Physical Sciences and Mathematics Commons^™

A Geospatial Based Decision Framework For Extending Marssim Regulatory Principles Into The Subsurface, Robert Nathan Stewart

Doctoral Dissertations

The Multi-Agency Radiological Site Survey Investigation Manual (MARSSIM) is a regulatory guidance document regarding compliance evaluation of radiologically contaminated soils and buildings (USNRC, 2000). Compliance is determined by comparing radiological measurements to established limits using a combination of hypothesis testing and scanning measurements. Scanning allows investigators to identify localized pockets of contamination missed during sampling and allows investigators to assess radiological exposure at different spatial scales. Scale is important in radiological dose assessment as regulatory limits can vary with the size of the contaminated area and sites are often evaluated at more than one scale (USNRC, 2000). Unfortunately, scanning is …

Estimating Cost Efficiencies Of Propane Use In Broiler Production: Case Study From Savoy, Arkansas And Trnaca Pri Laborci, Slovak Republic, Zuzana Petrikova

Graduate Theses and Dissertations

This study focuses on analyzing the common practice of U.S. broiler farmers to operate on cash basis instead open credit lines for operating cost of propane gas for heating. Data for analysis were taken over from U.S. ABRF at Savoy and Slovak Farm Univerza at Trnava pri Laborci. Predicting the propane gas usage and propane gas cost was analyzed using the OLS model. It describes impact of selected factors on gas usage and cost. The overall purpose of the thesis is to find out which approach from designed scenarios is more economically efficient for farmer: (a) to pre-purchase propane gas …

A Time-And-Space Parallelized Algorithm For The Cable Equation, Chuan Li

Doctoral Dissertations

Electrical propagation in excitable tissue, such as nerve fibers and heart muscle, is described by a nonlinear diffusion-reaction parabolic partial differential equation for the transmembrane voltage $V(x,t)$, known as the cable equation. This equation involves a highly nonlinear source term, representing the total ionic current across the membrane, governed by a Hodgkin-Huxley type ionic model, and requires the solution of a system of ordinary differential equations. Thus, the model consists of a PDE (in 1-, 2- or 3-dimensions) coupled to a system of ODEs, and it is very expensive to solve, especially in 2 and 3 dimensions.

In order to …

Optimal Theory Applied In Integrodifference Equation Models And In A Cholera Differential Equation Model, Peng Zhong

Doctoral Dissertations

Integrodifference equations are discrete in time and continuous in space, and are used to model the spread of populations that are growing in discrete generations, or at discrete times, and dispersing spatially. We investigate optimal harvesting strategies, in order to maximize the profit and minimize the cost of harvesting. Theoretical results on the existence, uniqueness and characterization, as well as numerical results of optimized harvesting rates are obtained. The order of how the three events, growth, dispersal and harvesting, are arranged also affects the harvesting behavior.

Cholera remains a public health threat in many parts of the world and improved …

Synthesis Of A Chemical Probe For Identification Of Ger Receptor Proteins Of Bacillus Anthracis, Hyelee Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bacillus anthracis,a gram positive, endospore-forming, rod-shaped, aerobic bacterium, is the causative agent of anthrax. A key step in the pathogenic cycle is the spore germination, where the dormant spore transforms into a metabolically active cell. This allows B. anthracis to proliferate and secrete toxins. It is believed that spore germination is triggered when small molecules, known as germinants, are recognized by germination (Ger) receptor proteins located in the inner membrane of spores. Most Ger proteins are encoded by tricistronic operons, resulting in three distinct products, the A-, B-, C-subunits. Genomic sequencing showed that B. anthracis has seven ger receptor …

Gene By Bmi Interactions Influencing C-Reactive Protein Levels In European-Americans, Sarah Tudor

Dissertations & Theses (Open Access)

C-Reactive Protein (CRP) is a biomarker indicating tissue damage, inflammation, and infection. High-sensitivity CRP (hsCRP) is an emerging biomarker often used to estimate an individual’s risk for future coronary heart disease (CHD). hsCRP levels falling below 1.00 mg/l indicate a low risk for developing CHD, levels ranging between 1.00 mg/l and 3.00 mg/l indicate an elevated risk, and levels exceeding 3.00 mg/l indicate high risk. Multiple Genome-Wide Association Studies (GWAS) have identified a number of genetic polymorphisms which influence CRP levels. SNPs implicated in such studies have been found in or near genes of interest including: CRP, APOE, APOC, IL-6, …

Aiding Conservation Of The Federally Threatened Scutellaria Montana (Lamiaceae, Large-Flowered Skullcap) Through Abundance Monitoring And Transplantation Studies, Heather Mae Kile

Masters Theses and Doctoral Dissertations

Scutellaria montana Chapm. (large-flowered skullcap) is a federally threatened species endemic to Georgia and Tennessee. This thesis presents conservation work on this species through abundance monitoring at a single site in Catoosa County, Georgia, and transplantation experiments at two sites located in Hamilton County, Tennessee, and Catoosa County, Georgia. Plants naturally occurring in the fixed plots surveyed over seven years had an overall stable growth status, though relatively low floral induction and seedlings. Transplantation revealed influences of abiotic and biotic factors. One transplantation site was fenced to prevent human trampling and apparently discouraged vertebrate grazing, resulting in dramatic flower number …

Reducing Reliance On Supplemental Winter Feeding In Elk (Cervus Canadensis): An Applied Management Experiment At Deseret Land And Livestock Ranch, Utah, Dax L. Mangus

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Wildlife managers have fed elk in North America for nearly 100 years. Giving winter feed to elk can compensate for a shortage of natural winter range and may boost elk populations while also helping prevent commingling with livestock and depredation of winter feed intended for livestock. In contrast to these benefits of supplemental feeding, there are economic and environmental costs associated with feeding, and elk herds that winter on feeding grounds have a higher risk of contracting and transmitting disease. Brucellosis is of primary concern now, and Chronic Wasting Disease may be in the future. Many see the discontinuation of …

Climate And Vegetation Change In The Newberry Mountains, Southern Clark County, Nevada, Ross Joseph Guida

UNLV Theses, Dissertations, Professional Papers, and Capstones

Ecological studies have shown worldwide that vegetation is being affected by climate change. Species are shifting to new elevations and physiographic positions to adapt to changes in their environment. More specifically, paleoecology studies in the Mojave Desert have shown shifting vegetation patterns in response to past warming and precipitation changes. Recent studies have shown mortality among desert plants related to extended drought and warming. However, few studies have shown how the geographic distribution of Mojave Desert species has changed during this most recent period of warming. This study addresses this gap in the literature by focusing on several plant species …

Historical Diversification Of Montane Herpetofauna Within And Between The Sierras Of Mexico, Robert William Bryson Jr.

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Mexican highlands consist of four major mountain ranges spanning most of mainland Mexico. The evolutionary history of the Mexican highlands has been shaped by various geological and climatic events over the past several million years. The relative impacts of these historical events on diversification in montane taxa, however, remains uncertain. I used mitochondrial DNA data from three widely distributed species complexes of lizards as a model system to exemplify the potential roles of Neogene mountain formation and Quaternary climate change on timing and tempo of diversification across the Mexican highlands. My results suggested strong geographic partitioning of genetic variation …

Bringing Biodiversity To Development: Perceptions Of Integrating Eucalyptus And Forest-Corridors Around The Serra Do Brigadeiro, Brazil, Maggie R Stevens

Masters Theses

The Atlantic Forest of south-eastern Brazil is a hot-spot for biodiversity and should be conserved. It is also at the center of the largest municipalities in Brazil and therefore has a severely fragmented landscape. Iracambi, a working farm near the Serra do Brigadeiro state park in Minas Gerais, is working for conservation in an area of intense agricultural production and expanding forestry industry. Most households in this rural area have some amount of eucalyptus on their property and consequently the director of Iracambi is developing the preliminary foundation for a forest corridor program comprised of primarily eucalyptus with the goal …

Non-Thermal Plasma Inactivation Of Bacillus Amyloliquefaciens Spores, Yaohua Huang

Masters Theses

Bacterial spores have remarkable resistance to a variety of harsh conditions, causing spoilage in food industry and becoming the primary bacterial agent in biowarfare and bioterrorism. In this study, inactivation mechanisms of Bacillus amyloliquefaciens (BA) spores by non-thermal plasma (NTP) were investigated by using Fourier-transform infrared spectroscopy (FTIR) as a major tool to exam spores after NTP treatment. Chemometric techniques, such as multivariate classification models based on soft independent modeling of Class Analogy (SIMCA) and Principal Component Analysis (PCA), were employed to identify functional group changes in FTIR spectra. The IR absorbance bands correlated to dipicolinic acid (DPA) decreased after …

The Molecular Mechanism Of Migraine, Kristin Dawn Watson

Theses and Dissertations

Migraine is a common, episodic neurological disorder that includes headache, nausea and hypersensitivity to sensory stimuli. During the headache phase of migraine, migraine patients can be especially hypersensitive to thermal stimuli. The unpredictable and episodic nature of migraine makes it difficult to treat and much of the mechanism of migraine has yet to be elucidated. A T44A substitution in casein kinase 1δ is inherited with migraine with aura. A transgenic mouse model suggests that animals with this mutation exhibit increased sensitivity to thermal stimuli after injection with nitroglycerin (NTG). We performed behavior assays that measure animal responses to thermal stimuli, …

Structures Of Poliovirus And Antibody Complexes Reveal Movements Of The Capsid Protein Vp1 During Cell Entry, Jun Lin

Theses and Dissertations

In the infection process, native poliovirus (160S) first converts to a cell-entry intermediate (135S) particle, which causes the externalization of capsid proteins VP4 and the N-terminus of VP1 (residues 1-53). The externalization of these entities is followed by release of the RNA genome, leaving an empty (80S) particle. Three antibodies were utilized to track the location of VP1 residues in different states of poliovirus by cryogenic electron microscopy (cryo-EM). "P1" antibody binds to N-terminal residues 24-40 of VP1. Three-dimensional reconstruction of 135S-P1 showed that P1 binds to a prominent capsid peak known as the "propeller tip". In contrast, our initial …

Mathematical Modeling And Dynamical Analysis Of The Operation Of The Hypothalamus - Pituitary - Thyroid (Hpt) Axis In Autoimmune (Hashimoto's) Thyroiditis, Balamurugan Pandiyan

Dissertations (1934 -)

This thesis is a mathematical modeling study of the operation of the negative feedback control through the hypothalamus-pituitary- thyroid (HPT) axis in autoimmune (Hashimoto's) thyroiditis. Negative feedback control through the HPT axis is a mechanism in which the high levels of thyroid hormone; free thyroxine (FT4) in the blood inhibits the secretion of the pituitary hormone, thyroid stimulating hormone (TSH) into the blood. Similarly, the low levels of free thyroxine (FT4) sensed by the pituitary gland and then it secretes thyroid stimulating hormone (TSH) into the blood. Autoimmune (Hashimoto's) thyroiditis is a disease in which the immune system turns against …

Novel Ion Trap Made Using Lithographically Patterned Plates, Ying Peng

Theses and Dissertations

A new approach of making ion trap mass analyzers was developed in which trapping fields are created in the space between two ceramic plates. Based on microfabrication technology, a series of independently-adjustable electrode rings is lithographically patterned on the facing surfaces of each ceramic plate. The trapping field can be modified or fine-tuned simply by changing the RF amplitude applied to each electrode ring. By adjusting the potential function applied to the plates, arbitrary trapping fields can be created using the same set of ceramic plates. Unlike conventional ion traps, the electrodes of planar ion traps have a non-equipotential surface, …

Comparison Of Soil Chemistry And Microbial Communities That Inhabit The Rhizosphere Of Native And Non-Native Grasses Of The Lower Rio Grande Valley, Jacqueline Valencia

Theses and Dissertations - UTB/UTPA

Non-native grasses can modify the soils they invade. This study investigated microbial variation among native and non-native grasses in the Lower Rio Grande Valley. We hypothesized that rhizospheres of non-native grasses would support a higher density of microorganisms; therefore microbial communities of invasive plants would exploit more carbon sources than those of native plants. A second hypothesis stated that Streptomyces bacteria from the rhizosphere of non-native grasses would be better competitors. Samples of grasses, and soil from their respective rhizospheres were obtained in Arroyo City, TX. Results indicated a higher bacterial colony density, total activity and number of substrates utilized …

Effects Of 11 Years Of Co2 Enrichment On Root Biomass And Spatial Distribution In A Florida Scrub-Oak Ecosystem, Rachel Eilenfield Schroeder

Biological Sciences Theses & Dissertations

A Florida (USA) scrub-oak ecosystem was exposed to elevated atmospheric CO₂ in open-top chambers from 1996-2007. Minirhizotrons and ground-penetrating radar (GPR) were used to measure fine root (< 2 mm diameter) and coarse root (> 5 mm diameter) biomass, respectively. After 11 years of CO₂ enrichment, there was a trend of greater total root biomass under elevated CO₂. Fine root biomass exhibited a pattern of recovery and steady state throughout the study, with significant CO₂ stimulation observed only after disturbance. Greater root biomass under elevated CO₂ during recovery periods could result in greater carbon inputs belowground, alteration of the soil carbon …

Prairie Restoration And Species Diversity: A Comparison Of Propagation Success Between Seeded And Planted Forbs, Julie A. Widinski

All Student Theses

Prairie ecosystems used to dominate Illinois’ landscapes, providing some of the most organically rich soils in the world, supplying homes to hundreds of native species, and conserving soil and water. The deep rooted forbs prevent water runoff and soil erosion. Economically the prairies have provided medicines, commercial forbs, and aesthetically pleasing landscapes for humans. Society is dependent on the rich soils these prairies have provided for agriculture and for prevention of erosion and water runoff. With less than one tenth of one percent of Illinois prairies still remaining, successful prairie restoration is of the utmost importance. In order to achieve …

Controls On The Formation Of Algal Blooms In The Lower Chesapeake Bay And Its Tributaries, Ryan Eric Morse

OES Theses and Dissertations

Algal blooms occur seasonally in the Chesapeake Bay and its tributaries, and while the consequences of algal blooms have been qualitatively and quantitatively assessed, the causes of algal blooms and mechanisms of bloom initiation are still not well understood despite decades of research. In order to understand nutrient dynamics and other factors that promote the initiation of algal blooms, the Lafayette River, a tidal sub-estuary of Chesapeake Bay that experiences seasonal algal blooms, was sampled daily in the fall of 2005. Three phytoplankton blooms (Chlorophyll a concentrations exceeding twice the average of monthly measurements from 2000-2009) occurred during this period, …

Investigating A Model Reversed-Phase Liquid Chromatography Stationary Phase With Vibrationally Resonant Sum Frequency Generation Spectroscopy, Arthur D. Quast

Theses and Dissertations

Reversed-phase liquid chromatography (RPLC) is a widely used technique for analytical separations but routinely requires empirical optimization. Gaining a better understanding of the molecular reasons for retention may mean more efficient separations with fewer trial and error runs to obtain optimized separations. Vibrationally resonant sum frequency generation (VR-SFG) is a surface specific technique that has allowed for in situ examination of model RPLC stationary phases under various solvent and pressure conditions. In order to improve on past work with model RPLC stationary phases two challenges had to be overcome. First, improved vibrational mode assignments of the C18 stationary phase were …

Progress Toward Theonellamide F, Jennifer Dawn Bettale

Theses and Dissertations

Theonellamide is a bicyclic peptide isolated from a marine sponge, which shows interesting biological activity. It contains several unnatural amino acids, among which are (2S,3R)-3-hydroxyasparagine (L-erythro-β-hydroxyasparagine) (β-OHAsn) and τ-L-histindino-D-alanine (τ-HAL). Although there were previous synthetic efforts toward each of these unnatural amino acids, the efforts were not ideal due to expensive starting material, time-consuming steps, and poor regioselectivity. The presented work demonstrates an inexpensive, enantioselective synthesis of β-OHAsn, which can be completed in a matter of weeks, as well as several attempts at a novel regiospecific approach toward τ-HAL, including work on a model study.

Camera Study For Mammalian Carnivore Presence Across Seasons In Montana De Oro State Park, San Luis Obispo County, Ca, Samuel R. Young

Natural Resources Management and Environmental Sciences

Montana de Oro (MDO) is one of the largest state parks in California. Little is known however about its wildlife or their habits. Large predators such as mountain lion (Puma concolor) and black bear (Ursus americanus), and non–native species such as red fox (Vulpes vulpes) and feral pig (Sus scropha) are of management concern because of their potentially dramatic ecological roles. Cameras were deployed at 5 sites along the Coon Creek hiking trail in spring (May 3–June 7), summer (July 15–August 19), and fall (October 10–November 23) sessions with the goal of …

Old Father Hudson: The Three Stages Of Environmental Activism In The Hudson River Valley, Gregory P. Cannillo

Honors Theses

Consequences of development have threatened the health of the Hudson River for decades. These have included the prospect of destroying scenic value of the Hudson River Valley with the a hydroelectric power plant on Storm King Mountain, as well as the pollution of the river itself by a variety of industrial sources. Since the 1960s, a long lineage of environmental activism in the Hudson River Valley has emerged to address those issues. The example of the Hudson River supplies an excellent case study of how environmental issues began to be addressed in the later half of the 20th century. I …

Sustainable Food: New York Organic Dairy Market Conditions And Recommendations For Policy Reform, Dylan H. Hawkins

Honors Theses

This paper questions the sustainability of the American dairy industry through an examination of the current organic milk industry of New York State, with special attention paid to three interests: consumer welfare, farmer welfare, and the environment. Many consumers envision an agrarian ideal of grazing cows on pasture when they think of a dairy farm; milk-marketing companies often perpetuate this image. Unfortunately, most dairy cows in America do not enjoy such idyllic lives. History shows that consolidation of the American food system has led to major transformations in dairy farming. As a result, consumers have had limited access to high …

Farmers Motivations To Practice Sustainable Agriculture, Kimberly A. Floeser

Honors Theses

An increasing awareness of human and environmental health issues and the destruction of family farms and rural communities have caused a significant change in the way many farmers, consumers, and policy‐makers are thinking about and relating to food, the results of which can be seen largely in the growth of the organic and sustainable food industry. This paper attempts to examine and explain farmers’ attitudes towards sustainable agriculture, and their motivations to use sustainable methods of production. A survey was distributed to 533 farms that are members of the Northeast Organic Food Association of New York (NOFA‐NY). The data obtained …

The Conservation And Habitat Ecology Of Antillean Manatees (Trichechus Manatus Manatus) In The Drowned Cayes Area Of Belize, Central America, Katherine Spencer Lacommare

Graduate Doctoral Dissertations

The Drowned Cayes area of Belize, Central America is regionally important for the conservation of Antillean manatees in the Caribbean (Lefebvre et al. 2001; Quintana-Rizzo & Reynolds 2008). These islands are increasingly threatened by human activities such as tourism, development and population growth. The objective of this dissertation is to evaluate manatee habitat use and status in this area. The 5 specific objectives are to examine manatee (1) distribution in the Drowned Cayes, (2) use of seagrass beds and forage selection, (3) resting habitat use and selection (4) response to disturbance, and (5) trends in abundance and to suggest a …

Fast Program For Sequence Alignment Using Partition Function Posterior Probabilities, Meera Prasad

Theses

The key requirements of a good sequence alignment tool are high accuracy and fast execution. The existing Probalign program is a highly accurate tool for sequence alignment of both proteins and nucleotides. However, the time for execution is fairly high. The focus is therefore, to reduce the running time of the existing version of Probalign, maintaining its current accuracy level.

The thesis conducts a detail analysis of the performance of Probalign to bring down the running time of the existing code. A modified version of Probalign, Version 1.4 is released. A new program for sequence alignment with faster computation is …

Characterization Of Esterase Activity From The Bacteria, Francisella Tularensis, The Causative Agent Of Tularemia, Leigh Anna Weston

Undergraduate Honors Thesis Collection

Francisella tularensis is the bacteria responsible for causing the disease tularemia and is listed as one of the top three-biowarfare agents. Among the proteins essential to the virulence and infectivity of F.tularensis are multiple esterases, which are enzymes that break down various ester, thioester, and amide bonds. In this project, the catalytic activity, substrate speci fi city, and structure of a putative esterase from F.tularensis was studied. Latent fluorophores based on the molecule, fluorescein, were unmasked by the enzymatic activity of the esterase and the increase in fluorescence was measured over time to determine how well the e tcrase recognized …

Chiral Recognition Study Of A Bimolecular Process In Amino Acid Chiral Ionic Liquids, Laurel Millikan Heckman

Undergraduate Honors Thesis Collection

In this study, chiral ionic liquid (CIL) solvents were prepared and tested for their chiral discrimination ability by probing with luminescence quenching. The CIL's were also tested for their impurities, viscosity and density. These experiments will help to determine the ability of CIL's to act as solvents in asymmetric catalysis. The chiral ionic liquids in this study were composed of amino acid methyl ester cations and bis(trifluoromethane) sulfonimide or bistri flimide anions (i.e. I-alanine methyl ester bistriflimid e, d-alanine methyl ester bistr iflim ide and I-leuci ne methyl ester bistriflimde). Circularly polarized luminescence (CPL) and its quenching in the chiral …