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Articles 61 - 90 of 2797
Full-Text Articles in Veterinary Medicine
Extended-Release Buprenorphine With Bupivacaine Effectively Provides Postoperative Analgesia In A Mouse Laparotomy Model, Monika K. Huss, Amber Kerk, Renee Cotton, Helen Chum, Michael Hsieh, Katechan Jampachaisri, Patrick Sharp, Cholowat Pacharinsak
Extended-Release Buprenorphine With Bupivacaine Effectively Provides Postoperative Analgesia In A Mouse Laparotomy Model, Monika K. Huss, Amber Kerk, Renee Cotton, Helen Chum, Michael Hsieh, Katechan Jampachaisri, Patrick Sharp, Cholowat Pacharinsak
The Thai Journal of Veterinary Medicine
Multimodal analgesia is widely encouraged for major survival surgery. This facilitates lower doses of individual drugs, thereby reducing side effects. Extended-release analgesics offer sustained analgesia coverage, prevent drug dosing nadirs, and reduce stress. Studies evaluating multimodal and extended-release analgesia combinations for major survival surgery in mice are limited. We compared the analgesic effect of bupivacaine and extended-release buprenorphine (Bupi-ER) to bupivacaine and buprenorphine HCl (Bupi-HCl). We hypothesized that preoperative Bupi-ER would provide more effective analgesia than Bupi-HCl. Mice were randomly assigned to 1 of 2 treatment groups: bupivacaine (2 mg/kg, local infiltration, once) with either 1) extended-release buprenorphine (0.6 mg/kg, …
Antimicrobial Susceptibility Profiles (Mic And Mmc) Against Mycoplasma Gallisepticum And M. Synoviae Isolated From Chicken Farms In Thailand, Kriengwich Limpavithayakul, Alongkorn Amonsin, Nataya Charoenvisal, Arithat Limsatanun, Katanyu Yangsuk, Sumrit Toopiya, Füsun Güngör, Esther Schonewille, Javier Uriarte, Somsak Pakpinyo
Antimicrobial Susceptibility Profiles (Mic And Mmc) Against Mycoplasma Gallisepticum And M. Synoviae Isolated From Chicken Farms In Thailand, Kriengwich Limpavithayakul, Alongkorn Amonsin, Nataya Charoenvisal, Arithat Limsatanun, Katanyu Yangsuk, Sumrit Toopiya, Füsun Güngör, Esther Schonewille, Javier Uriarte, Somsak Pakpinyo
The Thai Journal of Veterinary Medicine
Mycoplasma gallisepticum (MG) and M. synoviae (MS) are important pathogens causing significant economic losses in poultry production. Disease prevention and control strategies include vaccination, antimicrobial therapy, and strict biosecurity measures. The present study provides, for the first time, both minimum inhibitory concentration (MIC) and minimum mycoplasmacidal concentration (MMC) values as antimicrobial susceptibility profiles of Thai MG and MS field isolates. This study aimed to evaluate the susceptibility of five MG and ten MS isolates to various antimycoplasma drugs: doxycycline, lincomycin-spectinomycin, tiamulin, tilmicosin, tylosin, and tylvalosin, using a microdilution broth assay. For MG isolates, tilmicosin had the highest mean MIC (12.5 …
Prevalence And Risk Factors Of Concurrent Osteoarthritis And Urolithiasis In Dogs In Thailand (2018–2020), Faiz Ihsanul Kamil, Kumpanart Soontornvipart
Prevalence And Risk Factors Of Concurrent Osteoarthritis And Urolithiasis In Dogs In Thailand (2018–2020), Faiz Ihsanul Kamil, Kumpanart Soontornvipart
The Thai Journal of Veterinary Medicine
Osteoarthritis is a degenerative joint disease that significantly impacts dog health, often leading to chronic pain, reduced mobility, and behavioral changes that may predispose dogs to secondary conditions such as urolithiasis. This study aimed to investigate the association between osteoarthritis and urolithiasis in dogs using radiographic imaging data collected from the Small Animal Teaching Hospital, Chulalongkorn University, Thailand, over a three-year period (January 2018 to December 2020). A total of 16,377 dogs were included, and cases of osteoarthritis, urolithiasis, or the concurrent occurrence of both conditions were identified through a systematic database review. Binary logistic regression models were used to …
Monitoring Of African Horse Sickness Virus-Specific Antibodies In Horses, Northeastern Thailand, Napawan Bunpapong, Kitikhun Udom, Ekkapat Chamsai, Patchara Phuektes, Suphattra Jittimanee, Suphannika Phutthachalee, Supassama Chaiyawong, Kamonpan Charoenkul, Alongkorn Amonsin Prof. Dr.
Monitoring Of African Horse Sickness Virus-Specific Antibodies In Horses, Northeastern Thailand, Napawan Bunpapong, Kitikhun Udom, Ekkapat Chamsai, Patchara Phuektes, Suphattra Jittimanee, Suphannika Phutthachalee, Supassama Chaiyawong, Kamonpan Charoenkul, Alongkorn Amonsin Prof. Dr.
The Thai Journal of Veterinary Medicine
African horse sickness (AHS) is caused by infection with the African horse sickness virus (AHSV). In March 2020, AHS was first reported in Thailand due to the importation of subclinically infected host animals, such as zebras. In this study, we conducted a serological survey for AHSV-specific antibodies across 21 horse farms in the northeastern provinces (n=3) of Thailand. A total of 600 serum samples were collected for cross-sectional (n = 292) and longitudinal serological monitoring (n = 308). A cross-sectional study was conducted in 2020, during which serum samples (n = 292) were collected and tested for AHS antibodies using …
Effects Of 25-Hydroxyvitamin D₃ Supplementation As A Partial Replacement For Vitamin D₃ On Laying Performance, Egg Quality, And Bone Traits In Late-Stage Laying Hens, Morakot Nuntapaitoon, Nan Choisunirachon, Somporn Techangvamsuwan, Jiramate Jittidecha
Effects Of 25-Hydroxyvitamin D₃ Supplementation As A Partial Replacement For Vitamin D₃ On Laying Performance, Egg Quality, And Bone Traits In Late-Stage Laying Hens, Morakot Nuntapaitoon, Nan Choisunirachon, Somporn Techangvamsuwan, Jiramate Jittidecha
The Thai Journal of Veterinary Medicine
The objective of this study was to assess the impact of dietary 25-hydroxy vitamin D3 (25OHD3) supplementation during the late laying hens on egg quality, hen performance and bone computerized tomography (CT) scanning parameters. In total, 24,862 Hy-Line Brownmax hens of 61 weeks old were randomly divided into two groups: the control group (n = 12,368) received a diet containing vitamin D3 at 3,000 IU/kg, and the treatment group (n = 12,494) received a diet containing vitamin D3 at 1,500 IU/kg and 25OHD3 at 1,500 IU/kg. The dietary intervention from 61 weeks of age to …
Genetic Characterization Of Lpai-H4n2 And H4n8 Viruses Recovered From Free-Grazing Ducks In Thailand, Supanat Boonyapisitsopa, Supassama Chaiyawong, Kamonpan Charoenkul, Kitikhun Udom, Ekkapat Chamsai, Napawan Bunpapong, Somsak Pakpinyo, Alongkorn Amonsin Prof. Dr.
Genetic Characterization Of Lpai-H4n2 And H4n8 Viruses Recovered From Free-Grazing Ducks In Thailand, Supanat Boonyapisitsopa, Supassama Chaiyawong, Kamonpan Charoenkul, Kitikhun Udom, Ekkapat Chamsai, Napawan Bunpapong, Somsak Pakpinyo, Alongkorn Amonsin Prof. Dr.
The Thai Journal of Veterinary Medicine
nfluenza A viruses (IAVs) can infect birds and various mammals. In this study, we retrospectively isolated and characterized IAVs (n=8) from oropharyngeal and cloacal swab samples of free-grazing ducks collected during December 2018 to December 2021, by using egg inoculation and whole-genome sequencing. The IAVs could be subtyped as IAV-H4N2 (n = 3) and IAV-H4N8 (n = 5) using real-time RT-PCR assays. Genetic and phylogenetic analyses revealed that all eight genes of Thai IAV-H4 belong to the Avian Eurasian lineage. Both Thai IAV-H4N2 and IAV-H4N8 exhibited low pathogenic avian influenza (LPAI) characteristics and were susceptible to oseltamivir and amantadine. This …
Prevalence, Antimicrobial Resistance Characteristics And Virulence Genes Of Streptococcus Suis In Pigs In Upper Northern Thailand, Wanida Mala, Rangsiya Prathan, Si Thu Hein, Sunpetch Angkittitrakul, Asinamai Athliamai Bitrus, Rungtip Chuanchuen
Prevalence, Antimicrobial Resistance Characteristics And Virulence Genes Of Streptococcus Suis In Pigs In Upper Northern Thailand, Wanida Mala, Rangsiya Prathan, Si Thu Hein, Sunpetch Angkittitrakul, Asinamai Athliamai Bitrus, Rungtip Chuanchuen
The Thai Journal of Veterinary Medicine
This study aimed to investigate the prevalence, virulence genes and antimicrobial resistance of Streptococcus suis from pigs in Upper-Northern Thailand. A total of 768 nasal swabs were obtained from pigs at the municipal slaughterhouses in five provinces including Phayao (n=202), Nan (n=190), Chiang Rai (180), Chiang Mai (n=130), and Mae Hong Son (n=66) in 2018-2019. The prevalence of S. suis varied from 3.0%-9.4%, of which the highest prevalence was in Chiang Rai (9.4%) and Mae Hong Son (9.1%). Of all 59 isolates confirmed to be S. suis, serotype 8 (50.8%) was most commonly identified, followed by serotype 10 (3.4%), …
Effect Of Post-Operative Clothing, Bandage, And Collar Application On Stress After Ovariohysterectomy In Cats, Çağatay Esin, Seba Raouf, Gülşah Saral, Büşra Uzun
Effect Of Post-Operative Clothing, Bandage, And Collar Application On Stress After Ovariohysterectomy In Cats, Çağatay Esin, Seba Raouf, Gülşah Saral, Büşra Uzun
The Thai Journal of Veterinary Medicine
Ovariohysterectomy is a common surgical procedure in veterinary medicine, not only for reproductive control but also for conditions like pyometra, metritis, mammary tumors, and other reproductive disorders. Pain in cats occurs as a response of the body and is accompanied by various physiological and behavioral changes. Pain in cats, though prevalent, is often under-recognized and inadequately treated. The Glasgow pain scale is a psychometrically designed tool for assessing acute pain in veterinary patients. Serotonin (5-HT), a biogenic monoamine derived from tryptophan, functions as a mood-regulating neurotransmitter and may decrease following surgical interventions. This study aimed to evaluate post-operative pain and …
Assessing The Efficacy Of Eutectic Mixture Of Local Anesthesia Cream And Vapocoolant Spray In Mitigating The Pain Associated With Ear-Tagging In Pre-Weaned Calves, Yu-Jhe Lo, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan
Assessing The Efficacy Of Eutectic Mixture Of Local Anesthesia Cream And Vapocoolant Spray In Mitigating The Pain Associated With Ear-Tagging In Pre-Weaned Calves, Yu-Jhe Lo, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan
The Thai Journal of Veterinary Medicine
This study evaluated the efficacy of a eutectic mixture of local anesthetics (EMLA) cream and vapocoolant spray (VS) in preventing pain in calves following ear-tagging. Thirty-four calves were randomly assigned to three groups: no anesthesia control (CON, n=11), EMLA applied 60 minutes prior (EMLA, n=11), and five-second VS application immediately prior (VS, n=12). Pain pressure threshold (PPT) was measured at 18±1 days of age, with the left ear of the CON group serving as the sham group (Sham, n=11), followed by ear-tagging at 21±1 days. Post-tagging assessments included pain-related behaviors, serum cortisol levels, heart rate, and wound scores. The PPT …
Ultrasound-Guided Sciatic And Femoral Nerve Block For Perioperative Pain Management In A Thai Crossbreed Dog Undergoing Tibial Plateau Leveling Osteotomy (Tplo): A Case Report, Wutti Bunjerdsuwan, Sirirat Niyom
Ultrasound-Guided Sciatic And Femoral Nerve Block For Perioperative Pain Management In A Thai Crossbreed Dog Undergoing Tibial Plateau Leveling Osteotomy (Tplo): A Case Report, Wutti Bunjerdsuwan, Sirirat Niyom
The Thai Journal of Veterinary Medicine
This case report presents the use of ultrasound-guided sciatic and femoral nerve blocks as an alternative analgesic technique for perioperative pain control in a Thai crossbreed dog undergoing left tibial plateau leveling osteotomy (TPLO). The orthopedic examination revealed a 4/5 left hindlimb lameness score, with positive results on both the tibial compression test (TCT) and cranial drawer test (CDT). Radiographic evaluation showed the absence of a fat pad sign and osteophyte formation around the left stifle joint. A definitive diagnosis of left cranial cruciate ligament rupture (CCLR) was made. The dog underwent CCLR correction via TPLO, with perioperative pain managed …
Diagnostic Imaging Of A Large Pancreatic Pseudocyst With Infection Over Time In A Dog, Chanyoung Ryu, Wooseok Jin, Sang-Kwon Lee, Daji Noh, Sooyoung Choi, Kija Lee
Diagnostic Imaging Of A Large Pancreatic Pseudocyst With Infection Over Time In A Dog, Chanyoung Ryu, Wooseok Jin, Sang-Kwon Lee, Daji Noh, Sooyoung Choi, Kija Lee
The Thai Journal of Veterinary Medicine
A 5-year-old Pompitz presented with anorexia and vomiting. Radiographs showed a half-moon-shaped mass in the left cranial abdomen. A large cyst was identified near the left pancreas on ultrasound. Computed tomography revealed a fluid-attenuating mass with rim enhancement in the pancreas. Laboratory tests identified Staphylococcus warneri in the cystic lesion, and pancreatic pseudocyst with infection was suspected. The fluid accumulation and clinical signs recurred over several months. Pre-operative magnetic resonance imaging showed a hyperintense cystic lesion with a duct-like structure and hyperintense line between the cyst and the gastric wall on T2-weighted images as well as signal change of the …
Assessment Of The Relationship Between Particulate Matter Level And Respiratory Diseases In Dogs And Cats In Bangkok, Thailand, Nattawan Tangmahakul, Janenisa Klomklao, Damisa Thanyapornsombat, Tuangphon Lertsubkhajohn, Wiphawa Piboonlapudom, Satraporn Mettaviparee, Sirilak Disatian Surachetpong
Assessment Of The Relationship Between Particulate Matter Level And Respiratory Diseases In Dogs And Cats In Bangkok, Thailand, Nattawan Tangmahakul, Janenisa Klomklao, Damisa Thanyapornsombat, Tuangphon Lertsubkhajohn, Wiphawa Piboonlapudom, Satraporn Mettaviparee, Sirilak Disatian Surachetpong
The Thai Journal of Veterinary Medicine
Particulate matter (PM) 2.5 has become a serious pollution concern in many countries, including Thailand. Due to its small particle size, PM2.5 can penetrate deep into pulmonary tissues, posing health risks to humans. Furthermore, it is hypothesized that PM2.5 may also cause respiratory diseases in dogs and cats. This study aimed to evaluate a relationship between PM2.5 levels and the number of dogs and cats visiting due to respiratory problems in Bangkok, Thailand, and to investigate potential environmental factors that may contribute to these health outcomes. A total of 184 dogs and 73 cats were included in the study. Medical …
Impact Of Colostrum Lactose Concentration In Relation To Metabolomic Profiles On Kid Growth Performance Of Black Bengal Goats, Tien Thi Phuong Vo, Chollada Buranakarl, Sumonwan Chamsuwan, Sumpun Thammacharoen, Morakot Nuntapaitoon, Sarn Settachaimongkon
Impact Of Colostrum Lactose Concentration In Relation To Metabolomic Profiles On Kid Growth Performance Of Black Bengal Goats, Tien Thi Phuong Vo, Chollada Buranakarl, Sumonwan Chamsuwan, Sumpun Thammacharoen, Morakot Nuntapaitoon, Sarn Settachaimongkon
The Thai Journal of Veterinary Medicine
Colostrum composition, including lactose concentration in relation to metabolomic profiles on kids’ growth performance of Black Bengal goats, has not yet been elucidated. Macronutrients, including lactose and metabolomic profiles, were determined in 37 colostrum samples using MilkoScan and 1H-nuclear magnetic resonance technique, respectively. Kids’ growth performance, including birth weight, average daily gain at 0–4 weeks (ADG0-4W), 4–8 weeks (ADG4-8W), and wean weight were determined. A total of 51 metabolites were detected in the colostrum. From the general linear model for univariate analysis, kids born from multiple litter sizes showed lower ADG during the first month postpartum (P = 0.004). …
Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna
Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna
The Thai Journal of Veterinary Medicine
New Zealand green-lipped mussel (Perna canaliculus) is a shellfish with a green shell containing many types of fatty acids, especially polyunsaturated fatty acids (PUFAs). The aim of the present study was to investigate the safety of dietary PUFAs supplementation on blood hematology, chemistry and coagulogram pancreatic enzymes in dogs and cats. Twelve healthy beagle dogs and healthy mature cats were used in these studies. Complete randomized block and triplicate 4×4 Latin square designs were used for these dog and cat safety studies, respectively. Experimental diets composed of sham control (0X) and 3 treatment groups, including 1X, 3X, and …
Region-Specific Hematological And Biochemical Reference Intervals For Southern Thai Fighting Bulls, Dhiravit Chantip, Nantaporn Chooruang, Kitikarn Sakuna, Niramol Thongtem, Wiruntita Bohman
Region-Specific Hematological And Biochemical Reference Intervals For Southern Thai Fighting Bulls, Dhiravit Chantip, Nantaporn Chooruang, Kitikarn Sakuna, Niramol Thongtem, Wiruntita Bohman
The Thai Journal of Veterinary Medicine
Accurate health assessments are vital for the performance and welfare of fighting bulls. Existing hematological and biochemical reference intervals (RIs) for cattle may not adequately reflect the unique characteristics of fighting bulls due to breed, age, and geographical differences. This study aimed to develop and apply region-specific RIs for hematological and biochemical parameters in fighting bulls from southern Thailand. A retrospective analysis of laboratory records was conducted on 1,460 healthy fighting bulls enrolled in an annual health check program at the Livestock Animal Hospital, Faculty of Veterinary Sciences, Rajamangala University of Technology Srivijaya, from January 2016 to December 2023. Blood …
Effect Of Feeding A Saccharomyces Cerevisiae Fermentation Product On Immune Response To Vaccines Against Newcastle Disease Virus, Avian Influenza Virus, And The Prevalence Of Chronic Respiratory Disease And Coccidiosis In Chickens Raised In A Low Biosecurity Production System, Bui Thi Hien, Ho Thi Dung, Pham Hoang Son Hung, Le Duc Thao, Nguyen Van Chao, Tran Quang Vui, Nguyen Thi Hoa, Anjan Mondal, Nsereko Victor, Le Dinh Phung
Effect Of Feeding A Saccharomyces Cerevisiae Fermentation Product On Immune Response To Vaccines Against Newcastle Disease Virus, Avian Influenza Virus, And The Prevalence Of Chronic Respiratory Disease And Coccidiosis In Chickens Raised In A Low Biosecurity Production System, Bui Thi Hien, Ho Thi Dung, Pham Hoang Son Hung, Le Duc Thao, Nguyen Van Chao, Tran Quang Vui, Nguyen Thi Hoa, Anjan Mondal, Nsereko Victor, Le Dinh Phung
The Thai Journal of Veterinary Medicine
This study was carried out in a low biosecurity production system to explore the effects of a Saccharomyces cerevisiae fermentation product (SCFP) on immune responses to vaccination against Newcastle disease virus (NDV) and Avian influenza (H5N1) and prevalence of common diseases in chickens including chronic respiratory disease (CRD) and coccidiosis. One hundred and ninety two 1-day-old chickens were randomly assigned into control (a standard basal diet) and treatment (a standard basal diet containing 1.25 kg/MT of Diamond V XPC™ – a Saccharomyces cerevisiae fermentation product). Immunity data on antibody titers to NDV and H5N1 were collected at 3 weeks and …
Antibiotic Resistance Profile Of Enterobacteriaceae Isolated From Healthy Pigs In The Republic Of Armenia, Yura Shirvanyan, Irma Artushyan, Lilit Hovsepyan, Ashkhen Shirvanyan, Elmira Ghazaryan, Tigran Markosyan
Antibiotic Resistance Profile Of Enterobacteriaceae Isolated From Healthy Pigs In The Republic Of Armenia, Yura Shirvanyan, Irma Artushyan, Lilit Hovsepyan, Ashkhen Shirvanyan, Elmira Ghazaryan, Tigran Markosyan
The Thai Journal of Veterinary Medicine
The rising prevalence of antimicrobial resistance (AMR) among Enterobacteriaceae in livestock presents a significant threat to both animal and human health. This study investigates the antibiotic resistance profiles of Enterobacteriaceae isolated from 160 samples collected from the lymph nodes of healthy pigs in Armenia. Fifty isolates were identified, including Escherichia coli (24), Klebsiella spp. (10), Salmonella spp. (6), Raoultella ornithinolytica (4), Pseudomonas aeruginosa (4), and Proteus mirabilis (2). Resistance was evaluated using the disk diffusion method against 22 antibiotics from nine classes. Alarmingly, 94.5% of isolates were resistant to clarithromycin and 90.3% to erythromycin, while resistance to cephalothin and amoxicillin …
External Jugular Vein Catheterization Technique For Continuous Blood Sampling In Gilts, Preechaphon Taechamaeteekul, Yosua Kristian Adi, Chutikan Srisang, Pirada Virankabutra, Natchanon Dumniem, Jinda Singlor, Padet Tummaruk
External Jugular Vein Catheterization Technique For Continuous Blood Sampling In Gilts, Preechaphon Taechamaeteekul, Yosua Kristian Adi, Chutikan Srisang, Pirada Virankabutra, Natchanon Dumniem, Jinda Singlor, Padet Tummaruk
The Thai Journal of Veterinary Medicine
External jugular vein blood collection is common in gilts and sows, but continuous sampling for hormonal and pharmacokinetic research requires catheterization. The standard protocol has remained largely unchanged for nearly 40 years. This study aimed to develop a modified external jugular vein catheterization technique in gilts. Ten gilts (72.0 ± 3.4 kg) underwent surgery under general anesthesia after 12-hour fasting. Sedation was induced with intramuscular Xylazine (4.4 mg/kg) and Tiletamine–Zolazepam (2.2 mg/kg), followed by intravenous Thiopental sodium (10 mg/kg). Once anesthetized, gilts were placed in dorsal recumbency, and the external jugular fossa was prepared under sterile conditions. A 10 cm …
Prevalence Study Of Feline Ab Blood Types In Bangkok And Vicinities Of Thailand By Rapid Immunochromatographic Test During 2022-2024, Suwarath Wadeerat, Sinittha Thongwandi, Thitima Tripipat, Teerawut Nedumpun
Prevalence Study Of Feline Ab Blood Types In Bangkok And Vicinities Of Thailand By Rapid Immunochromatographic Test During 2022-2024, Suwarath Wadeerat, Sinittha Thongwandi, Thitima Tripipat, Teerawut Nedumpun
The Thai Journal of Veterinary Medicine
The AB blood group system is a key classification for feline blood types, categorizing them as type A, B, or AB based on red blood cell surface antigens. This study aimed to update the prevalence of feline blood types among domestic and pedigreed cats in Bangkok and vicinities from 2022 to 2024. A total of 114 blood samples, including 76 Domestic Shorthairs (DSH) and 38 pedigreed cats, including 10 breeds, were analyzed using the rapid immunochromatographic feline blood typing. Results revealed that blood type A was predominant, present in 93.86% of cats, consistent with global findings. Blood types B and …
Assessing The Feasibility Of Microneedle Patches For Gnrh Immunocontraception In Mixed-Breed Dogs (Canis Familiaris), Ai-Mei Chang, Hsiao-Hui Huang, Ding-Liang Hou, Zi-Yu Lin, Mei-Chin Chen, Chen-Chih Chen, Jai-Wei Lee
Assessing The Feasibility Of Microneedle Patches For Gnrh Immunocontraception In Mixed-Breed Dogs (Canis Familiaris), Ai-Mei Chang, Hsiao-Hui Huang, Ding-Liang Hou, Zi-Yu Lin, Mei-Chin Chen, Chen-Chih Chen, Jai-Wei Lee
The Thai Journal of Veterinary Medicine
The overpopulation of free-roaming dogs poses significant risks to endemic species, public health, and the environment through predation and disease transmission. While surgical castration is effective, it raises ethical concerns regarding animal welfare. Immuno-castration offers a humane and effective alternative for population control, but a more easily administered and cost-efficient method is needed to enable widespread vaccination efforts. In this study, we aimed to employ self-dissolving microneedle patches for a simple and potentially cost-effective immunization of a recombinant GnRH-based vaccine to control fertility. Eight mongrel dogs were randomly divided into 2 groups (n=4 each) and immunized with the recombinant GnRH-based …
Antimicrobial Peptides: Could It Be An Alternative To Antibiotics In Boar Semen Extender?, Krittika Keeratikunakorn, Panida Chanapiwat, Kampon Kaeoket
Antimicrobial Peptides: Could It Be An Alternative To Antibiotics In Boar Semen Extender?, Krittika Keeratikunakorn, Panida Chanapiwat, Kampon Kaeoket
The Thai Journal of Veterinary Medicine
Since antimicrobial resistance is a major global issue, “One Health” approaches such as the use of antimicrobial peptides (AMPs) was developed as an alternative antimicrobial agent which might be used in pig farms to reduce or replace non-rationale antibiotics usage. Although AMPs showed several effects on antimicrobial agents, including against bacteria, fungi, protozoa, and viruses, as well as effects on host immunity, their most notable property is their ability to kill bacteria without causing damage to the host cell. Two major mechanisms of action of AMPs include membrane-active and intracellular-active. During the past decade, many AMPs have been tested for …
Local Tissue Damage Treatment Of Snake Venom, Suchitra Khunsap
Local Tissue Damage Treatment Of Snake Venom, Suchitra Khunsap
The Thai Journal of Veterinary Medicine
Local tissue damage caused by snake envenomation was a medical problem that caused morbidity and mortality for more than a decade, with no defined treatment guidelines. Nowadays, antivenom is the primary treatment for snakebite, which substantially reduces systemic venom but not significantly reducing local symptoms. We compiled a list of local damage therapies, including antivenom medication, surgery and skin grafting, small molecule medicines, and alternative therapies. Although each was not approved as a standard treatment, it may be a treatment option for tissue damage caused by snake venom. However, antivenoms and most resistant compounds may not be the best strategy …
The Survey Of The Prevalence Of Equine Gastric Ulcer Syndrome (Egus) In Non-Racing Thoroughbred Horses In Thailand, Teerapol Tum Chinkangsadarn, Sangtawan Tubkleaw, Ananya Rungjarusub, Jitsupa Trangkatarn, Kawinthida Thaworn, Parichart Tesena
The Survey Of The Prevalence Of Equine Gastric Ulcer Syndrome (Egus) In Non-Racing Thoroughbred Horses In Thailand, Teerapol Tum Chinkangsadarn, Sangtawan Tubkleaw, Ananya Rungjarusub, Jitsupa Trangkatarn, Kawinthida Thaworn, Parichart Tesena
The Thai Journal of Veterinary Medicine
This study aimed to determine the prevalence, types, and risk factors of Equine Gastric Ulcer Syndrome (EGUS) in non-racing Thoroughbred horses in Thailand. A total of 56 Thoroughbreds, aged 5 to 22 years (mean age: 12.43 ± 4.65 years), were included. Before sedation, a comprehensive history and physical examination were conducted. Gastroscopy was performed to identify gastric ulcers, using the Equine Gastric Ulcer Council 0–4 scoring system for non-glandular ulcers, while glandular ulcers were assessed as present or absent. Data on breed, age, sex, activity status, behavior, appetite, and medical rehistory were collected. The overall prevalence of gastric ulcers was …
Morphological And Scanning Electron Microscopy Characterization Of A Spirurid In A Wild Sunda Pangolin (Manis Javanica), Punnarat Vibulchan, Chong Shin Min, Chiharu Okumura, Piyanan Taweethavonsawat
Morphological And Scanning Electron Microscopy Characterization Of A Spirurid In A Wild Sunda Pangolin (Manis Javanica), Punnarat Vibulchan, Chong Shin Min, Chiharu Okumura, Piyanan Taweethavonsawat
The Thai Journal of Veterinary Medicine
This study identifies and characterizes a spirurid in a wild Sunda pangolin (Manis javanica) using scanning electron microscopy (SEM). Native to Southeast Asia, the Sunda pangolin faces critical threats from poaching, illegal trafficking for its scales and meat, habitat loss, urban conflicts, and disease. Despite this, little is known about the biology of wild Sunda pangolins. In this research, spirurid parasites were recovered from a pangolin fatally injured in a vehicular collision. The parasites were preserved and analyzed with SEM, revealing key morphological features such as papillae, lip-like structures, and an anal opening in females. This study enhances …
Correlation Of Classical Swine Fever (Csf) Antibody Protective Level Detected By Enzyme-Linked Immunosorbent Assay And Serum Neutralization Test, Chairani Ridha Maghfira, Nguyen Thanh Che, Apisit Kittawornrat, Roongroje Thanawongnuwech, Yaowalak Panyasing
Correlation Of Classical Swine Fever (Csf) Antibody Protective Level Detected By Enzyme-Linked Immunosorbent Assay And Serum Neutralization Test, Chairani Ridha Maghfira, Nguyen Thanh Che, Apisit Kittawornrat, Roongroje Thanawongnuwech, Yaowalak Panyasing
The Thai Journal of Veterinary Medicine
Protective antibody against classical swine fever virus (CSFV) is an important parameter used for disease monitoring in CSFV-endemic areas. Enzyme-linked immunosorbent assay (ELISA) is a simple and practical serological assay for CSFV antibody detection. However, the use of CSFV ELISAs in CSFV antibody-positive herds, i.e., CSFVvaccinated or -previously infected herds, was limited by an application of the test results. This study aimed to evaluate the correlation and estimation of protective antibody levels detected by ELISA and serum neutralization assay. A total of 522 negative and positive serums were tested by SN and ELISA in parallel. Comparisons of sample-to-positive (S/P) values …
Immunoinformatics-Based Design And In Vitro Expression Analysis Of A Multi-Epitope Vaccine Against African Swine Fever Virus, Dhithya Venkateswaran
Immunoinformatics-Based Design And In Vitro Expression Analysis Of A Multi-Epitope Vaccine Against African Swine Fever Virus, Dhithya Venkateswaran
Chulalongkorn University Theses and Dissertations (Chula ETD)
African swine fever (ASF) is a lethal haemorrhagic disease affecting domestic and wild pigs, causing severe economic losses globally. The absence of an effective vaccine has hindered ASF control, as traditional approaches are challenged by the virus’s genetic complexity and immune evasion mechanisms. In this study, we employed immunoinformatics to design a multi-epitope vaccine (MEV) against African Swine Fever Virus (ASFV), targeting conserved viral proteins—B646L (p72), CP204L (p30), E183L (p54), and EP402R (CD2v). Antigenic and non-allergenic BL and HL epitopes were selected and assembled with appropriate adjuvant and linkers to construct the MEV. No CTL epitopes were included, as they …
Canine Uterine Fibrosis Associated With Age And Pyometra, Maulida Selma Hanim
Canine Uterine Fibrosis Associated With Age And Pyometra, Maulida Selma Hanim
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study investigated whether aging and uterine pathology drive fibrosis in the canine uterus by quantifying collagen deposition in endometrial and myometrial compartments. Uterine samples from 55 small-sized, intact, nulliparous bitches were classified into five groups according to age and pathological conditions. Healthy group divided into juvenile, young adult, old adult, and the pathological group included cystic endometrial hyperplasia (CEH), and pyometra. Fibrosis was assessed using Masson’s trichrome staining; collagen proportion was quantified with ImageJ and analysed in SAS. Across healthy age groups, collagen proportions in the endometrial stroma, circular myometrium, and longitudinal myometrium did not differ significantly (P > 0.05). …
Expression Of Peroxisome Proliferator-Activated Receptor Alpha In Feline Mammary Carcinomas, Ngoc Anh Van Pham
Expression Of Peroxisome Proliferator-Activated Receptor Alpha In Feline Mammary Carcinomas, Ngoc Anh Van Pham
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to investigate the expression patterns of peroxisome proliferator-activated receptor alpha (PPARα) in normal tissue and feline mammary carcinomas. Thirty feline mammary carcinomas (FMCs) and eight normal mammary tissues were used in this study. In the same FMC cats, tissues were collected from 2 regions which are the neoplastic tissue and the adjacent non-neoplastic tissues. The study was composed of three parts: (1) clinical data collection and histopathological diagnosis; (2) Immunohistochemistry (IHC) evaluation of PPARα, Ki-67, and proliferating cell nuclear antigen (PCNA); and (3) Western blot analysis of PPARα isoforms. The results revealed no significant differences in PPARα …
Diagnostic Approaches And Therapeutic Evaluation In Canine Benign Prostatic Hyperplasia: An Integrated Analysis Of Prostatic Volume, Serum Canine Prostatic Specific Esterase (Cpse) Levels, And Proteomic Profiles, Panthipa Borikappakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Benign prostatic hyperplasia (BPH) is a highly prevalent condition in intact male dogs. However, its diagnosis and clinical management remain limited by the lack of clear thresholds for clinically significant prostatic enlargement, insufficient biomarkers to monitor treatment response, and an incomplete understanding of the molecular mechanisms driving disease progression. To address these gaps, this thesis integrated ultrasonographic, biochemical, and proteomic approaches across three complementary studies. First, the actual to expected normal prostatic volume ratio was evaluated to establish a clinically meaningful cutoff distinguishing subclinical from clinical BPH, providing an imaging-based indicator for early recognition of clinically relevant enlargement. Building on …
Community Ecology Of Domestic Animals And Wildlife At Solid Waste Disposal Sites Near Dong Phayayen – Khaoyai Forest Complex And Its Impacts On Zoonotic Diseases, Paisin Lekcharoen
Community Ecology Of Domestic Animals And Wildlife At Solid Waste Disposal Sites Near Dong Phayayen – Khaoyai Forest Complex And Its Impacts On Zoonotic Diseases, Paisin Lekcharoen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Solid waste disposal sites (SWS) at forest edges represent critical zoonotic transmission hotspots where wildlife, domestic animals, and humans converge. This study characterized host community structure, pathogen circulation, and network topology at SWS adjacent to the Dong Phayayen-Khao Yai Forest Complex, Thailand. Three study phases (2021-2023) comprised: (1) camera trapping at five SWS (3,907 trap-nights); (2) small mammal trapping across four habitats (1,420 individuals, 12 species), ectoparasite collection (20,560 chiggers, 14 species), and molecular pathogen detection; and (3) network analysis of connectivity among habitat, host, chigger, and pathogen. Domestic dogs dominated communities (88.3%), creating simplified assemblages. Potential transmission operated through …