Rehabilitation and Therapy Commons^™

Ventilatory Phenotypes Among Four Strains Of Adult Rats., Matthew Hodges, Hubert Forster, Paula E. Papanek, Melinda R. Dwinell, Genevieve E. Hogan

Exercise Science Faculty Research and Publications

Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-hooded Hypertensive (FHH: n = 27), and outbred Sprague-Dawley rats (SD; n = 37). We measured eupneic (room air) breathing and the ventilatory responses to hypoxia (12% O₂-88% N₂), hypercapnia (7% CO₂), and two levels of submaximal exercise. Primary strain differences were between BN and the other strains. BN rats had a …

5 Questions–And Answers–About Negative Pressure Wound Therapy, Luther C. Kloth

Physical Therapy Faculty Research and Publications

No abstract provided.

Angiotensin Ii And Vegf Are Involved In Angiogenesis Induced By Short-Term Exercise Training, Sandra L. Amaral, Paula E. Papanek, Andrew S. Greene

Exercise Science Faculty Research and Publications

Results from our laboratory have suggested a pathway involving angiotensin II type 1 (AT₁) receptors and vascular endothelial growth factor (VEGF) in angiogenesis induced by electrical stimulation. The present study investigated if similar mechanisms underlie the angiogenesis induced by short-term exercise training. Seven days before training and throughout the training period, male Sprague-Dawley rats received either captopril or losartan in their drinking water. Rats underwent a 3-day treadmill training protocol. The tibialis anterior and gastrocnemius muscles were harvested under anesthesia and lightly fixed in formalin (vessel density) or frozen in liquid nitrogen (VEGF expression). In controls, treadmill training …

5 Questions–And Answers–About Electrical Stimulation, Luther C. Kloth

Physical Therapy Faculty Research and Publications

No abstract provided.

Effect Of Setup Configurations Of Split Computer Keyboards On Wrist Angle, Richard W. Marklin, Guy G. Simoneau

Physical Therapy Faculty Research and Publications

Alternative computer keyboards whose halves can be slanted toward each other can reduce a risk factor (ulnar deviation) for work-related musculoskeletal disorders (WMSDs) affecting the upper limbs. Two questions that computer keyboard operators face when using keyboards that can be separated into halves (split keyboards) are: (1) At what angle should the keyboard halves be opened? and (2) At what distance apart should the keyboard halves be placed? The objective of this study was to investigate the effects of the opening angle and separation distance between halves of a split keyboard on wrist ulnar deviation and typing efficiency. Methods. Eleven …

Walker-Assisted Gait In Rehabilitation: A Study Of Biomechanics And Instrumentation, Rebecca Ann Bachschmidt, Gerald F. Harris, Guy G. Simoneau

Physical Therapy Faculty Research and Publications

While walkers are commonly prescribed to improve patient stability and ambulatory ability, quantitative study of the biomechanical and functional requirements for effective walker use is limited. To date no one has addressed the changes in upper extremity kinetics that occur with the use of a standard walker, which was the objective of this study. A strain gauge-based walker instrumentation system was developed for the six degree-of-freedom measurement of resultant subject hand loads. The walker dynamometer was integrated with an upper extremity biomechanical model. Preliminary system data were collected for seven healthy, right-handed young adults following informed consent. Bilateral upper extremity …

Effects Of Electrical Stimulation On Wound Closure In Mice With Experimental Diabetes Mellitus, Habiba A. Thawer, Pamela E. Houghton, Luther Kloth, Anna Butryn

Physical Therapy Faculty Research and Publications

The purpose of the present study was to examine the effect of electrical stimulation (ES) on the closure of full-thickness excisional wounds in mice with type-1 experimental diabetes mellitus (DM). Alloxon monohydrate (100mg/kg) was used to induce experimental DM in mole CD-1 mice (n = 88). Full-thickness skin excisions (1cm²) in diabetic (urine glucose > 0) and non-diabetic (urine glucose = 0) mice were administered 1, 3, or 5 treatments of ES (200μs, 200 Hz) for 15 minutes, at 0 (sham), 5, 10, or 12.5 volts. Alloxon injection resulted in a positive urine glucose test in 48 mice yielding …

Whole Body Momentum During Gait: A Preliminary Study Of Non-Fallers And Frequent Fallers, Guy G. Simoneau, David E. Krebs

Physical Therapy Faculty Research and Publications

The importance of momentum in compensating for elderly individua ls ' strength deficits to achieve activities of daily living. such as rising from a chair ha.!o been demonstrated in earlier studies. Here we present a case control study of three healthy "non-fallers" and two "frequent fallers," All 5 elders were community-living and were tested in the gai l laboratory. A four-camera Selspot system was used to obtain whole-body momentum from an 11-segment kinematic model. Ground reaction forces and kinematics were used 10 calculate lower extremity join! moments. With the exception of the whole-body's angular momentum about the vertical axis, linear …

Gender-Specific Protection From Microvessel Rarefaction In Female Hypertensive Rats, Paula E. Papanek, Mark J. Rieder, Julian H. Lombard, Andrew S. Greene

Exercise Science Faculty Research and Publications

Epidemiologic studies reveal that women have a significantly lower age-adjusted morbidity and mortality from cardiovascular disease than men, suggesting that gender is a cardiovascular disease risk factor. The mechanism of the “gender protection” is unknown. In this study, we investigated the microvascular remodeling in reduced renal mass plus a high salt (4.0% NaCl) diet model of hypertension (RRM + HS). We hypothesized that women would be protected from the increase in blood pressure and from the microvascular rarefaction associated with RRM + HS hypertension. Studies were designed to determine whether female rats were less susceptible to changes in microvessel density …

Changes In Ankle Joint Proprioception Resulting From Strips Of Athletic Tape Applied Over The Skin, Guy G. Simoneau, Rebecca M. Degner, Cindi A. Kramper, Kent H. Kittleson

Physical Therapy Faculty Research and Publications

Athletic trainers, physical therapists, and other rehabilitation professionals stress the importance of proprioceptive reeducation during the rehabilitation process following an injury." 2 It is believed that an injury such as an inversion ankle sprain, for example, results in a reduction of proprioceptive function that may lead to future reinjuries. 3 One suggested palliative method to supplement a deficit in proprioceptive function at the ankle is the use of external support such as taping and braces.47 The tape or brace is believed to provide increased mechanical support as well as increased proprioception.

In Vitro Effects Of Two Silver Electrodes On Select Wound Pathogens, Linda Jean Laatsch-Lybeck, Poh Chye Ong, Luther C. Kloth

Physical Therapy Faculty Research and Publications

The use of electrical current to promote wound healing is well documented. However, little is understood about the effects of micro-amperage direct current (μADC) on growth of wound pathogens. The purpose of this project was to investigate the antibacterial effects of a silver wire/silver nylon electrode carrying μADC in vitro on several Gram positive and Gram negative bacteria. The current was delivered via silver wire and silver nylon electrodes at an amplitude of 100 μA for a 30-minute duration in an in vitro system. Results demonstrated that only silver wire carrying current inhibited bacterial growth around …

Antibacterial Effects Of A Silver Electrode Carrying Microamperage Direct Current In Vitro, Poh Chye Young, Luther C. Kloth, Linda Jean Laatsch-Lybeck

Physical Therapy Faculty Research and Publications

Currently, electrical stimulation is an accepted method used clinically to promote chronic wound healing. A literature review revealed that similar therapeutic current has been shown to suppress growth of common wound pathogens in vitro and in vivo. To date, little has been reported on the factors contributing to the antibacterial effects of microamperage direct current (μADC) stimulation. The purpose of this project was to investigate the role of electric field strength, current density, pH, and type of electrode used in vitro, to gain a better understanding of how these factors contribute to inhibiting growth of select wound pathogens. …

Posture And Gait In Patients With Diabetic Distal Symmetrical Polyneuropathy, Guy G. Simoneau, Peter R. Cavanagh, Jan S. Ulbrecht

Physical Therapy Faculty Research and Publications

No abstract provided.

Improved Healing Of Pressure Ulcers Using Dermapulse, A New Electrical Stimulation Device, Gary D. Gentzkow, Sheldon V. Pollack, Luther C. Kloth, Harrison A. Stubbs

Physical Therapy Faculty Research and Publications

A double-blind, clinical study of pulsed electrical stimulation using the Dermapulse® device was carried out on 40 pressure ulcers, randomized to receive either active (stim) or sham treatment.

Electrodes were placed over saline-moistened gauze on the ulcers. An electrical current of 35mA was delivered to the wound tissues at a frequency of 128 pulses per second. Polarity was negative until the wound debrided, then alternated from .positive to negative every three days. Ulcers were treated for 30 minutes twice daily for four weeks, after which sham patients could cross over to active treatment, and stim patients could continue active treatment. …

Chronic Dermal Ulcer Healing Enhanced With Monophasic Pulsed Electrical Stimulation, Jeffery A. Feedar, Luther C. Kloth, Gary D. Gentzkow

Physical Therapy Faculty Research and Publications

The purposes of this randomized, double-blind, multicenter study were to compare healing of chronic dermal ulcers treated with pulsed electrical stimulation with healing of similar wounds treated with sham electrical stimulation and to evaluate patient tolerance to the therapeutic protocol. Forty-seven patients, aged 29 to 91 years, with 50 stage II, III, and IV ulcers were randomly assigned to either a treatment group (n=26) or a control (sham treatment) group (n=24). Treated wounds received 30 minutes of pulsed cathodal electrical stimulation twice daily at a pulse frequency of 128 pulses per second (pps) and a peak amplitude of 29.2 mA …

Acceleration Of Wound Healing With High Voltage, Monophasic, Pulsed Current, Luther C. Kloth, Jeffery A. Feedar

Physical Therapy Faculty Research and Publications

The purpose of this study was to determine whether high voltage electrical stimulation accelerates the rate of healing of dermal ulcers. Sixteen patients with stage IV decubitus ulcers, ranging in age from 20 to 89 years, participated in the study. The patients were assigned randomly to either a Treatment Group (n = 9) or a Control Group (n = 7). Patients in the Treatment Group received daily electrical stimulation from a commercial high voltage generator. Patients in the Control Group had the electrodes applied daily but received no stimulation. The ulcers of patients in the Treatment Group healed at a …

Supervised Versus Independent Student Laboratories, Luther C. Kloth, Mary Ann Morrison

Physical Therapy Faculty Research and Publications

The purpose of this study was to determine if classroom laboratory time could be reduced in a basic physical agents course. Fifty-seven junior physical therapy students were randomly assigned to three laboratory sections. All students received identical lectures, demonstrations, course materials, and laboratory manuals. The control group, Section 1, received supervision and assistance during laboratory practice. Students in Section 2 and Section 3 worked independent of instructor supervision but could receive assistance from the instructor in an adjacent room. Students in Section 2 were provided with feedback following periodic assessment by the instructor. Attitudinal questionnaire responses indicated that the students …

Effect Of Age On Hemodynamic And Metabolic Response To Static Exercise, Daniel J. Mcdermott, William J. Stekiel, Joseph J. Barboriak, Luther C. Kloth, James J. Smith

Physical Therapy Faculty Research and Publications

Static muscle exercise tests consisting of one-third maximum voluntary contraction of the forearm for 5 min was carried out in a group of older (mean age 46.8 yr) and younger men (mean age 25.3 yr). The mean hemodynamic changes in the two groups were quite comparable with increases in heart rate (31.3 and 38.4 beats/min), systolic pressure (74.3 and 63.2 mmHg), and diastolic pressure (58.1 and 47.3 mmHg) in older and younger groups, respectively. There was a prompt postexercise increase in mean total plasma catecholamine level in older males with a rapid decline over the next 15 min; the increase …