Public Health Commons^™

Vol 2 November '21 Cover, Publishing And Table Of Contents, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

A Seat At The Table: Interprofessional Education And Public Health, Kari Brisolara

Journal of the Louisiana Public Health Association

No abstract provided.

Students: Publish In The Jlpha, Edward Trapido

Journal of the Louisiana Public Health Association

No abstract provided.

Student Commentary: Exploring The Role Of White Supremacy In The Pursuit Of Health Equity, Kori Lannaman, Amber Brown

Journal of the Louisiana Public Health Association

No abstract provided.

Vol 2 November '21 Full Issue, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

Program Evaluation - The "Consider Breastfeeding" Mixed Media Campaign For Breastfeeding Promotion" An Evaluation Of A Pilot Study, Caitrin Alb, Melissa Goldin Evans, Meshawn Tarver, Renata A. Granger, Elizabeth Langlois, Katherine Theall

Journal of the Louisiana Public Health Association

No abstract provided.

Criminal Conviction History And Psychiatric Symptom Severity In An Outpatient Trauma Clinic, Kayling J. Beiter, Elizabeth Whitham, Adina Suss, Erika Rajo, Erich J. Conrad

Journal of the Louisiana Public Health Association

Background: Physically traumatic injuries (PTIs) occur frequently among individuals with past criminal convictions, and PTIs often result in posttraumatic stress disorder (PTSD) and depression; non-treatment increases risk of crime and PTI recidivism. The objective of this study was to assess rates of PTSD and depression symptom severity before and after 6 sessions of engagement with an evidence-based outpatient trauma recovery program among cohorts with and without conviction history. Methods: Individuals who were treated for a PTI at a Level 1 Trauma Center were offered connection to the hospital’s associated outpatient trauma recovery program targeting PTSD, depression, and other mental health …

Community-Informed Perspectives On Barriers To Accessing New Orleans' Community-Based Clinics, Nikki Khorsandi

Journal of the Louisiana Public Health Association

Background: Low income, under- and uninsured patients in New Orleans can access health services through community-based clinics. Ensuring access to these services is critical in reducing health disparities and requires community members’ perspectives on existing barriers and how they can be removed. Methods: An eight-member community advisory council (CAC) met monthly to share perceived barriers to accessing care and generate solutions for individual clinics, the system of clinics, or statewide policy. Results: Eighteen barriers were identified by councilmembers, five of which were specifically discussed throughout CAC tenure. Councilmembers identified that a root cause of these barriers stemmed from a lack …

Incarceration Of A Household Member During Childhood And Health-Related Quality Of Life, Amy Hilliker, Andrei Stefanescu

Journal of the Louisiana Public Health Association

No abstract provided.

The Impacts Of Police Raids On Female Strippers In New Orleans, Alexandra Jaoiche, Allie Beth, Jeni Stolow, Gretchen Clum

Journal of the Louisiana Public Health Association

No abstract provided.

Implicit Bias And Racial Disparities In School Discipline Responses In Louisiana, Casey L. Thomas, Kaylin Beiter, Ashley Fenton, Stephen Phillippi

Journal of the Louisiana Public Health Association

Background: In Louisiana schools, there is high incidence and racially disparate use of suspension and expulsion. This analysis assessed parish-level associations between racial disparities in school discipline and implicit racial biases. Methods: Investigators examined disparities in the proportion of Black students experiencing a school discipline outcome relative to White peers from all parishes (N=64) over four years. Implicit bias measures were derived from scores on the Implicit Association Test (IAT), which estimates a participant’s implicit associations between race categories and positive or negative feelings. IAT test date was used to stratify results by school year. The analysis included 10,652 IAT …

Development, Evaluation, And Enhancement Of A Transdisciplinary Project-Based And Community-Engaged Environmental Public Health Curriculum For Primary And Secondary Students, Victoria Peluso, Kari Brisolara, Haley Capello, Matthew Spence, Aubrey Gilliland, Adrienne Katner

Journal of the Louisiana Public Health Association

Background: The aim of this research was to develop, evaluate, and enhance a transdisciplinary projectbased curriculum in which students engage in citizen-science to introduce them to the field of environmental public health, a subject not traditionally taught outside of tertiary education. The curriculum was designed to involve students in the transdisciplinary collaborations needed for solving real world systems-dependent environmental public health problems. Methods: A curriculum was developed by graduate students which illustrates hazard identification; exposure assessment; and risk assessment, communication, intervention and evaluation through a community-engaged and project-based lens. The curriculum was taught successively over the span of two years …

A Phase Ib Dose Escalation Trial Of Ro4929097 (A Γ-Secretase Inhibitor) In Combination With Exemestane In Patients With Er + Metastatic Breast Cancer (Mbc), Julie A. Means-Powell, Ingrid A. Mayer, Roohi Ismail-Khan, Luis Del Valle, Debra Tonetti, Vandana G. Abramson, Melinda S. Sanders, Richard M. Lush, Claudia Sorrentino, Samarpan Majumder, Lucio Miele

School of Medicine Faculty Publications

Preclinical studies: have demonstrated a complex cross-talk between Notch and estrogen signaling in ERα-positive breast cancer. Gamma-secretase inhibitors (GSIs) are investigational agents that block the cleavage and activation of Notch receptors. In animal models of endocrine-resistant breast cancer, combinations of tamoxifen and GSIs produce additive or synergistic efficacy, while decreasing the intestinal toxicity of GSIs. However, results of a clinical trial of a GSI-endocrine therapy combination in the metastatic setting have not been published to date, nor had the safety of such combinations been investigated with longer term treatment. We conducted a phase 1b dose escalation trial (NCT01149356) of GSI …

Louisiana Medicaid Access For Treatment And Care For Hepatitis C Virus (La-Match) Project: A Cross-Sectional Study Protocol, Hasheemah Afaneh, Susanne Straif-Bourgeois, Evrim Oral, Ashley Wennerstrom, Olivia Sugarman, William T. Robinson, Angel Whittington, Edward Trapido

School of Public Health Faculty Publications

Introduction This article presents the Louisiana Hepatitis C Elimination Program’s evaluation protocol underway at the Louisiana State University Health Sciences Center–New Orleans. With the availability of direct-acting antiviral (DAA) agents, the elimination of Hepatitis C (HCV) has become a possibility. The HCV Elimination Program was initiated by the Louisiana Department of Health (LDH) Office of Public Health (OPH), LDH Bureau of Health Services Financing (Medicaid), and the Louisiana Department of Public Safety and Corrections (DPSC) to provide HCV treatment through an innovative pricing arrangement with Asegua Therapeutics, whereby a fixed cost is set for a supply of treatment over five …

Characteristics And Quality Of Mobile Apps Containing Prenatal Genetic Testing Information: Systematic App Store Search And Assessment, Ko Lin Wu, Rebeca Alegria, Jazzlyn Gonzalez, Harrison Hu, Haocen Wang, Robin Page, Patricia Robbins-Furman, Ping Ma, Tung-Sung Tseng, Lei Shih Chen

School of Public Health Faculty Publications

Background: Prenatal genetic testing is an essential part of routine prenatal care. Yet, obstetricians often lack the time to provide comprehensive prenatal genetic testing education to their patients. Pregnant women lack prenatal genetic testing knowledge, which may hinder informed decision-making during their pregnancies. Due to the rapid growth of technology, mobile apps are a potentially valuable educational tool through which pregnant women can learn about prenatal genetic testing and improve the quality of their communication with obstetricians. The characteristics, quality, and number of available apps containing prenatal genetic testing information are, however, unknown. Objective: This study aims to conduct a …

Changes Of Exercise, Screen Time, Fast Food Consumption, Alcohol, And Cigarette Smoking During The Covid-19 Pandemic Among Adults In The United States, Liwei Chen, Jian Li, Tong Xia, Timothy A. Matthews, Tung-Sung Tseng, Lu Shi, Donglan Zhang, Zhuo Chen, Xuesong Han, Yan Li, Hongmei Li, Ming Wen, Dejun Su

School of Public Health Faculty Publications

Objective: To investigate the impact of the COVID-19 pandemic on multiple lifestyle changes among adults in the United States (USA). Methods: We conducted a survey, the Health, Ethnicity, and Pandemic (HEAP) Study, in October 2020 among USA adults. Participants were selected from the United States using 48 sampling strata, including age, race, ethnicity, education, and gender, and were asked to report five lifestyle behaviors (i.e., exercise time, screen time, fast-food meal consumption, alcohol drinking, and cigarette smoking) before and during the COVID-19 pandemic. The associations of sociodemographic factors with each lifestyle change were estimated using weighted multivariable logistic regression models. …

Snpxe: Snp-Environment Interaction Pattern Identifier, Hui Yi Lin, Po Yu Huang, Tung-Sung Tseng, Jong Y. Park

School of Public Health Faculty Publications

Background: Interactions of single nucleotide polymorphisms (SNPs) and environmental factors play an important role in understanding complex diseases' pathogenesis. A growing number of SNP-environment studies have been conducted in the past decade; however, the statistical methods for evaluating SNP-environment interactions are still underdeveloped. The conventional statistical approach with a full interaction model with an additive SNP mode tests one specific interaction type, so the full interaction model approach tends to lead to false-negative findings. To increase detection accuracy, developing a statistical tool to effectively detect various SNP-environment interaction patterns is necessary. Results: SNPxE, a SNP-environment interaction pattern identifier, tests multiple …

The Role Of Education On Cancer Amenable Mortality Among Non-Hispanic Blacks &Amp; Non-Hispanic Whites In The United States (1989–2018), Alberto Barcelo, Linda Duffett-Leger, Maria Pastor-Valero, Juliana Pereira, Fernando A.B. Colugnati, Edward Trapido

School of Public Health Faculty Publications

Background: Cancer mortality in the U.S. has fallen in recent decades; however, individuals with lower levels of education experienced a smaller decline than more highly educated individuals. This analysis aimed to measure the influence of education lower than a high school diploma, on cancer amenable mortality among Non-Hispanic Whites (NHW) and Non-Hispanic Blacks (NHB) in the U.S. from 1989 to 2018. Methods: We analyzed data from 8.2 million death certificates of men and women who died from cancer between 1989 and 2018. We examined 5-year and calendar period intervals, as well as annual percent changes (APC). APC was adjusted for …

Use Of Geographic Information System Technology To Evaluate Health Disparities In Smoking Cessation Class Accessibility For Patients In Louisiana Public Hospitals, Tung-Sung Tseng, Michael D. Celestin, Qingzhao Yu, Mirandy Li, Ting Luo, Sarah Moody-Thomas

School of Public Health Faculty Publications

Research has shown cigarette smoking is a major risk factors for many type of cancer or cancer prognosis. Tobacco related health disparities were addressed continually in cancer screening, diagnosis, treatment, prevention and control. The present study evaluated the health disparities in attendance of smoking cessation counseling classes for 4,826 patients scheduled to attend between 2005 and 2007. Of 3,781 (78.4%) patients with records to calculate the distance from their home domicile to counseling sites using Geographic Information System technology, 1,435 (38%) of smokers who attended counseling had shorter travel distances to counseling sites (11.6 miles, SD = 11.29) compared to …

Cancer In Louisiana: 2014-2018, Volume 36, Louisiana Tumor Registry, Lauren Maniscalco, Mei-Chin Hsieh, Christina Lefante, Yong Yi, Lisa Pareti, Brent Mumphrey, Mary Anne Lynch, Xiao-Cheng Wu, Quintrelé Jones, Tingting Li

Policy & Position Papers

Mission:

To collect and report complete, high-quality, and timely population-based cancer data in Louisiana to support cancer research, control, and prevention.

Vision:

To reduce suffering and death from cancer using information collected by the Louisiana Tumor Registry.

History:

Cancer registration in Louisiana began in 1947 at the Charity Hospital Tumor Registry in New Orleans. In 1974, as part of its Surveillance, Epidemiology and End Results (SEER) Program, the National Cancer Institute provided funds for a population-based cancer incidence and survival registry covering Jefferson, Orleans, and St. Bernard parishes. Five years later, the Louisiana Tumor Registry (LTR) was transferred to the …

Urban And Rural Disparities In A Wechat-Based Smoking Cessation Intervention Among Chinese Smokers, Ting Luo, Mirandy Li, Donna Williams, Jackson Fritz, Stephen W. Phillippi, Qingzhao Yu, Stephen Kantrow, Liwei Chen, Yongchun Chen, Kaylin Beiter, Tung-Sung Tseng

School of Public Health Faculty Publications

Introduction: Tobacco use, which is directly responsible for 10% of total deaths per year globally, remains consistently high, with approximately 20% of the population reporting regular consumption globally. Moreover, health disparities regarding tobacco consumption and smoking cessation are growing between rural and urban populations worldwide. Social media interventions for tobacco cessation may effectively reach both groups. The objective of this study was to evaluate the efficacy of a WeChat-delivered smoking cessation intervention among rural and urban Chinese smokers, and to assess moderating variables that may contribute to differential intervention efficacy. Methods: WeChat was used to recruit smokers into this intervention …

Perceptions Of Autism Spectrum Disorder (Asd) Etiology Among Parents Of Children With Asd, Wei-Ju Chen, Zihan Zhang, Haocen Wang, Tung-Sung Tseng, Ping Ma, Lei-Shih Chen

School of Public Health Faculty Publications

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and restricted or repetitive behaviors. Parental perceptions of the etiology of their child’s ASD can affect provider–client relationships, bonding between parents and their children, and the prognosis, treatment, and management of children with ASD. Thus, this study sought to examine the perceptions of ASD etiology of parents of children with ASD. Methods: Forty-two parents of children diagnosed with ASD were recruited across Texas. Semi-structured interviews were conducted individually. All interviews were recorded and later transcribed verbatim for content analysis utilizing NVivo 12.0 (QSR International, Doncaster, Australia). …

Processes For Implementing Community Health Worker Workforce Development Initiatives, Colleen Barbero, Theresa Mason, Carl Rush, Meredith Sugarman, Aunima R. Bhuiya, Erika B. Fulmer, Jill Feldstein, Naomi Cottoms, Ashley Wennerstrom

School of Public Health Faculty Publications

Introduction: The objective of this observational, cross-sectional study was to identify, document, and assess the progress made to date in implementing various processes involved in statewide community health worker (CHW) workforce development initiatives. Methods: From September 2017 to December 2020, we developed and applied a conceptual model of processes involved in implementing statewide CHW initiatives. One or more outputs were identified for each model process and assessed across the 50 states, D.C., and Puerto Rico using peer-reviewed and gray literature available as of September 2020. Results: Twelve statewide CHW workforce development processes were identified, and 21 outputs were assessed. We …

Examining Behavioral Health Services For Louisiana Youth With January 2019 To June 2020 Medicaid Claims Data, Evidence To Practice, Cep Briefs, Sonita Singh, Brian Bumbarger, Kaylin Beiter, Lindsay Simpson, Stephen Phillippi

Policy & Position Papers

No abstract provided.

The Impact Of Human Trafficking Training On Healthcare Professionals' Knowledge And Attitudes, Hayoung Lee, Julia Geynisman-Tan, Sarah Hofer, Emily Anderson, Sahar Caravan, Kanani Titchen

School of Medicine Faculty Publications

Objectives: The objective of this study was to evaluate a CME-accredited human trafficking didactic and discussion-based training for healthcare professionals by comparing participant knowledge and attitudes on human trafficking before and after attending the training. Methods: A novel 18-item survey was developed to test the knowledge of and attitudes towards human trafficking. Participants of 17 standardized trainings delivered by 4 physician-trainers over a two-year period were invited to take a pre-test and 2 post-tests at 1-week and 6-months post training. Surveys were anonymously collected and linked to each participant with a de-identified number. Data were analyzed using SPSS software with …

Klk3 Snp–Snp Interactions For Prediction Of Prostate Cancer Aggressiveness, Hui Yi Lin, Po Yu Huang, Chia Ho Cheng, Heng Yuan Tung, Zhide Fang, Anders E. Berglund, Ann Chen, Jennifer French-Kwawu, Darian Harris, Julio Pow-Sang, Kosj Yamoah, John L. Cleveland, Shivanshu Awasthi, Robert J. Rounbehler, Travis Gerke, Jasreman Dhillon, Rosalind Eeles, Rosalind Eeles, Zsofia Kote-Jarai, Zsofia Kote-Jarai

School of Public Health Faculty Publications

Risk classification for prostate cancer (PCa) aggressiveness and underlying mechanisms remain inadequate. Interactions between single nucleotide polymorphisms (SNPs) may provide a solution to fill these gaps. To identify SNP–SNP interactions in the four pathways (the angiogenesis-, mitochondria-, miRNA-, and androgen metabolism-related pathways) associated with PCa aggressiveness, we tested 8587 SNPs for 20,729 cases from the PCa consortium. We identified 3 KLK3 SNPs, and 1083 (P < 3.5 × 10–9) and 3145 (P < 1 × 10–5) SNP–SNP interaction pairs significantly associated with PCa aggressiveness. These SNP pairs associated with PCa aggressiveness were more significant than each of their constituent SNP individual effects. The majority (98.6%) of the 3145 pairs involved KLK3. The 3 most common gene–gene interactions were KLK3-COL4A1:COL4A2, KLK3-CDH13, and KLK3-TGFBR3. Predictions from the SNP interaction-based polygenic risk score based on 24 SNP pairs are promising. The prevalence of PCa aggressiveness was 49.8%, 21.9%, and 7.0% for the PCa cases from our cohort with the top 1%, middle 50%, and bottom 1% risk profiles. Potential biological functions of the identified KLK3 SNP–SNP interactions were supported by gene expression and protein–protein interaction results. Our findings suggest KLK3 SNP interactions may play an important role in PCa aggressiveness.

Understanding The Patient Journey To Diagnosis Of Lung Cancer, Yichen Zhang, Michael J. Simoff, David Ost, Oliver J. Wagner, James Lavin, Beth Nauman, Mei Chin Hsieh, Xiao Cheng Wu, Brian Pettiford, Lizheng Shi

School of Public Health Faculty Publications

Objective: This research describes the clinical pathway and characteristics of two cohorts of patients. The first cohort consists of patients with a confirmed diagnosis of lung cancer while the second consists of patients with a solitary pulmonary nodule (SPN) and no evidence of lung cancer. Linked data from an electronic medical record and the Louisiana Tumor Registry were used in this investigation. Materials and methods: REACHnet is one of 9 clinical research networks (CRNs) in PCORnet®, the National Patient-Centered Clinical Research Network and includes electronic health records for over 8 million patients from multiple partner health systems. Data from Ochsner …

Deep Active Learning For Classifying Cancer Pathology Reports, Kevin De Angeli, Shang Gao, Mohammed Alawad, Hong Jun Yoon, Noah Schaefferkoetter, Xiao Cheng Wu, Eric B. Durbin, Jennifer Doherty, Antoinette Stroup, Linda Coyle, Lynne Penberthy, Georgia Tourassi

School of Public Health Faculty Publications

Background: Automated text classification has many important applications in the clinical setting; however, obtaining labelled data for training machine learning and deep learning models is often difficult and expensive. Active learning techniques may mitigate this challenge by reducing the amount of labelled data required to effectively train a model. In this study, we analyze the effectiveness of 11 active learning algorithms on classifying subsite and histology from cancer pathology reports using a Convolutional Neural Network as the text classification model. Results: We compare the performance of each active learning strategy using two differently sized datasets and two different classification tasks. …

Evidence Based Programs (Ebp) Rate Increase Cost Projection Model, Evidence To Practice, Cep Briefs, Ronnie Rubin, Kaylin Beiter, Stephen Phillippi

Policy & Position Papers

No abstract provided.

Financial & Policy Challenges To Evidence Based Practice (Ebp) Implementation, Evidence To Practice, Cep Briefs, Ronnie Rubin, Willandra Whiting, Stephen Phillippi

Policy & Position Papers

No abstract provided.