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Full-Text Articles in Veterinary Medicine

Cloning And Expression Of Bacteriophage T4 Lysozyme Gene (Gene E) In Escherichia Coli Via Pcr Amplification, Ali̇ İrfan Güzel, Numan Özcan, Hali̇l Kasap Jan 2002

Cloning And Expression Of Bacteriophage T4 Lysozyme Gene (Gene E) In Escherichia Coli Via Pcr Amplification, Ali̇ İrfan Güzel, Numan Özcan, Hali̇l Kasap

Turkish Journal of Veterinary & Animal Sciences

Lysozyme (EC 3.2.1.17) is an enzyme that catalyzes the hydrolysis of \beta(1-->4) glycosidic bonds between N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM), which are present in peptidoglycan heteropolymers of the prokaryotic cell wall. The purpose of this study was the cloning and expression of the bacteriophage T4 lysozyme gene (gene e) via PCR amplification in Escherichia coli using the pUC18 and pRS416 vectors. PCR amplification is carried out by using the primers having Bam HI recognition sites at their 5' ends. After digesting the vectors and PCR product with Bam HI endonuclease, two recombinant plasmids were constructed by ligation reaction …


Detection And Rflp Analysis Of Canine Parvovirus (Cpv) Dna By Polymerase Chain Reaction (Pcr) In A Dog, Aykut Özkul, İhsan Keleş, Taner Karaoğlu, Mehmet Çabalar, İbrahi̇m Burgu Jan 2002

Detection And Rflp Analysis Of Canine Parvovirus (Cpv) Dna By Polymerase Chain Reaction (Pcr) In A Dog, Aykut Özkul, İhsan Keleş, Taner Karaoğlu, Mehmet Çabalar, İbrahi̇m Burgu

Turkish Journal of Veterinary & Animal Sciences

In this study, the detection of canine parvovirus (CPV) in a fecal sample from a dog with enteritis was performed for the first time using the polymerase chain reaction (PCR) in Turkey. The final PCR product was analyzed using the restriction fragment length polymorphysm (RFLP) technique. RFLP analysis using Apa LI and Eco RV restriction endonucleases revealed homology in the nucleotide sequence in at least the VP2 coding region of the virus DNAs detected in the fecal specimen and prepared from attenuated vaccine virus as a positive control.


Detection Of Leptospira Species By Polymerase Chain Reaction (Pcr) In Urine Of Cattle, Burhan Çeti̇nkaya, Hasan Basri̇ Ertaş, Hasan Öngör, Adi̇le Muz Jan 2000

Detection Of Leptospira Species By Polymerase Chain Reaction (Pcr) In Urine Of Cattle, Burhan Çeti̇nkaya, Hasan Basri̇ Ertaş, Hasan Öngör, Adi̇le Muz

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to investigate the prevalance of leptospirosis in the urine of cattle slaughtered in three major abattoirs in the east of Turkey. A polymerase chain reaction (PCR) based on a pair of genus-specific primers was used to detect leptospiral DNA in the urine samples of 473 cattle, 284 of which were from Elazig, 112 from Malatya and 77 from Diyarbakir. The detection limit of the method was determined to be approximately five bacteria per ml of urine. In the examination of urine samples, 4.02% (19/473) (95% confidence intervals [Cl] 2.4-6.2) were found to be positive by …