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Rehabilitation and Therapy Commons™

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Marquette University

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Articles 61 - 90 of 348

Full-Text Articles in Rehabilitation and Therapy

Anodal Contralesional Tdcs Enhances Cst Excitability Bilaterally In An Adolescent With Hemiparetic Cerebral Palsy: A Brief Report, Rodrigo G. Delatorre, Ellen N. Sutter, Samuel Nemanich, Linda E. Krach, Gregg Meekins, Timothy Feyma, Bernadette T. Gillick Apr 2023

Anodal Contralesional Tdcs Enhances Cst Excitability Bilaterally In An Adolescent With Hemiparetic Cerebral Palsy: A Brief Report, Rodrigo G. Delatorre, Ellen N. Sutter, Samuel Nemanich, Linda E. Krach, Gregg Meekins, Timothy Feyma, Bernadette T. Gillick

Occupational Therapy Faculty Research and Publications

Hemiparetic cerebral palsy (HCP), weakness on one side of the body typically caused by perinatal stroke, is characterized by lifelong motor impairments related to alterations in the corticospinal tract (CST). CST reorganization could be a useful biomarker to guide applications of neuromodulatory interventions, such as transcranial direct current stimulation (tDCS), to improve effectiveness of rehabilitation therapies. We evaluated an adolescent with HCP and CST reorganization who demonstrated persistent heightened CST excitability in both upper limbs following anodal contralesional tDCS. Results support further investigation of targeted tDCS as an adjuvant therapy to traditional neurorehabilitation for upper limb function.


Mechanisms Of The Age-Related Power Reduction In The Knee Extensor Muscles Of Men And Women, David Wrucke Apr 2023

Mechanisms Of The Age-Related Power Reduction In The Knee Extensor Muscles Of Men And Women, David Wrucke

Master's Theses (2009 -)

The mechanisms for the loss in limb muscle power output in old (60-79 years) and very old adults (≥80 years) and whether these mechanisms differ between older men and women are not well-understood. The aims of the thesis are to 1) compare peak power output of the knee extensor muscles between young, old, and very old adults and 2) determine the physiological mechanisms for the age-related loss of power in men compared with women. 31 young (22.9±3.0 years, 16 men), 83 old (70.4±4.9 years, 44 men), and 16 very old adults (85.8±4.2 years, 7 men) performed maximal isokinetic contractions at …


Case Studies In Physiology: Male To Female Transgender Swimmer In College Athletics, Jonathon Senefeld, Sandra K. Hunter, Doriane Coleman, Michael J. Joyner Apr 2023

Case Studies In Physiology: Male To Female Transgender Swimmer In College Athletics, Jonathon Senefeld, Sandra K. Hunter, Doriane Coleman, Michael J. Joyner

Exercise Science Faculty Research and Publications

There is current scientific and legal controversy about sports competition eligibility regulations for transgender athletes. In this case study, we quantified performances by an elite, transgender woman (male sex, female gender identity) college swimmer who competed in both the men’s and women’s National Collegiate Athletic Association (NCAA) categories. We also contextualized her performances with respect to world-record performances and contemporary elite college swimmers. These data demonstrate that the declines in freestyle swimming performances of a transgender woman after about 2 yr of reported feminizing gender-affirming hormone treatment (0.5% for the 100 to 7.3% for the 1,650 yard distance) are smaller …


Generalized Joint Hypermobility And Lower Extremity Musculoskeletal Biomechanics In Female Athletes, Christopher F. Geiser Apr 2023

Generalized Joint Hypermobility And Lower Extremity Musculoskeletal Biomechanics In Female Athletes, Christopher F. Geiser

Dissertations (1934 -)

Generalized Joint Hypermobility (GJH), in lay terms being “double-jointed”, affects 5 to 43 percent of the general population. In severe forms, GJH impacts systems across the body, with cardiovascular, ocular, and musculoskeletal effects that can be quite debilitating. Most of the literature examining GJH is in this severely impacted group of people. However less severe forms of GJH are present in the athlete population in the same proportions, and athletes with GJH are more likely to be injured while participating in activities. They also experience greater time-loss injuries while participating in athletic activities. The movement biomechanics of those with severe …


Primary Results Of A Phase-Iii, Randomized Controlled Trial Of The Behavioral Intervention For Increasing Physical Activity In Multiple Sclerosis Project, Robert W. Motl, Ariel Kidwell, Brian M. Sandroff, Lara A. Pilutti, Gary R. Cutter, Roberto Aldunate, Rachel E. Bollaert Mar 2023

Primary Results Of A Phase-Iii, Randomized Controlled Trial Of The Behavioral Intervention For Increasing Physical Activity In Multiple Sclerosis Project, Robert W. Motl, Ariel Kidwell, Brian M. Sandroff, Lara A. Pilutti, Gary R. Cutter, Roberto Aldunate, Rachel E. Bollaert

Exercise Science Faculty Research and Publications

Background

We undertook a phase-III, randomized controlled trial (RCT) that examined the effectiveness of a behavioral intervention based on social cognitive theory (SCT) and delivered through the Internet using e-learning approaches for immediate and sustained increases in physical activity among persons with multiple sclerosis (MS).

Method

The study followed a parallel group RCT design. Persons with MS (N = 318) were randomized into either behavioral intervention (n = 159) or attention/social contact control (n = 159) conditions. The conditions were administered over a 6-month period by persons who were uninvolved in screening, recruitment, random assignment, and outcome …


Preventing Osteoarthritis After An Anterior Cruciate Ligament Injury: An Osteoarthritis Action Alliance Consensus Statement, Jeffrey B. Driban, Heather K. Vincent, Thomas H. Trojian, Kristin R. Ambrose, Shelby Baez, Nicholas Beresic, David J. Berkoff, Leigh F. Callahan, Bruce Cohen, Madison Franek, Yvonne M. Golightly, Matthew Harkey, Christopher M. Kuenze, Mary Catherine Minnig, Ali Mobasheri, Adam Naylor, Connie B. Newman, Darin A. Padua, Brian Pietrosimone, Hayley Root, Daniel Pinto, Matthew Salzler, Laura C. Schmitt, Lynn Snyder-Mackler, Jeffrey B. Taylor, Louise M. Thoma, Kevin R. Vincent, Elizabeth Wellsandt, Monette Williams Mar 2023

Preventing Osteoarthritis After An Anterior Cruciate Ligament Injury: An Osteoarthritis Action Alliance Consensus Statement, Jeffrey B. Driban, Heather K. Vincent, Thomas H. Trojian, Kristin R. Ambrose, Shelby Baez, Nicholas Beresic, David J. Berkoff, Leigh F. Callahan, Bruce Cohen, Madison Franek, Yvonne M. Golightly, Matthew Harkey, Christopher M. Kuenze, Mary Catherine Minnig, Ali Mobasheri, Adam Naylor, Connie B. Newman, Darin A. Padua, Brian Pietrosimone, Hayley Root, Daniel Pinto, Matthew Salzler, Laura C. Schmitt, Lynn Snyder-Mackler, Jeffrey B. Taylor, Louise M. Thoma, Kevin R. Vincent, Elizabeth Wellsandt, Monette Williams

Physical Therapy Faculty Research and Publications

After an anterior cruciate ligament (ACL) injury, people need secondary prevention strategies to identify osteoarthritis at its earliest stages so that interventions can be implemented to halt or slow the progression toward its long-term burden. The Osteoarthritis Action Alliance formed an interdisciplinary Secondary Prevention Task Group to develop a consensus on recommendations to provide clinicians with secondary prevention strategies that are intended to reduce the risk of osteoarthritis after a person has an ACL injury. The group achieved consensus on 15 out of 16 recommendations that address patient education, exercise and rehabilitation, psychological skills training, graded-exposure therapy, cognitive-behavioral counseling (lacked …


Randomized Controlled Trial Of The Behavioral Intervention For Increasing Physical Activity In Multiple Sclerosis Project: Secondary, Patient-Reported Outcomes, Robert W. Motl, Brian M. Sandroff, Lara A. Pilutti, Gary R. Cutter, Roberto Aldunate, Ariel Kidwell, Rachel E. Bollaert Feb 2023

Randomized Controlled Trial Of The Behavioral Intervention For Increasing Physical Activity In Multiple Sclerosis Project: Secondary, Patient-Reported Outcomes, Robert W. Motl, Brian M. Sandroff, Lara A. Pilutti, Gary R. Cutter, Roberto Aldunate, Ariel Kidwell, Rachel E. Bollaert

Exercise Science Faculty Research and Publications

Background

We undertook a randomized controlled trial (RCT) that investigated the effectiveness of a theory-based, Internet-delivered, behavioral intervention focusing on physical activity promotion for immediate and sustained improvements in secondary, patient-reported outcomes (PROs) of function, symptoms, and quality of life (QOL) in multiple sclerosis (MS).

Method

Persons with MS (N = 318) were recruited from throughout the United States and randomized into behavioral intervention (n = 159) or attention/social contact control (n = 159) conditions. The conditions were administered over a 6-month period by persons who were uninvolved in screening, recruitment, random assignment, and outcome assessment. There …


Depression, Anxiety, And Physical Activity In Older Adults With Multiple Sclerosis, Rachel E. Bollaert, C. Danielle Jones, Petra Silic, Robert W. Motl Feb 2023

Depression, Anxiety, And Physical Activity In Older Adults With Multiple Sclerosis, Rachel E. Bollaert, C. Danielle Jones, Petra Silic, Robert W. Motl

Exercise Science Faculty Research and Publications

This study examined levels of depression and anxiety symptoms (Hospital Anxiety and Depression Scale scores), and self-reported (Godin Leisure-Time Exercise Questionnaire), and accelerometer-measured physical activity in older adults with multiple sclerosis (n = 40) compared with age- and sex-matched healthy controls (n = 40). We observed differences in depression, anxiety, and physical activity between groups and further observed that minutes/day of moderate to vigorous physical activity partially accounted for group differences in depression scores. We provide preliminary support for research examining approaches for increasing moderate to vigorous physical activity and possibly reducing depression symptoms in older adults with …


Lived Experiences Of American Adults Who Survive Covid-19: Implications For Physical Activity And Interpersonal Stress, Linda B. Piacentine, Hannah C. Barbosa, Kristin Haglund, Lauren Opielinski, Sandra K. Hunter, Paula E. Papanek, Marie K. Hoeger Bement, Norah L. Johnson Jan 2023

Lived Experiences Of American Adults Who Survive Covid-19: Implications For Physical Activity And Interpersonal Stress, Linda B. Piacentine, Hannah C. Barbosa, Kristin Haglund, Lauren Opielinski, Sandra K. Hunter, Paula E. Papanek, Marie K. Hoeger Bement, Norah L. Johnson

College of Nursing Faculty Research and Publications

Introduction: The cumulative number of COVID-19 cases has surpassed 579 million globally. Symptoms during and after COVID-19 infection vary from mild cold symptoms to severe multisystem illness. Given the wide range of symptom presentations and complications post COVID-19, the purpose of this study was to describe the lived experience of American adults surviving COVID-19.

Method: This study employed an exploratory qualitative description design. Semi-structured interviews were conducted with a sample of 35 individuals, [white (94%), female (71%), mean age = 43.7 years], with proximity to a university in an urban Midwest American city. Interviews occurred between May and …


From The Editor, Sandra K. Hunter Jan 2023

From The Editor, Sandra K. Hunter

Exercise Science Faculty Research and Publications

No abstract provided.


“It’S About Being Healthy”; A Novel Approach To The Socio-Ecological Model Using Family Perspectives Within The Latinx Community, Bethany Korom, Meghan Malloy, Caroline Remmers, Mari Cevilla, Kelly Dione, Paula E. Papanek, Jeffrey Condit, David Nelson Jan 2023

“It’S About Being Healthy”; A Novel Approach To The Socio-Ecological Model Using Family Perspectives Within The Latinx Community, Bethany Korom, Meghan Malloy, Caroline Remmers, Mari Cevilla, Kelly Dione, Paula E. Papanek, Jeffrey Condit, David Nelson

Exercise Science Faculty Research and Publications

Background

The Latinx community is at risk for obesity, type 2 diabetes, and other chronic illnesses. Culturally appropriate, community facing physical activity (P.A.) and nutrition programs may provide the basis for families to improve their health status. Our objectives are as follows: 1. To investigate synergistic factors within this type of program that play a role in creating an environment for participants to learn and practice healthy behaviors. 2. To apply factors into a novel model of components that support health and wellness. 3. To design an intervention for future implementation and evaluation.

Methods

A two-year P.A. and nutrition program, …


Cost-Effectiveness Analysis Of Overground Robotic Training Versus Conventional Locomotor Training In People With Spinal Cord Injury, Daniel Pinto, Allen W. Heinemann, Shuo-Hsiu Chang, Susan Charlifue, Edelle C. Field-Fote, Catherine L. Furbish, Arun Jayaraman, Candy Tefertiller, Heather B. Taylor, Dustin D. French Jan 2023

Cost-Effectiveness Analysis Of Overground Robotic Training Versus Conventional Locomotor Training In People With Spinal Cord Injury, Daniel Pinto, Allen W. Heinemann, Shuo-Hsiu Chang, Susan Charlifue, Edelle C. Field-Fote, Catherine L. Furbish, Arun Jayaraman, Candy Tefertiller, Heather B. Taylor, Dustin D. French

Physical Therapy Faculty Research and Publications

Background

Few, if any estimates of cost-effectiveness for locomotor training strategies following spinal cord injury (SCI) are available. The purpose of this study was to estimate the cost-effectiveness of locomotor training strategies following spinal cord injury (overground robotic locomotor training versus conventional locomotor training) by injury status (complete versus incomplete) using a practice-based cohort.

Methods

A probabilistic cost-effectiveness analysis was conducted using a prospective, practice-based cohort from four participating Spinal Cord Injury Model System sites. Conventional locomotor training strategies (conventional training) were compared to overground robotic locomotor training (overground robotic training). Conventional locomotor training included treadmill-based training with body weight …


Effect Of Chronically Suppressed Plasma Angiotensin Ii On Regulation Of The Cyp4a/20-Hete Pathway In The Dahl Salt-Sensitive Rat, Kathleen M. Lukaszewicz, John R. Falck, Julian H. Lombard Jan 2023

Effect Of Chronically Suppressed Plasma Angiotensin Ii On Regulation Of The Cyp4a/20-Hete Pathway In The Dahl Salt-Sensitive Rat, Kathleen M. Lukaszewicz, John R. Falck, Julian H. Lombard

Physical Therapy Faculty Research and Publications

In Dahl salt-sensitive (SS) rats, impaired vascular relaxation can be restored by: (1) minipump infusion of a low (sub-pressor) dose of angiotensin II (ANG II) to restore physiological levels of plasma ANG II, (2) inhibition of 20-HETE production, and (3) introgression of a normally functioning renin allele from the Brown Norway rat (SS-13BN consomic rat). Unlike SS rats, SS-13BN rats have normal levels of ANG II on a normal-salt diet and suppressed ANG II on a high-salt (HS) diet. This study tested whether chronically low ANG II levels in SS rats upregulate cytochrome P450-4A (CYP4A) increasing the production …


Prehabilitation For Total Knee Or Total Hip Arthroplasty: A Systematic Review, Kristin J. Konnyu, Louise M. Thoma, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Daniel Pinto, Ethan M. Balk Jan 2023

Prehabilitation For Total Knee Or Total Hip Arthroplasty: A Systematic Review, Kristin J. Konnyu, Louise M. Thoma, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Daniel Pinto, Ethan M. Balk

Physical Therapy Faculty Research and Publications

We sought to systematically review the evidence on the benefits and harms of prehabilitation interventions for patients who are scheduled to undergo elective, unilateral total knee arthroplasty or total hip arthroplasty surgery for the treatment of primary osteoarthritis. We searched PubMed, Embase, The Cochrane Central Register of Controlled Trials, CINAHL, PsycINFO, Scopus, and ClinicalTrials.gov from January 1, 2005, through May 3, 2021. We selected for inclusion randomized controlled trials and adequately adjusted nonrandomized comparative studies of prehabilitation programs reporting performance-based, patient-reported, or healthcare utilization outcomes. Three researchers extracted study data and assessed risk of bias, verified by an independent researcher. …


Neural And Muscular Contributions To The Age-Related Loss In Power Of The Knee Extensors In Men And Women, David Wrucke, Andrew Kuplic, Mitchell Adam, Sandra K. Hunter, Christopher W. Sundberg Jan 2023

Neural And Muscular Contributions To The Age-Related Loss In Power Of The Knee Extensors In Men And Women, David Wrucke, Andrew Kuplic, Mitchell Adam, Sandra K. Hunter, Christopher W. Sundberg

Exercise Science Faculty Research and Publications

The mechanisms for the loss in limb muscle power in old (60-79 years) and very old (≥80 years) adults and whether the mechanisms differ between men and women are not well-understood. We compared maximal power of the knee extensor muscles between young, old, and very old men and women and identified the neural and muscular factors contributing to the age-related loss of power. 31 young (22.9±3.0 years, 15 women), 83 old (70.4±4.9 years, 39 women), and 16 very old adults (85.8±4.2 years, 9 women) performed maximal isokinetic contractions at 14 different velocities (30- 450°/s) to identify peak power. Voluntary activation …


Who Was Wearing A Mask In 2021? Update On Gender-, Age-, And Location-Related Differences During The Covid-19 Pandemic, Michael H. Haischer, Rachel Beilfuss, Meggie Rose Hart, Lauren Opielinski, Emma Schmit, David Wrucke, Helena Zhao, Toni D. Uhrich, Sandra K. Hunter Jan 2023

Who Was Wearing A Mask In 2021? Update On Gender-, Age-, And Location-Related Differences During The Covid-19 Pandemic, Michael H. Haischer, Rachel Beilfuss, Meggie Rose Hart, Lauren Opielinski, Emma Schmit, David Wrucke, Helena Zhao, Toni D. Uhrich, Sandra K. Hunter

Exercise Science Faculty Research and Publications

Previous observational work from 2020 demonstrated gender-, age-, and location-related differences in mask-wearing behavior, despite the efficacy and public health messaging that emphasized face coverings in combatting the spread of COVID-19. In 2021, COVID-19 vaccinations and a corresponding change in public health policy became new considerations in deciding personal protective behaviors. To provide an update on mask wearers and resistors approximately one year after our initial study, we observed shoppers (n = 6,118) entering retail stores using the same experimental methodology. Approximately 26% of individuals wore a mask. Mask wearing has decreased across demographic groups compared to 2020. Aligning …


Rehabilitation For Total Hip Arthroplasty: A Systematic Review, Kristin J. Konnyu, Daniel Pinto, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Ethan M. Balk, Louise M. Thoma Jan 2023

Rehabilitation For Total Hip Arthroplasty: A Systematic Review, Kristin J. Konnyu, Daniel Pinto, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Ethan M. Balk, Louise M. Thoma

Physical Therapy Faculty Research and Publications

We sought to determine the comparative benefits and harms of rehabilitation interventions for patients who have undergone elective, unilateral THA surgery for the treatment of primary osteoarthritis. We searched PubMed, Embase, The Cochrane Register of Clinical Trials, CINAHL, PsycINFO, Scopus, and ClinicalTrials.gov from January 1, 2005, through May 3, 2021. We included randomized controlled trials and adequately adjusted nonrandomized comparative studies of rehabilitation programs reporting performance-based, patient-reported, or healthcare utilization outcomes. Three researchers extracted study data and assessed risk of bias, verified by an independent researcher. Experts in rehabilitation content and complex interventions independently coded rehabilitation interventions. The team assessed …


Cognitive Challenge As A Probe To Expose Sex- And Age-Related Differences During Static Contractions, Hugo M. Pereira, Sandra K. Hunter Jan 2023

Cognitive Challenge As A Probe To Expose Sex- And Age-Related Differences During Static Contractions, Hugo M. Pereira, Sandra K. Hunter

Exercise Science Faculty Research and Publications

Despite activities of daily living being frequently performed simultaneously with a cognitive task, motor function is often investigated in isolation, which can hinder the applicability of findings. This brief review presents evidence that 1) performing a cognitive challenge simultaneously with a motor task can negatively impact force steadiness and fatigability of limb muscles during a static contraction, 2) the negative impact on old adults (>65 years old), particularly older women is greater than young when a cognitive challenge is simultaneously performed with a static motor task, 3) age-related mechanisms potentially explain impairments in motor performance in the presence of …


Long-Term Function, Body Composition And Cardiometabolic Health In Midlife Former Athletes: A Scoping Review, Jena Heck Street, Zebadiah P. Boos, Alissa V. Fial, Shannon L. Lennon, Carolyn S. Smith, Seth A. Creasy, Sandra K. Hunter, William B. Farquhar, Jacob J. Capin Jan 2023

Long-Term Function, Body Composition And Cardiometabolic Health In Midlife Former Athletes: A Scoping Review, Jena Heck Street, Zebadiah P. Boos, Alissa V. Fial, Shannon L. Lennon, Carolyn S. Smith, Seth A. Creasy, Sandra K. Hunter, William B. Farquhar, Jacob J. Capin

Physical Therapy Faculty Research and Publications

While sports medicine has traditionally focused on recovering from injury and returning athletes to sport safely after injury, there is a growing interest in the long-term health of athletes. The purpose of this scoping review was to (1) summarise the literature (methodologies and findings) on physical function, body composition and cardiometabolic health in midlife (age 40–65 years) former competitive athletes compared with non-athlete controls, (2) identify areas for future study in long-term health in athletes and (3) determine outcomes that could be evaluated in a future systematic review(s). We searched PubMed, CINAHL, Web of Science and SPORTDiscus for studies published …


Patellofemoral Contact Forces And Knee Gait Mechanics 3 Months After Acl Reconstruction Are Associated With Cartilage Degradation 24 Months After Surgery, J. R. Williams, Kelsey Neal, Abdulmajeed Alfayyadh, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Lynn Snyder-Mackler, Thomas S. Buchanan Jan 2023

Patellofemoral Contact Forces And Knee Gait Mechanics 3 Months After Acl Reconstruction Are Associated With Cartilage Degradation 24 Months After Surgery, J. R. Williams, Kelsey Neal, Abdulmajeed Alfayyadh, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Lynn Snyder-Mackler, Thomas S. Buchanan

Physical Therapy Faculty Research and Publications

Objective: Evaluate patellofemoral cartilage health, as assessed by quantitative magnetic resonance imaging (qMRI) T2 relaxation times, 24-months after ACL reconstruction (ACLR) and determine if they were associated with patellofemoral contact forces and knee mechanics during gait 3 months after surgery.

Design: Thirty individuals completed motion analysis during overground walking at a self-selected speed 3 months after ACLR. An EMG-driven neuromusculoskeletal model was used to determine muscle forces, which were then used in a previously described model to estimate patellofemoral contact forces. Biomechanical variables of interest included peak patellofemoral contact force, peak knee flexion angle and moment, and walking speed. …


Using Wearable Technology To Quantify Physical Activity Recovery: Secondary Report From The After (App-Facilitated Tele-Rehabilitation) Program For Covid-19 Survivors Randomized Study, Laura Churchill, Mary Morrow, Jacob J. Capin, Sarah Jolley, Kristine Hare, Samantha Mawhinney, Jennifer E. Stevens-Lapsley, Kristine M. Erlandson Jan 2023

Using Wearable Technology To Quantify Physical Activity Recovery: Secondary Report From The After (App-Facilitated Tele-Rehabilitation) Program For Covid-19 Survivors Randomized Study, Laura Churchill, Mary Morrow, Jacob J. Capin, Sarah Jolley, Kristine Hare, Samantha Mawhinney, Jennifer E. Stevens-Lapsley, Kristine M. Erlandson

Physical Therapy Faculty Research and Publications

Background: Knowledge on physical activity recovery after COVID-19 survival is limited. The AFTER (App-Facilitated Tele-Rehabilitation) program for COVID-19 survivors randomized participants, following hospital discharge, to either education and unstructured physical activity or a telerehabilitation program. Step count data were collected as a secondary outcome, and we found no significant differences in total step count trajectories between groups at 6 weeks. Further step count data were not analyzed.

Objective: The purpose of this analysis was to examine step count trajectories and correlates among all participants (combined into a single group) across the 12-week study period.

Methods: Linear mixed …


Rehabilitation For Total Knee Arthroplasty: A Systematic Review, Kristin J. Konnyu, Louise M. Thoma, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Ethan M. Balk, Daniel Pinto Jan 2023

Rehabilitation For Total Knee Arthroplasty: A Systematic Review, Kristin J. Konnyu, Louise M. Thoma, Wangnan Cao, Roy K. Aaron, Orestis A. Panagiotou, Monika Reddy Bhuma, Gaelen P. Adam, Ethan M. Balk, Daniel Pinto

Physical Therapy Faculty Research and Publications

We sought to determine the comparative benefit and harm of rehabilitation interventions for patients who have undergone elective, unilateral total knee arthroplasty for the treatment of primary osteoarthritis. We searched PubMed, Embase, The Cochrane Register of Clinical Trials, CINAHL, PsycINFO, Scopus, and ClinicalTrials.gov from January 1, 2005, through May 3, 2021. We included randomized controlled trials and adequately adjusted nonrandomized comparative studies of rehabilitation programs reporting performance-based, patient-reported, or healthcare utilization outcomes. Three researchers extracted study data and assessed risk of bias, verified by an independent researcher. The team assessed strength of evidence. Evidence from 53 studies randomized controlled trials …


A Complete Workflow For High Throughput Human Single Skeletal Muscle Fiber Proteomics, Amanda Momenzadeh, Yuming Jiang, Simion Kreimer, Laura E. Teigen, Carlos S. Zepeda, Ali Haghani, Mitra Mastali, Yang Song, Alexandre Hutton, Sarah J. Parker, Jennifer E. Van Eyk, Christopher W. Sundberg, Jesse G. Meyer Jan 2023

A Complete Workflow For High Throughput Human Single Skeletal Muscle Fiber Proteomics, Amanda Momenzadeh, Yuming Jiang, Simion Kreimer, Laura E. Teigen, Carlos S. Zepeda, Ali Haghani, Mitra Mastali, Yang Song, Alexandre Hutton, Sarah J. Parker, Jennifer E. Van Eyk, Christopher W. Sundberg, Jesse G. Meyer

Physical Therapy Faculty Research and Publications

Skeletal muscle is a major regulatory tissue of whole-body metabolism and is composed of a diverse mixture of cell (fiber) types. Aging and several diseases differentially affect the various fiber types, and therefore, investigating the changes in the proteome in a fiber-type specific manner is essential. Recent breakthroughs in isolated single muscle fiber proteomics have started to reveal heterogeneity among fibers. However, existing procedures are slow and laborious, requiring 2 h of mass spectrometry time per single muscle fiber; 50 fibers would take approximately 4 days to analyze. Thus, to capture the high variability in fibers both within and between …


Moderate-To-Vigorous Physical Activity Is Related With Retinal Neuronal And Axonal Integrity In Persons With Multiple Sclerosis, Jeongwoon Kim, Rachel E. Bollaert, Jonathan Cerna, Brynn C. Adamson, Connor M. Robbs, Naiman A. Khan, Robert W. Motl Dec 2022

Moderate-To-Vigorous Physical Activity Is Related With Retinal Neuronal And Axonal Integrity In Persons With Multiple Sclerosis, Jeongwoon Kim, Rachel E. Bollaert, Jonathan Cerna, Brynn C. Adamson, Connor M. Robbs, Naiman A. Khan, Robert W. Motl

Exercise Science Faculty Research and Publications

Background

Moderate-to-vigorous physical activity (MVPA) may confer benefits for axonal and/or neuronal integrity in adults with multiple sclerosis (MS).

Purpose

Examine the association between device-measured MVPA with optical coherence tomography (OCT) metrics of retinal nerve fiber layer (RNFL) thickness and total macular volume (TMV) in persons with and without MS.

Methods

Adults with MS (N = 41), along with sex-matched healthy control (HC) participants (N = 79), underwent measurements of retinal morphology via OCT and wore an accelerometer for a period of 7 days as a measure of MVPA.

Results

Persons with MS had significantly lower MVPA, RNFL thickness, and …


Bone–Patellar Tendon–Bone Autograft Harvest Prolongs Extensor Latency During Gait 2 Yr After Aclr, Naoaki Ito, Jacob J. Capin, Ashutosh Khandha, Thomas S. Buchanan, Karin Grävare Silbernagel, Lynn Snyder-Mackler Dec 2022

Bone–Patellar Tendon–Bone Autograft Harvest Prolongs Extensor Latency During Gait 2 Yr After Aclr, Naoaki Ito, Jacob J. Capin, Ashutosh Khandha, Thomas S. Buchanan, Karin Grävare Silbernagel, Lynn Snyder-Mackler

Physical Therapy Faculty Research and Publications

Purpose

Bone–patellar tendon–bone (BPTB) graft harvest for anterior cruciate ligament reconstruction alters patellar tendon properties, which inflict poor quadriceps neuromuscular function. BPTB autografts are associated with higher rates of posttraumatic osteoarthritis, which in turn is associated with pathological gait. The purpose of this study was to investigate the latency between the time of peak quadriceps activity and the peak knee flexion moment during gait, between those with BPTB grafts (n = 23) and other graft types (hamstring autograft or allografts, n = 54), 5 ± 2 months and 2 yr (25 ± 3 months) after anterior cruciate ligament reconstruction. …


Single Muscle Fibre Contractile Function With Ageing, Gregory J. Grosicki, Carlos S. Zepeda, Christopher W. Sundberg Dec 2022

Single Muscle Fibre Contractile Function With Ageing, Gregory J. Grosicki, Carlos S. Zepeda, Christopher W. Sundberg

Physical Therapy Faculty Research and Publications

Ageing is accompanied by decrements in the size and function of skeletal muscle that compromise independence and quality of life in older adults. Developing therapeutic strategies to ameliorate these changes is critical but requires an in-depth mechanistic understanding of the underlying physiology. Over the past 25 years, studies on the contractile mechanics of isolated human muscle fibres have been instrumental in facilitating our understanding of the cellular mechanisms contributing to age-related skeletal muscle dysfunction. The purpose of this review is to characterize the changes that occur in single muscle fibre size and contractile function with ageing and identify key areas …


Knee Joint Biomechanics During Gait Improve From 3 To 6 Months After Anterior Cruciate Ligament Reconstruction, Kelsey Neal, Jack R. Williams, Abdulmajeed Alfayyadh, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Lynn Snyder-Mackler, Thomas S. Buchanan Sep 2022

Knee Joint Biomechanics During Gait Improve From 3 To 6 Months After Anterior Cruciate Ligament Reconstruction, Kelsey Neal, Jack R. Williams, Abdulmajeed Alfayyadh, Jacob J. Capin, Ashutosh Khandha, Kurt Manal, Lynn Snyder-Mackler, Thomas S. Buchanan

Physical Therapy Faculty Research and Publications

Gait alterations after anterior cruciate ligament reconstruction (ACLR) are commonly reported and have been linked to posttraumatic osteoarthritis development. While knee gait alterations have been studied at several time points after ACLR, little is known about how these biomechanical variables change earlier than 6 months after surgery, nor is much known about how they differ over the entire stance phase of gait. The purpose of this study was to examine knee gait biomechanical variables over their entire movement pattern through stance at both 3 and 6 months after ACLR and to study the progression of interlimb asymmetry between the two …


Role Of Physical Therapists In The Management Of Individuals At Risk For Or Diagnosed With Venous Thromboembolism: Evidence-Based Clinical Practice Guideline 2022, Ellen Hillegass, Kathleen M. Lukaszewicz, Michael Puthoff Aug 2022

Role Of Physical Therapists In The Management Of Individuals At Risk For Or Diagnosed With Venous Thromboembolism: Evidence-Based Clinical Practice Guideline 2022, Ellen Hillegass, Kathleen M. Lukaszewicz, Michael Puthoff

Physical Therapy Faculty Research and Publications

No matter the practice setting, physical therapists work with patients who are at risk for or who have a history of venous thromboembolism (VTE). In 2016, the first clinical practice guideline (CPG) addressing the physical therapist management of VTE was published with support by the American Physical Therapy Association’s Academy of Cardiovascular and Pulmonary Physical Therapy and Academy of Acute Care, with a primary focus on lower extremity deep vein thrombosis (DVT). This CPG is an update of the 2016 CPG and contains the most current evidence available for the management of patients with lower extremity DVT and new key …


Cost-Effectiveness Of High-Intensity Training Vs Conventional Therapy For Individuals With Subacute Stroke, T. George Hornby, Miriam Rafferty, Daniel Pinto, Dustin D. French, Neil Jordan Jul 2022

Cost-Effectiveness Of High-Intensity Training Vs Conventional Therapy For Individuals With Subacute Stroke, T. George Hornby, Miriam Rafferty, Daniel Pinto, Dustin D. French, Neil Jordan

Physical Therapy Faculty Research and Publications

Objective

This investigation estimated the incremental cost-effectiveness of high-intensity training (HIT) compared with conventional physical therapy in individuals with subacute stroke, based on the additional personnel required to deliver the therapy.

Design

Secondary analysis from a pilot study and subsequent randomized controlled trial.

Setting

Outpatient laboratory setting.

Participants

Data were collected from individuals with locomotor impairments 1-6 months poststroke (N=44) who participated in HIT (n=27) or conventional physical therapy (n=17).

Interventions

Individuals performing HIT practiced walking tasks in variable contexts (stairs, overground, treadmill) while targeting up to 80% maximum heart rate reserve. Individuals performing conventional therapy practiced impairment-based and functional …


Identifying Gait Pathology After Acl Reconstruction Using Temporal Characteristics Of Kinetics And Electromyography, Naoaki Ito, Jacob J. Capin, Ashutosh Khandha, Thomas S. Buchanan, Lynn Snyder-Mackler Jun 2022

Identifying Gait Pathology After Acl Reconstruction Using Temporal Characteristics Of Kinetics And Electromyography, Naoaki Ito, Jacob J. Capin, Ashutosh Khandha, Thomas S. Buchanan, Lynn Snyder-Mackler

Physical Therapy Faculty Research and Publications

Purpose

Asymmetrical gait mechanics after anterior cruciate ligament reconstruction (ACLR) are associated with the development of posttraumatic knee osteoarthritis. Current measures of gait mechanics have focused heavily on peak magnitudes of knee kinematics, kinetics, and joint contact forces but have seldom considered the rate of knee loading, cumulative knee load, or the timing of motor input surrounding peaks. The purpose of this study was to introduce and describe novel metrics of gait using temporal characteristics of kinetics and EMG to identify neuromuscular deficits of the quadriceps in patients after ACLR.

Methods

Gait mechanics were assessed 6 months (n = …