Other Medicine and Health Sciences Commons^™

Financial Conflicts Of Interest Change After A High-Impact Clinical Trial Publication In Oncology, Craig L. Cambridge, Emily Stern Gatof, Glen J. Weiss, Roger B. Davis

Journal of Patient-Centered Research and Reviews

Purpose: Because financial conflicts of interest (FCOIs) may potentially influence patient care, hospital drug formularies, and treatment guidelines, it is important that these are disclosed. The purpose of this observational study was to quantify the changes in FCOI among U.S.-based academic authors in industry-sponsored oncology trials after a high-impact publication.

Methods: A list of all U.S.-based academic authors (authors) of industry-sponsored solid tumor clinical trials published between August 1, 2014, and December 31, 2015, in 6 high-impact journals (New England Journal of Medicine, Nature, Science, Lancet Oncology, Journal of Clinical Oncology, and Cancer Discovery) was assembled. Studies were limited to …

Alumni Journal - Volume 91, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
8 | School of Medicine News
10 | Alumni News
11 | AIMS Report
12 | Students

Graduation 2020
13 | Graduation Feature: A letter to the graduates, awards, photos, residency information, and more
14 | The Missing Regalia: Debra L. Stottlemyer '86 shares how alumni supported the senior class

Features
30 | Gloves: Hannah C. Lokos '20 tells a story of how she saw a glimpse of God
32 | Department Reports: Emergency Medicine and Urology: E. Lea Walters '94 and Herbert …

Trends In Cancer Prevalence In Punjab, Pakistan: A Systematic Study From 2010 To 2016, Sana Hafeez, Asmat Mahmood, Rizwan Ullah Khan, Naila Malkani

Journal of Bioresource Management

Cancer is the second leading cause of death globally. However, in Pakistan, in the absence of a national cancer registry, it is difficult to predict the current status of cancer incidence. Therefore, a need was felt to design a study that can give a depiction of the prevalence of common cancer types and their relevance to the local population in the absence of a proper cancer registry system. In view of this, data was collected from 2010 to 2016 for breast, prostate, head and neck, cervical and colorectal cancer from the cancer hospitals and centres located all over Punjab, Pakistan. …

Quantifying Differences In Pill Swallow Patterns In Adults, Catherine A. Sullivan, Luis F. Riquelme

Annual SHSP Student Research and Scholarship Day

Difficulty swallowing pills has become an increasing complaint among patients visiting swallow evaluation centers across the globe. Deficits are reported in healthy individuals as well as in clinical populations. In the USA, 40% of 679 persons responding to a survey reported difficulty swallowing pills (Business Wire, 2009). In an effort to facilitate pill intake, several modifications have been reported: use of liquid formulations, crushing tablet, opening capsule, whole pill mixed with food or via feeding tube (Cornish, 2005). A survey of 40 nurses revealed the most common modification was to use apple sauce (Riquelme et al., 2009). Current literature on …

Safe And Effective Disinfection Of Show Cave Infrastructure In A Time Of Covid-19, Hazel A. Barton

International Journal of Speleology

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has been responsible for over 650,000 deaths worldwide. Transmission of SARS-CoV-2 occurs primarily through airborne transmission or direct human contact, demonstrating the importance of social distancing measures and the use of face masks to prevent infection. Nonetheless, the persistence of coronavirus on surfaces means that disinfection is important to limit the possibility of contact transmission. In this paper, the potential for various surfaces in show caves to serve as sources for SARS-CoV-2 infection is examined. Given the isoelectric potential (pI) of SARS and SARS-like coronaviruses, it is likely that they are …

Strategies To Address Substance-Abusing And Substance-Impaired Healthcare Professionals, Anna Marie Smith, Douglas G. Campbell

International Journal of Applied Management and Technology

This research explored strategies used by some healthcare leaders to address substance abusing and impaired healthcare professionals. The conceptual framework for this qualitative case study was the concept of due diligence. Data were collected from 40 managers and supervisors, 3 executives, and company documents, and analyzed to reveal elements of a comprehensive strategy. A effective comprehensive strategy consists of policies that address the causes, the short term and long term aspects, and both the ethical and legal aspects. Policies and procedures are equally applied, are easily accessible, are well communicated, are supported by training, provides positive encouragement. provides a path …

Commencement Program 2020 (School Of Medicine), Loma Linda University

Commencement Programs

CONTENTS

2 | Message from the President

3 | Message from the Dean

4 | University History Highlights

6 | Candidates for Degrees

Costs Of Maternity Leave To Support Breastfeeding; Brazil, Ghana And Mexico, Mireya Vilar-Compte, Graciela M. Teruel, Diana Flores-Peregrina, Grace J. Carroll, Gabriela S. Buccini, Rafael Perez-Escamilla

Department of Public Health Scholarship and Creative Works

Objective To develop a method to assess the cost of extending the duration of maternity leave for formally-employed women at the national level and apply it in Brazil, Ghana and Mexico. Methods We adapted a World Bank costing method into a five-step method to estimate the costs of extending the length of maternity leave mandates. Our method used the unit cost of maternity leave based on working women’s weekly wages; the number of additional weeks of maternity leave to be analysed for a given year; and the weighted population of women of reproductive and legal working age in a given …

Commencement Program 2020 (School Of Allied Health Professions), Loma Linda University

Commencement Programs

CONTENTS

2 | Message from the President

3 | Message from the Dean

4 | University History Highlights

6 | Candidates for Degrees

Reducing The Rate Of Falls In Hospice Patients: A Fall Prevention Pilot Program, Allison Floyd

Doctor of Nursing Practice Final Manuscripts

Background and Evidence Problem: As the population ages, there is an increase in the incidents of falls. Falls are the predominant cause of both nonfatal and fatal injuries among adults aged 65 years and older (Bergen et al., 2016). Extensive research has been conducted in fall prevention in hospitals, skilled nursing, and rehabilitation units. End-of-life care in a hospice setting presents a greater challenge in risk identification and prevention of falls. A local hospice had 457 falls between July 2018 to mid-March 2019 with a lack of consistent, detailed, fall education and documentation.

Evidence-Based Practice Intervention: Utilizing the American Geriatrics …

Orthostatic Blood Pressure And Arterial Stiffness In Persons With Spinal Cord Injury: The Effect Of The Renin Angiotensin Aldosterone System, Caitlyn G. Katzelnick

Seton Hall University Dissertations and Theses (ETDs)

With advances in acute medical care, longevity has increased in persons with SCI; however, morbidity due to cardiovascular disease (CVD) occurs at an earlier age compared to the general population. Arterial stiffness (AS) is recognized as an independent risk factor for CVD and, specifically, pulse wave velocity (PWV) has been proven to be a valid tool to predict and track structural arterial changes that reflect arteriosclerosis. Evidence has shown that persons with SCI have increased AS compared to uninjured able-bodied controls; however, possible contributors to this increase are not yet fully understood. After a SCI, sympathetic control in the regions …

Screening And Characterization Of A Pan-Gtpase Inhibitor, Leyla Akhadov

Biomedical Engineering ETDs

Abnormal functioning of small GTPases is implicated in a variety of diseases, ranging from neurological and developmental diseases to cancer. In fact, mutant GTPases are found in up to 30% of cancers. Thus, small GTPases are a highly relevant target in drug discovery and development. High-throughput targeted screening of small molecules is the most productive method of discovering compounds that can give insights into drug development. This thesis describes improvements made to a high-throughput GTPase-targeted screening method to minimize confounding systematic error. It also describes the follow-up characterization of a compound that was identified in a high-throughput screen. The compound …

Implementation Of A Computer-Vision System As A Supportive Diagnostic Tool For Parkinson’S Disease, Diego Machado Reyes

Honors Theses

Parkinson’s disease is the second most common neurodegenerative disorder, affecting nearly 1 million people in the US and it is predicted that the number will keep increasing. Parkinson’s disease is difficult to diagnose due to its similarity with other diseases that share the parkinsonian symptoms and the subjectivity of its assessment, thus increasing the probabilities of misdiagnosis. Therefore, it is relevant to develop diagnostic tools that are quantitatively based and monitoring tools to improve the patient’s quality of life. Computer-based assessment systems have shown to be successful in this field through diverse approaches that can be classified into two main …

Equivalency Testing For Two Formulations Of A Clinical Laboratory Control Material, Jessica M. Hart

Capstone Experience: Master of Public Health

Clinical laboratory control materials are an integral part of legally-mandated and highly regulated quality control protocols in all clinical laboratories. These controls ensure accurate performance of the laboratory testing and instrumentation used to produce medical test results for millions of patients. It is of clinical and public health interest to ensure the diagnostic test results which affect so many people are regulated by the most accurate and precise controls.

Formulation changes in control materials have the potential to impact laboratory quality control. In this study, data from two formulations of a hematology control were compared to assess equivalency of the …

Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim

McKelvey School of Engineering Graduate Student Theses & Dissertations

Electronic Health Records (EHR) are widely adopted and used throughout healthcare systems and are able to collect and store longitudinal information data that can be used to describe patient phenotypes. From the underlying data structures used in the EHR, discrete data can be extracted and analyzed to improve patient care and outcomes via tasks such as risk stratification and prospective disease management. Temporality in EHR is innately present given the nature of these data, however, and traditional classification models are limited in this context by the cross- sectional nature of training and prediction processes. Finding temporal patterns in EHR is …

Predicting Disease Progression Using Deep Recurrent Neural Networks And Longitudinal Electronic Health Record Data, Seunghwan Kim

McKelvey School of Engineering Graduate Student Theses & Dissertations

Electronic Health Records (EHR) are widely adopted and used throughout healthcare systems and are able to collect and store longitudinal information data that can be used to describe patient phenotypes. From the underlying data structures used in the EHR, discrete data can be extracted and analyzed to improve patient care and outcomes via tasks such as risk stratification and prospective disease management. Temporality in EHR is innately present given the nature of these data, however, and traditional classification models are limited in this context by the cross-sectional nature of training and prediction processes. Finding temporal patterns in EHR is especially …

Optometry's Contribution, Paul B. Freeman Od

Optometric Clinical Practice

Letter from the Editor-in-Chief

Does Patient-Provider Race/Ethnicity Concordance Impact Outcomes For Adults With Lupus?, Pamela C. Delis Phd, Rn, Cne, Inge B. Corless Phd, Rn, Fnap, Faan, Indigo Young Ms, Ccc-Slp, Mary W. Hildebrand Otd,Otr/L, Jessica G. Bell Ms, Amanda Tarbet Mslis

Journal of Health Disparities Research and Practice

Background: Health disparities exist among the 1.5 million Americans with lupus, with women of color bearing higher disease rates and burden. Complex reasons include genetics, comorbidities, and socioeconomics. These factors may lead to differences in health-related outcomes in lupus.

Aim: To determine if patient-provider racial/ethnic concordance plays a role in outcomes for adults with lupus.

Method: For this scoping review, the authors searched PubMed Medline and CINAHL using keywords and subject headings for lupus, race or ethnicity, and patient-health professional concordance.

Results: Despite an intentionally broadened search of literature, the authors identified a lack of studies examining the topic.

Conclusions: …

Mental Health In The School System: Providing Tools And Resources For Teachers, Hannah Skinner

Student Capstone Papers

This capstone project's aim was to look at the mental health needs of school aged children, and how Occupational Therapists can help to meet their needs in the school system. The doctoral student completed a background on mental health statistics and needs in children, and also completed a literature review on occupational therapy’s role in mental health and schools, mindfulness, and current practices in the United States.

A gap was identified after a literature search was completed: While the school systems understand mental health is an area that should be addressed, there is a gap in providing these tools and …

Exploring The Concurrent Validity Of The Indoor Mobility Pre-Driving Screen (Imps): A Comparison Of The Imps And Ef-Car Motion Driving Simulator., Nicholas T. Bolen

Student Capstone Papers

This paper details the results of a non-experimental assessment comparison study of concurrent validity in which the Indoor Mobility Pre-driving Screen (IMPS) is compared to an EF-Car Motion Driving Simulator. 36 participants completed both assessments concurrently. Collected data was analyzed using descriptive statistics and Pearson's r correlations. Results show low to moderate correlations between the compared assessments.

Health Information Management Careers: The Importance Of Skillset And Location On Salary, Danielle Sager

Applied Research Projects

Health information management is an engaging and dynamic occupational field that employs thousands of individuals throughout the United States across the spectrum of health care providing organizations. The ability to navigate these opportunities is influenced heavily by the location of available positions and the skillsets desired by employers. Through study of workforce development data and research in health information management one is able to determine the location and skillset of positions that will help distinguish oneself in a competitive marketplace that values not only education and experience, but the ability to lead in a field that is rapidly changing and …

The Relationship Between Optimism And Bmi In Generation Z – An Exploratory Investigation., Allison Tucker

Honors College Theses

Optimism is defined as explaining and expecting the future in a positive manner (Seligman, 2017). Biber and Czech (2015) have shown a significant negative correlation between optimism and overall BMI. PURPOSE: The purpose of this study is to examine differences between Optimism and Healthy, Overweight and Obese Generation Z university students. METHODS: This study is classified as aquantitative, quasi-experimental, cross-sectional descriptive study. There were 2287 participants- 986 male and 1285 female who were all aged 18-22. Participants attended a southeastern University and were enrolled in a required physical activity course. These students were classified in the Generation Z. Participants self-reported …

The Effectiveness Of Transfer Learning Systems On Medical Images, James Boit

Masters Theses & Doctoral Dissertations

Deep neural networks have revolutionized the performances of many machine learning tasks such as medical image classification and segmentation. Current deep learning (DL) algorithms, specifically convolutional neural networks are increasingly becoming the methodological choice for most medical image analysis. However, training these deep neural networks requires high computational resources and very large amounts of labeled data which is often expensive and laborious. Meanwhile, recent studies have shown the transfer learning (TL) paradigm as an attractive choice in providing promising solutions to challenges of shortage in the availability of labeled medical images. Accordingly, TL enables us to leverage the knowledge learned …

How Data Is Changing The World Of Healthcare, Cameron Marous

Honors Capstone Enhancement Presentations

No abstract provided.

Alumni Journal - Volume 91, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | Guest Editorial: Warren R. Peters '69
4 | From the President
6 | From the Deam

News
7 | This and That
10 | School of Medicine News
12 | Students
13 | Wedding Announcements
14 | Alumni News
15 | AIMS Report

APC 2020
16 | APC 2020 in Review: Featuring photos, alumni honorees, and more

Features
27 | Interview Feature: Columbus D. Batiste '98 shares his thoughts on healthy living
30 | Department Reports: Dermatology and Cardiothoracic Surgery: Harry Doa Jr., MD, and Anees J. Razzouk '82 report on their respective departments
and distinguished faculty …

Understanding And Identifying The Knowledge And Attitudes Of High School Coaches On Sport-Related Concussions, Marc A. Mortellaro

Seton Hall University Dissertations and Theses (ETDs)

Background and Purpose of the Study: Sport-related concussions are a major public health issue, particularly so in the setting of sports. Sports dominate American culture and with millions of athletes of all ages participating in these sports these athletes predispose themselves to the risks of sport-related concussions. High-school athletes are of particular interest because of the heightened risks of long-term consequences and of particular note second impact syndrome, which is a catastrophic injury primarily reported in the adolescent aged athlete. Appropriate concussion assessment and management is necessary for reducing the possibility of these long- term effects of concussions. Properly trained …

Kitchen Concentrations Of Fine Particulate Matter And Particle Number Concentration In Households Using Biomass Cookstoves In Rural Honduras, Megan L. Benka-Coker, Jennifer L. Peel, John Volckens, Nicholas Good, Kelsey R. Bilsback, Christian L'Orange, Casey Quinn, Bonnie N. Young, Sarah Rajkumar, Ander Wilson, Jessica Tryner, Sebastian Africano, Anibal B. Osorto Pinel, Maggie L. Clark

Health Sciences Faculty Publications

Cooking and heating with solid fuels results in high levels of household air pollutants, including particulate matter (PM); however, limited data exist for size fractions smaller than PM2.5 (diameter less than 2.5 μm). We collected 24-h time-resolved measurements of PM2.5 (n = 27) and particle number concentrations (PNC, average diameter 10–700 nm) (n = 44; 24 with paired PM2.5 and PNC) in homes with wood-burning traditional and Justa (i.e., with an engineered combustion chamber and chimney) cookstoves in rural Honduras.

The median 24-h PM2.5 concentration (n = 27) was 79 μg/m3 (interquartile range [IQR]: 44–174 μg/m3); traditional (n = 15): …

Conducting A 10-Minute Search For Evidence To Aid In Clinical Decision-Making, Mark Maceachern Mlis

The Journal of the Michigan Dental Association

This article is a continuation of the Journal’s series on implementing EBD process into clinical practice. The abundance of scientific literature can make it difficult to find the best evidence to answer a clinical question. This article presents strategies for conducting a 10-minute search for the best evidence, including:

• Developing a PICO question to focus the search.
• Using free search engines such as PubMed, Google Scholar, TRIP, PubMed Clinical Queries, Medline-Plus.gov, Epistemonikos, and other online resources such as published ADA Clinical Practice Guidelines.
• Using keywords with search properties, such as Boolean Operators and filters, to discover specific types of articles, …

Development Of A Diabetes Self-Management + Mhealth Program: Tailoring The Intervention For A Pilot Study In A Low-Income Setting In Mexico, Robin Whittemore, Mireya Vilar-Compte, Soraya Burrola-Méndez, Annel Lozano-Marrufo, Roberta Delvy, Mariana Pardo-Carrillo, Selene De La Cerda, Ninfa Pena-Purcell, Rafael Pérez-Escamilla

Department of Public Health Scholarship and Creative Works

Background: Type 2 diabetes (T2D) is a public health pandemic disproportionately affecting low- and middle-income countries. The purpose of this formative research was to adapt evidence-based diabetes self-management education programs to the context of Seguro Popular clinics in Mexico. A theory-based mHealth (pictorial text messaging) component was developed.

Method: Our formative research and development of the program protocol consisted of six phases: (1) interviews and focus groups with stakeholders on the challenges to T2D management, curriculum content needs, and the use of mHealth as a supplement to a DSME program; (2) review of the theoretical underpinning, curriculum, and interactive strategies …

Development Of Learning Objectives To Guide Enhancement Of Chronic Disease Prevention And Management Curricula In Undergraduate Medical Education, Michael Dekhtyar, Cristin Colford, Ebony Whisenant, Jill Huber, Eric Johnson, Patricia Thomas, Kate Kirley, Lauren Mazzurco, Arden D. Dingle, Valerie Terry, Senthil Rajasekaran, Laken Barkowski, Mrinalini Kulkarni-Date, David Henderson, Luann Wilkerson

School of Medicine Publications

Phenomenon: Chronic disease is a leading cause of death and disability in the United States. With an increase in the demand for healthcare and rising costs related to chronic care, physicians need to be better trained to address chronic disease at various stages of illness in a collaborative and cost-effective manner. Specific and measurable learning objectives are key to the design and evaluation of effective training, but there has been no consensus on chronic disease learning objectives appropriate to medical student education. Approach: Wagner’sChronic Care Model (CCM) was selected as a theoretical framework to guide development of an enhanced chronic …