Physical Sciences and Mathematics Commons^™

Error Analysis Of A Fully Discrete Projection Method For Magnetohydrodynamic System, Qianqian Ding, Xiaoming He, Xiaonian Long, Shipeng Mao

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we develop and analyze a finite element projection method for magnetohydrodynamics equations in Lipschitz domain. A fully discrete scheme based on Euler semi-implicit method is proposed, in which continuous elements are used to approximate the Navier–Stokes equations and H(curl) conforming Nédélec edge elements are used to approximate the magnetic equation. One key point of the projection method is to be compatible with two different spaces for calculating velocity, which leads one to obtain the pressure by solving a Poisson equation. The results show that the proposed projection scheme meets a discrete energy stability. In addition, with the …

Error Analysis Of A Fully Discrete Projection Method For Magnetohydrodynamic System, Qianqian Ding, Xiaoming He, Xiaonian Long, Shipeng Mao

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we develop and analyze a finite element projection method for magnetohydrodynamics equations in Lipschitz domain. A fully discrete scheme based on Euler semi-implicit method is proposed, in which continuous elements are used to approximate the Navier–Stokes equations and H(curl) conforming Nédélec edge elements are used to approximate the magnetic equation. One key point of the projection method is to be compatible with two different spaces for calculating velocity, which leads one to obtain the pressure by solving a Poisson equation. The results show that the proposed projection scheme meets a discrete energy stability. In addition, with the …

Socioeconomic Factors In The Diagnosis And Treatment Of Malignant Melanoma In Hispanic Vs. Non-Hispanic Patients: A National Cancer Database (Ncdb) Study, Julia Griffin, Sarah J. Aurit, Timothy Malouff, Peter Silberstein

Department of Statistics: Faculty Publications

Background: The incidence of melanoma is rapidly increasing in the United States. There is a paucity of research of how melanoma affects the Hispanic population, the quickest growing population.

Objective: To identify and understand how socioeconomic factors affect a Hispanic patients health outcome and treatment of malignant melanoma with comparisons to white, non-Hispanic (WNH) patients.

Methods: A retrospective study utilizing the National Cancer Database (NCDB) was completed investigating Hispanic patients (n=2282) and WNH patients (n=190,469) with Stage I-IV malignant melanoma. Outcome and socioeconomic variables were identified and compared across groups. Data was analyzed with SPSS and SAS …

Estimating The Prevalence Of Two Or More Diseases Using Outcomes From Multiplex Group Testing, Md S. Warasi, Joshua M. Tebbs, Christopher S. Mcmahan, Christopher R. Bilder

Department of Statistics: Faculty Publications

When screening a population for infectious diseases, pooling individual specimens (e.g., blood, swabs, urine, etc.) can provide enormous cost savings when compared to testing specimens individually. In the biostatistics literature, testing pools of specimens is commonly known as group testing or pooled testing. Although estimating a population-level prevalence with group testing data has received a large amount of attention, most of this work has focused on applications involving a single disease, such as human immunodeficiency virus. Modern methods of screening now involve testing pools and individuals for multiple diseases simultaneously through the use of multiplex assays. Hou et al. (2017, …

Penguins Go Parallel: A Grammar Of Graphics Framework For Generalized Parallel Coordinate Plots, Susan Vanderplas, Yawei Ge, Antony Unwin, Heike Hofmann

Department of Statistics: Faculty Publications

Parallel Coordinate Plots (PCP) are a valuable tool for exploratory data analysis of high-dimensional numerical data. The use of PCPs is limited when working with categorical variables or a mix of categorical and continuous variables. In this article, we propose Generalized Parallel Coordinate Plots (GPCP) to extend the ability of PCPs from just numeric variables to dealing seamlessly with a mix of categorical and numeric variables in a single plot. In this process we find that existing solutions for categorical values only, such as hammock plots or parsets become edge cases in the new framework. By focusing on individual observations …

Patient And Physician Factors Associated With First Diagnosis Of Non-Affective Psychotic Disorder In Primary Care, Joshua C. Wiener, Rebecca Rodrigues, Jennifer N S Reid, Suzanne Archie, Richard G Booth, Chiachen Cheng, Saadia Hameed Jan, Paul Kurdyak, Arlene G Macdougall, Lena Palaniyappan, Bridget L Ryan, Kelly K. Anderson

Epidemiology and Biostatistics Publications

Primary care physicians play a central role in pathways to care for first-episode psychosis, and their increased involvement in early detection could improve service-related outcomes. The aim of this study was to estimate the proportion of psychosis first diagnosed in primary care, and identify associated patient and physician factors. We used linked health administrative data to construct a retrospective cohort of people aged 14-35 years with a first diagnosis of non-affective psychosis in Ontario, Canada between 2005-2015. We restricted the sample to patients with help-seeking contacts for mental health reasons in primary care in the six months prior to first …

Institutional Design And Policy Responsiveness In Us States, Scott J. Lacombe

Government: Faculty Publications

There is significant disagreement on the moderating role of institutions on policy responsive- ness, yet overwhelmingly research in state politics has focused on single institutions. This project leverages a new aggregate scale of state institutions to evaluate if the collective insti- tutional context moderates the influence of public opinion on policy. I use a recently released latent scale of institutional context and find that high levels of accountability pressure strongly strengthen public opinion’s influence on policy for both economic and social policy, while the strength of a state’s checks and balance system is largely unrelated to policy responsiveness. These results …

Evaluating The Feasibility And Potential Impacts Of A Recovery-Oriented Psychosocial Rehabilitation Toolkit In A Health Care Setting In Kenya: A Mixed-Methods Study, Regina Casey, Joshua C. Wiener, Terry Krupa, Rosemary Lysaght, Marlene Janzen Le Ber, Ruth Ruhara, Elizabeth Price, Romaisa Pervez, Sean Kidd, Victoria Mutiso, David M Ndetei, Arlene G Macdougall

Epidemiology and Biostatistics Publications

OBJECTIVES: This pilot study evaluated the feasibility and potential impacts of delivering the Psychosocial Rehabilitation (PSR) Toolkit for people with serious mental illness within a health care setting in Kenya.

METHOD: This study used a convergent mixed-methods design. Participants were people with serious mental illness (n = 23), each with an accompanying family member, who were outpatients of a hospital or satellite clinic in semirural Kenya. The intervention consisted of 14 weekly group sessions of PSR cofacilitated by health care professionals and peers with mental illness. Quantitative data were collected from patients and family members using validated outcome measures before …

A Review On Derivative Hedging Using Reinforcement Learning, Peng Liu

Research Collection Lee Kong Chian School Of Business

Hedging is a common trading activity to manage the risk of engaging in transactions that involve derivatives such as options. Perfect and timely hedging, however, is an impossible task in the real market that characterizes discrete-time transactions with costs. Recent years have witnessed reinforcement learning (RL) in formulating optimal hedging strategies. Specifically, different RL algorithms have been applied to learn the optimal offsetting position based on market conditions, offering an automatic risk management solution that proposes optimal hedging strategies while catering to both market dynamics and restrictions. In this article, the author provides a comprehensive review of the use of …

Examining Failures Of Kc-135 Boom Assemblies Using Survival Analysis, Benjamin D. Miller

Theses and Dissertations

The purposes of this study are to confirm the applicability of survival analysis for predicting recurrent failures of a component of a military aircraft and to provide practical insights to maintenance managers and mission planners. The results of this study also can help the United States Department of Defense improve the CBM+ program. This study was able to predict recurrent failures of the component using Nelson-Aalen cumulative estimates. In addition, this study used a Cox proportional hazards regression model with shared frailty for measuring the effect of covariates on recurrent failures and unidentified heterogeneity in the model, which warranted future …

Probability Of Agreement As A Simulation Validation Methodology, Matthew C. Ledwith

Theses and Dissertations

Determining whether a simulation model is operationally valid requires the rigorous assessment of agreement between observed functional responses of the simulation model and the corresponding real world system or process of interest. This research seeks to extend and formulate the probability of agreement approach to the operational validation of simulation models. The first paper provides a methodological approach and an initial demonstration which leverages bootstrapping to overcome situations where one’s ability to collect real-world data is limited. The second paper extends the probability of agreement approach to account for second-order heteroscedastic variability structures and establishes a weighted probability of agreement …

Examining Fuel Service System Failures Of The Usaf R11 Using Survival Analysis, Roed M.S. Mejia

Theses and Dissertations

Recent events show that fuel supply is a large contributor to the success or failure of a military operation in response to a contingency. Any future near-peer conflict will stress the supply chain and require fully operational vehicles to be ready for the primary mission sets they support. In the United States Air Force (USAF), the readiness of fuel distribution trucks is crucial to meeting those mission sets in global operations. Utilizing non-parametric and semi-parametric survival models, which do not assume specific probability distributions, this study analyzes maintenance data for R-11 trucks that refuel aircraft.

Debris Survivability Study For Mega-Constellation Architectures, Joseph C. Canoy

Theses and Dissertations

The analysis for the overall theoretical debris survivabilty of mega-constellation architectures, with an emphasis on space-based ballistic missile defense constellation (SB-BMD), is explored via three extensive different Monte Carlo simulations: preliminary analysis of low Earth Orbit (LEO) mega-constellation survivabilty following a fragmentation event within the constellation, analysis of LEO mega-constellation survivability with a fragmentation event occurring on a satellite performing a maneuver to insert itself within the constellation, and the analysis of LEO mega-constellation survivabilty after a fragmentation event resulting from the destruction of a missile. The LEO mega-constellations represent the SB-BMD constellation. The first two analysis sections will include …

Viscoelastic Properties Of Human Facial Skin And Comparisons With Facial Prosthetic Elastomers, Mark W. Beatty, Alvin G. Wee, D. B. Marx, Lauren Ridgway, Bobby Simetich, Thiago Carvalho De Sousa, Kevin Vakilzadian, Joel Schulte

Department of Statistics: Faculty Publications

Prosthesis discomfort and a lack of skin-like quality is a source of patient dissatisfaction with facial prostheses. To engineer skin-like replacements, knowledge of the differences between facial skin properties and those for prosthetic materials is essential. This project measured six viscoelastic properties (percent laxity, stiffness, elastic deformation, creep, absorbed energy, and percent elasticity) at six facial locations with a suction device in a human adult population equally stratified for age, sex, and race. The same properties were measured for eight facial prosthetic elastomers currently available for clinical usage. The results showed that the prosthetic materials were 1.8 to 6.4 times …

Intellectual Disability Related To De Novo Germline Loss Of The Distal End Of The P-Arm Of Chromosome 17: A Case Report, Eden Pope, Matthew Huertas, Amar Paul, Braden Cunningham, Matthew Jennings, Ryan Perry, Stephanie Chavez, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

Hypothesis/Purpose: In this report we present a case of a 20-year-old female with congenital intellectual disability, stunted growth, and hypothyroidism. Competitive genetic hybridization (CHG) revealed a loss of 17p13.3, and the deletion was not present in either parent. This deletion has not previously been characterized, but mutations on the p-arm of chromosome 17 are responsible for Miller-Dieker Syndrome and Isolated Lissencephaly Sequence, both of which share symptoms in common with the patient.

Methods: Peripheral mononuclear cells (PBMCs) were used for karyotyping and competitive genetic hybridization (CHG). Bioinformatic analysis was carried out using the Genome Data Viewer (ncbi.nlm.nih.gov/genome/gdv).

Results: Karyotype was …

Investigating Respiratory Simplification Caused By Prenatal Rage Upregulation, Paul Reynolds

Annual Research Symposium

No abstract provided.

Potential Role For Rage In The Development Of Secondhand Smoke-Induced Chronic Sinusitis, Paul Reynolds

Annual Research Symposium

No abstract provided.

Rage Inhibition Reduces Timp And Decreases Cell Invasion In Cigarette Smoke Extract (Cse) Treated Oral Squamous Carcinoma Cells, Paul Reynolds

Annual Research Symposium

No abstract provided.

Inflammatory Cytokine Elaboration Following Secondhand Smoke Exposure Is Mediated In Part By Rage Signaling, Paul Reynolds

Annual Research Symposium

No abstract provided.

Rage Availability Lessens The Degree Of Dysfunctional Mitochondrial Bioenergetics Following Chronic Secondhand Smoke Exposure, Paul Reynolds

Annual Research Symposium

No abstract provided.

Gestational Dependent Responses To Second Hand Smoke (Shs) In Mouse Pregnancies, Paul Reynolds

Annual Research Symposium

No abstract provided.

Reversible Emerging Neuropsychological Pattern In Chronic Intractable Migraine, Tanner Williford, Pooja Chemiti, Mason Allen, Brandon Burrell, Stephanie Chavez, Jude Emego, Bridger Gunter, Matthew Huertas, Matthew Jennings, Roshni Jogin, Paulo Kelly, Laura Minor, Steven Salazar, Jameson Williams, David W. Sant, John A. Kriak, Kyle B. Bills

Annual Research Symposium

No abstract provided.

The Science Of Oral Carbapenems, Landon Olsen, Daniel J. Yang, Aiyi Chen, Thahn-Liem Vu, H. Stephen Lee

Annual Research Symposium

No abstract provided.

The Immunomodulating Effects Of Morphine Dependence And Withdrawal In Rat Lung, Liver, Spleen And Blood, Yensi Munoz

Annual Research Symposium

No abstract provided.

The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor

Annual Research Symposium

It is well documented that barriers exist for underrepresented minorities to enter the field of medicine and even more competitive residencies. As defined by the NRMP, competitive specialties include but are not limited to Interventional Radiology, Orthopedic Surgery, Plastic Surgery, Radiation Oncology, Vascular Surgery, Neurosurgery, Dermatology, and Otornylogy (NRMP-AMA). A large number of osteopathic medical school graduates have a history of going into primary care specialties because many osteopathic medical schools have a primary care focus (Primary Care- Osteopathic Medicine). The emphasis on primary care, whether intentional or not, can foster a less-than-advantageous environment for underrepresented minority students (URM), pursuing …

Appearance Of Two Distinct Clusters Of Glucose Dysregulation In Chronic Intractable Migraine, Roshni Jogin, Kaitlyn Mcfarland, Aparna Naik, Tanner Williford, Matthew Conway, Amar Paul, John A. Kriak, David W. Sant, Kyle B. Bills

Annual Research Symposium

No abstract provided.

Heterodyned Whole-Body Vibration Ameliorates Anxiety In Opioid-Use Disorder, Kailee Edwards, Braden Cunningham, Alfred Amendolara, Marryam Anwar, Jon Gonzales, Roshni Jogin, Wyatt Magoffin, Amar Paul, Ryan Perry, James Pike, Nathan Swallow, Steven Tung, Mary Seamons, Andrew Payne, John A. Kriak, David W. Sant, David W. Sant

Annual Research Symposium

No abstract provided.

Planning A Review Of The Pathogenesis And Management Of Valley Fever, Seattle Shakur

Annual Research Symposium

No abstract provided.

Clinical Trial Subject Recruitment: Research Immersion Experience, Brooklyn Janes

Annual Research Symposium

No abstract provided.

Serdexmethylphenidate/Dexmethylphenidate – A Promising Treatment Option For Childhood Attention Deficit Hyperactivity Disorder (Adhd), N Troy To, H Stephen Lee

Annual Research Symposium

To review the phase 2 and phase 3 clinical trials of Serdexmethylphenidate and dexmethylphenidate (SDX/d-MPH) in the treatment of Attention Deficit/Hyperactivity disorder (ADHD) in children.