, we tend to take it for granted. However, access to clean water has been inequitable; climate change is threatening the sea water level, causing the acidification of ocean water. In this project, we will investigate the environmental and social issues related to clean water and its impacts on our life by reading articles, watching videos, and exploring activities.

Towards An Unsupervised Bayesian Network Pipeline For Explainable Prediction, Decision Making And Discovery, Daniel Mallia

Theses and Dissertations

An unsupervised learning pipeline for discrete Bayesian networks is proposed to facilitate prediction, decision making, discovery of patterns, and transparency in challenging real-world AI applications, and contend with data limitations. We explore methods for discretizing data, and notably apply the pipeline to prediction and prevention of preterm birth.

Introduction, Raffi T. Khatchadourian

Open Educational Resources

No abstract provided.

Reengineering And Refactoring, Raffi T. Khatchadourian

Open Educational Resources

No abstract provided.

Models For Decision-Making - Second Edition, Steven Cosares, Fred Rispoli

Open Educational Resources

Decision-Making often refers to a multi-stage process that starts with some form of introspection or reflection about a situation in which a person or group of people find themselves. These ruminations usually lead to series of questions that need to be answered, or to a set of data that needs to be collected and analyzed, or to some calculations that need to be performed before someone can be in a position to make informed decisions and take appropriate actions.

We provide some simple examples of Quantitative Models, which are often found in a decision-making situation. We focus on the use …

Review Java Basics In 2 Weeks (Slides), Shoshana Marcus

Open Educational Resources

No abstract provided.

Cp6200 Javaprogramming2 Oer - Oop Assignment - Item And Shopping Cart Classes, Shoshana Marcus

Open Educational Resources

No abstract provided.

Astr 1: General Astronomy, David Goldberg

Open Educational Resources

No abstract provided.

Phys 275: Intro To Scientific Computing, David Goldberg

Open Educational Resources

No abstract provided.

Math 301: Abstract Algebra I, Nicholas Vlamis

Open Educational Resources

No abstract provided.

Pakistan, India And The Indus River Basin, Muquadas Ilyas

Dissertations and Theses

Water is a fundamental need of all living things. The right to clean water is classified as a human right under United Nations Resolution 64/292.As such it is the responsibility of governments to ensure its citizens are not deprived of this essential resource. In doing so, effective water management is crucial to provide clean water that is accessible to everyone regardless of any challenges such as geographical constraints or political disputes. This thesis explores the water management efforts of Pakistan and India. These countries are facing a water crisis, whereby numerous citizens have died due to dehydration and diseases contracted …

R-Symmetries And Curvature Constraints In A-Twisted Heterotic Landau–Ginzburg Models, Richard S. Garavuso

Publications and Research

In this paper, we discuss various aspects of a class of A-twisted heterotic Landau–Ginzburg models on a Kähler variety X. We provide a classification of the R-symmetries in these models which allow the A-twist to be implemented, focusing on the case in which the gauge bundle is either a deformation of the tangent bundle of X or a deformation of a sub-bundle of the tangent bundle of X. Some anomaly-free examples are provided. The curvature constraint imposed by supersymmetry in these models when the superpotential is not holomorphic is reviewed. Constraints of this nature have been used to establish properties …

Impact Melt Rocks From The Late Paleocene Hiawatha Impact Structure, Northwest Greenland, William R. Hyde, Adam A. Garde, Nynke Keulen, Sebastian N. Malkki, Steven J. Jaret, Tod Waight, Pierre Beck, Iain Mcdonald, Nicolaj K. Larsen

Publications and Research

Impact melt rocks formed during hypervelocity impact events are ideal for studying impact structures. Here, we describe impact melt rock samples collected proximal to the 31 km wide 58 Ma Hiawatha impact structure, northwest Greenland, which is completely covered by the Greenland Ice Sheet. The melt rocks contain diagnostic shock indicators (e.g., planar deformation features [PDF] in quartz and shocked zircon) and form three groups based on melt textures and chemistry: (i) hypocrystalline, (ii) glassy, and (iii) carbonate-based melt rocks. The exposed foreland directly in front of the structure consists of metasedimentary successions and igneous plutons; however, the carbonate-based impactites …

Understanding The Impacts Of Freshwater Fluxes On The Biogeochemistry Of The Coastal Arctic: A Case Study Of Prudhoe Bay, Francesca Lingo

Dissertations and Theses

The Arctic region, undergoing significant environmental changes due to rapid warming, faces alterations in air temperatures, melting permafrost, declining sea ice, and changes in riverine inputs. These shifts have profound implications for Arctic coastal ecology and biogeochemical cycles. This study, focusing on Alaska's North Slope, explores the influence of freshwater fluxes on water optical properties, vital for accurate satellite remote sensing interpretations. Our approach combined field measurements, existing data, and satellite remote sensing retrievals to identify biogeochemical gradients and their seasonal and interannual variations. A novel finding was the unique CDOM composition in Prudhoe Bay, characterized by a lower molecular …

Fine Characterization Of Leafing Phenology In The Brazilian Atlantic Forest By Optical And Microwave Remote Sensing, James B. Bell

Dissertations and Theses

Tropical forests provide important ecosystem functions in the global biosphere, but they remain among the most poorly understood elements of land surface models, especially with regard to their seasonal dynamics. For instance, in seasonally dry forests, the pattern of the annual green-up in their canopies closely follows annual patterns of rainfall. The same, however, does not occur in wet forest canopies which are dominated by evergreen trees. In the latter, water is not scarce enough to limit leaf photosynthetic function. Canopy leafing phenology in these forests is therefore poorly characterized by optical remote sensing methods which are not sensitive to …

Advancing The Accuracy Of Watershed Analysis Across Diverse Hydrometeorological And Geologic Regimes Via Classification And Analysis Of Gpm-Imerg Products, Jake M. Longenecker

Dissertations and Theses

The analysis and protection of watersheds, along with spring water resources, depend on the accurate identification of catchments. Building on previous research that correlated spring hydrographs with high-resolution, satellite-based Global Precipitation Measurement – Integrated Multi-satellitE Retrievals for GPM (GPM-IMERG) data, I improve the speed and accuracy of catchment identification and hydrodynamic characterization via an enhanced Empirically Constrained Hydrologic Operation (ECHO) algorithm. This research (1) establishes optimal parameter inputs for the algorithm to enable reliable identification of source point-locations, (2) removes human in-the-loop processing, and thus reduce potential operator bias, and (3) explores the potential for using a limited dataset of …

Cp 6200 Java Programming 2 Syllabus (Oer), Shoshana Marcus

Open Educational Resources

No abstract provided.

Cp6200 Javaprogramming2 Oer - Oop Course Project, Shoshana Marcus

Open Educational Resources

No abstract provided.

Perspectives On Determinism In Quantum Mechanics: Born, Bohm, And The “Quantal Newtonian” Laws, Viraht Sahni

Publications and Research

Quantum mechanics has a deterministic Schrödinger equation for the wave function. The Göttingen–Copenhagen statistical interpretation is based on the Born Rule that interprets the wave function as a “probability amplitude.” A precept of this interpretation is the lack of determinism in quantum mechanics. The Bohm interpretation is that the wave function is a source of a field experienced by the electrons, thereby attributing determinism to quantum theory. In this paper, we present a new perspective on such determinism. The ideas are based on the equations of motion or “Quantal Newtonian” Laws obeyed by each electron. These Laws, derived from …