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2020

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Articles 61 - 80 of 80

Full-Text Articles in Other Medicine and Health Sciences

In Gratitude Of 2019 Jpcrr Peer Reviewers Jan 2020

In Gratitude Of 2019 Jpcrr Peer Reviewers

Journal of Patient-Centered Research and Reviews

Journal of Patient-Centered Research and Reviews gratefully acknowledges the contributions of its submission reviewers from the previous year. Peer review is an essential component to publishing high-quality scientific literature. The editors thank these individuals for their generous volunteerism.


Analyses Of The 2019 Nobel Prize In Physiology Or Medicine: Molecular Machinery For Cellular Oxygen Level Response, Neyda V. Gilman Jan 2020

Analyses Of The 2019 Nobel Prize In Physiology Or Medicine: Molecular Machinery For Cellular Oxygen Level Response, Neyda V. Gilman

Library Scholarship

Gregg L. Semenza, William G Kaelin, Jr, and Sir Peter J. Ratcliffe were awarded the 2019 Nobel Prize for Physiology or Medicine on October 7, 2019. Their work led to the understanding of how cells recognize and adapt to varying oxygen levels. Hypoxia-inducible nuclear factors play an essential role in this mechanism by turning on other genes that work towards increasing oxygen levels in hypoxic environments. Other vital pieces of the machinery include von Hippel-Lindau proteins and prolyl hydroxylation. Due to the necessity of oxygen in numerous human physiological systems, this discovery will likely have nearly immeasurable impacts on human …


Human Factor Associations With Safety Events In Radiation Therapy, Sheri M. Weintraub Jan 2020

Human Factor Associations With Safety Events In Radiation Therapy, Sheri M. Weintraub

Health Sciences Program Student Theses, Dissertations and Capstones

One important connection for all human beings is that we have a shared need for health care and are at some risk of experiencing medical error. Errors documented in the field of radiation therapy have included tragic levels of suffering and even death from preventable mistakes. Efforts to improve patient safety include an approach called incident learning that makes use of information about known errors to inform safetyimprovement strategy. The complexity of human contributing factors challenges those safety improvements. The problem addressed by this dissertation study is that radiation therapy puts patients at risk, and the incident learning systems designed …


The Relationship Between Youth Inactivity And Health, Alexis Michelle Dress-Moran Jan 2020

The Relationship Between Youth Inactivity And Health, Alexis Michelle Dress-Moran

2020 Symposium Posters

As technology advances, youth engage in the sedentary lifestyle of playing computer games, leaving no time for physical activities. The purpose of this study is to prove the relationship between youth inactivity and health. The inactive behavior of adolescents has contributed to increased health issues. Among them are cardiovascular diseases, obesity, depression, type 2 diabetes, and hypertension. The research data was collected in the form of secondary data from a literature review, where credible peer reviewed articles published between 2013 to 2020, and government websites were used for the study. By studying the connection of physical inactivity and the health …


Relationship Between Alpha-1 Antitrypsin Deficiency And Obstructive Sleep Apnea, Lindsay Megenhardt Jan 2020

Relationship Between Alpha-1 Antitrypsin Deficiency And Obstructive Sleep Apnea, Lindsay Megenhardt

Health Sciences Program Student Theses, Dissertations and Capstones

Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that causes inadequate production of the alpha-1 antitrypsin (AAT) protein, which is known to protect connective tissues in the body from destruction. The purpose of this dissertation study was to identify if individuals with mild to severe AATD are at higher risk for developing obstructive sleep apnea than the general population. The investigator hypothesized there would be a higher prevalence of OSA in the AATD population due to the etiology of disease. A seven-question sleep apnea risk assessment questionnaire, STOPBAG, was applied to the retrospective, de-identified, self-reported 2,338 participant responses from the …


Production Of Flavoured Fiti Probiotic Yoghurt For The London Community, Chengyu (Jennifer) Guo, Stephanie Huff, Maria Medina, Bob Gough, Sharareh Hekmat Jan 2020

Production Of Flavoured Fiti Probiotic Yoghurt For The London Community, Chengyu (Jennifer) Guo, Stephanie Huff, Maria Medina, Bob Gough, Sharareh Hekmat

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.


The Use Of An Embedded Librarian To Enhance Student Information Literacy Skills: A Pilot Study, Elaina J. Dalomba, Elizabeth Kavanaugh, Kaitlin Manbeck, Samantha O'Neill, Kyle Soldevilla, Melanie Watson, Ellen Mclaughlin Jan 2020

The Use Of An Embedded Librarian To Enhance Student Information Literacy Skills: A Pilot Study, Elaina J. Dalomba, Elizabeth Kavanaugh, Kaitlin Manbeck, Samantha O'Neill, Kyle Soldevilla, Melanie Watson, Ellen Mclaughlin

Journal of Occupational Therapy Education

This pilot study explored an embedded librarian (EL) intervention to enhance occupational therapy student information literacy skills development. The EL provided computer laboratory and in-class instruction, online presence in the classroom website, and extensive office hours to assist students in the identification of information needed, determination of how and where to find scholarly information needed, and assessment and utilization of information retrieved to meet assignment requirements. Participants were 46 third-year (junior) occupational therapy students. Three tools were used to assess skills pre and post intervention: the Student Assessment of Information Literacy Skills, the Student Perception of Literacy Skills-Q (SPIL-Q), and …


Internet Of Things For Sustainable Human Health, Abdul Salam Jan 2020

Internet Of Things For Sustainable Human Health, Abdul Salam

Faculty Publications

The sustainable health IoT has the strong potential to bring tremendous improvements in human health and well-being through sensing, and monitoring of health impacts across the whole spectrum of climate change. The sustainable health IoT enables development of a systems approach in the area of human health and ecosystem. It allows integration of broader health sub-areas in a bigger archetype for improving sustainability in health in the realm of social, economic, and environmental sectors. This integration provides a powerful health IoT framework for sustainable health and community goals in the wake of changing climate. In this chapter, a detailed description …


Heart Rate Variability And Cardiovascular Adaptations Among Cancer-Survivors Following A 26-Week Exercise Intervention, Heather P. Tarleton Jan 2020

Heart Rate Variability And Cardiovascular Adaptations Among Cancer-Survivors Following A 26-Week Exercise Intervention, Heather P. Tarleton

Health and Human Sciences Faculty Works

Cardiotoxicity as a result of cancer treatment contributes to autonomic dysfunction and decreased cardiorespiratory fitness among cancer survivors. These deleterious cardiovascular outcomes reduce the survival prognosis for cancer patients and contribute to poor quality of life among survivors. Exercise interventions have been shown as effective in mitigating treatment-related side effects. However, previously published interventions have not explored the potential for improvement in autonomic dysfunction (heart rate variability, HRV). This study examined cardiovascular adaptations in cancer survivors (n = 76) who participated in a 26-week intervention consisting of combined aerobic and resistance training (CART). The most noteworthy improvements occurred during the …


The Effects Of Gspt1 Degradation On Serum Calcium, Parathyroid Hormone, And Fibroblast Growth Factor 23 Concentrations In Human Cereblon Knock-In Mice, Kamran Ghoreishi Jan 2020

The Effects Of Gspt1 Degradation On Serum Calcium, Parathyroid Hormone, And Fibroblast Growth Factor 23 Concentrations In Human Cereblon Knock-In Mice, Kamran Ghoreishi

Theses and Dissertations

Test article CC-325 is a potent oral cereblon (CRBN) modulator that has shown potent G1 to S phase transition 1 (GSPT1) degradation and anti-tumor activity in pre-clinical models. One of the adverse effects associated with CC-325 was dose dependent hypocalcemia, which was determined to be an on-target toxicity.

To investigate the mechanism of hypocalcemia, we conducted a toxicity study in human cereblon (huCRBN) knock-in (KI) mice with CC-325. The huCRBN KI mice are transgenic mice engineered to express human cereblon that is capable of binding to CRBN and degrading GSPT1. Four groups of mice were treated with vehicle (0 mg/kg), …


Student Experiences With Engagement In A Nursing And Physical Therapy Interprofessional Education Simulation, Sarah Koplow, Melissa Morris, Shari Rone-Adams, Heather Hettrick, Bini Litwin, Lisa B. Soontupe, Archana Vatwani Jan 2020

Student Experiences With Engagement In A Nursing And Physical Therapy Interprofessional Education Simulation, Sarah Koplow, Melissa Morris, Shari Rone-Adams, Heather Hettrick, Bini Litwin, Lisa B. Soontupe, Archana Vatwani

Internet Journal of Allied Health Sciences and Practice

Purpose: Interprofessional Education (IPE) incorporated into healthcare discipline instruction has been shown to be successful in improving the understanding perceptions of complimentary professions. The purpose of this mixed method study was to measure differences in perceptions of early Baccalaureate of Science in Nursing (BSN) students and Doctor of Physical Therapy (DPT) with participation in a immersive interprofessional education experience. Method: Students completed a pre and posttest survey consisting of the Readiness for Interprofessional Learning Scale and several short answer qualitative questions. Cohorts of BSN and DPT students participated in a computerized mannequin simulation experience or a hybrid simulation. Results: Students …


Predicting Pance Outcomes From First Year Evaluative Measures In A Pbl Curriculum, Anthony Goreczny, Susan Hawkins, John R. Laird Jan 2020

Predicting Pance Outcomes From First Year Evaluative Measures In A Pbl Curriculum, Anthony Goreczny, Susan Hawkins, John R. Laird

Internet Journal of Allied Health Sciences and Practice

Purpose: Previous research has explored various Physician Assistant (PA) student evaluative measures to see if they have predictive validity with regard to Physician Assistant National Certifying Exam (PANCE) scores. Recent literature has begun to evaluate how measures from the first year of didactic education might be helpful in identifying at-risk individuals early in the program. The purpose of this paper was to extend work in that area within a problem-based learning (PBL) curriculum. Method: Participants included 140 students from two consecutive PA classes. Data were imported regarding each student’s evaluative measures of multiple choice question (MCQ) examinations, patient management assessments …


Opioids And An Active Population: Athletic Trainers' Perceptions, Dana Karlene Bates Jan 2020

Opioids And An Active Population: Athletic Trainers' Perceptions, Dana Karlene Bates

Internet Journal of Allied Health Sciences and Practice

Purpose: Opioid use, misuse, and abuse are occurring in both high school and collegiate athletes. There is limited research that examines athletic trainers' perceptions of opioids. The purpose of this qualitative research study was to investigate athletic trainers’ awareness and practice of opioids in an active population. Method: Qualitative inquiry was used to explore athletic trainers' awareness of opioids in an active population. Ten athletic trainers (7 male, 3 female) employed in the Northwest Athletic Training Association (6 collegiate, 4 high schools) volunteered for this study. Phone interviews were conducted in July to September 2017 with a semi-structured …


An Interprofessional Clinical Placement In A Primary Healthcare Setting: A Pilot Study, Christina Aggar, Beth Mozolic-Staunton, Renee Joyce Lovi, Maggie Scorey, Melissa Kemp, Tara Walker, Sian Lewis Jan 2020

An Interprofessional Clinical Placement In A Primary Healthcare Setting: A Pilot Study, Christina Aggar, Beth Mozolic-Staunton, Renee Joyce Lovi, Maggie Scorey, Melissa Kemp, Tara Walker, Sian Lewis

Internet Journal of Allied Health Sciences and Practice

Purpose: Internationally, and in Australia, interprofessional education (IPE) is becoming typical in primary healthcare delivery and is core to delivering patient-centred care. It is essential that primary healthcare education develop interprofessional capacity in order to produce a skilled workforce. An IPE clinical placement for undergraduate health students was developed and piloted in primary healthcare settings. The aim of this study was to evaluate the impact of the IPE clinical placement in a primary healthcare setting on students’ perceptions of interprofessional education. Method: A pre-post placement validated questionnaire (n=19) indicated overall perceptions of IPE significantly increased over the course of …


The Positive Impact Of Occupational Therapy Involvement In Interprofessional Education, Wendie Leveille, James Brandes, Karene Boos, Amy Vega, Barbra Beck, Barbara Ruggeri, Thomas E. St. George, Jane Hopp Jan 2020

The Positive Impact Of Occupational Therapy Involvement In Interprofessional Education, Wendie Leveille, James Brandes, Karene Boos, Amy Vega, Barbra Beck, Barbara Ruggeri, Thomas E. St. George, Jane Hopp

Journal of Occupational Therapy Education

It is essential that members of a successful interprofessional healthcare delivery team understand the crucial roles and responsibilities of each profession. Participation in interprofessional education and practice has been suggested to improve understanding of the roles of each discipline on an allied health team, however, often understanding of the occupational therapy scope of practice is confusing to other allied health professionals. This study presents the outcomes of a community-based interprofessional practice experience with occupational therapy, physical therapy, and physician assistant students on perceived understanding of each profession’s roles and responsibilities. In addition, this study introduces the Primary Care Training and …


Job Stress Effects On Job Satisfaction And Attrition In 9-1-1 Call Centers, Damarys Jaile Gilligan Jan 2020

Job Stress Effects On Job Satisfaction And Attrition In 9-1-1 Call Centers, Damarys Jaile Gilligan

Theses and Dissertations

In 9-1-1 call centers across the nation the personnel shortage has become a crisis. The nature of the job of a 9-1-1 telecommunicator is stressful due to the high volume of emergency calls. This applied dissertation was designed to learn if there is a relationship between job stress, burnout levels, and job satisfaction in 9-1-1 telecommunicators. This was a nonexperimental quantitative survey research with a correlational approach. The population was a nonprobability convenience sample recruited through the Survey Monkey Audience platform. Data was collected at one point in time. A total of 37 participants took part in the study. All …


Modulation Of Medical Condition Likelihood By Patient History Similarity, Jonathan Turner, Dympna O'Sullivan, Jon Bird Jan 2020

Modulation Of Medical Condition Likelihood By Patient History Similarity, Jonathan Turner, Dympna O'Sullivan, Jon Bird

Articles

Introduction: We describe an analysis that modulates the simple population prevalence derived likelihood of a particular condition occurring in an individual by matching the individual with other individuals with similar clinical histories and determining the prevalence of the condition within the matched group.

Methods: We have taken clinical event codes and dates from anonymised longitudinal primary care records for 25,979 patients with 749,053 recorded clinical events. Using a nearest neighbour approach, for each patient, the likelihood of a condition occurring was adjusted from the population prevalence to the prevalence of the condition within those patients with the closest …


Feasibility Of A Readiness Exam For Predicting Radiography Program Success: A Pilot Study, Tammy L. Webster, Sarah B. Mcbrien, Gregory M. Mehrer, Harlan R. Sayles Jan 2020

Feasibility Of A Readiness Exam For Predicting Radiography Program Success: A Pilot Study, Tammy L. Webster, Sarah B. Mcbrien, Gregory M. Mehrer, Harlan R. Sayles

Internet Journal of Allied Health Sciences and Practice

ABSTRACT

Background: Research investigating predictors of academic success in rigorous health science education is valuable for curricular intervention for identified at-risk students. Various predictors of success have been investigated, but the literature is insufficient when examining anatomy and physiology readiness scores as they correlate to radiography curricular success. This pilot study assessed the correlation between readiness exam scores and programmatic course GPA to determine if the scores could be used as a metric for identifying academic success resources for incoming students. Cohorts of the radiography program at a midwestern health sciences center demonstrated a longitudinal trend of difficulty with anatomy …


Comparing The Perceptions Of Interprofessional Socialization Among Health Profession Students, Karen Aul, Jody Long Jan 2020

Comparing The Perceptions Of Interprofessional Socialization Among Health Profession Students, Karen Aul, Jody Long

Internet Journal of Allied Health Sciences and Practice

Introduction: Based on a review of literature, there is a gap of knowledge on how students perceive the professional roles and responsibilities of other disciplines. The purpose of this study was to explore the perceptions of interprofessional socialization among health profession students. Subjects: Participants included 300 undergraduate and 114 graduate students from eight health disciplines: nursing, communication disorders, physical therapy, social work, radiological science, occupational therapy, clinical lab science, and nutritional science. Methods: Data were collected using the Interprofessional Socialization and Valuing Scale (ISVS-21). The participants rated 21 items about their beliefs, behaviors, and attitudes of interprofessional socialization on a …


Ethics Committees For Clinical Experimentation At International Level With A Focus On Italy, Zakira Naureen, Tommaso Beccari, Robert S. Marks, Richard Brown, Lorenzo Lorusso, Derek Pheby, Stanislav Miertus, Karen L. Herbst, Liborio Stuppia, Gary T. Henehan, Benedetto Falsini, Ludovica Lumer, Munis Dundar, Matteo Bertelli, International Bioethical Study Group Jan 2020

Ethics Committees For Clinical Experimentation At International Level With A Focus On Italy, Zakira Naureen, Tommaso Beccari, Robert S. Marks, Richard Brown, Lorenzo Lorusso, Derek Pheby, Stanislav Miertus, Karen L. Herbst, Liborio Stuppia, Gary T. Henehan, Benedetto Falsini, Ludovica Lumer, Munis Dundar, Matteo Bertelli, International Bioethical Study Group

Articles

Guiding legislation and associated bureaucracy for the ethical review of clinical trials observational studies and food related research play an important role in the competitiveness of a nation in the face of tough global competition to attract sponsors and investigators. This is of particular relevance in the case of multicentre trials and multidisciplinary research. Accordingly, in this report we tried to gather in-depth knowledge of the current role and practices of ethics committees nationwide in both clinical and research settings. This mini-review aims to describe the formulation and organization of ethical committees in Italy in order to provide a focus …