Physical Sciences and Mathematics Commons^™

Measuring The Performance Of Sdgs In Provincial Level Using Regional Sustainable Development Index, Nurafiza Thamrin, Ika Yuni Wulansari, Puguh Bodro Irawan

Journal of Environmental Science and Sustainable Development

Measuring the national and sub-national progress in achieving such globally adopted development agendas as Sustainable Development Goals (SDGs) is particularly challenging due to data availability and compatibility of indicators to measure SDGs, especially in Indonesia. This paper attempts to measure the performance of sustainable development at the regional level in Indonesia by newly constructing a multidimensional composite index called the Regional Sustainable Development Index (RSDI). RSDI comprises four dimensions, covering comprehensive economic, social, environmental, and governance indicators. By applying factor analysis, the paper assesses the uncertainty of RSDI and the sensitivity of its composing indicators, then further investigates the relationship …

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …

Cabozantinib Plus Atezolizumab In Previously Untreated Advanced Hepatocellular Carcinoma And Previously Treated Gastric Cancer And Gastroesophageal Junction Adenocarcinoma: Results From Two Expansion Cohorts Of A Multicentre, Open-Label, Phase 1b Trial (Cosmic-021)., Daneng Li, Yohann Loriot, Adam Burgoyne, James Cleary, Armando Santoro, Daniel Lin, Santiago Ponce Aix, Ignacio Garrido-Laguna, Ramu Sudhagoni, Xiang Guo, Svetlana Andrianova, Scott Paulson

Kimmel Cancer Center Faculty Papers

BACKGROUND: Cabozantinib is approved for previously treated advanced hepatocellular carcinoma (aHCC) and has been investigated in gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJ). Atezolizumab plus bevacizumab is approved for unresectable or metastatic HCC untreated with prior systemic therapy. We evaluated efficacy and safety of cabozantinib plus atezolizumab in aHCC previously untreated with systemic anticancer therapy or previously treated GC/GEJ.

METHODS: COSMIC-021 (ClinicalTrials.gov, NCT03170960) is an open-label, phase 1b study in solid tumours with a dose-escalation stage followed by tumour-specific expansion cohorts, including aHCC (cohort 14) and GC/GEJ (cohort 15). Eligible patients were aged ≥18 years with measurable locally advanced, …

Prt543, A Protein Arginine Methyltransferase 5 Inhibitor, In Patients With Advanced Adenoid Cystic Carcinoma: An Open-Label, Phase I Dose-Expansion Study, Renata Ferrarotto, Paul Swiecicki, Dan Zandberg, Robert Baiocchi, Robert Wesolowski, Cristina Rodriguez, Meredith Mckean, Hyunseok Kang, Varun Monga, Rajneesh Nath, Neil Palmisiano, Naveen Babbar, William Sun, Glenn Hanna

Department of Medical Oncology Faculty Papers

OBJECTIVES: Currently, no systemic treatments are approved for patients with recurrent and/or metastatic (R/M) adenoid cystic carcinoma (ACC). PRT543, a protein arginine methyltransferase 5 inhibitor that downregulates NOTCH1 and MYB signalling in tumours, is a potential candidate for R/M ACC treatment. We report the safety, tolerability and preliminary efficacy of PRT543 in a dose-expansion cohort of patients with R/M ACC.

MATERIALS AND METHODS: This phase I multicentre, open-label, sequential-cohort, dose-escalation and dose-expansion study (NCT03886831) enrolled patients with advanced solid tumours and select haematologic malignancies. Dose-escalation study design and results were reported previously. In the dose expansion, patients with R/M ACC …

Atmospheric 14Co2 Observation: A Novel Method To Evaluate Carbon Emissions, Zhenchuan Niu, Peng Wang, Shugang Wu, Weijian Zhou

Bulletin of Chinese Academy of Sciences (Chinese Version)

As an important carbon emitter, China faces the stress of carbon peaking and carbon neutrality goals and international carbon reduction duty. The accurate data of carbon emissions are important to evaluate the carbon peaking and carbon neutrality goals and fulfill the international duty of carbon reduction. The Intergovernmental Panel on Climate Change (IPCC) report recommends the combination of top-down atmospheric CO₂ observation with atmospheric inversion to verify the bottom-up inventory of carbon emissions, and the atmospheric ¹⁴CO₂ observation can make the verification more accurate. Radiocarbon (14C) is the most precise tracer of fossil fuel CO₂ and …

Challenges And Countermeasures For Treatment And Remediation Of Contaminated Mega-Sites In China, Xiaoyong Liao, Yixuan Hou, You Li, Tianyi Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The treatment and remediation of pollution at contaminated mega-sites poses a significant challenge in the environmental science both domestically and internationally. Contaminated mega-sites are characterized by their widespread impact, multiple types of pollutants, and significant ecological and environmental threats. The environmental behavior cognition and efficient remediation at contaminated mega-sites face enormous challenges, among which key technological issues such as the formation mechanism of soil and groundwater pollution, accurate identification of pollution sources, and intelligent decision-making optimization urgently need to be solved. In China, contaminated mega-sites are concentrated in economically developed regions such as Beijing-Tianjin-Hebei, the Yangtze River Economic Belt, and …

Spatial Agglomeration And Environmental Effects Of Heavy Polluting Industries In China: Characteristics And Enlightenment, Hongyang Chen, Jianhui Yu, Wenzhong Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Heavy polluting industries are the important sources of industrial pollutant. Understanding the spatial agglomeration characteristics, influencing factors, agglomeration mechanism and environmental effects of China’s heavy polluting industries can help identify potential pollution risk areas to cope with increasingly severe environmental pollution problems. Based on the industrial economic data from 1999 to 2021, the spatial distribution and agglomeration characteristics of heavy polluting industries are characterized. It is found that: (1) Shandong, Jiangsu, Zhejiang, and Guangdong are the regions with high output value of the development of heavy polluting industries in the past 20 years, while Xinjiang, Inner Mongolia, Shanxi, Shaanxi, Henan, …

Stereotactic Mr-Guided On-Table Adaptive Radiation Therapy (Smart) For Borderline Resectable And Locally Advanced Pancreatic Cancer: A Multi-Center, Open-Label Phase 2 Study, Michael Chuong, Percy Lee, Daniel Low, Joshua Kim, Kathryn Mittauer, Michael Bassetti, Carri Glide-Hurst, Ann Raldow, Yingli Yang, Lorraine Portelance, Kyle Padgett, Bassem Zaki, Rongxiao Zhang, Hyun Kim, Lauren Henke, Alex Price, Joseph Mancias, Christopher Williams, John Ng, Ryan Pennell, M Raphael Pfeffer, Daphne Levin, Adam Mueller, Karen Mooney, Patrick Kelly, Amish Shah, Luca Boldrini, Lorenzo Placidi, Martin Fuss, Parag Jitendra Parikh

Department of Radiation Oncology Faculty Papers

BACKGROUND AND PURPOSE: Radiation dose escalation may improve local control (LC) and overall survival (OS) in select pancreatic ductal adenocarcinoma (PDAC) patients. We prospectively evaluated the safety and efficacy of ablative stereotactic magnetic resonance (MR)-guided adaptive radiation therapy (SMART) for borderline resectable (BRPC) and locally advanced pancreas cancer (LAPC). The primary endpoint of acute grade ≥ 3 gastrointestinal (GI) toxicity definitely related to SMART was previously published with median follow-up (FU) 8.8 months from SMART. We now present more mature outcomes including OS and late toxicity.

MATERIALS AND METHODS: This prospective, multi-center, single-arm open-label phase 2 trial (NCT03621644) enrolled 136 …

Interpretable Word-Level Sentiment Analysis With Attention-Based Multiple Instance Classification Models, Chenyu Yang

Statistical Science Theses and Dissertations

In this study, our main objective is to tackle the black-box nature of popular machine learning models in sentiment analysis and enhance model interpretability. We aim to gain more insight into the decision-making process of sentiment analysis models, which is often obscure in those complex models. To achieve this goal, we introduce two word-level sentiment analysis models.

The first model is called the attention-based multiple instance classification (AMIC) model. It combines the transparent model structure of multiple instance classification and the self-attention mechanism in deep learning to incorporate the contextual information from documents. As demonstrated by a wine review dataset …

Microplate-Like Metal Pyrophosphate Engineered On Ni-Foam Towards Multifunctional Electrode Material For Energy Conversion And Storage, Rishabh Srivastava

Electronic Theses & Dissertations

High clean energy demand, dire need for sustainable development, and low carbon footprints are the few intuitive challenges, leading researchers to aim for research and development for high-performance energy devices. The development of materials used in energy devices is currently focused on enhancing the performance, electronic properties, and durability of devices. Tunning the attributes of transition metals using pyrophosphate (P₂O₇) ligand moieties can be a promising approach to meet the requirements of energy devices such as water electrolyzers and supercapacitors, although such a material’s configuration is rarely exposed for this purpose of study.

Herein, we grow …

Test Event Example 12/14/23, Metzalli Demolastname

Annual Research Symposium

No abstract provided.

Ohio Recovery Housing: Resident Risk And Outcomes Assessment, Elyjiah Potter, Bivin Sadler

SMU Data Science Review

Addiction and substance abuse disorder is a significant problem in the United States. Over the past two decades, the United States has faced a boom in substance abuse, which has resulted in an increase in death and disruption of families across the nation. The State of Ohio has been particularly hard hit by the crisis, with overdose rates nearly doubling the national average. Established in the mid 1970’s Sober Living Housing is an alcohol and substance use recovery model emphasizing personal responsibility, sober living, and community support. This model has been adopted by the Ohio Recovery Housing organization, which seeks …

Differentiation Of Human, Dog, And Cat Hair Fibers Using Dart Tofms And Machine Learning, Laura Ahumada, Erin R. Mcclure-Price, Chad Kwong, Edgard O. Espinoza, John Santerre

SMU Data Science Review

Hair is found in over 90% of crime scenes and has long been analyzed as trace evidence. However, recent reviews of traditional hair fiber analysis techniques, primarily morphological examination, have cast doubt on its reliability. To address these concerns, this study employed machine learning algorithms, specifically Linear Discriminant Analysis (LDA) and Random Forest, on Direct Analysis in Real Time time-of-flight mass spectra collected from human, cat, and dog hair samples. The objective was to develop a chemistry- and statistics-based classification method for unbiased taxonomic identification of hair. The results of the study showed that LDA and Random Forest were highly …

The Dose-Response Effect Of Aerobic Exercise On Inflammation In Colon Cancer Survivors, Justin C. Brown, Stephanie L.E. Compton, Jeffrey A. Meyerhardt, Guillaume Spielmann, Shengping Yang

School of Medicine Faculty Publications

Background; Physical activity after surgical resection for colon cancer is associated with significantly longer disease-free survival. Inflammation is hypothesized to mediate the association between physical activity and disease-free survival in colon cancer. Methods; In this exploratory analysis of a randomized dose-response trial, 39 colon cancer survivors who completed standard therapy were stratified by cancer stage and randomized in a 1;1;1 ratio to one of three treatment groups for 24 weeks of usual-care control, 150 min/wk of moderate-intensity aerobic exercise (low-dose), or 300 min/wk of moderate-intensity aerobic exercise (high-dose). Inflammation outcomes included high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL6), and soluble tumor …

Investigating The Effects Of A Southward Flow In The Southeastern Florida Shelf Using Robotic Instruments, Alfredo Quezada

All HCAS Student Capstones, Theses, and Dissertations

We deployed a Slocum G3 glider fitted with an acoustic Doppler current profiler (ADCP), a Conductivity-Temperature-Depth sensor (CTD), optics sensor channels, and a propeller on the Southeastern Florida shelf. The ADCP and CTD provide continuous measurements of Northern and Eastern current velocity components, salinity, temperature, and density, throughout the water column in a high-current environment. The optics sensor channels are able to provide measurements of chlorophyll concentrations, colored dissolved organic matter (CDOM), and backscatter particle counts. Additionally, for one of the glider deployments, we deployed a Wirewalker wave-powered profiling platform system also fitted with an ADCP and a CTD in …

Climate Change Impact On Bridge Scour Risk In Ny State: A Gis-Based Risk Analysis Model, Muhammad Hassan Butt

Publications and Research

Bridge scour, the primary cause of bridge failure in the United States, escalates post-severe storms, necessitating effective mitigation. This study employs a GIS-based risk analysis model to assess climate change's impact on bridge scour and associated risks in New York State. Data from the National Bridge Inventory, climate hazard maps, and geospatial data are integrated.

Development Of An App For The Kalamazoo Nature Center, Ernest Au

Honors Theses

Kalamazoo Nature Center (KNC), which has been recognized by its peers as one of the top nature centers in the country, is home to over 14 miles of hiking trails winding through woods, wetlands, and prairies. There are numerous places/plots in KNC that have an interesting and impressive history besides being home to a variety of animals and hundreds of wildflowers and other plant life. To improve the visitor’s experience at KNC, we will design a software app via the senior capstone project at the department of Computer Science at WMU. As the first step towards establishing a reference model …

Teaching Reproducibility To First Year College Students: Reflections From An Introductory Data Science Course, Brennan L. Bean

Journal on Empowering Teaching Excellence

Access the online Pressbooks version of this article here.

Modern technology threatens traditional modes of classroom assessment by providing students with automated ways to write essays and take exams. At the same time, modern technology continues to expand the accessibility of computational tools that promise to increase the potential scope and quality of class projects. This paper presents a case study where students are asked to complete a “reproducible” final project in an introductory data science course using the R programming language. A reproducible project is one where an instructor can easily regenerate the results and conclusions from the submitted …

Analyzing The Efficacy Of Covid-19 Travel Bans: A Regression Analysis Approach, Mallory Kochanek

Honors Projects

Some might associate the term ‘public health’ with the pandemic that occurred in 2020. COVID-19 spread like most have never seen in their lifetime. It is useful to look at the effectiveness of the travel re- strictions in mitigating the spread of the global pandemic. Using linear regression and network regression, we obtain parameter estimates to determine the relation of predictors, such as network effect, percentage of urban population and GDP, on the COVID-19 incidence rate for the months January to April of 2020. Linear regression does not ac- count for the correlation structure of the data. Network regression, on …

Is The Declining Birthrate Really An Issue For The Economy?, Harsh Ramesh Pednekar, Theodore Lee, Darrion Chin

Introduction to Research Methods RSCH 202

This study aims to explore the complex implications of declining birth rates on the economy, focusing on GDP per capita as a crucial metric, and aims to uncover both potential opportunities and challenges stemming from this demographic transformation using regression analysis. Using a quantitative methodology and secondary data from OECD.stat, World Population Review, and World Bank, the study explores the relationship between declining birth rates and economic impacts. GDP per capita serves as an essential dependent variable, and it accounts for control variables such as labour force participation, literacy, and education levels, child dependence ratio, and physical capital. Past studies …

Random Variable Spaces: Mathematical Properties And An Extension To Programming Computable Functions, Mohammed Kurd-Misto

Computational and Data Sciences (PhD) Dissertations

This dissertation aims to extend the boundaries of Programming Computable Functions (PCF) by introducing a novel collection of categories referred to as Random Variable Spaces. Originating as a generalization of Quasi-Borel Spaces, Random Variable Spaces are rigorously defined as categories where objects are sets paired with a collection of random variables from an underlying measurable space. These spaces offer a theoretical foundation for extending PCF to natively handle stochastic elements.

The dissertation is structured into seven chapters that provide a multi-disciplinary background, from PCF and Measure Theory to Category Theory with special attention to Monads and the Giry Monad. The …

Static And Dynamic State Estimation Applications In Power Systems Protection And Control Engineering, Ibukunoluwa Olayemi Korede

Doctoral Dissertations

The developed methodologies are proposed to serve as support for control centers and fault analysis engineers. These approaches provide a dependable and effective means of pinpointing and resolving faults, which ultimately enhances power grid reliability. The algorithm uses the Least Absolute Value (LAV) method to estimate the augmented states of the PCB, enabling supervisory monitoring of the system. In addition, the application of statistical analysis based on projection statistics of the system Jacobian as a virtual sensor to detect faults on transmission lines. This approach is particularly valuable for detecting anomalies in transmission line data, such as bad data or …

Integrating Machine Learning Methods For Medical Diagnosis, Jazmin Quezada

Open Access Theses & Dissertations

Abstract:The rapid advancement of machine learning techniques has revolutionized the field of medical diagnosis by offering powerful tools to analyze complex data sets and make accurate predictions. In this proposed method, we present a novel approach that integrates machine learning and optimization models to enhance the accuracy of medical diagnoses. Our method focuses on fine-tuning and optimizing the parameters of machine learning algorithms commonly used in medical diagnosis, such as logistic regression, support vector machines, and neural networks. By employing optimization techniques, we systematically explore the parameter space of these algorithms to discover the most optimal configurations. Moreover, by representing …

The Impact Of Neighborhood Socioeconomic Disadvantage On Operative Outcomes After Single-Level Lumbar Fusion, Grace Y. Ng, Ritesh Karsalia, Ryan S. Gallagher, Austin J. Borja, Jianbo Na, Scott Mcclintock, Neil R. Malhotra

Mathematics Faculty Publications

INTRODUCTION: The relationship between socioeconomic status and neurosurgical outcomes has been investigated with respect to insurance status or median household income, but few studies have considered more comprehensive measures of socioeconomic status. This study examines the relationship between Area Deprivation Index (ADI), a comprehensive measure of neighborhood socioeconomic disadvantage, and short-term postoperative outcomes after lumbar fusion surgery. METHODS: 1861 adult patients undergoing single-level, posterior-only lumbar fusion at a single, multihospital academic medical center were retrospectively enrolled. An ADI matching protocol was used to identify each patient's 9-digit zip code and the zip code-associated ADI data. Primary outcomes included 30- and …

Wavelet Compression As An Observational Operator In Data Assimilation Systems For Sea Surface Temperature, Bradley J. Sciacca

University of New Orleans Theses and Dissertations

The ocean remains severely under-observed, in part due to its sheer size. Containing nearly billion of water with most of the subsurface being invisible because water is extremely difficult to penetrate using electromagnetic radiation, as is typically used by satellite measuring instruments. For this reason, most observations of the ocean have very low spatial-temporal coverage to get a broad capture of the ocean’s features. However, recent “dense but patchy” data have increased the availability of high-resolution – low spatial coverage observations. These novel data sets have motivated research into multi-scale data assimilation methods. Here, we demonstrate a new assimilation approach …

Models Of Shared Care For The Management Of Psychotic Disorder After First Diagnosis In Ontario., Joshua C. Wiener, Rebecca Rodrigues, Jennifer N S Reid, Kelly K. Anderson

Epidemiology and Biostatistics Publications

OBJECTIVE: To describe the provision of care for young people following first diagnosis of psychotic disorder.

DESIGN: Retrospective cohort study using health administrative data.

SETTING: Ontario.

PARTICIPANTS: People aged 14 to 35 years with a first diagnosis of nonaffective psychotic disorder in Ontario between 2005 and 2015 (N=39,449).

MAIN OUTCOME MEASURES: Models of care, defined by psychosis-related service contacts with primary care physicians and psychiatrists during the 2 years after first diagnosis of psychotic disorder.

RESULTS: During the 2-year follow-up period, 29% of the cohort received only primary care, 30% received only psychiatric care, and 32% received both primary and …

Bayesian Strategies For Propensity Score Estimation In Causal Inference., Uthpala I. Wanigasekara

Electronic Theses and Dissertations

Causal inference is a method used in various fields to draw causal conclusions based on data. It involves using assumptions, study designs, and estimation strategies to minimize the impact of confounding variables. Propensity scores are used to estimate outcome effects, through matching methods, stratification, weighting methods, and the Covariate Balancing Propensity Score method. However, they can be sensitive to estimation techniques and can lead to unstable findings. Researchers have proposed integrating weighing with regression adjustment in parametric models to improve causal inference validity. The first project focuses on Bayesian joint and two-stage methods for propensity score analysis. Propensity score modeling …

Analyses Of Effect Indices Across Single-Case Research Designs In Counseling, Cian L. Brown

Graduate Theses and Dissertations

Single case research design (SCRD) is a common methodology used across clinical disciplines to determine treatments effectiveness by comparing treatment conditions to baseline conditions in individual cases, usually among researchers working with smaller samples. Although popular within behavioral disciplines such as special education and behavioral analysis, studies have begun to emerge in counseling. However, guidance and current understanding of the use of SCRD in counseling is limited. A content analysis of counseling journals from 2003 to 2014 yielded only 7 studies using SCRD. In 2015, the flagship counseling journal, Journal of Counseling and Development, published a special issue on the …

Foundations Of Memory Capacity In Models Of Neural Cognition, Chandradeep Chowdhury

Master's Theses

A central problem in neuroscience is to understand how memories are formed as a result of the activities of neurons. Valiant’s neuroidal model attempted to address this question by modeling the brain as a random graph and memories as subgraphs within that graph. However the question of memory capacity within that model has not been explored: how many memories can the brain hold? Valiant introduced the concept of interference between memories as the defining factor for capacity; excessive interference signals the model has reached capacity. Since then, exploration of capacity has been limited, but recent investigations have delved into the …

Radiation Exposure Calibration Of The Al2o3:C With Radium-226 And Cesium-137 Using The Osl Method, Selma Tepeli Aydin

All Theses

Optically stimulated luminescence (OSL) dosimetry was utilized to calibrate Al₂O₃:C powder dosimeters, available commercially as the nanoDot® from Landauer Inc., and compare the dosimeter response to radium-226 (²²⁶Ra) and cesium-137 (¹³⁷Cs). The signal from the OSL was quantified using a microSTARii^® OSL reader also produced by Landauer Inc. Dose-response curves were developed for ²²⁶Ra and ¹³⁷Cs experiments (5 dosimeters each) at thirteen absorbed doses. Individual dosimeter response was tracked by serial number. Linear regression analysis was performed to determine if there were significant differences between the intercepts of the …