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The Thai Journal of Veterinary Medicine

2010

Rat

Articles 1 - 3 of 3

Full-Text Articles in Veterinary Medicine

Chronic Toxicity Study Of Kaempferia Parviflora Wall Ex. Extract, Songpol Chivapat, Pranee Chavalittumrong, Aimmanas Attawish, Anudep Rungsipipat Dec 2010

Chronic Toxicity Study Of Kaempferia Parviflora Wall Ex. Extract, Songpol Chivapat, Pranee Chavalittumrong, Aimmanas Attawish, Anudep Rungsipipat

The Thai Journal of Veterinary Medicine

K. parviflora is a medicinal plant possessing high potential for development of various health products. The objective of this chronic toxicity study was to investigate the safety of ethanolic extract of chronic Kaempferia parviflora Wall ex Bak in Wistar rats. The animals were randomly divided into five groups, twenty four rats each (12 males and 12 females). Three treatment groups were orally administered with K. parviflora extract at doses of 5, 50 and 500 mg/kg/day for six months respectively, which were equivalent to 1, 10 and 100 times of human use, while two control groups were orally given with distilled …


The Efficacy Of Pure Natural Repellents On Rat Responses Using Circular Open Field, Sarinee Kalandakanond-Thongsong, Suwaporn Daendee, Boonrit Thongsong, Vivat Chavananikul Dec 2010

The Efficacy Of Pure Natural Repellents On Rat Responses Using Circular Open Field, Sarinee Kalandakanond-Thongsong, Suwaporn Daendee, Boonrit Thongsong, Vivat Chavananikul

The Thai Journal of Veterinary Medicine

Rodent infestation is considered as one of the major pest problems since it is not only acting as a health hazard, but also causes damages to household, agricultural fields and even transportation business. The use of rodenticides is a common approach to rodent control, however, most rodenticides are poisonous to man. Therefore, using natural extracts as a rat repellent may be a better alternative. In the current study, various natural extracts were experimented whether they could repel a rat when testing in the behavioral model, a circular open field. The tested substances were wintergreen oil, chilli, peppermint oil, bergamot oil …


Toxicity Testing Of Flowers Of Neem Tree (Azadirachta Indica A. Juss), Piengchai Kupradinun, Anong Tepsuwan, Nopsarun Tanthasri, Nuntana Meesiripan, Sirirat Tunsakul, Warayupa Tompat, Yaninee Jarratwisarutporn, Wannee R. Kusamran Mar 2010

Toxicity Testing Of Flowers Of Neem Tree (Azadirachta Indica A. Juss), Piengchai Kupradinun, Anong Tepsuwan, Nopsarun Tanthasri, Nuntana Meesiripan, Sirirat Tunsakul, Warayupa Tompat, Yaninee Jarratwisarutporn, Wannee R. Kusamran

The Thai Journal of Veterinary Medicine

Flowers of neem (Azadirachta indica A. Juss) possess a strong cancer chemopreventive potential in rats as well as antimicronucleus formation in mice. However, toxicity testing has never been evaluated. This study was aimed to determine its acute and subacute toxicities in Wistar rats. Acute toxicity was conducted by feeding methanol extract of neem flowers (MENF) suspending in 20% propylene glycol at 6, 9 and 12 g/kg bw. On the other hand, subacute toxicity testing was carried out by feeding MENF suspending in 0.5% tragacanth at 150, 750 and 1,500 mg/kg bw for 90 consecutive days. Hematology, blood chemistry and histopathology …