Physical Sciences and Mathematics Commons^™

The Development Of Signal Transduction Pathways During Epididymal Maturation Is Calcium Dependent, Heath W. Ecroyd, Kelly Asquith, Russell C. Jones, Robert J. Aitken

Heath Ecroyd

Capacitation has been correlated with the activation of a cAMP-PKA-dependent signaling pathway leading to protein tyrosine phosphorylation. The ability to exhibit this response to cAMP matures during epididymal maturation in concert with the ability of the sperrnatozoa to capacitate. In this study, we have addressed the mechanisms by which spermatozoa gain the potential to activate this signaling pathway during epididymal maturation. In a modified Tyrode's medium containing 1.7 mM calcium, caput spermatozoa had significantly higher [Ca2+](i) than caudal cells and could not tyrosine phosphorylate in response to cAMP. However, in calcium-depleted medium both caput and caudal cells could exhibit a …

The Interaction Of Alphab-Crystallin With Mature Alpha-Synuclein Amyloid Fibrils Inhibits Their Elongation, Christopher A. Waudby, Tuomas P. J Knowles, Glyn L. Devlin, Jeremy N. Skepper, Heath Ecroyd, John A. Carver, Mark E. Welland, John Christodoulou, Christopher M. Dobson, Sarah Meehan

Heath Ecroyd

alphaB-Crystallin is a small heat-shock protein (sHsp) that is colocalized with alpha-synuclein (alphaSyn) in Lewy bodies—the pathological hallmarks of Parkinson's disease—and is an inhibitor of alphaSyn amyloid fibril formation in an ATP-independent manner in vitro. We have investigated the mechanism underlying the inhibitory action of sHsps, and here we establish, by means of a variety of biophysical techniques including immunogold labeling and nuclear magnetic resonance spectroscopy, that alphaB-crystallin interacts with alphaSyn, binding along the length of mature amyloid fibrils. By measurement of seeded fibril elongation kinetics, both in solution and on a surface using a quartz crystal microbalance, this binding …

Investigating The Impact Of Restricted Irrigation Practices On Soil Moisture Variability And Distribution In A Dry Farmed Vineyard Site, Boise, Idaho, J. Duffin, David Wilkins, J. Guenther

David E. Wilkins

Changing climate in semiarid regions may result in increased water stresses for agricultural production as timing and form of precipitation may result in diminished surface water for irrigation. To prepare for these changing conditions, studies are being conducted on the possibility of dry farmed agriculture as an alternative to irrigated production. This study specifically investigates the ability to grow productive wine grapes with limited or zero irrigation in the Boise Front Foothills, West Foothills TIC Vineyard, located in a climate zone receiving less than 300 mm of annual precipitation. Traditional vineyard performance factors such as planting densities, soil type, rootstock, …

Sophomore Field Experiences As An Introduction To The Nature Of Geosciences: Data Collection And Analysis Using Dendrochronology, David Wilkins, M. Kunkel

David E. Wilkins

Opportunities for field experiences are often presented as a primary reason that undergraduate students gravitate towards geosciences as a major field of study. What those students may not understand is that, for professional geoscientists, field experiences go beyond the freshman-level field trip, and students may overlook the processes of observation, data collection and analysis that are inherent to the science. The Department of Geosciences at Boise State has developed a set of sophomore field experience courses designed to "set the hook" into new majors and prepare them for field experiences in upper division coursework. These sophomore courses have been shown …

Erasing Boundaries: Global Resource Sharing In The 21st Century, Robert A. Seal

Robert A Seal

Academic libraries have long been accustomed to participating in cooperative ventures with neighboring institutions as well as with those in other regions of their country. In large part, such activities have grown out of a desire to reduce or control costs, as well as to provide users with a broader base of materials for research, study, and teaching. Because not even a well-developed national library is able to fulfill all its users' needs all the time, today's university libraries must depend upon one another to fulfill those needs. For many decades, the resource sharing tradition has been particularly strong among …

Wiki Leaks Revelations In Global Context—The War Between ‘Right To Publish’ And ‘Ethical Code Of Conduct, Ratnesh Dwivedi Mr

Ratnesh Dwivedi

WikiLeaks is an international non-profit organisation that publishes submissions of private, secret, and classified media from anonymous news sources, news leaks, and whistleblowers. Its website, launched in 2006 under The Sunshine Press organisation claimed a database of more than 1.2 million documents within a year of its launch. WikiLeaks describes its founders as a mix of Chinese dissidents, journalists, mathematicians, and start-up company technologists from the United States, Taiwan, Europe, Australia, and South Africa. Julian Assange, an Australian Internet activist, is generally described as its director. The site was originally launched as a user-editable wiki, but has progressively moved towards …

Using Social Media To Build Community Disaster Resilience (Powerpoint), Neil Dufty

Neil Dufty

No abstract provided.

Examination Of The Total Flood Warning System In Victoria (Report), Neil Dufty

Neil Dufty

No abstract provided.

A Critical Study Of Organizational Communication And Organizational Communication Theories- A Historical Perspective, Ratnesh Dwivedi Mr

Ratnesh Dwivedi

Organizational Communication is the study that looks at human communication within and outside the organization. Conrad and Poole (1998) break the definition of organizational communication in parts, by first defining communication and then analyses the organization. These researchers define communication as “a process through which people, acting together, create, sustain, and manage meanings through the use of verbal and nonverbal signs and symbols within a particular context” (Conrad and Poole, 1998, p. 5). In the context of this book, Kenyans and their leaders are communicating their views and final decision through the ballot box to elect their third president, during …

A Multi-Platform Application Suite For Enhancing South Asian Language Pedagogy, Tao Bai, Christopher K. Chung, Konstantin Läufer, Daisy Rockwell, George K. Thiruvathukal

George K. Thiruvathukal

This interdisciplinary project explores the potential for handheld/wireless (H/W) technology in the context of language education within and beyond the classroom. Specifically, we have designed and implemented a suite of multi-platform (desktop/laptop, handheld, and browser) applications to enhance the teaching of South Asian languages such as Hindi-Urdu. Such languages are very difficult to learn, let alone write, and H/W devices (with their handwriting/drawing capabilities) can play a significant role in overcoming the learning curve. The initial application suite includes a character/word tracer, a word splitter/joiner, a smart flashcard with audio, contextual augmented stories for reading comprehension, and a poetic metronome. …

Public Accountability And Media : Its Success And Failure In Performing The Role As A Force For Public Accountability, Ratnesh Dwivedi Mr

Ratnesh Dwivedi

Media accountability is a phrase that refers to the general (especially western) belief that mass media has to be accountable in the public’s interest - that is, they are expected to behave in certain ways that contribute to the public good. The concept is not clearly defined, and often collides with commercial interests of media owners; legal issues, such as the constitutional right to the freedom of the press in the U.S.; and governmental concerns about public security and order. Several international organizations, like International Freedom of Expression Exchange, Freedom House, International Press Institute, World Press Freedom Committee and the …

Mining Interesting Link Formation Rules In Social Networks, Cane Wing-Ki Leung, Ee Peng Lim, David Lo, Jianshu Weng

David LO

Link structures are important patterns one looks out for when modeling and analyzing social networks. In this paper, we propose the task of mining interesting Link Formation rules (LF-rules) containing link structures known as Link Formation patterns (LF-patterns). LF-patterns capture various dyadic and/or triadic structures among groups of nodes, while LF-rules capture the formation of a new link from a focal node to another node as a postcondition of existing connections between the two nodes. We devise a novel LF-rule mining algorithm, known as LFR-Miner, based on frequent subgraph mining for our task. In addition to using a support-confidence framework …

Identification Of Abundant Alkyl Ether Glycerophospholipids In The Human Lens By Tandem Mass Spectrometry Techniques, Roger J. Truscott, Jane Deeley, Todd W. Mitchell, Michael Thomas, Stephen J. Blanksby

Stephen Blanksby

Previous studies have shown that the human lens contains glycerophospholipids with ether linkages. These lipids differ from conventional glycerophospholipids in that the sn-1 substituent is attached to the glycerol backbone via an 1-O-alkyl or an 1-O-alk-1'-enyl ether rather than an ester bond. The present investigation employed a combination of collision-induced dissociation (CID) and ozone-induced dissociation (OzID) to unambiguously distinguish such 1-O-alkyl and 1-O-alk-1'-enyl ethers. Using these methodologies the human lens was found to contain several abundant 1-O-alkyl glycerophos-phoethanolamines, including GPEtn(16:0e/9Z-18:1), GPEtn(11Z-18:1e/9Z-18:1), and GPEtn(18:0e/9Z-18:1), as well as a related series of unusual 1-O-alkyl glycerophosphoserines, including GPSer(16:0e/9Z-18:1), GPSer(11Z-18:1e/9Z-18:1), GPSer(18:0e/9Z-18:1) that to our …

Detection And Quantification Of Tear Phospholipids And Cholesterol In Contact Lens Deposits: The Effect Of Contact Lens Material And Lens Care Solution, Jennifer Saville, Zhenjun Zhao, Mark D.P. Willcox, Stephen J. Blanksby, Todd W. Mitchell

Stephen Blanksby

PURPOSE. To examine the deposition of tear phospholipids and cholesterol onto worn contact lenses and the effect of lens material and lens care solution. METHODS. Lipids were extracted from tears and worn contact lenses using 2: 1 chloroform: methanol and the extract washed with aqueous ammonium acetate, before analysis by electrospray ionization tandem mass spectrometry (ESI-MS/MS). RESULTS. Twenty-three molecular lipids from the sphingomyelin (SM) and phosphatidylcholine (PC) classes were detected in tears, with total concentrations of each class determined to be 5 +/- 1 pmol/mu L (similar to 3.8 mu g/mL) and 6 +/- 1 pmol/mu L (similar to 4.6 …

Towards Novel Entangled Carbon Nanotube Composite Electrodes, Gordon G. Wallace, P. Sherrell, J. Chen, A. Minett

Gordon Wallace

The commercialization of carbon nanotube electrodes is impeded by the lack of bulk processing techniques. One approach to overcome this impediment is the growth of macroscopic CNT composite architectures which do not require any extra processing. Unfortunately the fundamental growth mechanisms of these carbon composites is not currently understood. To probe this mechanism a systematic examination of the effect of certain growth parameters was undertaken. Within this paper we present the promising preliminary findings of this study revealing extremely complex relationships between variables during growth. We also present the performance of the produced architectures as capacitor electrodes and the further …

When Practice Doesn’T Make Perfect: Effects Of Task Goals On Learning Computing Concepts, Craig S. Miller, Amber Settle

Amber Settle

Engaging Game Design Students Using Peer Evaluation, Amber Settle, Charles Wilcox, Chad Settle

Amber Settle

Computational Thinking In A Game Design Course, Amber Settle

Amber Settle

Journeys Between Nature And Culture, Diana Wood Conroy, Lesley Head, Jennifer Lamb

Diana Wood Conroy

No abstract provided.

Issues In Human Capital Development : Lessons For Public Administration And Governance, Deogratias Harorimana Mr

Dr Deogratias Harorimana

With few minerals or other natural resources, Rwanda believes that she can still achieve her ambitions by investing in human capital - her unique resource. If this ambition can be achieved, then is this the next role model for international development? We used a case study design and analysis methods to examine development models used elsewhere in recent decades, using both qualitative and quantitative data on Rwanda to establish the comparative advantages in relation to Singapore’s economic development model. The implications for international development are that (1) an effective human capital development strategy should be inclusive enough to respond to …

Professional Development For Graduate Students Through Outreach Partnerships With Science Learning Centers, Karen Viskupic, Jennie Rylee, Cindy Busche, Sara Focht, David Cannamela, Annelise Carleton-Hug, James Belthoff, David Wilkins

David E. Wilkins

With funding from the National Science Foundation’s Graduate STEM Fellows in K-12 Education program (GK-12), students from Boise State University’s graduate programs in biology and geosciences gain experience in curriculum development and delivery in a wide range of settings. The project uniquely partners graduate students with educators at three informal science centers that use their settings to focus on science and environmental issues of local, regional, and global importance. Two-three graduate students per year (GK-12 Fellows) are placed at each learning center where they work to create, modify, and deliver learning activities that incorporate local and regional themes as well …

Beyond Multiple Regression: Using Commonality Analysis To Better Understand R2 Results, Russell Warne

Russell T Warne

Multiple regression is one of the most common statistical methods used in quantitative educational research. Despite the versatility and easy interpretability of multiple regression, it has some shortcomings in the detection of suppressor variables and for somewhat arbitrarily assigning values to the structure coefficients of correlated independent variables. Commonality analysis—heretofore rarely used in gifted education research—is a statistical method that partitions the explained variance of a dependent variable into nonoverlapping parts according to the independent variable(s) that are related to each portion. This Methodological Brief includes an example of commonality analysis and equations for researchers who wish to conduct their …

Recommendations For Australia’S Implementation Of The National Emergency Warning System Using Location-Based Services, Anas Aloudat, Katina Michael, Roba Abbas

Professor Katina Michael

Mobile alerts, notifications and location-based emergency warning systems are now an established part of mobile government strategies in an increasing number of countries worldwide. In Australia the national emergency warning system (NEWS) was instituted after the tragic Black Saturday Victorian Bushfires of February 2009. In the first phase, NEWS has enabled the provision of public information from the government to the citizen during emergencies anywhere and any time. Moving on from traditional short message service (SMS) notifications and cell broadcasting to more advanced location-based services, this paper provides executive-level recommendations about the viability of location-based mobile phone services in NEWS …

The Fall-Out From Emerging Technologies: On Matters Of Surveillance, Social Networks And Suicide, M.G. Michael, Katina Michael

M. G. Michael

No abstract provided.

The Fall-Out From Emerging Technologies: On Matters Of Surveillance, Social Networks And Suicide, M.G. Michael, Katina Michael

Professor Katina Michael

No abstract provided.

Ancestral Landscapes Of The Pueblo World, Lesley M. Head

Lesley Head

No abstract provided.

Is It Easy Being Green? On The Dilemmas Of Material Cultures Of Household Sustainability, Chris Gibson, Gordon R. Waitt, Lesley M. Head, Nicholas J. Gill

Lesley Head

In the 1970s ‘greens’ were normally thought of as radicals because of their uncompromising political views about sustainability, non-violence, social justice and grassroots democracy. Sometimes greens were marginalised as ‘tree-huggers’ because of their affinity with the non-human world. Today, in popular discourse, ‘green’ provides the centre of sustainability gravity (Barr 2003). Green has become a definitive reflection of what individuals are to become as both consumers and citizens. It is easy, it is said, to be green. This is evident from product branding to categories used in government survey results to describe the ‘most acceptable’ household practices. But as green …

Changing Cultures Of Water In Eastern Australian Backyard Gardens, Lesley M. Head, Pat Muir

Lesley Head

Research into diverse cultural understandings of water provides important contributions to the pressing global issue of sustainable supply, particularly when combined with analysis of relationships between everyday household practice and larger sociotechnical networks of storage and distribution. Here we analyse semi-structured interviews with 298 people about their 241 backyards in the Australian east coast cities of Sydney and Wollongong, undertaken during the 2002-03 drought. Water emerged as an important issue in both consciousness and practice. In contrast to a number of other environmental issues which stimulate more polarised responses, a commitment to reducing water consumption was shared across the study …

Australian Backyard Gardens And The Journey Of Migration, Lesley M. Head, Pat Muir, E. Hampel

Lesley Head

Gardens have been an important site of environmental engagement in Australia since the British colonization. They are places where immigrant people and plants carry on traditions from their homelands, and work out an accommodation with new social and biophysical environments. We examine the backyard gardens of three contemporary migrant groups in suburban Australia, Macedonian, Vietnamese and British-born, and a fourth group of first generation Australians with both parents born overseas. There is strong emphasis on the production of vegetables in Macedonian backyards, and herbs and fruit in Vietnamese backyards. British backyards were more diverse, some focusing on non-native ornamental flowers …

Living With Trees – Perspectives From The Suburbs, Lesley M. Head, Pat Muir

Lesley Head

A study of suburban backyards and backyarders in Sydney and Wollongong revealed evidence of attitudes and behaviours in relation to trees. Attitudes are characterised under themes that indicate conditions of tolerance and belonging. They include attachment/risk, order/freedom and nativeness/alienness. While love is common, high levels of suspicion and intolerance towards trees in the suburban context are more common. Our findings confirm and throw further light on previous work indicating that many Australians have very partitioned views of the world in relationto where humans and nonhuman lifeforms belong. This partitioning must be understood in conceptual as well as spatial terms.