Women's Health Commons^™

Risk Factors For Secondary Infertility Among Women In Karachi, Pakistan., Neelofar Sami, Tazeen S. Ali, Saba Wasim, Sarah Saleem

Community Health Sciences

Background: Secondary infertility in developing countries is mostly attributable to blockage of the fallopian tubes due to adhesions caused by reproductive tract infections. There is a dearth of information on the prevalence and causes of secondary infertility from Pakistan. This paper presents results on factors associated with secondary infertility among married women in Karachi, Pakistan. Methods: A matched case-control study was conducted. Cases were women aged 15-35 years with history of at least one previous conception and currently seeking treatment for secondary infertility. Controls were women residing in the neighborhood of cases with at least one live birth and not …

Rates Of Iucd Discontinuation And Its Associated Factors Among The Clients Of A Social Franchising Network In Pakistan, Syed Khurram Azmat, Babar Tasneem Shaikh, Waqas Hameed, Mohsina Bilgrami, Ghulam Mustafa, Muhammad Ali, Muhammad Ishaque, Wajahat Hussain, Aftab Ahmed

Community Health Sciences

Background: Modern Intrauterine contraceptive device (IUCD) is very safe, highly effective reversible and inexpensive family planning method which offers 5-10 years of protection against pregnancy. The contraceptive use in Pakistan has been merely 30% for over a decade with IUCD being the least used method. Higher discontinuation rates are documented in developing countries; however no such data is available for Pakistan. Marie Stopes Society (MSS) established a social franchise outlets network branded as 'SURAJ' (Sun) in Pakistan to provide quality family planning services. This study attempts to determine IUCD discontinuation rates and its associated risk factors. Using a semi-structured questionnaire, …

Barriers And Perceptions Regarding Different Contraceptives And Family Planning Practices Amongst Men And Women Of Reproductive Age In Rural Pakistan: A Qualitative Study, Syed Khurram Azmat, Ghulam Mustafa, Waqas Hameed, Muhammad Ali, Aftab Ahmed, Mohsina Bilgrami

Community Health Sciences

Background: Pakistan ranks as one of the most poorest and most populous in the world with poor reproductive health indicators. This study helps in understanding barriers and perceptions regarding Family Planning (FP), modern contraception, quality of care and free of charge FP services amongst men and women in rural Pakistan.
Methods: Employing purposive sampling and Focus Group Discussion (FGD) technique, this qualitative study was conducted with men and women of reproductive age in Pakistan. A total of eight FGDs were conducted in Sindh and Punjab provinces. Being descriptive in nature, the study provided a thematic analysis of the relevant health …

Risk Factors For Depression Among Married Women Belonging To Higher And Lower Socioeconomic Status In Karachi, Pakistan, Saima Zainab, Zafar Fatmi, Ambreen Kazi

Community Health Sciences

OBJECTIVES: To determine the risk factors for depression among married women belonging to low and high socioeconomic status in Karachi.METHODS: The study design was cross-sectional. The data was collected from 128 adult married women during July to September 2005. The women were selected from different socioeconomic classes from five hospitals/institutes in Karachi. The Centre for Epidemiology Studies-Depression (CES-D) scale was used to screen the subjects for depression and a structured questionnaire was used to identify the factors for depression.RESULT: According to the CES-D scale, 65% of the study population was found to be depressed. Among the women from high socioeconomic …

The Cyclin-Like Protein Spy1/Ringo Promotes Mammary Transformation And Is Elevated In Human Breast Cancer, Mohammad Al Sorkhy, Rosa-Maria Ferraiuolo, Espanta Jalili, Agnes Malysa, Andreea R. Fratiloiu, Bonnie F. Sloane, Lisa A. Porter

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Spy1 is a novel 'cyclin-like' activator of the G1/S transition capable of enhancing cell proliferation as well as inhibiting apoptosis. Spy1 protein levels are tightly regulated during normal mammary development and forced overexpression in mammary mouse models accelerates mammary tumorigenesis.

Methods

Using human tissue samples, cell culture models and in vivo analysis we study the implications of Spy1 as a mediator of mammary transformation and breast cancer proliferation.

Results

We demonstrate that this protein can facilitate transformation in a manner dependent upon the activation of the G2/M Cdk, Cdk1, and the subsequent inhibition of the anti-apoptotic regulator FOXO1. …

Erlin2 Promotes Breast Cancer Cell Survival By Modulating Endoplasmic Reticulum Stress Pathways, Guohui Wang, Gang Liu, Xiaogang Wang, Seema Sethi, Rouba Ali-Fehmi, Judith Abrams, Ze Zheng, Kezhong Zhang, Stephen Ethier, Zeng-Quan Yang

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Amplification of the 8p11-12 region has been found in approximately 15% of human breast cancer and is associated with poor prognosis. Previous genomic analysis has led us to identify the endoplasmic reticulum (ER) lipid raft-associated 2 (ERLIN2) gene as one of the candidate oncogenes within the 8p11-12 amplicon in human breast cancer, particularly in the luminal subtype. ERLIN2, an ER membrane protein, has recently been identified as a novel mediator of ER-associated degradation. Yet, the biological roles of ERLIN2 and molecular mechanisms by which ERLIN2 coordinates ER pathways in breast carcinogenesis remain unclear.

Methods

We established the MCF10A-ERLIN2 …

Nonclinical Development Needs And Regulatory Requirements For Multipurpose Prevention Technologies: A Primer, Joseph W. Romano, Martha Brady, Judy Manning

HIV and AIDS

This summary outlines key development elements that will be necessary for various configurations of multipurpose prevention products for the simultaneous prevention of HIV, sexually transmitted infections, and/or pregnancy.

Shaping The Operations Research Agenda For Antiretroviral-Based Prevention Products For Women: Gels And Rings, Martha Brady, C. Elizabeth Mcgrory

HIV and AIDS

This report summarizes discussions from a two-day international experts consultation meeting in 2012 on preparing for the successful introduction of women-centered antiretroviral-based HIV prevention methods. It examines the limits and expectations of operations research in antiretroviral health technologies.

Perceptions Of Risk Associated With Unintended Pregnancy And Sexually Transmitted Infections Among University Women Attending Minnesota State University, Mankato, Jessica Maria Seide

All Graduate Theses, Dissertations, and Other Capstone Projects

Unintended pregnancies and sexually transmitted infections are preventable, yet there is still a high occurrence of both among university women. This study evaluated perceptions of risk associated with unintended pregnancies and sexually transmitted infections among selected university women aged 18-25. This study identified whether women's perceptions of risk affected their decision to take certain precautions to prevent pregnancies and sexually transmitted infections. This study also examined whether there was a relationship between perceptions of risk associated with unintended pregnancies and perceptions of risk associated with sexually transmitted infections and some of the variables that are associated with that relationship. This …

College Age Female Smokers And The Efficacy Of Smoking Cessation On College Campuses, Gretchen Suzanne Strobel

All Graduate Theses, Dissertations, and Other Capstone Projects

Young females are smoking on campuses in increasing rates in the last two decades. This thesis is secondary data analysis of a primary study with data from 472 female respondents, ages 18 to 24, enrolled or registered for classes at Minnesota State University, Mankato in the Spring, Summer and Fall semester of 2011. This sample included current smokers, former smokers, and nonsmokers. This research study will discuss the relationship between the age one starts smoking and any association with participation in unprotected intercourse and the concomitant use of estrogen containing oral contraceptives. Among the respondents a majority started smoking between …

Mothers' Health And Health Behaviors That Influence Childhod Obesity Maternal Bmi And Infant Feeding Methods, Mohamed Abdullah Alammari

All Graduate Theses, Dissertations, and Other Capstone Projects

The rate of childhood obesity in America continues to climb. Many medical experts believe that childhood obesity can develop as early as prenatal development in the uterus, and infancy. The purpose of this study is to explore the relationships between mothers' health and health behaviors (maternal BMI and infant feeding methods) and childhood obesity. We conducted and analyzed a sample of 307 mothers and their children (307) to examine each mother's maternal BMI and her child or children's BMI. We also examined mothers' feeding methods (bottle vs. breastfeeding).The result of this research did not match with the review of literature. …

Exploration Of Weight Gain In Female Breast Cancer Survivors, Mary Kay Johnson

All Graduate Theses, Dissertations, and Other Capstone Projects

Breast cancer is no longer a guaranteed death sentence. Many women today can look forward to a long and healthy life after treatment for breast cancer. However, weight gain is an ongoing, distressing and common problem for women treated for breast cancer. The primary purpose of this study was to gain knowledge about the phenomena of weight gain in females treated for breast cancer. A descriptive cross-sectional study was conducted in a natural setting. Sample: Electronic medical records for 100 female breast cancer survivors who visited a private suburban medical oncology clinic for treatment and/or on-going follow-up for a breast …

Le Consensus De Bellagio : Recommandations Pour Améliorer L'Accès Aux Méthodes De Contraception Efficaces, Réversibles À Longue Durée D'Action, Population Council

Reproductive Health

Ce communiqué et cette déclaration proposent des recommandations pour améliorer l'accès aux méthodes de contraception efficaces, réversibles à longue durée d'action (LARC) et accélérer les progrès vers la réalisation de l'Objectif du Millénaire pour le développement relatif à l'accès universel aux services de santé reproductive.

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This brief and statement offers recommendations for action to increase access to highly effective, long-acting, reversible contraception (LARCs) and accelerate progress toward meeting the Millennium Development Goal of universal access to reproductive health services.

Attitudes, Beliefs, And Practices Of Providers And Key Opinion Leaders On Emergency Contraception In India, M.E. Khan, Deepthi S. Varma, Isha Bhatnagar, Anvita Dixit, Martha Brady

Reproductive Health

The Population Council undertook this study to assess the knowledge, attitudes, and practices regarding emergency contraception (ECP) among providers in public and private facilities and pharmacies in India. The objectives of the study were to: assess providers' knowledge of ECP's biological mechanism; understand providers' knowledge and attitudes about ECP's safety, effectiveness, and availability as an OTC drug; and identify providers' definitions of “repeated use” and profiling women who are “repeated users” of ECP. This study's findings show that most providers, including doctors and some KOLs, were incorrectly informed about ECP's mechanism of action. Service guidelines are necessary for accurate and …

Expanding Access To Comprehensive Reproductive Health And Hiv Information And Services For Married Adolescent Girls In Nyanza Province, Chi-Chi Undie, Harriet Birungi, Francis Obare, Ben Ochieng, Wilson Liambila, Erick Oweya, Ian Askew, Rob Burnet, Bridget Deacon, Aisha Mohamed

Reproductive Health

The objectives of this operations research study, conducted by the Population Council’s APHIA II Operations Research Project in Kenya, were to: 1) identify and design a set of interventions that promote the uptake of comprehensive reproductive health (RH)/family planning (FP) and HIV prevention services and information among married adolescent girls; and 2) expand access to comprehensive RH/FP and HIV prevention services and information among this population. The study demonstrated that the combined use of interactive media and community health worker visitation, health information provision, and referrals, is an effective means of reinforcing RH/FP and HIV messages, and of increasing access …

Providers' And Key Opinion Leaders' Attitudes, Beliefs, And Practices Regarding Emergency Contraception In Nigeria, Babatunde A.O. Ahonsi, Salisu Mohammed Ishaku, Araoyinbo Idowu, Ayodeji Oginni

Reproductive Health

Despite significant progress in product development, procurement, and distribution in the past few decades, emergency contraception’s (EC) capacity to benefit many women in countries such as Nigeria is hampered by a number of potential barriers, that are not well understood. The Population Council, with support from the International Consortium for Emergency Contraception, documented EC-related knowledge, attitudes, and practices among providers in Nigeria as well as perceptions of key opinion leaders who help shape the policy environment for EC and family planning in general. Findings suggest significant gaps in Nigeria, potentially necessitating continuous training and re-training to help dispel misperceptions and …

Oral Health Knowledge, Attitudes, And Behaviors: Investigation Of An Educational Intervention Strategy With At-Risk Females, Susan Romano Rustvold

Dissertations and Theses

A self-perpetuating cycle of poor health literacy and poor oral health knowledge and behavior affects approximately 90 million people in the United States, most especially those from low-income groups and other at-risk populations such as those with addiction. Poor oral health can result from lack of access to regular preventive dental appointments, lack of access to restorative care when dental diseases are treatable, and low oral health knowledge that leads to poor oral health self-care behaviors. In addition, patients' dental anxiety can impede care, because highly anxious people often avoid dental appointments. To address these issues, this inquiry examined oral …

Study Of International Students' Definations Of, And Perceptions About, Domestic Violence Against Women, Sarbinaz Zamirovna Bekmuratova

All Graduate Theses, Dissertations, and Other Capstone Projects

The purpose of this study was to identify and compare definitions of, and perceptions about, domestic violence of international students enrolled in spring semester, 2012 at Minnesota State University, Mankato. These definitions and perceptions were compared according to the presence of domestic violence policies in the international students’ countries of origin as well as their gender and the length of residence in the United States. A quantitative cross-sectional online survey was conducted to collect data regarding participants’ definitions of different types of domestic violence, appropriateness of hitting and yelling in the relationship, and their perceptions about domestic violence. International students …

Providers' And Key Opinion Leaders' Attitudes, Beliefs, And Practices Regarding Emergency Contraception In India: Final Survey Report, M.E. Khan, Deepthi S. Varma, Isha Bhatnagar, Anvita Dixit, Martha Brady

Reproductive Health

The Population Council undertook this study to assess the knowledge, attitudes, and practices regarding emergency contraception (ECPs) among providers in public and private facilities and pharmacies in India. This study’s objectives were: 1) to assess providers’ knowledge of ECP’s biological mechanism; 2) to understand providers’ knowledge and attitudes about ECP’s safety, effectiveness, and availability as an over-the-counter drug; and 3) to identify providers’ definitions of “repeated use” and profiling of women who are “repeated users” of ECP. The study recommends intervention programs and advocacy strategies to increase knowledge and access to ECP.

The Reproductive Health Of Young People In Egypt, Nahla G. Abdel-Tawab, Noha Roushdy, Maia Sieverding

Poverty, Gender, and Youth

This Population Council brief presents results from the Survey of Young People in Egypt (SYPE) on reproductive health (RH). The SYPE results underscore the need for: the assessment of state and civil society initiatives to transmit RH information; a national, comprehensive, age-appropriate reproductive health module to be integrated into the educational program; a national campaign on HIV/AIDS and other sexually transmitted infections that targets young people of reproductive age; the integration of female circumcision into a broader approach to youth reproductive health and bodily rights; specialized reproductive health services for married adolescent girls; and further research on sexuality and reproductive …

The Health Of Vulnerable Adolescent Girls: A Strategic Investment For Double Return, Jennifer Catino

Poverty, Gender, and Youth

Worldwide there are 1.2 billion adolescents between the ages of 10 and 19. Nearly 90 percent of them live in developing countries, and approximately 600 million are female. While adolescence is normally a time of good health, numerous developmental and social changes occur during this period, many of which have health implications, especially for girls. Most of the girls and young women in the developing world live in conditions that make them vulnerable to health and social risks. They are often poor, out-of-school, married, migrants, members of ethnic minorities, or engaged in unsafe labor. Girls from many of the poorest …

Filles Eveillées ('Girls Awakened'): A Pilot Program For Migrant Adolescent Girls In Domestic Service In Urban Burkina Faso, Sarah Engebretsen, Gisele Kaboré, Leah Jarvis

Poverty, Gender, and Youth

Young people in Burkina Faso, especially adolescent girls, have few economic opportunities, particularly in rural areas. This drives migration to urban areas in search of employment. In 2010, the Population council conducted formative research on migrant adolescent girls in domestic service in urban Burkina Faso. Findings revealed that girls typically live with their employers and spend long days performing arduous work, leaving little time for schooling, building social networks, and developing skills necessary for adulthood. Most programs designed for this population intervene after something has gone wrong rather than building girls’ protective assets. In response to these findings, the Population …

Baseline And Endline Findings Of Filles Eveillées ('Girls Awakened'): A Pilot Program For Migrant Adolescent Girls In Domestic Service. Cohort 1 (2011–2012), Bobo-Dioulasso, Sarah Engebretsen

Poverty, Gender, and Youth

Burkina Faso has the tenth youngest population in the world, with 45 percent of the population below the age of 15. Young people in Burkina Faso, especially adolescent girls, have few economic opportunities, particularly in rural areas. This drives migration to urban areas in search of employment. On their own, girls are physically and economically vulnerable and many are at heightened risk for gender-based violence. The Population Council conducted formative research in 2010 to better understand the situation of migrant adolescent girls in domestic service in urban Burkina Faso, and subsequently designed a safe spaces intervention. The Filles Éveillées (“Girls …

Recours Aux Données Pour Révéler Et Sélectionner Les Adolescentes Les Plus Vulnérables, Sarah Engebretsen

Poverty, Gender, and Youth

Il est crucial d’investir dans les adolescentes du monde en développement, où une proportion déjà importante et grandissante de la population tombe dans la catégorie des moins de 24 ans. Il est essentiel pour protéger les droits à la scolarité, à l'intégrité corporelle et au mariage légal et choisi, et pour réduire la fertilité tout en augmentant la capacité de production. Il est essentiel de rendre les filles visibles si l’on veut que l’investissement soit ciblé sur les groupes qui présentent le plus grand risque de bilans non favorables. Tel est le principe de ce compte rendu: son but est …

Observations Initiales Et Finales De Filles Eveillées : Programme Pilote De Renforcement Des Compétences Des Adolescentes Migrantes Employées De Maison. Cohorte 1 (2011–2012), Bobo-Dioulasso, Sarah Engebretsen

Poverty, Gender, and Youth

Le Burkina Faso abrite la dixième population la plus jeune du monde, avec 45% de la population de moins de 15 ans. Les jeunes au Burkina Faso, en particulier les adolescentes, ont peu d'opportunités économiques, en particulier dans les zones rurales. Cela alimente la migration vers les milieux urbaines à la recherche de travail. Seules, les filles sont physiquement et économiquement vulnérables et beaucoup courent un risque élevé de violence sexiste. Le Population Council a mené une recherche formative en 2010 dans le but de mieux comprendre la situation des adolescentes migrantes employées de maison au Burkina Faso urbain, et …

Évaluation De Processus : Programme Filles Eveillées Pour Adolescentes Migrantes Employées De Maison Au Burkina Faso Urbain 2012, Leah Jarvis, Gisele Kaboré

Poverty, Gender, and Youth

Le programme «Filles Éveillées» a été conçu pour apporter aux adolescentes migrantes employées de maison les compétences, les connaissances et le capital social qui leur permettent de réduire leurs vulnérabilités et de s’ouvrir de nouveaux débouchés. Les observations tirées de la collecte de données quantitatives et qualitatives ont révélé le succès considérable du programme: il est largement apprécié et a été bien reçu par les participantes, les mentors, les membres de la communauté et tous les autres intéressés. En sa qualité de programme pilote, les obstacles à une mise en œuvre sans incidents auraient été inévitables, mais par leur détermination …

Does Cerclage Improve Neonatal Outcomes In A Molar Pregnancy And A Coexistent Fetus? A Case Report, Eduardo Aguin, Victor Aguin, Ligia Cisneros, Tina Aguin, Cosmas Van De Ven, Ray Bahado-Singh

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Complete hydatiform mole and coexistent viable fetus is very rare. The use of a cervical cerclage for cervical indications in the presence of this condition has never been reported. Although the diagnosis was made postnatal, the objective is to present a case with good neonatal outcome.

Case presentation

A patient presented with vaginal spotting around 23 weeks. She has a history of four preterm deliveries. Her cervix was dilated and a cerclage was placed. She presented again with PPROM around 25 weeks. She went into spontaneous preterm labor and delivered a viable fetus that is a healthy girl …

Healthcare Access And Mammography Screening In Michigan: A Multilevel Cross-Sectional Study, Tomi F. Akinyemiju, Amr S. Soliman, May Yassine, Mousumi Banerjee, Kendra Schwartz, Sofia Merajver

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Breast cancer screening rates have increased over time in the United States. However actual screening rates appear to be lower among black women compared with white women.

Purpose

To assess determinants of breast cancer screening among women in Michigan USA, focusing on individual and neighborhood socio-economic status and healthcare access.

Methods

Data from 1163 women ages 50-74 years who participated in the 2008 Michigan Special Cancer Behavioral Risk Factor Survey were analyzed. County-level SES and healthcare access were obtained from the Area Resource File. Multilevel logistic regression models were fit using SAS Proc Glimmix to account for clustering …

Filles Eveillées : Programme Pilote Pour Adolescentes Migrantes Employées De Maison Au Burkina Faso Urbain, Sarah Engebretsen, Gisele Kaboré, Leah Jarvis

Poverty, Gender, and Youth

Les jeunes Burkinabè n’ont guère de débouchés économiques, en particulier dans les milieux ruraux. En 2010, le Population Council a mené une recherche formative dans le but de mieux comprendre la situation des adolescentes migrantes employées de maison au Burkina Faso urbain. L’étude révèle qu’arrivées à la ville, ces filles vivent généralement chez leurs employeurs et travaillent de longues journées laborieuses. Il leur reste très peu de temps pour aller à l’école, développer des réseaux sociaux et acquérir les compétences nécessaires à la vie adulte. Il s’avère du reste que les programmes destinés à cette population interviennent en majorité après …

Injectable Contraceptives: Perspectives And Experiences Of Women And Health Care Providers In India, Shireen J. Jejeebhoy, A.J. Francis Zavier

Poverty, Gender, and Youth

This report is the result of a study that aimed to shed light on the feasibility and acceptability of making injectable contraceptives more widely available to women in India. The study focused on injectable contraceptive users, new method adopters, and healthcare providers drawn from the facilities of a range of reproductive health. Healthcare providers were, for the most part, in favor of offering injectable contraceptives, however, they argued strongly for certain prerequisites, such as comprehensive and sensitive counseling and effective follow-up. Findings further suggest that there is a demand for injectable contraceptives among women, and that both women and healthcare …