Rehabilitation and Therapy Commons^™

The Effect Of Breathing Exercise On Hemodynamics And Heart Rate Variability Parameters In Hypertensive Patients, Sirinut Chaiduang

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this research aimed to investigate the effect of breathing exercises (BE) on hemodynamics and heart rate variability (HRV) parameters in hypertensive patients. This research comprised three studies, including 1) a systematic review investigating the effectiveness of each type of BE (deep and slow, manipulated nostril, prolonged expiration, and cycle of breathing) on hemodynamics and HRV parameters in hypertensive patients. 2) A study comparing the effect of BE (deep and slow, pursed lips, and bee-humming) on hemodynamics and HRV parameters in hypertensive patients. And 3) a study comparing the combined effect of developed BE on hemodynamics and HRV …

Musculoskeletal Disorders, Perceived Stress, And Ergonomic Risk Factors Among Pakistani Smartphone Esports Athletes, Muhammad Athar Khan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Smartphone eSports athletes face various health risks due to prolonged sitting and poor posture.Objective: To investigate the frequency of musculoskeletal disorders, perceived stress levels, health risks and ergonomic risk factors among smartphone eSports athletes and determine the association between levels of perceived stress and MSDs.Methods: A cross-sectional study was conducted on 145 participants. Nordic Musculoskeletal Questionnaire, Perceived Stress Scale (PSS-10), questionnaire on health risks and rapid upper limb assessment (RULA) were used to collect data. The chi-square test determined the association between MSDs and perceived stress.Results: The study revealed that neck pain was the most prevalent issue, affecting 41.4% …

The Influence Of Therapeutic Body Positions On Hemodynamics And Respiration In Adults With And Without Obesity, Ruchada Sriamad

Chulalongkorn University Theses and Dissertations (Chula ETD)

The primary objective of this research was to investigate the impact of therapeutic body positions on hemodynamic and respiratory responses in adults with and without abdominal obesity. This research comprises three studies: 1) a systematic review and meta-analyses to investigate the influence of various body positions on hemodynamic and respiratory variables in healthy adults; 2) a study on hemodynamic responses during therapeutic body positions in adults with and without abdominal obesity; 3) a study on respiratory responses during therapeutic body positions, comparing obese and non-obese adults. The results from the systematic review revealed that different positions elicit distinct hemodynamic and …

Lower-Limb Wearable Resistance Overloads Joint Angular Velocity During Early Acceleration Sprint Running, Erin H. Feser, Jonathon Neville, Danny Wells, Shelley Diewald, Mai Kameda, Neil E. Bezodis, Kenneth Clark, Ryu Nagahara, Paul Macadam, Aaron M. Uthoff, Farhan Tinwalla, John B. Cronin

Funded Scholarship

Lower-limb wearable resistance (WR) facilitates targeted resistance-based training during sports-specific movement tasks. The purpose of this study was to determine the effect of two different WR placements (thigh and shank) on joint kinematics during the acceleration phase of sprint running. Eighteen participants completed maximal effort sprints while unloaded and with 2% body mass thigh- or shank-placed WR. The main findings were as follows: 1) the increase to 10 m sprint time was small with thigh WR (effect size [ES] = 0.24), and with shank WR, the increase was also small but significant (ES = 0.33); 2) significant differences in peak …

Health Profession Students' Interprofessional Socialization And Values Toward A College-Based Virtual Interprofessional Education Activity, Denise Claiborne, Praveen Durgampudi, Anne C. Dumadag, Emily J. Hawkins, Patricia Laverdure, Amy Laurie Meeker, Barbara Kraj, Angela Wilson, Muge Akpinar-Elci

Dental Hygiene Faculty Publications

Purpose: The inclusion of interprofessional education (IPE) is essential for the health professions curricula and establishes the expectation of collaborative patient-centered care. The COVID-19 pandemic has required educators to develop innovative methods for IPE student engagement. The purpose of this study was to evaluate a college-based virtual IPE activity for first-year health profession students and measure their interprofessional socialization and values (ISVS) toward IPE teams. The validated interprofessional socialization and valuing scales (ISVS-9A/9B) were used.

Methods: A one-group pre-post-test design examined health profession students' ISVS from seven health programs before and after a virtual IPE activity. The IPE activity was …

Cognitive Challenge As A Probe To Expose Sex- And Age-Related Differences During Static Contractions, Hugo M. Pereira, Sandra K. Hunter

Exercise Science Faculty Research and Publications

Despite activities of daily living being frequently performed simultaneously with a cognitive task, motor function is often investigated in isolation, which can hinder the applicability of findings. This brief review presents evidence that 1) performing a cognitive challenge simultaneously with a motor task can negatively impact force steadiness and fatigability of limb muscles during a static contraction, 2) the negative impact on old adults (>65 years old), particularly older women is greater than young when a cognitive challenge is simultaneously performed with a static motor task, 3) age-related mechanisms potentially explain impairments in motor performance in the presence of …

“It’S About Being Healthy”; A Novel Approach To The Socio-Ecological Model Using Family Perspectives Within The Latinx Community, Bethany Korom, Meghan Malloy, Caroline Remmers, Mari Cevilla, Kelly Dione, Paula E. Papanek, Jeffrey Condit, David Nelson

Exercise Science Faculty Research and Publications

Background

The Latinx community is at risk for obesity, type 2 diabetes, and other chronic illnesses. Culturally appropriate, community facing physical activity (P.A.) and nutrition programs may provide the basis for families to improve their health status. Our objectives are as follows: 1. To investigate synergistic factors within this type of program that play a role in creating an environment for participants to learn and practice healthy behaviors. 2. To apply factors into a novel model of components that support health and wellness. 3. To design an intervention for future implementation and evaluation.

Methods

A two-year P.A. and nutrition program, …

Advancing Prosthetic Design Using Neural And Mechanical Dynamics, Kacie E. Hanna

Graduate Theses, Dissertations, and Problem Reports (ETD)

Limb loss poses a significant challenge to mobility and the performance of daily activities. Currently, nearly half of the amputees using powered prosthetics abandon their device due to inadequate limb coordination and movement control abilities. In the healthy system, passive and neural dynamics facilitate the synchronized activation of muscles necessary for coordinated movement. However, in the amputee, the system is disrupted. The goal of this research is to use neural and mechanical dynamics to inform the design of prosthetic devices in order to restore intuitive control and coordinated limb movement.

The first aim of this research is to investigate neural …

Advancing Medical Technology For Motor Impairment Rehabilitation: Tools, Protocols, And Devices, Matthew Yough

Graduate Theses, Dissertations, and Problem Reports (ETD)

Excellent motor control skills are necessary to live a high-quality life. Activities such as walking, getting dressed, and feeding yourself may seem mundane, but injuries to the neuromuscular system can render these tasks difficult or even impossible to accomplish without assistance. Statistics indicate that well over 100 million people are affected by diseases or injuries, such as stroke, Parkinson’s Disease, Multiple Sclerosis, Cerebral Palsy, peripheral nerve injury, spinal cord injury, and amputation, that negatively impact their motor abilities. This wide array of injuries presents a challenge to the medical field as optimal treatment paradigms are often difficult to implement due …

The Immediate Effects Of The Nunee Patellar Support On Individuals With Patellofemoral Pain Syndrome, Nick Linn

Graduate Theses, Dissertations, and Problem Reports (ETD)

Patellofemoral pain syndrome (PFPS) is a common form of anterior knee pain caused by general overuse, muscular weakness or strength imbalances, and poor movement coordination leading to abnormal alignment or mal-tracking of the patella. Recent guidelines do not recommend the use of a knee orthosis due to a lack of evidence supporting their effectiveness. A new patellar support (NuNee, K-Neesio LLC.) which uses distraction force to relieve pressure placed on the patella, has been proposed. The purpose of this study was to examine the immediate effects of the NuNee patellar support on perceived pain, biomechanics, and function in individuals with …

The Experience Of Meaningful Rehabilitation As Perceived By People With Chronic Pain: A Phenomenological Study, Katrina J. Liddiard, Annette J. Raynor, Helen Dejong, Cary A. Brown

Research outputs 2022 to 2026

BACKGROUND: People with chronic pain may seek rehabilitation to reduce pain and restore productivity and valued roles. Theoretically, a biopsychosocial approach makes rehabilitation more meaningful, however, the limited research on meaningful rehabilitation predominantly describes the perspective of therapists and researchers. The client's perspective of meaningfulness in rehabilitation is lacking. OBJECTIVE: To investigate the experience of meaningfulness in rehabilitation from the perspective of people with chronic pain. METHODS: Qualitative, semi-structured interviews were conducted with Australian adults who had chronic pain and recent experience of occupational therapy or physiotherapy. Sampling continued until thematic saturation occurred. Transcripts were coded and analyzed using theory-driven …

Delivering Constraint-Induced Movement Therapy In Stroke Rehabilitation Requires Informed Stakeholders, Sufficient Resources And Organisational Buy-In: A Mixed-Methods Systematic Review, Ashan Weerakkody, Jocelyn White, Claire Hill, Erin Godecke, Barby Singer

Research outputs 2022 to 2026

Objective: To summarise and synthesise the qualitative literature relating to constraint-induced movement therapy (CIMT) among stroke survivors, carers, therapists and rehabilitation service managers. Design: Systematic review of qualitative studies. Quantitative studies using survey data were also included if they investigated perceptions and/or experiences related to CIMT. Data sources: Cochrane Library, Medline, JBI, Emcare, Embase, PsycInfo, CINAHL, PEDro, OT Seeker and NICE from inception to January 2022. Data extraction and synthesis: Two reviewers independently extracted data from the included studies and assessed comprehensiveness of reporting using established tools. Thematic synthesis was undertaken to synthesise findings for studies using focus groups and …

Therapeutic Frameworks In Integration Sessions In Substance-Assisted Psychotherapy: A Systematised Review, Sascha B. Thal, Paris Baker, Jonathon Marinis, Michelle Wieberneit, Jason M. Sharbanee, Raimundo Bruno, Petra M. Skeffington, Stephen J. Bright

Research outputs 2022 to 2026

Serotonergic psychedelics and related substances have been explored as potential adjuncts in substance-assisted psychotherapy (SAPT) for treating various disorders. SAPT can be divided into three phases: preparation, administration and integration. Integration is commonly defined as the comprehension and effective application of insights from psychedelic experiences into everyday life. However, there is limited research regarding the most appropriate therapeutic approach during SAPT. In this article, we discuss the current evidence for different therapeutic frameworks for integration sessions when serotonergic psychedelics and entactogens are used as adjuncts to psychotherapy. We conducted a systematised review of the literature following PRISMA guidelines and searched …

The Effects Of Cognitive-Linguistic Interventions To Treat Aphasia In The First 90 Days Post-Stroke: A Systematic Review, Emily Eley, Maayken Van Den Berg, Miranda L. Rose, John E. Pierce, Abby Foster, Edwina Lamborn, Sarah D’Souza, Erin Godecke, Lucette Lanyon, Ciara Shiggins, Ian Kneebone, Caroline Baker

Research outputs 2022 to 2026

Background: Cognitive-linguistic interventions for aphasia are behavioural-based approaches to therapy that aim to treat language impairment skills post-acquired brain injury. The purpose of cognitive-linguistic intervention is to restore and rehabilitate language impairment skills through targeting phonologic, semantic and syntactic systems, which may support goals to improve everyday communication. Aims: The aim of this systematic review was to investigate the effects of cognitive-linguistic interventions on language processing for aphasia in the first 90 days post-stroke. Secondary aims include the investigation of the effects of these interventions on functional communication and quality of life. Methods: A systematic search was conducted across six …

Exploring The Use Of Photovoice In Understanding The Lived Experience Of Neurological Conditions: A Scoping Review And Reflexive Thematic Analysis, James Smith, Andre Nels, Laura Emery, Mandy Stanley

Research outputs 2022 to 2026

People living with neurological conditions such as multiple sclerosis, Parkinson’s disease and dementia may experience physical impairment, social disengagement, cognitive issues, and emotional disturbances. While qualitative research utilising in-depth interviews can access lived experience perspectives, the use of photovoice has the potential to obtain rich insights that include images and raise community awareness. The purpose of this scoping review was to document salient themes relating to the lived experience of neurological conditions as reported in photovoice studies. Following established scoping review methods of the Joanna Briggs Institute, a comprehensive search of five electronic databases, including MEDLINE, EMBASE, PSYCHINFO, CINAHL, and …

Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh

Research outputs 2022 to 2026

Purpose: To determine the feasibility, safety and preliminary efficacy of a telehealth supervised exercise programme in patients with advanced melanoma receiving checkpoint inhibitor therapy. Methods: A 8-week non-randomised feasibility pilot trial utilising a telehealth delivered multimodal exercise programme undertaken thrice weekly with assessments at baseline and post-intervention. The study was considered feasible if there were no severe or life-threatening adverse events as a result of exercise, and three or more of the following criteria were met: the recruitment rate was > 50%, completion rate was > 80%, median programme attendance was > 75%, median exercise compliance > 75%, and average tolerance was > 70%. Preliminary …

Economic Evaluation Of The Very Early Rehabilitation In Speech (Verse) Intervention, J. Kim, G. Sookram, Erin Godecke, Emily Louise Brogan, Elizabeth Armstrong, F. Ellery, T. Rai, M. L. Rose, Natalie Ciccone, S. Middleton, A. Holland, G. J. Hankey, J. Bernhardt, D. A. Cadilhac

Research outputs 2022 to 2026

Introduction: There is limited evidence on the costs and outcomes of patients with aphasia after stroke. The aim of this study was to estimate costs in patients with aphasia after stroke according to the aphasia therapies provided.

Methods: A three-arm, prospective, randomized, parallel group, open-label, blinded endpoint assessment trial conducted in Australia and New Zealand. Usual ward-based care (Usual Care) was compared to additional usual ward-based therapy (Usual Care Plus) and a prescribed and structured aphasia therapy program in addition to Usual Care (the VERSE intervention). Information about healthcare utilization and productivity were collected to estimate costs in Australian dollars …

Unlocking The Restraint—Development Of A Behaviour Change Intervention To Increase The Provision Of Modified Constraint-Induced Movement Therapy In Stroke Rehabilitation, Ashan Weerakkody, Robyn Emmanuel, Jocelyn White, Erin Godecke, Barby Singer

Research outputs 2022 to 2026

Background: Strong evidence supports the provision of modified constraint-induced movement therapy (mCIMT) to improve upper limb function after stroke. A service audit identified that very few patients received mCIMT in a large subacute, early-supported discharge rehabilitation service. A behaviour change intervention was developed to increase the provision of mCIMT following an unsuccessful ‘education only’ attempt. This paper aims to systematically document the steps undertaken and to provide practical guidance to clinicians and rehabilitation services to implement this complex, yet effective, rehabilitation intervention. Methods: This clinician behaviour change intervention was developed over five stages and led by a working group of …

Physical Activity And Exercise With Blood Flow Restriction As Medicine During The Covid-19 Pandemic And Beyond, Isaac J. Wedig

Dissertations, Master's Theses and Master's Reports

During the COVID-19 pandemic, physical activity levels have decreased and sitting time has increased. This is a major concern as physical inactivity increases the risk for severe COVID-19 outcomes. Evidence also indicates that COVID-19 survivors can experience reduced physical function (i.e., ability to complete daily living activities) long after acute illness. Currently, there are no evidence-based guidelines for recovering physical function following COVID-19 infection. Exercise with blood flow restriction (BFR) presents a promising rehabilitation strategy as the benefits of traditional exercise can be achieved using lower intensities. However, several barriers such as cost, access to equipment, and lack of standardized …

Examining The Lived Experiences Of Families With Children With Developmental Disabilities Participating In Recreational Dance Programs, Isabella Seguin

Theses and Dissertations (Comprehensive)

Objective

Families with children with developmental disabilities (DDs) experience effects on family functioning and will often turn to physical activity (e.g., dance) to mitigate these effects. This research examines the lived experiences of families with children with DDs participating in recreational dance programs to understand the myriad of effects on all participants: children with DDs, families, and dance instructors.

Methods

In order to fully understand the lived experiences of participants, phenomenology was used as the theoretical orientation to guide this research. Each case (5 cases, N=19) consisted of a primary parent, a child with a developmental disability, sibling(s) (if applicable), …

Psychological Readiness In Injured Student-Athletes When Returning To Sport, Samantha J. Burelle

Theses and Dissertations (Comprehensive)

The physical component of recovery is pertinent to success in sport performance, yet there has been an increase in awareness of psychological symptoms and psychological distress experienced by injured athletes. Thus, the psychological aspect of injuries and return to sport (RTS) process cannot be ignored. Psychological readiness (PR) is described by Podlog et al. (2015), Donald (2019), and Podlog et al. (2022) as a dynamic psychological process including factors of realistic expectation, confidence, motivation, and focus. PR addresses the psychological component necessary for a successful RTS. Measurement tools have been developed to assess PR, yet not all factors of PR …

The Association Between Payer Source And Traumatic Brain Injury Rehabilitation Outcomes: A Tbi Model Systems Study, Anthony H Lequerica, Angelle M Sander, Monique R Pappadis, Jessica M Ketchum, Marissa Jaross, Stephanie Kolakowsky-Hayner, Amanda Rabinowitz, Librada Callender, Michelle Smith

Faculty, Staff and Students Publications

OBJECTIVE: To examine the relationship between payer source for acute rehabilitation, residential median household income (MHI), and outcomes at rehabilitation discharge after traumatic brain injury (TBI).

SETTING: Acute inpatient rehabilitation facilities.

PARTICIPANTS: In total, 8558 individuals enrolled in the Traumatic Brain Injury Model Systems (TBIMS) National Database who were admitted to inpatient rehabilitation between 2006 and 2019 and were younger than 64 years.

DESIGN: Secondary data analysis from a multicenter longitudinal cohort study.

MAIN MEASURES: Payer source was divided into 4 categories: uninsured, public insurance, private insurance, and workers' compensation/auto. Relationships between payer source with residential MHI, rehabilitation length of …

Specialized Intensive Inpatient Rehabilitation Is Crucial And Time-Sensitive For Functional Recovery From Disorders Of Consciousness, Bei Zhang, Katherine O'Brien, Jean Woo, Bradley Chi, Colton Reeh, Sheng Li, Sunil Kothari

Faculty, Staff and Students Publications

BACKGROUND: Disorders of consciousness (DoCs) after severe brain injury are considered to be conditions with dire prognosis. Despite the accumulating evidence, inpatient rehabilitation is often denied by payers referring to the Medicare/Medicaid criteria, under the assumption that such patients will not "

OBJECTIVE: This study aimed to report on the effectiveness and efficiency of a specialized inpatient DoC rehabilitation program based on measurable clinical parameters.

METHODS: A retrospective cohort study was conducted. The cohort comprised 137 patients with DoC admitted to a specialized acute inpatient rehabilitation program between January 2014 and October 2018. Patients were categorized as having been admitted …

Perceived Care Partner Burden At 1-Year Post-Injury And Associations With Emotional Awareness, Functioning, And Empathy After Tbi: A Tbi Model Systems Study, Daniel W Klyce, Kritzianel Merced, Alexander Erickson, Dawn M Neumann, Flora M Hammond, Angelle M Sander, Jennifer A Bogner, Tamara Bushnik, Joyce S Chung, Jacob A Finn

Faculty, Staff and Students Publications

BACKGROUND: People with traumatic brain injury (TBI) can lack awareness of their own emotions and often have problems with emotion dysregulation, affective disorders, and empathy deficits. These impairments are known to impact psychosocial behaviors and may contribute to the burden experienced by care partners of individuals with TBI.

OBJECTIVE: To examine the associations of emotional awareness, emotional functioning, and empathy among participants with TBI with care partner burden.

METHOD: This multisite, cross-sectional, observational study used data from 90 dyads (participants with TBI and their care partner) 1-year post-injury. Participants with TBI completed the Difficulty with Emotional Regulation Scale (DERS; Awareness, …

The Development Of Self-Healing Model With Massage Therapy And Exercise Therapy For A Wrist Injury, Nofa Anggriawan, Wara Kushartanti, Wallapa Choeibuakaew, Rina Yuniana

Jurnal Keolahragaan

This research aims to produce a model of self-healing with massage therapy and exercise therapy for proper and effective wrist injury for the community to cure wrist injury. This research was a development research with stage: preliminary study and data collection, planning, product draft development, expert validation, product testing, revision and evaluation. The subjects of small-scale test were 5 people, subjects were large-scale test and product effectiveness test was 10 people using minimum sample size formula at FIK UNY Physical Therapy Clinic and Masase Terapi Cedera Olahraga Metode Ali Satia Graha. The instruments used to collect data were expert validation …

Development Of Physical Fitness Test For Mild Intellectual Disabilities Aged 13-15 Years, Sumaryanti Sumaryanti, Sigit Nugroho, Aqim Visalim, Japhet Ndayisenga

Jurnal Keolahragaan

This study aims to compile a physical fitness test for mild intellectual disability, test the suitability of the test in terms of suitability, convenience, and safety. The developed tests consist of a bench up and down test, a lying down test, a sitting test and a body mass index test. The stages of development carried out include planning stage, preparation stage, trial, evaluation and revision, and final product. The experimental subjects in this study were children with mild intellectual disabilities aged 13-15 years, totaling 148 people who were divided into limited trial subjects, expanded trial subjects, and validity and reliability …

Interest And Motivation Of Indonesian And Malay Students In The Implementation Of Sports Injury Therapeutic Massage, Ali Satia Graha, Kamal Bin Talib, Rina Yuniana, Martono Martono, Krisnanda Dwi Apriyanto, Satya Perdana

Jurnal Keolahragaan

This study was to find out the impact of interest and motivation of Indonesian and Malay students on implementation of management of minor post-Sports injury therapeutic massage. It was a descriptive-qualitative and descriptive quantitative mixed study with survey method. Conducted in 2021 in the Faculty of Sports Science of Yogyakarta State University. Total participans 68 students involved 50 Indonesian students and 18 Malay students. Used linkert scale instrument with modified questionnaire of interest, motivation and implementation, r-count > r-table (0.235) and alpha chronbach of 0.655. The results of the study showed that: the interest of the students in the management of …

The Effectiveness Of Massage Therapy Combined With Stretching Toward Blood Pressure Of Elderly People With Hypertension, Enggista Hendriko Delano, Wara Kushartanti, Abiyyu Amajida, Muhammad Fatih Humam, Sabda Hussain As Shafi

Jurnal Keolahragaan

The high case of hypertension in the elderly requires curative action. One of the efforts to prevent and treat hypertension is by nonpharmacological methods with massage therapy combined with stretching. This research aimed to discover the effectiveness of massage therapy followed by stretching toward the blood pressure of older people with hypertension. Employing a Quasi Experiment design with one group pretest-posttest, the study involved 25 people who had hypertension With 14 of which were selected using specific criteria. The research used Digital Sphygmomanometer to measure blood pressure. The treatment given to the samples was massage therapy for hypertension with the …

Effect Of Playstation® Vr Sessions On Health-Related Quality Of Life And Motor Function In Stroke Patients Undergoing Inpatient Rehabilitation, Chien-Min Chen, Yi-Ching Huang, Kuan-Yu Kung, Yun-Chien Li, I-Lin Yen, Shih-Che Lin, Chu-Hsu Lin, Chia-Hung Lin

Rehabilitation Practice and Science

Background: Virtual Reality (VR) systems have been introduced for rehabilitation of stroke patients. Existing evidence regarding the effects of fully-immersive commercial games on health-related quality of life (HRQOL) and motor function in stroke patients is limited. Objective: To evaluate the efficacy of seven supplemental PlayStation® VR sessions on the HRQOL and motor function of stroke patients undergoing inpatient rehabilitation during a 16-day study period within the first year after stroke. Methods: A randomized, single-blind clinical trial with parallel groups (VR plus conventional therapy vs. conventional therapy) was carried out. For the assessment of outcome measures, the Stroke Impact Scale (SIS) …

Hypertonic Dextrose Injections For Osteoarthritis, Tai-Yung Yi, Ta-Wei Wu, Kuen-Huei Lin

Rehabilitation Practice and Science

Among the elderly, an increase in the prevalence of certain diseases, such as osteoarthritis, has been observed. Patients with osteoarthritis not only experience discomfort and pain but also have limited range of motion in the joints, which lowers their quality of life. At present, non-drug, drug, and surgical treatment options are available for patients with osteoarthritis; these approaches mainly focus on relieving symptoms and reducing the impact of joint disability. Initially, non-drug therapies, such as those focusing on changing the habits of patients, are usually administered. If the disease remains uncontrolled following non-drug therapy, drugs are administered and/or surgery is …