Veterinary Toxicology and Pharmacology Commons^™

Agribusiness Sheep Updates - 2004 Part 2, Anyou Liu, Clinton Revell, Phil Nichols, Brad Nutt, Darryl Clements, Lucy Anderton, Stephen Gherardi, Chris Oldham, Paul Sanford, John Gladman, G. E. Donald, A. Edirisinghe, D. A. Henry, S. P. Gittins, R. C. G. Smith, Roy Butler, Kelly Pearce, David Masters, David Pethick, Andrew Thompson, Ken Hart, Johan Greeff, Beth Paganoni, Rachel Kirby, Matt Ryan, Kira Butler, Roger Heggarty, David Hopkins, Samantha Giles, Tom Plaisted, Mark Ferguson, Darren Gordon, John Young, Sandra Brown, Ian Mcfarland, John Archer, John Milton, Rob Davidson, Graeme Martin, David Lindsay, Johnathan England, Mandy Curnow, Karina P. Wood, Ashley K. White, B. Lloyd Davies, Paul M. Carberry, Mark Hyder, Mike Freer, Andrew Van Burgel, Kazue Tanaka, Andrew Peterson, Roger Wiese, Gonzalo Mata, Evan Burt, Amanda Miller, Anne Bennett, Felicity Flugge, Amir Abadi, Perry Dolling, Dean Thomas, Mike Ewing, David Lindsay, Emma Kopke, E. A. Dowling, E. K. Crossley, Brien (Ben) E. Norton, John Karlsson, Geoff Pollott, Diana Fedorenko, Darryl Clements, Robert Beard, Brown Besier, Una Ryan, Caroline Bath

Sheep Updates

Precision Pastures

Using Species Diversity to Improve Pasture Performance Anyou Liu and Clinton Revell, Department of Agriculture, Western Australia

New Annual Pasture Legumes for Sheep Graziers Phil Nichols, Angelo Loi, Brad Nutt and Darryl McClements Department of Agriculture Western Australia

Pastures from Space – Can Satellite Estimates of Pasture Growth Rate be used to Increase Farm Profit? Lucy Anderton, Stephen Gherardi and Chris Oldham Department of Agriculture Western Australia

Summer-active Perennial Grasses for Profitable Sheep Production Paul Sanford and John Gladman, Department of Agriculture, Western Australia

Pastures From Space – Validation Of Predictions Of Pasture Growth Rates DONALD, G.E^{.A …}

The Evidence For Pain In Fish: The Use Of Morphine As An Analgesic, Lynne U. Sneddon

Veterinary Science and Medicine Collection

This paper discusses the evidence for pain perception in fish and presents new data on morphine analgesia in fish. Recent anatomical and electrophysiological studies have demonstrated that fish are capable of nociception, the simple detection of a noxious, potentially painful stimulus and the reflex response to this. To prove pain perception, it must be demonstrated that an animal’s behaviour is adversely affected by a potentially painful event and this must not be a reflex response. The present study examined the acute effects of administering a noxious chemical to the lips of rainbow trout (Oncorhynchus mykiss) to assess what changes occurred …

Lupin Stubbles : Getting The Best With Weaner Sheep, Keith Croker, Colin Mcdonald, Jeremy Allen

Journal of the Department of Agriculture, Western Australia, Series 4

Sweet lupins are now grown on about a million hectares in Western Australia each year. If half of the State's seven million weaners were grazed as recommended on half of the lupin stubbles, it could generate about $15 million from reduced supplementary feeding, greater wool production and other advantages. But correct management is important, particularly knowing when to take weaners out. Research by the Department over the last five years is now indicating how this should be done.

Phomopsis-Resistant Lupin Stubbles As Feed For Weaner Sheep, Colin Mcdonald, Keith Croker, Jeremy Allen

Journal of the Department of Agriculture, Western Australia, Series 4

The breeding of sweet, narrow-leafed lupins with increased resistance to Phomopsis leptostromiformis, the fungus that causes lupinosis in sheep, is a breakthrough for the summer nutrition of weaner sheep. The new resistant varieties, Gungurru for the medium (325 to 450 mm) rainfall areas and Yorrel for low rainfall areas (less than 325 mm), were released by the Department of Agriculture in 1988.

This article discusses progress in a four-year project which is examining liveweight and wool production of weaners grazing Gungurru stubbles.

The Sandplain Lupin : Its Nutritional Value And Grazing Management, P W. Morcombe

Journal of the Department of Agriculture, Western Australia, Series 4

The sandplain lupin or Western Australian blue lupin (Lupinus cosentinii) was introduced to the West Midlands at the turn of the last century. Since that time it has been used as a self-regenerating summer forage for sheep and cattle.

Being deep rooted, it has adapted well to the sandy soils from Perth to Northampton, and plantings now cover more than 100,000 ha.

As few other improved pasture species will persist on these deep sands the sandplain lupin provides an important source of summer feed for grazing livestock. A stand can be grazed throughout summer at stocking rates of 10 to …

Effects Of Methylxanthines On Newborn Rat Respiration, Craig Gatto

Masters Theses

Methylxanthines (MX), such as theophylline, are commonly used in the treatment of recurrent apnea due to their stimulant effects on the respiratory center. Structure-activity studies have demonstrated that substitution of alkyl groups on the 3-position of the xanthine nucleus results in increased bronchodilator potency, while substitution on the 1-position is important for adenosine antagonism and CNS stimulation. Three different alkylxanthines were studied to determine the structural requirements for respiratory stimulation. Respiratory rates and volumes were determined in 4- to 7-day-old rats using a volume displacement body plethysmograph. Measurements were made before and at 5 minute intervals after subcutaneous (s.c.) injection …

The Effects Of Xanthine And Adenosine Analogs On Rat Pup Diaphragmatic Contractility, Liam C. Farrell

Masters Theses

Methylxanthines are commonly used in the treatment of respiratory disorders such as asthma, apnea of prematurity and Cheyne-Stokes respiration. Recently, certain methylxanthines have been found to potentiate the contraction of the diaphragm and increase contraction strength of the fatigued diaphragm. The mechanism of action of the methylxanthines is unknown. Three theories have been proposed but each has its supportive and negative points. One theory is that methylxanthines inhibit cyclic AMP phosphodiesterase (PDE) which facilitates contraction by increasing cyclic AMP levels in the cell. Another theory is that methylxanthines antagonize adenosine, thus blocking the adenosine-induced inhibition of contraction. The third theory …

T-61 Use In The Euthanasia Of Domestic Animals: A Survey, Andrew N. Rowan

Veterinary Science and Medicine Collection

A variety of techniques have been proposed and employed for the killing of domestic animals but relatively few have survived as suitable agents for euthanasia-namely, the induction of painless, suffering-free death. Some agents, such as strychnine, curariform agents, or potassium salts cause suffering while others have other disadvantages. 'lbday, dogs and cats are commonly euthanatized with sodium pentobarbital or with T-61 which is a mixture of a central nervous system narcotic, a paralytic agent, and a local anesthetic. The use of T-61 was first reported in the United States in 1963 (Quin 1963). The substance gradually became more popular because …

Review Of Literature On Use Of T-61 As An Euthanasic Agent, Laura Dalia Barocio

Veterinary Science and Medicine Collection

The tools of evaluating the degree of distress in animals being killed include electroencephalography (EEG), electrocardiography (ECG), and measurement of blood pressure and respiration. Sound clinical and behavioral observations should also not be abandoned in the evaIuation process.

There are many methods which may be employed to reach the same end results, but the ideal method should satisfy several criteria: 1. It should be painless; 2. It should cause unconsciousness instantaneously and death within minutes; 3. It should not cause undue anxiety, alarm, fear, panic, behavior, struggling, vocalization, muscle spasms or clinical signs of automatic activation (e.g., convulsions) before unconsciousness; …

Prostaglandin F2a Induced Nest Building Behavior In The Non-Pregnant Sow, And Some Welfare Considerations, Judith K. Blackshaw

Agribusiness Collection

Nest building behavior, induced with intramuscular injections of prostaglandin F2_a (PGF2_a), was studied in non-pregnant sows. Acute effects, which included salivation, scratching, vomiting, defaecation and ataxia, were also recorded. Sows (Large White x Landrace) were housed in two different environments; six sows in bare pens and six sows in pens provided with bedding material. In all cases except one (bare pen) nest building sequences of differing intensities were recorded. Welfare suggestions include questioning the justification of using a drug (PGF2_a) in pig husbandry, which has unpleasant acute effects, and the suggestion that the provision of …

Toxic Ferns Of Western Australia, T E H Aplin, P Steele, M C. Nottle

Technical Bulletins

Botanical descriptions and notes on the distribution of six species of ferns are given. These plants contain the enzyme thiaminase, which may induce thiamin deficiency, or other constituents toxic to animals. The clinical signs of both thiamin deficiency and fern toxicity in affected livestock are described.

Bulletin 3967 - Cyanogenetic Plants Of Western Australia, T E H Aplin

Bulletins - 3000 - 3999

This article deals with those native, naturalized and cultivated plants, which by virtue of contained cyanogenetic glycosides, are known to be poisonous or potentially poisonous to livestock in Western Australia.

Cyanogenetic glycosides are chemical compounds which contain a cyanogen (cyanide) radical combined with a sugar molecule. The sugar moiety may differ in glycosides obtained from different plants, and as a consequence glycosides from different plants, containing different sugar moieties, may be given different names.

When a cyanogenetic glycoside is broken down by enzyme action, through injury to the plant or by microbial action in the digestive system of the animal, …

Lupinosis : A Disease Still With Us, Jeremy G. Allen, P. Mcr. Wood, K. P. Crocker, J. Hamblin

Journal of the Department of Agriculture, Western Australia, Series 4

Current research on lupinosis continues to reveal what a complex problem it is, but the improved understanding should help to reduce losses.

Controlling Annual Ryegrass Toxicity, C H. Trotman

Journal of the Department of Agriculture, Western Australia, Series 4

Eight years of intensive work has changed annual ryegrass toxicity from an unknown killer to a manageable problem.

Ryegrass Disease Could Spread, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

The disease annual ryegrass toxicity kills sheep and cattle grazing pastures which contain infected annual ryegrass. In Western Australia the first confirmed outbreak was in 1968 in the Gnowangerup area.

The disease has noe spread over a range of 450 kilometres and with a total area of perhaps 100 000 hectares. because annual ryegrass is the major sown pasture grass in W.A. the disease could spread throughout the South-West.

There are some precautions that can be taken.

Bulletin No 3863 - Plants Which Cause Kimberley Horse Disease, A. L. Payne

Bulletins - 3000 - 3999

Crotalaria crispata and Crotalaria retusa (Rattlepod), two plants responsible for Kimberley horse disease*, are, unfortunately, fairly widespread throughout the Kimberleys. Both species are apparently toxic in all stages of growth.

This bulletin is to assist pastoralists to:-

• Identify the two plants;

• Recognise the type of country and conditions under which they grow; and

• Locate horse paddocks on country where the plants are least likely to occur.

Lupinosis And Rates Of Stocking Of Lupin Stubbles, K P. Croker, J. G. Allen, C. R. Lester, R. B. Guthrie

Journal of the Department of Agriculture, Western Australia, Series 4

Lupin stubbles provide valuable summer sheep feed but under some conditions the fungus Phomopsis rossiana (for which lupins are the host plant) produces a toxin that causes lupinosis. Results from research at Badaingarra Research Station over the 1973-74 and 1974- 75 summers have shown that sheep liver damage associated with lupin stubble grazing is likely to be more severe at high than low stocking rates.

Treflan And The Oxygen Consumption Of Green Sunfish (Lepomis Cyanellus), Barbara Jo Warner

Masters Theses

Oxygen consumption rates of 51 green sunfish (Lepomis cyanellus, Rafinesque) were monitored over five hours exposure to Treflan E.C. concentrations of 0, 0.32, 0.56, 1.0, and 2.0 ppm. There was a great variation in the responses of the fish at each concentration; and Student's t-tests revealed no significant differences. However, graphs of the mean hourly oxygen consumption rates showed certain trends. During the fifth hour of exposure, there appears to be an acclimation to the Treflan at concentrations of 0.32 and 0.56 ppm; but no such acclimation at the higher concentrations of 1.0 and 2.0 ppm. Hourly oxygen …

Pesticide Residues In The Illinois Wild Turkey, John M. Bridges

Masters Theses

Adipose tissue from 55 turkeys, killed during the 1974 hunting season in southern Illinois, was grouped by age and location of the birds, and the pesticide concentrations in them were determined by gas/liquid chromatography. Twelve different pesticides were identified in the samples with only four, total DDT, heptachlor epoxide, toxaphene, and linuron, being present in all samples. Concentrations ranged from 0.02 ppm to 0.88 ppm.

Development Of A Selective Bait For Rabbits, A J. Oliver, S. H. Wheeler

Journal of the Department of Agriculture, Western Australia, Series 4

It has long been recognised that a means of killing rabbits selectively in the presence of stock would be a major advance in rabbit control. It would enable a whole farm to be treated for rabbit control at one time, saving operational costs and cutting down reinfestation of rabbits into treated areas from untreated areas.

A literature search and some pilot trials indicated that indandione derivatives were more toxic to rabbits than to ruminants.

Pindone (2- pivalyl-l,3-indandione) was selected for evaluation.

Annual ('Wimmera') Ryegrass Toxicity, Geoffrey A. Pearce, O. M. Goss, P. H. Berry, J. L. Wise

Journal of the Department of Agriculture, Western Australia, Series 4

Because annual ryegrass is one of the most widespread pasture plants in Western Australia, annual ryegrass toxicity is a threat to livestock in many agricultural areas—even though the area now affected is small.

The problem is being intensively studied by the Department of Agriculture and a working group has been set up to investigate potential control measures.

In this article the group reviews the problem and reports progress in its investigations to the end of 1973.

Wimmera Ryegrass Toxicity, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

Wimmera ryegrass toxicity has been reported for many years to affect sheep and occasionally cattle in New Zealand, South Australia and the United States of America.

In Western Australia, occasional reports since 1959 and severe outbreaks of staggers in the Katanning- Gnowangerup areas over the last two years prompted the investigation reported below.

Fumigation And Rabbit Control, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

Fumigation has been a valuable tool in Australian rabbit control for over 70 years, because of its economy and efficiency compared with methods such as shooting and trapping.

Even now, while it is not as economical as 'one-shot' baiting, fumigation remains a valuable initial control effort because it is not affected by season and does not require shifting of stock.

Poison Plants Of Western Australia : The Toxic Species Of The Genera Gastrolobium And Oxylobium : Thick-Leaf Poison (Gastrolobium Crassifolium Benth.), Narrow-Leaf Poison (Gastrolobium Stenophyllum Turcz.), Mallet Poison (Gastrolobium Densifolium C.A. Gardn.), Wall-Flower Poison (Gastrolobium Grandifolorum F. Muell), T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

THIS article deals with three species of Gastrolobium which are found in the south-west region of Western Australia. Two of these extend into the Eyre District, the third species is found in the Lake Grace area. The fourth species, Wall-flower poison, is the only toxic species of the genus found outside the State.

Cotton Bush (Asclepias Fruticosa L.) : Garden Plant Now A Noxious Weed, G R W Meadly

Journal of the Department of Agriculture, Western Australia, Series 4

THE cotton bush is native to South Africa but is now naturalised in most tropical and sub-tropical countries of the world. Its spread is, in no small measure, due to being grown frequently as a garden subject.

Calotropis Or Rubber Tree (Calctropis Procera (Linn.) Dryand), G R W Meadly

Journal of the Department of Agriculture, Western Australia, Series 4

TWO SPECIES of Calotropis have been introduced to the northern parts of Western Australia. They are closely related in most respects but differ in one fundamental feature which decides their significance as undesirable plants.

Wildlife Hazards From 1080 Baiting, A R. Tomlinson, C. D. Gooding

Journal of the Department of Agriculture, Western Australia, Series 4

ONE-SHOT oat baiting with sodium fluoroacetate (1080) is a relatively safe method of trail baiting rabbits.

The hazard to wildlife is small and every effort is made to further reduce the hazard by selective application of the poison.

Poison Plants Of Western Australia : The Toxic Species Of The Genera Gastrolobium And Oxylobium : Wodjil Poison (Gastrolobium Floribundum S. Moore) Breelya Or Kite-Leaf Poison (Gastrolobium Laytonii J. White) Roe's Poison (Oxylobium Spectabile Endl.) Granite Poison (Oxylobium Graniticum S. Moore), T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

THIS article deals with four species which are found in the pastoral area although three of them are also present in the agricultural area.

Lupins In Western Australia. 5. The Grazing Value Of Green And Mature Lupins, John Sylvester Gladstones

Journal of the Department of Agriculture, Western Australia, Series 4

WHETHER or not lupins are grown primarily as a grain crop, grazing of standing crops and harvested stubbles will continue to be an important use. This article examines the uses of sweet lupins for forage, and the main problem of lupin grazing, lupinosis.

Know Your Poison Plants : Characteristics Of Poison Plants Of The Genera Oxylobium And Gastrolobium, T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

Characteristics of poison plants of the genera Oxylobium and Gastrolobium