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Small or Companion Animal Medicine Commons™
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Articles 1 - 24 of 24
Full-Text Articles in Small or Companion Animal Medicine
Assessment Of Hind Limb Muscle Activity After Stair-Climbing In A Dog Using 18f-Fdg Pet/Ct: A Case Report, Heesoo Ahn, Seungho Lee, Yoocheol Shin, Byoungho An, Dongwook Kim, Byeong-Teck Kang, Gonhyung Kim
Assessment Of Hind Limb Muscle Activity After Stair-Climbing In A Dog Using 18f-Fdg Pet/Ct: A Case Report, Heesoo Ahn, Seungho Lee, Yoocheol Shin, Byoungho An, Dongwook Kim, Byeong-Teck Kang, Gonhyung Kim
The Thai Journal of Veterinary Medicine
Accurate assessment of functional muscle activation is important for planning rehabilitation exercises in canine patients. Conventional methods, such as electromyography and gait analysis, have limitations in evaluating deep muscles and providing a comprehensive assessment of muscle activity. This case study used 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) to assess hind limb muscle activity in a dog after stair-climbing exercise. A 4-year-old castrated male Beagle underwent 1 h of stair-climbing exercise followed by FDG PET/CT scanning. Increased FDG uptake was observed in multiple hind limb muscles, particularly the gluteus medius and quadratus femoris muscles. The quadratus femoris, a deep …
Minimally Invasive Percutaneous Endoscopic Foraminotomy And Discectomy In A French Bulldog With Intervertebral Disc Extrusion, Tanhatai Krajarngjang, Luksamee Limpongsai, Panutda Darapong, Woraphanit Sonbanpai, Mataya Taweechart
Minimally Invasive Percutaneous Endoscopic Foraminotomy And Discectomy In A French Bulldog With Intervertebral Disc Extrusion, Tanhatai Krajarngjang, Luksamee Limpongsai, Panutda Darapong, Woraphanit Sonbanpai, Mataya Taweechart
The Thai Journal of Veterinary Medicine
A six-year-old female French Bulldog was referred for neurological diagnostic tests and treatment for progressive paraparesis over an 8-day period. The dog had a history of intervertebral disc extrusion (IVDE) surgical correction two years prior. Neurological examination revealed T3–L3 myelopathy. Magnetic resonance imaging of the thoracolumbar spine confirmed IVDE with spinal cord compression at T13–L1. A minimally invasive percutaneous endoscopic foraminotomy and discectomy (PEFD) was performed to remove the extruded disc material. The patient regained the ability to stand and showed voluntary limb movement 48 hours post-surgery. At the 4-week follow-up, the patient showed a complete recovery to her baseline …
Ultrasound-Guided Percutaneous Sclerotherapy Of A Canine Hepatic Cyst Using Lower-Concentration Ethanol: A Case Report, Minyoung Kim, Dongyeong Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee
Ultrasound-Guided Percutaneous Sclerotherapy Of A Canine Hepatic Cyst Using Lower-Concentration Ethanol: A Case Report, Minyoung Kim, Dongyeong Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee
The Thai Journal of Veterinary Medicine
A 10-year-old female Pomeranian was referred after a hepatic cyst was incidentally identified during a routine health check. Ultrasound-guided simple drainage was initially performed, and cytological examination of the aspirated fluid confirmed a simple cyst. However, the cyst re-expanded to its original size within 2 weeks. Therefore, ultrasound-guided percutaneous sclerotherapy was elected using lower-concentration ethanol (83%), a readily available medical disinfectant, rather than conventional high-concentration ethanol. Approximately 50% of the aspirated volume was replaced with 83% ethanol and retained for 20 min to achieve effective epithelial ablation. Post-procedural follow-up revealed a transient increase in cyst size and serum alanine aminotransferase …
Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan
Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan
The Thai Journal of Veterinary Medicine
The objectives of this study were to quantify temporal changes in prostatic volume and serum CPSE concentrations in dogs with benign prostatic hyperplasia (BPH) (n = 6) following surgical castration, and to evaluate the potential of CPSE as a biomarker for monitoring prostatic regression. Prostatic volume was determined by transabdominal ultrasonography, and serum CPSE concentrations were measured at baseline (Week 0) and at Weeks 1, 2, and 4 postcastration. The mean (±SE) prostatic volume before castration was 11.4 ± 1.9 cm3 and decreased significantly to 6.3±1.1 cm3 by Week 1 (P < 0.001), representing a reduction to approximately 56% of the baseline value. Smaller progressive declines were observed at subsequent time points up to Week 4 (P > 0.05). In parallel, serum CPSE concentrations dropped …
Computed Tomography Features For Differentiating Mast Cell Tumors And Soft Tissue Sarcomas In Subcutaneous Masses In Dogs, Seri Hong, Daji Noh, Kija Lee, Hojung Choi, Youngwon Lee, Sooyoung Choi
Computed Tomography Features For Differentiating Mast Cell Tumors And Soft Tissue Sarcomas In Subcutaneous Masses In Dogs, Seri Hong, Daji Noh, Kija Lee, Hojung Choi, Youngwon Lee, Sooyoung Choi
The Thai Journal of Veterinary Medicine
This study aimed to investigate the computed tomography (CT) features of mast cell tumors (MCTs) and soft tissue sarcomas (STSs) in subcutaneous masses of dogs and to identify distinguishing characteristics between these two tumor types. This retrospective, multicenter study included 22 dogs with subcutaneous masses diagnosed as MCTs (n = 11) or STSs (n = 11) via fine needle aspiration or excisional biopsy. The CT features were evaluated based on four categories: location, morphological characteristics (including shape, margin, capsulation, size, and long axis to short axis (L/S) ratio of the lesion), internal parenchymal characteristics (including cavitation, vascularization, mineralization, homogeneity and …
Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna
Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna
The Thai Journal of Veterinary Medicine
New Zealand green-lipped mussel (Perna canaliculus) is a shellfish with a green shell containing many types of fatty acids, especially polyunsaturated fatty acids (PUFAs). The aim of the present study was to investigate the safety of dietary PUFAs supplementation on blood hematology, chemistry and coagulogram pancreatic enzymes in dogs and cats. Twelve healthy beagle dogs and healthy mature cats were used in these studies. Complete randomized block and triplicate 4×4 Latin square designs were used for these dog and cat safety studies, respectively. Experimental diets composed of sham control (0X) and 3 treatment groups, including 1X, 3X, and …
Successful Transcatheter Edge-To-Edge Mitral Valve Repair Via Minithoracotomy In Canine Myxomatous Mitral Valve Disease: Case Report, Anusak Kijtawornrat, Pasakorn Brikshavana, Suphanut Kulabsri, Varit Wijitratanagorn, Nilubol Booncharoensombat, Phanupong Chinnabrut, Wutti Bunjerdsuwan, Natrada Rujivipat, Nakkawee Saengklub
Successful Transcatheter Edge-To-Edge Mitral Valve Repair Via Minithoracotomy In Canine Myxomatous Mitral Valve Disease: Case Report, Anusak Kijtawornrat, Pasakorn Brikshavana, Suphanut Kulabsri, Varit Wijitratanagorn, Nilubol Booncharoensombat, Phanupong Chinnabrut, Wutti Bunjerdsuwan, Natrada Rujivipat, Nakkawee Saengklub
The Thai Journal of Veterinary Medicine
Transcatheter edge-to-edge mitral valve repair (TEER) for the correction of mitral regurgitation (MR) due to myxomatous mitral valve disease (MMVD) stage B1 in a dog by a hybrid intervention technique via minithoracotomy was first reported in Thailand and Southeast Asia. The dog did not show any clinical signs related to congestive heart failure (CHF). Physical examination revealed systolic murmur grade III/VI. Electrocardiographs were recorded and showed normal sinus rhythm. A thoracic radiograph revealed normal size and shape of the heart (VHS 10.9) and diffuse bronchial pattern in the lungs. A definitive diagnosis of MMVD was made by echocardiography. The dog …
Integrated Western And Traditional Chinese Medicine Therapy In A Dog With Acute Pancreatitis, Chen-Yin Liao, Cheng-Hung Lai
Integrated Western And Traditional Chinese Medicine Therapy In A Dog With Acute Pancreatitis, Chen-Yin Liao, Cheng-Hung Lai
The Thai Journal of Veterinary Medicine
A 23kg, 12-year-old intact male Siberian Husky crossbred dog was brought to the animal hospital on October 25, 2020 due to sudden anorexia, vomiting and praying posture for two days. After physical examination, completed blood count (CBC), serum biochemistry profile, canine SNAP cPL test, abdominal radiography and ultrasonography were performed for differential diagnosis. According to clinical symptoms, medical history, and diagnostic test results, it was diagnosed as acute pancreatitis (AP). Integrated Western and traditional Chinese medicine therapy was used, including supporting treatment, aquapunture and traditional Chinese herbal formulas. The clinical signs showed significant improvement after treatment. The results indicated that …
An Undetermined Osteoporotic Disease Managed With Im Rod In A Dog, Hyejong Oh, Byoungho An, Dongwook Kim, Heesoo Ahn, Dongwoo Chang, Gonhyung Kim
An Undetermined Osteoporotic Disease Managed With Im Rod In A Dog, Hyejong Oh, Byoungho An, Dongwook Kim, Heesoo Ahn, Dongwoo Chang, Gonhyung Kim
The Thai Journal of Veterinary Medicine
Osteoporosis is a systemic bone disorder characterized by decreased bone density, which can weaken bone strength and increase the risk of fractures. Osteogenesis imperfecta (OI), one of the main causes of osteoporosis in children, results in fragile bones and multiple fractures. The present study documented the case of a dog with an undetermined osteoporotic disease managed with intramedullary rod fixation. A 3-month-old intact male Alaskan Malamute dog, weighing 11.6 kg, was presented with lameness in the left pelvic limb. Radiography revealed left pelvic and femoral fractures, and the cortex of the long bones was thin. On CT scanning, a significant …
Synchronous Tri-Cavitary Biphasic Malignant Mesothelioma In A Dog Presenting With Dyspnea, Nawarus Prapaiwan, Tawewan Issarankura Na Ayudhaya, Poonavit Pichayapaiboon, Onrampha Tanglakmankhong
Synchronous Tri-Cavitary Biphasic Malignant Mesothelioma In A Dog Presenting With Dyspnea, Nawarus Prapaiwan, Tawewan Issarankura Na Ayudhaya, Poonavit Pichayapaiboon, Onrampha Tanglakmankhong
The Thai Journal of Veterinary Medicine
Malignant mesothelioma is an uncommon tumor that has a challenging diagnosis and a tendency for late diagnosis. A 7-year-old intact male dog presented with respiratory distress. Thoracic radiography revealed pleural effusion and bone reactions at multiple ribs. A computerized tomography scan with rib biopsy was suggested as a diagnosis plan. Unfortunately, the dog died. Gross pathological findings demonstrated multifocal to coalescing, pinkish-white firm masses scattered over the parietal pleural surface, extended to the serosa of the diaphragm and the pericardium, making them adhere to each other and causing the coalescence of a white irregular mass at the diaphragm. Multiple white …
Lingual Histiocytic Sarcoma In A Dog: A Case Report, Seulgi Bae
Lingual Histiocytic Sarcoma In A Dog: A Case Report, Seulgi Bae
The Thai Journal of Veterinary Medicine
An 8-year-old spayed Maltese dog was presented for the evaluation of a lingual mass. The dog had excessive drooling and dysphagia. Oral examination revealed a soft, fluctuating mass at the left side of the tongue. Computed tomography showed a 21 × 32 × 66 mm lingual mass and enlarged left medial retropharyngeal lymph node. On cytology of the lingual mass, a round cell tumor was suspected; however, it was not responsive to glucocorticoid therapy. Because of severe complications, glossectomy and lymphadenectomy were performed; unfortunately, the patient died because of dyspnea in the postoperative period. Histopathologic examination and immunohistochemistry revealed lingual …
Surgical Treatment Of Intra-Abdominal Vaginal Cyst Severely Adhered To Associated Organs In A Dog, Nithida Boonwittaya, Anchisa Suvisit, Piraya Jaiyangyeun, Wallaya Phongphaew, Kasamapohn Hutachinda
Surgical Treatment Of Intra-Abdominal Vaginal Cyst Severely Adhered To Associated Organs In A Dog, Nithida Boonwittaya, Anchisa Suvisit, Piraya Jaiyangyeun, Wallaya Phongphaew, Kasamapohn Hutachinda
The Thai Journal of Veterinary Medicine
A twelve-year-old female Shih Tzu was presented for investigation and treatment of a vaginal mass. Partial resection, intracavitary fluid drainage and mucosal lining curettage had been made in the previous laparotomy. Computed tomography (CT) and perioperative gross appearance revealed a large vaginal cyst extended into the pelvic canal that was adhering to the bladder trigone, both ureters, the urethra and the descending colon. The mass was resected completely. The dog recovered uneventfully. To the author’s knowledge, this is the first report of a canine intra-abdominal vaginal mass that was preoperatively evaluated using CT and the histological result was most consistent …
Necrotic Lung Tumor Mimicking Primary Pulmonary Abscess On Computed Tomographic Imaging Study In A Dyspneic Dog, Mihyun Choi, Namsoon Lee
Necrotic Lung Tumor Mimicking Primary Pulmonary Abscess On Computed Tomographic Imaging Study In A Dyspneic Dog, Mihyun Choi, Namsoon Lee
The Thai Journal of Veterinary Medicine
A 14-year-old spayed female Shih-Tzu dog was evaluated for a 1-month history of progressive coughing. Results of the complete blood count and serum biochemistry panel indicated inflammation. Thoracic radiography showed pleural effusion, and cytology revealed septic pyothorax. After antibiotics medication, the patient improved clinical signs but relapsed pleural effusion with a suspicious lung lesion. Computed tomography (CT) of the thorax showed a cavitary lesion with ring-enhanced irregular walls and poorly defined margins in the left cranial lung lobe. The main differential diagnosis considered was lung abscess, but the histopathological diagnosis was necrotic lung adenocarcinoma. This case suggests that both a …
Cervical Lymphangiosarcoma In A Poodle Dog: Surgical Treatment And Chemotherapy, Minkyung Kim, Young-Hwan Kim, Jae-Eun Hyun
Cervical Lymphangiosarcoma In A Poodle Dog: Surgical Treatment And Chemotherapy, Minkyung Kim, Young-Hwan Kim, Jae-Eun Hyun
The Thai Journal of Veterinary Medicine
A 7-year-old neutered male Poodle exhibited a persistent caudoventral cervical mass with draining lesions characterized by chronic and relapsing features. Upon presentation, the mass measured 7 × 11 × 11.5 cm, containing sanguine fluid. Computed tomography revealed the diffuse extension of the cervical mass from the C3 level to the thoracic inlet, affecting the sternal lymph node. Extensive surgical removal was attempted with meticulous resection to avoid damaging the right jugular vein, carotid sheath, and vagus nerve within the mass. Histopathology and immunohistochemical staining for factor VIII confirmed the diagnosis of lymphangiosarcoma. Due to inadequate surgical margin excision, four cycles …
Intraluminal Tracheal Stenting In Dog With Tracheal Collapse : A Case Report, Ratiporn Tantisak, Siriluck Luckanahasaporn, Ardong Atiptamvaree, Tamolwan Anyamaneecharoen, Kamonchanok Lamsaman, Suphat Soeratanapant, Poondej Charunmethee
Intraluminal Tracheal Stenting In Dog With Tracheal Collapse : A Case Report, Ratiporn Tantisak, Siriluck Luckanahasaporn, Ardong Atiptamvaree, Tamolwan Anyamaneecharoen, Kamonchanok Lamsaman, Suphat Soeratanapant, Poondej Charunmethee
The Thai Journal of Veterinary Medicine
A 12-year-old female neutered dog was referring to the pet hospital for the chief complaint of syncopic episodes 3 times/day. The dog had history of severe goose-honking non-productive cough and tachypnea. The dog got worsen despites medical management was consist of antibiotic, mucolytic, bronchodilator, glucocorticoids and nebulization. The dog was not response to medication then develop to apnea due to obstructive breathing. The radiographs diagnosis from private clinic was redundant trachea with narrowing intrathoracic trachea. The surgical treatment was considered. The tracheobronchoscopy was confirmed Tracheal collapse at mid cervical to cranial thoracic part. Stenting was a treatment options in life-threatening …
Impacts Of Species, Gender Disparities, And Covid-19 Lockdowns On Population Control: Insights From 337,590 Dogs And Cats In Bangkok Metropolitan Administration (Bma), Thailand (2009-2023), Shanaporn Leelakajornkit, Natchanon Dumniem, Permsak Wataganara, Siwa Maison, Suppawiwat Ponglowhapan
Impacts Of Species, Gender Disparities, And Covid-19 Lockdowns On Population Control: Insights From 337,590 Dogs And Cats In Bangkok Metropolitan Administration (Bma), Thailand (2009-2023), Shanaporn Leelakajornkit, Natchanon Dumniem, Permsak Wataganara, Siwa Maison, Suppawiwat Ponglowhapan
The Thai Journal of Veterinary Medicine
Surgical sterilization stands as a key solution to address the overpopulation of dogs and cats, with numerous influencing factors impacting the success of population control efforts, including species, gender, and financial conditions. The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, in 2020 has significantly altered human life and impacted pet animals. Lockdown restrictions were implemented in various countries, including Thailand, affecting the cumulative data of neutered animals, which was subsequently analyzed in this study. There were 337,590 dogs and cats from 2009 to 2023, and the data were systematically categorized by years, species, and gender. …
Biomechanical Comparison Of Transosseous Four-Strand Tendon Suture Patterns For Repair Of Ruptured Distal Common Calcaneal Tendon: An Ex Vivo Study In Dogs, Tae-Hwan Ahn, Min-Yeong Lee, Jaekyoung Lee, Hwi-Yool Kim
Biomechanical Comparison Of Transosseous Four-Strand Tendon Suture Patterns For Repair Of Ruptured Distal Common Calcaneal Tendon: An Ex Vivo Study In Dogs, Tae-Hwan Ahn, Min-Yeong Lee, Jaekyoung Lee, Hwi-Yool Kim
The Thai Journal of Veterinary Medicine
There is no golden standard method of suturing for distal common calcaneal tendon rupture in dogs. Thus this study aimed to evaluate and compare the mechanical characteristics of three distinct transosseous suture (TOS) repair techniques, which were specifically developed to treat ruptured distal common calcaneal tendons and to identify golden standard suturing method. The study was performed using 30 hind limbs obtained from 15 canine cadavers with weights ranging between 7.9 kg and 11.4 kg. The repair methods using modified Becker suture (group 1), modified Krackow suture (group 2), and modified double-Tsuge suture (group 3) were randomly assigned. Each group …
Normal Thymus Evaluation Using Radiographs And Computed Tomographic Images In Young And Adult Dogs, Yoenhee Park, Sang-Kwon Lee, Sooyoung Choi, Hojung Choi, Youngwon Lee, Kija Lee
Normal Thymus Evaluation Using Radiographs And Computed Tomographic Images In Young And Adult Dogs, Yoenhee Park, Sang-Kwon Lee, Sooyoung Choi, Hojung Choi, Youngwon Lee, Kija Lee
The Thai Journal of Veterinary Medicine
The thymus generally presents as a sail-shaped soft-tissue opacity on thoracic radiographs in young, pre-pubescent dogs. After puberty, lymphatic tissue is replaced by adipose tissue and can usually no longer be identified on radiographs; however, thymic remnants have often been observed in adult dogs. The objective of this retrospective descriptive study was to investigate the incidence of thymic remnants using thoracic radiographs and to analyze the incidence in dogs by age, sex and breed. We analyzed the data from 1,464 dogs that underwent both thoracic ventrodorsal and right lateral radiography, of which 40 underwent both radiography and computed tomography (CT). …
Physiological And Behavioral Stress-Induced Responses Of Dogs During Veterinary Examinations, Jessica Ellen Vester
Physiological And Behavioral Stress-Induced Responses Of Dogs During Veterinary Examinations, Jessica Ellen Vester
Honors Projects
This study investigated whether stress responsiveness in dogs is more significant when the owner is present or absent during a veterinary examination. The study consisted of two experimental groups: "owner absent" and "owner present." Both groups consisted of 25 dogs each, totaling 50 dogs observed. A veterinarian and veterinary assistant recorded the dog's behavioral and physiological stress responses. Each group's behavioral and physiological stress-induced responses were compared using a Fischer Exact test and an Analysis of Covariance. The findings showed that dogs whose owners are present during the veterinary examination display fewer stress responses than dogs whose owners are absent …
Ex Vivo Biomechanical Evaluation Of A Novel Screw For Tibial Plateau Leveling Osteotomy, William Seth Kettleman
Ex Vivo Biomechanical Evaluation Of A Novel Screw For Tibial Plateau Leveling Osteotomy, William Seth Kettleman
Theses and Dissertations
Twelve pairs of cadaveric pelvic limbs were harvested from skeletally mature dogs. Tibias were randomly assigned pairwise to two study groups: locking buttress screw fixation (LBS) and bone-screw-fastener fixation (BSF). A tibial plateau leveling osteotomy (TPLO) was performed. Each specimen was positioned in a servohydraulic testing machine to simulate physiological orientation and loading at the mid-point of the stance phase at the walk. Cyclic loading was performed for 30,000 cycles at 4Hz with a peak-load of 1000N. The cyclic test was then continued by stepwise increasing the peak-load at a rate of 75N per 500 cycles until failure of the …
Evaluation Of Residual Antibacterial Effects On Canine Skin Surface And Hairs Following Treatment With Five Commercial Mousse Products Against Staphylococcus Pseudintermedius In Vitro, Chi-Yen Wu
LSU Master's Theses
Topical products are essential treatments for canine superficial bacterial folliculitis. However, studies for commercial products typically evaluate antibacterial effects on hairs rather than the skin surface. In addition, the interference from the hair length has not been evaluated in these studies. Therefore, the study objective for this study was to evaluate the residual antibacterial effects of five mousse products, (1) 2% chlorhexidine and 2% miconazole, (2) 0.05% phytosphingosine, (3) 2% salicylic acid and 10% ethyl lactate, (4) 3% chlorhexidine and 0.5% climbazole, and (5) 2% chlorhexidine and 1% ketoconazole on both the skin surface and hairs in both short- and …
Canine Dystocia In 50 Uk First-Opinion Emergency Care Veterinary Practices: Clinical Management And Outcomes, Dan G. O'Neill, Aoife M. O'Sullivan, Erin A. Manson, David B. Church, Paul Mcgreevy, Amanda K. Boag, Dave C. Brodbelt
Canine Dystocia In 50 Uk First-Opinion Emergency Care Veterinary Practices: Clinical Management And Outcomes, Dan G. O'Neill, Aoife M. O'Sullivan, Erin A. Manson, David B. Church, Paul Mcgreevy, Amanda K. Boag, Dave C. Brodbelt
Natology Collection
Canine dystocia is a relatively common veterinary presentation. First opinion emergency care clinical data from 50 Vets Now clinics across the UK were used to explore dystocia management and outcomes in bitches. Caesarean section (CS) was performed on 341/701 (48.6 per cent (95 per cent CI 44.9 to 52.4)) of dystocia cases. The bulldog (OR 7.60, 95 per cent CI 1.51 to 38.26, P=0.014), Border terrier (OR 4.89, 95 per cent CI 0.92 to 25.97, P=0.063) and golden retriever (OR 4.07, 95 per cent CI 0.97 to 17.07, P=0.055) had the highest odds of CS among dystocic bitches compared with …
Evaluation Of A Nutraceutical Flex Choice For Anti-Arthritic Efficacy And Safety In Moderately Osteoarthritic Dogs, Rachael E. Webber
Evaluation Of A Nutraceutical Flex Choice For Anti-Arthritic Efficacy And Safety In Moderately Osteoarthritic Dogs, Rachael E. Webber
Murray State Theses and Dissertations
Arthritis is a very common chronic debilitating disease in people and dogs alike. It does not discriminate based on species, and one in five dogs suffer from osteoarthritis. The purpose of this study was to evaluate the safety and anti-arthritic efficacy of a nutraceutical, Flex Choice, in moderately arthritic canines. Five moderately arthritic canines that weighed between 40-65 pounds were selected for this study. Moderate arthritis was considered a ranking of 4-6 on a scale of 1-10 with 1 being no/minimal pain and 10 being severe and constant pain. All five canines were orally administered one Flex Choice soft chew …
Development Of A Novel In Vivo Corneal Fibrosis Model In The Dog, K. M. Gronkiewicz, Elizabeth A. Giuliano, K. Kuroki, F. Bunyak, Ajay Sharma, L. B. C. Teixeira, C. W. Hamm, R. R. Mohan
Development Of A Novel In Vivo Corneal Fibrosis Model In The Dog, K. M. Gronkiewicz, Elizabeth A. Giuliano, K. Kuroki, F. Bunyak, Ajay Sharma, L. B. C. Teixeira, C. W. Hamm, R. R. Mohan
Pharmacy Faculty Articles and Research
The aim of this study was to develop a novel in vivo corneal model of fibrosis in dogs utilizing alkali burn and determine the ability of suberanilohydroxamic acid (SAHA) to inhibit corneal fibrosis using this large animal model. To accomplish this, we used seven research Beagle dogs. An axial corneal alkali burn in dogs was created using 1 N NaOH topically. Six dogs were randomly and equally assigned into 2 groups: A) vehicle (DMSO, 2 μL/mL); B) anti-fibrotic treatment (50 μM SAHA). The degree of corneal opacity, ocular health, and anti-fibrotic effects of SAHA were determined utilizing the Fantes grading …