Open Access. Powered by Scholars. Published by Universities.®

Veterinary Medicine Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 91 - 115 of 115

Full-Text Articles in Veterinary Medicine

Follicular Responsiveness To Equine Chorionic Gonadotropin In Cat Species: Study In In Vitro Culture, Ajjima Chansaenroj Jan 2018

Follicular Responsiveness To Equine Chorionic Gonadotropin In Cat Species: Study In In Vitro Culture, Ajjima Chansaenroj

Chulalongkorn University Theses and Dissertations (Chula ETD)

Equine chorionic gonadotropin (eCG) has been commonly used to induce estrus in several felid species. However, the mechanisms by which this gonadotropin regulates cat folliculogenesis are still unclear. In this present study, we investigated 1) the in vitro responsiveness of cat ovarian follicles at different follicle developmental stages to various eCG concentration; 2) tiger antral follicle responsiveness to eCG; 3) the influence of eCG combination with insulin-like growth factor I (IGF-I) and/or stem cell factor (SCF) on cat ovarian follicles at different developmental stages. Study 1, the isolated follicles from the ovaries of 22 cats were classified into three developmental …


Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen Jan 2018

Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Retinal (retinaldehyde) is one of natural vitamin A metabolites. It is widely used in clinical dermatology such as acne, acne scar, photoaging, wrinkles, psoriasis, skin neoplasia and seborrheic dermatitis. Retinal is a pivotal key to regulate keratinocyte proliferation and differentiation in the epidermis resulting in epidermal thickening and inhibit collagen destruction in the dermis. However, topical application of retinal is still irritative to the skin and chemically and photochemically unstable. Topically applied retinal can induce a retinoid dermatitis. This inflammation is induced by an overload of non-physiological amounts of exogenous retinoic acid in the skin. The adverse effects and physicochemical …


Surveillance Of Influenza A Viruses In A Live Bird Market, Yangon, Myanmar During 2017-2018, Khin Thurain Jan 2018

Surveillance Of Influenza A Viruses In A Live Bird Market, Yangon, Myanmar During 2017-2018, Khin Thurain

Chulalongkorn University Theses and Dissertations (Chula ETD)

Live bird markets play a significant role in highly pathogenic avian influenza (HPAI) virus spread and transmission. In Myanmar, the first HPAI-H5N1 outbreak was reported in 2006. Since 2014, routine influenza A virus surveillance in LBMs have been conducted in Myanmar by the Livestock Breeding and Veterinary Department in cooperation with FAO. However, there is limited information on virus characterization and evolution of influenza viruses in Myanmar. The objectives of this thesis were to detect influenza virus subtypes circulating in different poultry species from Mingalar-Taung-Nyunt live bird market (MTN-LBM) and to determine genetic characteristics and genetic diversity of influenza A …


Genome Characterization Of Hahella Chejuensis Strain Hn01, A Pathogen Of Red Egg Disease In Tilapia (Oreochromis Sp.), Putu Cri Devischa Gallantiswara Jan 2018

Genome Characterization Of Hahella Chejuensis Strain Hn01, A Pathogen Of Red Egg Disease In Tilapia (Oreochromis Sp.), Putu Cri Devischa Gallantiswara

Chulalongkorn University Theses and Dissertations (Chula ETD)

Red eggs disease is an emerging disease occurred in Tilapia hatcheries which caused by a Gram-negative bacterium called Hahella chejuensis HN01. The disease infects to all the stage of fish eggs and reduces the hatchability. However, there are limited study about the bacterial pathogenicity. In this study, we analyzed the phylogenetic relationship and characterized the virulence traits of Hahella chejuensis by using genomic approach. The bacterial genome was sequenced using Illumina Miseq platform. The phylogenetic tree based on several housekeeping genes confirmed that the bacterium was belong to Genus Hahella and species chejuensis. the Average Nucleotide Identity calculation with the …


ผลของการเสริมกากชาต่อสมรรถภาพการผลิต การย่อยได้ปรากฏ และ การผลิตก๊าซมีเทนของแพะนมลูกผสม, รพีพัฒน์ สันโดษ Jan 2018

ผลของการเสริมกากชาต่อสมรรถภาพการผลิต การย่อยได้ปรากฏ และ การผลิตก๊าซมีเทนของแพะนมลูกผสม, รพีพัฒน์ สันโดษ

Chulalongkorn University Theses and Dissertations (Chula ETD)

งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาผลของการใช้กากชา ต่อประสิทธิภาพการใช้อาหาร การย่อยได้ปรากฏ การเปลี่ยนแปลงของเมทาโบไลท์ในเลือด และการผลิตก๊าซมีเทน ในอาหารที่ใช้เลี้ยงแพะนมลูกผสม วางแผนการวิจัยแบบสลับ (3 x 3 crossover design) โดยใช้แพะนมลูกผสมพันธุ์ซาแนนจำนวน 9 ตัว น้ำหนักเฉลี่ย 30 ± 3.50 กิโลกรัม เป็นแม่แพะที่ผ่านการคลอดมาแล้ว (multiparous) และอยู่ในช่วงให้ผลผลิตน้ำนมหลังคลอด (lactation) การทดลองแบ่งออกเป็น 2 ช่วง โดยในช่วง 14 วันแรกจะเป็นช่วงของการปรับตัว ช่วงที่เหลืออีก 7 วันจะเป็นช่วงของการเก็บตัวอย่างและข้อมูล แพะแต่ละตัวได้รับอาหารทั้งสามสูตรที่มีการเสริมกากชาลงในสัดส่วนที่ 0 5 และ 10 เปอร์เซ็นต์น้ำหนักแห้งในรูปของอาหารผสมเสร็จ (Total mixed ration; TMR) (กลุ่มที่ 1 2 และ 3 ตามลำดับ) มีการคำนวณระดับโปรตีนและพลังงานเท่ากันทุกสูตร (isonitrogenous and isocaloric diets) ทำการเก็บตัวอย่าง ได้แก่ อาหาร เลือด ปัสสาวะ มูล น้ำนม และของเหลวจากกระเพาะรูเมน เพื่อที่จะประเมินค่าพารามิเตอร์ที่สังเกตหลายชนิด ผลการศึกษาพบว่า ไม่มีความแตกต่างกันทางสถิติในกลุ่มทดลองของปริมาณการกินได้ ผลผลิตน้ำนม ค่าเมทาโบไลท์ในเลือด (กลูโคส ไตรกลีเซอไรด์ โปรตีนรวม) ค่าพีเอชในกระเพาะรูเมน กรดไขมันระเหย (volatile fatty acids; VFAs) ค่าอัลลานโทอิน (allantoin) ค่าสมดุลไนโตรเจนและผลผลิตก๊าซมีเทน ส่วนประกอบของโปรตีนในน้ำนมในกลุ่มที่ 3 มีความแตกต่างกันทางสถิติ (p<0.05) เมื่อเปรียบเทียบกับกลุ่มที่ 1 และ 2 ค่าการย่อยได้ของวัตถุแห้งในกลุ่มที่ 3 สูงกว่าในกลุ่มที่ 2 อย่างมีนัยสำคัญทางสถิติ (p<0.05) แต่ไม่แตกต่างจากกลุ่มที่ 1 ส่วนกลุ่มที่ 2 มีค่าการย่อยได้ของสารอินทรีย์ โปรตีนและ NDF ต่ำที่สุดในทุกกลุ่ม อย่างไรก็ตาม กลุ่มที่ 3 มีค่าการย่อยได้ของ NDF และ ADF สูงที่สุดเมื่อเปรียบเทียบกับกลุ่มอื่น จากผลการศึกษาสรุปได้ว่า สามารถใช้กากชาได้ถึงระดับ 10 เปอร์เซ็นต์น้ำหนักแห้งในสูตรอาหาร เพื่อเป็นแหล่งโปรตีนในอาหารที่ใช้เลี้ยงแพะนมลูกผสมผสมซาเนนได้ โดยไม่ก่อให้เกิดผลเสียต่อปริมาณการให้ผลผลิตและนิเวศวิทยาในกระเพาะรูเมน อย่างไรก็ตาม การเสริมกากชาที่ระดับ 5 และ 10 เปอร์เซ็นต์น้ำหนักแห้งในสูตรอาหารไม่ส่งผลต่อการผลิตก๊าซมีเทน


Physiological And Immunological Responses Of Porcine Primary Endometrial Cells To Porcine Reproductive And Respiratory Syndrome (Prrs) Virus Infection, Muttarin Lothong Jan 2018

Physiological And Immunological Responses Of Porcine Primary Endometrial Cells To Porcine Reproductive And Respiratory Syndrome (Prrs) Virus Infection, Muttarin Lothong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Porcine reproductive and respiratory syndrome virus (PRRSV) is highly limited to only cell subsets that express PRRSV receptors. Reproductive organ revealing the typical signs of PRRSV infection may be the critical site of problem syndromes. Persistent PRRSV producing re-infection via horizontal or vertical transmission could not be eradicated from herds. This research examined the possibility of porcine endometrium to be a PRRSV permissive cell and serves as the primary cause of the persistent PRRSV. Cellular and immunological in response to PRRSV relevant to viral replication, shedding and re-circulation was assessed. The different outcomes between the different genotypes (type I vs. …


Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum Jan 2018

Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum

Chulalongkorn University Theses and Dissertations (Chula ETD)

The main overall goal of this study is to investigate the application of modified chitosan as a potential vector for apoptotic gene delivery to gonadotropin-releasing hormone receptor (GnRHR)-expressing cells (i.e. testicular cells and mammary cancer cells). This study reported Gonadotropin Releasing Hormone-modified Chitosan (GnRH-CS) nanoparticle as a promising vector for targeted gene delivery, and a GnRH peptide was used for active targeting of a transgene in GnRHR expressing cells. The physiological characterizations of the prepared nanoparticle were investigated by proton nuclear magnetic resonance spectroscopy (1H NMR), Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and Nanosizer. The prepared GnRH-CS was …


Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti Jan 2018

Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti

Chulalongkorn University Theses and Dissertations (Chula ETD)

Diagnosis of Canine Monocytic Ehrlichiosis is in light of anamesis, visualized cytoplasmic morulae, clinical signs and laboratory test result of platelet counts. The PCR technique is always a definitive confirmatory test of Ehrlichia canis infection. However, the drawback of PCRs test is crucially needed of laboratory equipments. This drawback is somehow enabled newly DNA based technology to be developed in order to eliminate laborious thermocycler and gel electrophoresis. The LAMP-LFD is on focus by using a single temperature to amplify DNA and no gel electrophoresis involved to detect DNA product. LAMP-LFD is included in DNAsensor test kit that recently developed …


Systems Biology Approach For The Establishment Of Veterinary Bone Tissue Engineering: The Proteomics Of Cbm-Mscs And Cdpscs Osteogenic Models, Sirirat Nantavisai Jan 2018

Systems Biology Approach For The Establishment Of Veterinary Bone Tissue Engineering: The Proteomics Of Cbm-Mscs And Cdpscs Osteogenic Models, Sirirat Nantavisai

Chulalongkorn University Theses and Dissertations (Chula ETD)

The utilization of canine mesenchymal stem cells (cMSCs) with multipotent capabilities has been regarded for possible therapy of incorrigible bone disease. Although various sources of cMSCs show similar characteristics, they are different in osteogenic potential due to their original cellular sources. This study was designed to globally explore and analyze the in vitro differentiation potential and behavior of canine bone-marrow derived mesenchymal stem cells (cBM-MSCs) and canine dental pulp stem cells (cDPSCs) toward osteogenic lineage. An in vitro osteogenic differentiation potential of the cells was preliminarily compared in terms of alkaline phosphatase activity assay and Von Kossa staining. Global study …


Synbiotic Effects Of Jerusalem Artichoke (Helianthus Tuberosus) And Lactobacillus Rhamnosus-Supplemented Diet On Growth Performance, Immunological Parameters And Protection Against Aeromonas Veronii Challenge In Juvenile Red Tilapias (Oreochromis Spp.), Mariya Sewaka Jan 2018

Synbiotic Effects Of Jerusalem Artichoke (Helianthus Tuberosus) And Lactobacillus Rhamnosus-Supplemented Diet On Growth Performance, Immunological Parameters And Protection Against Aeromonas Veronii Challenge In Juvenile Red Tilapias (Oreochromis Spp.), Mariya Sewaka

Chulalongkorn University Theses and Dissertations (Chula ETD)

Synbiotics, a synergistic combination of probiotics and prebiotics, are now highlighted as one of the most practical nutritional supplements in red tilapia farms. The aim of the present study was to assess the effect of the dietary inclusion of Jerusalem artichoke, Lactobacillus rhamnosus, or their combination, on serum biochemical, growth performance, intestinal morphology, immune parameters, intestinal bacterial count and protection against Aeromonas veronii in juvenile red tilapia (Oreochromis spp.). One hundred and eighty male red tilapias (average body weight of 14.05±0.42 g) were distributed into six 1000-liter tanks containing water under continuous aeration and an average temperature of 25–28°C. Tilapias …


Application Of Needle-Free Injection Technology For Foot And Mouth Disease Vaccination Via Intradermal Route, Sirirat Wataradee Jan 2018

Application Of Needle-Free Injection Technology For Foot And Mouth Disease Vaccination Via Intradermal Route, Sirirat Wataradee

Chulalongkorn University Theses and Dissertations (Chula ETD)

Foot and mouth disease (FMD) is an endemic disease in Thailand and caused severe economic loses. In order to prevent and control disease, the vaccination program is routinely administered for 2-3 times a year via subcutaneous route (SC). Even though, the vaccination is performed regularly, the outbreaks have often reported. The outbreaks occur due to the failure of number of immunity animal in population or herd immunity. The limitation of vaccine distribution to all animal population and difficulty of cattle restraint are forcible several farmers to failing to vaccinate their animals. Based on previous studies, the intradermal route (ID) can …


The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad Jan 2018

The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad

Chulalongkorn University Theses and Dissertations (Chula ETD)

Porcine epidemic diarrhea is caused by porcine epidemic diarrhea virus (PEDV), which causes swine watery diarrhea and higher mortality rates in piglets less than one week of age. Outbreaks of PED affect to economic loss, especially in a swine industrial country. Many strategies were used for preventing the outbreak and infection of PEDV, especially maternal antibody stimulation in pigs and then transfer to piglet through colostrum or milk. Thus, the investigation of antibody level for the situation on the farm is required. The method which convenient and rapid than viral neutralization (VN) test is an enzyme-linked immunosorbent assay (ELISA). The …


Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij Jan 2018

Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij

Chulalongkorn University Theses and Dissertations (Chula ETD)

Brugia pahangi is a major causative agent of animal lymphatic filariasis, one of the neclected tropical disease. Recent studies have also indicated that B. pahangi can cause clinical infection in human, with clinical appearances which are consistent with human lymphatic filariasis. Nowadays, the recognition of Wolbachia as new alternative drug choice for treatment and control of lymphatic filariasis is the most important in anti-filarial chemotherapy. Since, Wolbachia play important roles, including the development, viability, fertility and fecundity of filarial parasites. Depletion of Wolbachia results in sterilization, stunting and death of filarial worms. In this study, we investigated the effects of …


Genome Characterization Of Quinolone Resistance Associated Genes Of Flavobacterium Columnare Isolated From Columnaris Diseased Asian Sea Bass (Lates Calcarif)Er), Putita Chokmangmeepisarn Jan 2018

Genome Characterization Of Quinolone Resistance Associated Genes Of Flavobacterium Columnare Isolated From Columnaris Diseased Asian Sea Bass (Lates Calcarif)Er), Putita Chokmangmeepisarn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Flavobacterium columnare is Gram negative bacteria which caused columnaris disease in various kinds of freshwater fishes. This study is the first report of F. columnare infection in freshwater culturing Asian sea bass in Thailand. Phenotypic characterization, antimicrobial susceptibility test and quinolone resistant-associated genes of F. columnare were performed. A total 15 of F. columnare were isolated from diseased fishes and phylogenetic analysis revealed that these isolates were belonged to genetic group 2 and 4. From disk diffusion test results, 5 and 6 isolates were resistant to oxolinic (OA) and nalidixic acid (NA) respectively. The highest MIC values to OA and …


Appropriate Campylobacter Detection Method And Genetic Variation Of Campylobacter Jejuni In Broilers, Natnicha Phetsri Jan 2018

Appropriate Campylobacter Detection Method And Genetic Variation Of Campylobacter Jejuni In Broilers, Natnicha Phetsri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Campylobacter has been known as an important cause of gastroenteritis in humans. The primary source is raw or undercooked poultry meat. Previous study showed that Campylobacter isolated from slaughterhouses were associated with Campylobacter isolated from broiler farms. Thus, detection of Campylobacter flock status and sorting flocks prior to slaughtering processes may help prevent Campylobacter contamination between Campylobacter-positive and negative flocks during slaughtering processes. Unfortunately, appropriate sample type and isolation method have not been clearly specified for Campylobacter detection at the farm level. Because Campylobacter are fastidious bacteria, improper detection method can attribute to false negative results. Therefore, the objectives of …


Development Of Reverse Transcription Loop-Mediated Isothermal Amplification Combine With Lateral Flow Device As A Detection Assay For Swine Influenza Virus, Albarriyati Ummi Asih Jan 2018

Development Of Reverse Transcription Loop-Mediated Isothermal Amplification Combine With Lateral Flow Device As A Detection Assay For Swine Influenza Virus, Albarriyati Ummi Asih

Chulalongkorn University Theses and Dissertations (Chula ETD)

Swine influenza causes high morbidity and low mortality in pigs. The disease spreads rapidly in pig farms causing the delay of pig weight to reach market. Moreover, pigs play important role as "mixing vessel" of influenza viruses. Pigs can support infection and replication of influenza viruses from avian, human and swine origins. These lead to major concerns of the important of swine influenza which are not only the economic impacts but also the human health. There is the need of accurate and rapid diagnosis for swine influenza virus (SIV) to minimize further spreading of the viruses in pig population and …


Pedv Monitoring Using Oral Fluid, Feces And Surface Swab Samples After The Ped Outbreak, Busayamas Jantrasakul Jan 2018

Pedv Monitoring Using Oral Fluid, Feces And Surface Swab Samples After The Ped Outbreak, Busayamas Jantrasakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 220 pooled samples from 3 collection times were conducted. Eighty pooled samples from the first collection at 1 month after PED outbreak (1MAO) included 10 pooled oral fluid samples, 30 pooled fecal samples and 40 pooled surface swab samples. Eighty-five pooled samples from the second collection at 2MAO included 10 pooled oral fluid samples, 30 pooled fecal samples and 45 pooled surface swab samples. Fifty-five pooled samples from the third collection at 8MAO included 5 pooled oral fluid samples, 15 pooled fecal samples and 35 pooled surface swab samples. All samples collected from the PED-affected swine farm …


Phenotypic And Genotypic Characteristics Of Extended-Spectrum Β-Lactamase (Esbl) Production And Colistin-Resistance In Salmonella Enterica And Escherichia Coli Isolated From​ Pigs And Their Meat Products In The Border Provinces Between Thailand And Cambodia, Lao Pdr And Myanmar, Kyaw Phyoe Sunn Jan 2018

Phenotypic And Genotypic Characteristics Of Extended-Spectrum Β-Lactamase (Esbl) Production And Colistin-Resistance In Salmonella Enterica And Escherichia Coli Isolated From​ Pigs And Their Meat Products In The Border Provinces Between Thailand And Cambodia, Lao Pdr And Myanmar, Kyaw Phyoe Sunn

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 809 samples of pig rectal swab from slaughterhouses (n=441) and pork from retail market (n=368) were collected in the border provinces among Thailand, Cambodia, Lao PDR and Myanmar between October 2016 and March 2017. The objective of this study was to determine resistance to extended-spectrum ß-lactams (ESBLs) and colistin in Salmonella enterica and Escherichia coli. A total of Salmonella (n=463) and E. coli (n=767) were collected and determined for the ESBL-production and for the Minimum Inhibitory Concentrations (MICs) of colistin and; the presence of ESBL gene and mcr gene. The results showed that the prevalence of Salmonella …


Genetic Characteristics Of Avian Influenza Viruses Isolated From Ducks In Java Island, Indonesia Year 2015-2017, Lestari - Jan 2018

Genetic Characteristics Of Avian Influenza Viruses Isolated From Ducks In Java Island, Indonesia Year 2015-2017, Lestari -

Chulalongkorn University Theses and Dissertations (Chula ETD)

Avian influenza becomes public health concern over years due to the serious impacts in both animal and human health. This study aimed to identify and characterize avian influenza viruses isolated from ducks in Java Indonesia during 2015-2017. Total 50 samples of previously identified as avian influenza viruses were acquired from the virus/culture collections of Disease Investigation Center (DIC) Wates Yogyakarta, Indonesia. The samples were recovered from either the avian influenza surveillance or avian influenza outbreaks in ducks in 3 provinces, East Java (n=26), Central Java (n=16), and Yogyakarta (n=8). Then the samples were processed for influenza A virus screening by …


Detection Of Antimicrobial Resistance Determinants In Vibrio Parahaemolyticus Isolated From Cultivated Oysters And Estuarine Waters, Winn Khant Jan 2018

Detection Of Antimicrobial Resistance Determinants In Vibrio Parahaemolyticus Isolated From Cultivated Oysters And Estuarine Waters, Winn Khant

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, we aimed to detect antimicrobial resistance determinants and virulence factor genes in V. parahaemolyticus isolates from cultivated oysters and estuarine waters in southern Thailand. A total of 594 V. parahaemolyticus isolates were collected from pooled oysters (n=361) and estuarine waters (n=233). The samples were collected monthly between March 2016 and February 2017 from Thap Put district, Phang Nga province in southern Thailand. Confirmation of V. parahaemolyticus was carried out by PCR assay detecting species-specific (tlh) gene and the presence of virulence genes (tdh and trh). Antimicrobial susceptibility test was performed in eight antimicrobials, and the occurrence of …


Biomechanical And Biological Properties Of Cryopreserved Canine Amniotic Membrane, Nathawan Withavatpongtorn Jan 2018

Biomechanical And Biological Properties Of Cryopreserved Canine Amniotic Membrane, Nathawan Withavatpongtorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Amniotic membrane (AM) is the innermost fetal membrane. Due to its many known properties, human AM is a favorable corneal graft. Cryopreservation at -80ºC maintains most of biological properties. Due to shortage of supply, AM of other species are studied. The objective of this study is to explore the biomechanical and biological properties of canine AM (CAM) after cryopreservation for 7 and 30 days. CAMs were collected from healthy bitches undergoing cesarean sections. After preservation, they were tested for tensile strength by Universal Testing Machine, transparency by spectrophotometer, sterility by microbial culture, cell viability by trypan blue staining, and histological …


The Efficiency Of Pcso-524 On Feline Osteoarthritis Associated With Chronic Kidney Disease, Pemika Dulyapraphant Jan 2018

The Efficiency Of Pcso-524 On Feline Osteoarthritis Associated With Chronic Kidney Disease, Pemika Dulyapraphant

Chulalongkorn University Theses and Dissertations (Chula ETD)

Twenty-six osteoarthritic cats concurrent with chronic kidney disease (CKD) enrolled in this study. All cats were divided randomly into 2 groups; control group (n=12) received placebo and treatment group (n=14) received PCSO-524 for 60 days. Cats had verified stable CKD stage II and had treated and followed up for CKD more than 3 months were included in our study. Before starting the study (day 0), all cats were taken the coxofemoral joint radiographic imaging. Only cats with the radiographic osteoarthritic lesion(s) were recruited. All of them had blood profile check-up, urinalysis, blood pressure measurement, lameness score assessment, acute and chronic …


Chondroprotective Efficacy Of Pcso-524 On Canine Osteoarthritis Secondary To Medial Patellar Luxation, Ratthanan Sathienbumrungkit Jan 2018

Chondroprotective Efficacy Of Pcso-524 On Canine Osteoarthritis Secondary To Medial Patellar Luxation, Ratthanan Sathienbumrungkit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Fifty stifles from Pomeranians and Chihuahuas with over five years old were enrolled in this study, which are 8 normal stifles and 42 medial patellar luxation (MPL) stifles. All MPL stifles were assigned randomly into 2 groups, including control and treatment groups. The control group was received placebo daily for 16 weeks, while treatment group was fed with PCSO-524 for 16 weeks. Lameness score, ultrasonographic findings, radiographic OA score and owner questionnaire (cBPI) were assessed at pre-treatment (D0) and post-treatment at week 2, 4, 8, 12 and 16. The ultrasonographic evaluations consisted of synovial fluid, articular cartilage, bone surface and …


Comparative Clinical Outcomes Of Elongated Soft Palate In Brachycephalic Dogs By Surgical Treatment Using The Ultrasonic Scalpel And Bipolar Sealing Device Techniques, Varit Wijitratanagorn Jan 2018

Comparative Clinical Outcomes Of Elongated Soft Palate In Brachycephalic Dogs By Surgical Treatment Using The Ultrasonic Scalpel And Bipolar Sealing Device Techniques, Varit Wijitratanagorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Brachycephalic airway obstruction syndromes (BAOS) are the most common respiratory problems in brachycephalic dogs. Surgical treatment which are staphylectomy and alaplasty is commonly used for correction primary lesions of BAOS. The purpose of this study is to compare clinical outcome of post staphylectomy using ultrasonic scalpel and bipolar sealing devices. Twenty brachycephalic dogs were included for staphylectomy and randomly separated into two groups. Surgical time, perioperative blood loss, pain score and clinical score of respiratory function were recorded at day 1 7 14 21 and 28 post-operative. The excised soft palate at day 0 and 21 was recorded lateral thermal …


The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya Jan 2018

The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya

Chulalongkorn University Theses and Dissertations (Chula ETD)

Monosodium glutamate (MSG) is composed of sodium salt and amino acids that is commonly used to enhance food taste. Although it is safe at consumption level, the adverse effect of MSG had been reported. The present research was intended to evaluate the effect of MSG on the brain, liver, kidney, testes, and ovaries of zebrafish (Danio rerio) which were exposed from embryo stage to adult stage, along with the analyzing of the fertilization rate and hatching rate of zebrafish embryos. From the observation of histopathological changing of different organs of zebrafish after exposed to 10, 100, and 1000 ppm MSG …