Surgery Commons^™

Critical Assessment Of Outcomes In Acute Aortic Dissection (Type A) At A Community Hospital: A 10 Year Review, Timothy S. Misselbeck, James K. Wu Md, Stephen Deturk Ba, Michael F. Szwerc Md, Sanjay M. Mehta Md, Theodore G. Phillips Md, Gary W. Szydlowski Md, Raymond L. Singer Md

Department of Surgery

No abstract provided.

Value Of Routine Immunohistochemical (Ihc) Analysis Of Colorectal Cancer To Genetic Counseling Referrals, Avi Galler, Mychailo Fulmes Md, Phd, John Park, David Bub, Michael J. Weiss, Tara Namey, Ann Marie Augustyn, Robert Sinnott

Department of Surgery

No abstract provided.

Overview

Jefferson Surgical Solutions

The academic year 2011/2012 is now four months old, and we are off to a splendid start! We (a) have welcomed several new faculty members and a bolus of categorical interns (see below), (b) had a leadership transition at our Methodist Hospital, (c) are in growth mode at Methodist with initiatives in General Surgery, Vascular Surgery, Wound Care and Surgical Oncology (see the cover story), and (d) with the leadership of Dr. Nicholas Cavarocchi have seen remarkable growth in our adult ECMO program with outstanding clinical results and several research projects brought to fruition. Exciting times again this year at …

Endothelial Differentiation Of Adipose-Derived Stem Cells From Elderly Patients With Cardiovascular Disease., Ping Zhang, Neil Moudgill, Eric Hager, Nicolas Tarola, Christopher Dimatteo, Stephen Mcilhenny, Thomas Tulenko, Paul J Dimuzio

Department of Surgery Faculty Papers

Adipose-derived stem cells (ASCs) possess significant therapeutic potential for tissue engineering and regeneration. This study investigates the endothelial differentiation and functional capacity of ASCs isolated from elderly patients. Isolation of ASCs from 53 patients (50-89 years) revealed that advanced age or comorbidity did not negatively impact stem cell harvest; rather, higher numbers were observed in older donors (>70 years) than in younger. ASCs cultured in endothelial growth medium-2 for up to 3 weeks formed cords upon Matrigel and demonstrated acetylated-low-density lipoprotein and lectin uptake. Further stimulation with vascular endothelial growth factor and shear stress upregulated endothelial cell-specific markers (CD31, …

Use Of Geocoding And Us Census Data To Assess Determinants Of Outcome In Trauma Patients, Krista M. Goodman Md, John J. Hong Md, Sherrine Eid Mph, Leslie Baga Bsn, Ccrc, Michael M. Badellino Md, Mph, Facs, Michael D. Pasquale Md, Facs

Department of Surgery

No abstract provided.

Ct Scanning Is Sufficient To Clear The Cervical Spine Of Elderly Falls Less Than 5 Feet., Douglas Lehman Md, Rovinder S. Sandhu Md, Leslie Baga Bsn, Farheen Hussain Ms, John J. Hong Md

Administration & Leadership

No abstract provided.

Value Analysis: Perioperative Link In The Supply Chain, Gwenda L. Petrohoy Msn, Med, Rn, Cnor, Aaron D. Bleznak Md, Facs, Susan Toomey Cmrp

Department of Surgery

No abstract provided.

Results Of Re-Excision For Inadequate Margins Following Partial Mastectomy For Carcinoma Of The Breast, Aaron D. Bleznak Md, Facs, Christine W. Du Md, Samuel Steerman Md, Elizabeth Dellers Md

Department of Surgery

No abstract provided.

Conventional Aortic Valve Replacement For Elderly Patients In The Current Era., Kentaro Yamane, Hitoshi Hirose, Benjamin A Youdelman, Linda J Bogar, James T. Diehl

Department of Surgery Faculty Papers

BACKGROUND: Because of the rising expectation of prolonged life in the general population and the recent recognition of undertreated aortic valve disease in the elderly, updating the available results of aortic valve surgery is imperative, especially considering the rapid evolution of the transcatheter valve implantation procedure.

METHODS AND RESULTS: Between 1997 and 2010, 308 patients aged 70 years or older underwent aortic valve replacement (AVR) for aortic stenosis (AS). Short- and long-term results were analyzed and risk factors for long-term mortality were determined. Mean age was 78.5 years and 124 patients were aged 80 or older. Concomitant coronary artery bypass …

Surgical Site Infections In Gynecologic Oncology Patients: A Retrospective Study Of Patient Characteristics And Intraoperative Parameters, Christine C. Chen Md, Joanne N. Quiñones Md, Msce, Richard Boulay Md, M Bijoy Thomas Md, Martin Martino Md

Department of Obstetrics & Gynecology

No abstract provided.

Developing A Multidisciplinary Perioperative Safety Course, William Bond Md, Ms, Hope L. Johnson Msn, Rn, Cnor, Michael Pasquale Md, Facs, Fccm, Melissa B. Walsh Bs, Deborah Arnold Msn, Rn, Cmsrn, Matthew W. Leclair, Kelly L. Lago Ms, Jeanne P. Luke Msn, Rn, Cnor

Department of Emergency Medicine

No abstract provided.

Risk Factors Affecting Surgical Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries: A 10-Year Study, Bree Ann Young, James K. Wu, Martin E. Matsumura Md, Sanjay M. Mehta Md, Theodore G. Phillips Md, Michael F. Szwerc Md, Gary W. Szydlowski Md, Raymond L. Singer Md

Department of Medicine

No abstract provided.

Neo-Adjuvant Chemotherapy And Radiation Therapy In Patients With Stage Iiia (N2) Non-Small Cell Lung Cancer (Nsclc): A Retrospective Analysis With Lessons Learned, Eliot L. Friedman Md, Michael F. Szwerc Md, Charles Andrews Md, Robert Kruklitis Md, Kathleen A. Leies, Ferdy Santiago

Department of Medicine

No abstract provided.

Appendiceal Mucocele Intussusception, Christine W. Du Md, Rovinder S. Sandhu Md

Department of Surgery

No abstract provided.

Effect Of Histamine Blockade On Surgical Outcomes Of Perforated Diverticulitis, Matthew M. Philp Md, John S. Park Md

Department of Surgery

No abstract provided.

Experience Of Resident Assistant Does Not Influence Incidence Of Common Bile Duct Injuries During Laparoscopic Cholecystectomy, Ryan A. Lawless Md, Dale A. Dangleben Md, Charles Scagliotti Md, Judith A. Olenwine Ms, C-Tagme, John J. Hong Md, Michael M. Badellino Md

Department of Surgery

No abstract provided.

Laparoscopic Repair Of Incarcerated Obturator Hernia, Danielle Press Md, Dale A. Dangleben Md

Department of Surgery

No abstract provided.

Utilization Of Smartphones For The Enhancement Of Trauma Division Of Education, Ryan A. Lawless Md, Dale A. Dangleben Md, Rovinder S. Sandhu Md

Department of Surgery

No abstract provided.

The Clue To His Pancreatitis!, Malia Eischen Md, Dale A. Dangleben Md, Facs

Department of Surgery

No abstract provided.

Tuberculous Colitis, Firas G. Madbak Md, Dale A. Dangleben Md, Facs

Department of Surgery

No abstract provided.

Risk Factors Affecting Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries, Bree Ann Young, James K. Wu Md, Martin E. Matsumura Md, Timothy S. Misselbeck, Sanjay M. Mehta Md, Theodore G. Phillips Md, Michael F. Szwerc Md, Gary W. Szydlowski Md, Raymond L. Singer Md

Department of Surgery

No abstract provided.

Treatment Of Acute Aortic Dissection At A Community Hospital: A 10 Year Review Of Outcomes., Timothy S. Misselbeck, Stephen Deturk, Matthew Wilson, Theodore Phillips Md, Michael Szwerc Md, Sanjay Mehta Md, Gary Szydlowski Md, Raymond Singer Md, James Wu Md

Department of Surgery

No abstract provided.

Effect Of Preinjury Use Of Antiplatelet Agents In Patients With Isolated Traumatic Brain Injury, Danielle Cheeseman Md, David Milia Md, David Kashmer Md, Farheen Hussain Ms, John J. Hong Md, Robert D. Barraco Md

Department of Surgery

No abstract provided.

Complete Omental Torsion Associated With Left Inguinal Hernia: Case Report And Review Of The Literature, Patty T. Liu Md, Erik J. Teicher Md, Dale A. Dangleben Md

Department of Surgery

No abstract provided.

Caval Agenesis With Hypoplastic Left Kidney In A Trauma Patient On Warfarin For Deep Vein Thrombosis (Poster), Ryan A. Lawless Md, Dale A. Dangleben Md

Department of Surgery

No abstract provided.

Pp32 (Anp32a) Expression Inhibits Pancreatic Cancer Cell Growth And Induces Gemcitabine Resistance By Disrupting Hur Binding To Mrnas., Timothy K Williams, Christina L Costantino, Nikolai A Bildzukewicz, Nathan G Richards, David W Rittenhouse, Lisa Einstein, Joseph A Cozzitorto, Judith C Keen, Abhijit Dasgupta, Myriam Gorospe, Gregory E Gonye, Charles J Yeo, Agnieszka K Witkiewicz, Jonathan R Brody

Department of Surgery Faculty Papers

The expression of protein phosphatase 32 (PP32, ANP32A) is low in poorly differentiated pancreatic cancers and is linked to the levels of HuR (ELAV1), a predictive marker for gemcitabine response. In pancreatic cancer cells, exogenous overexpression of pp32 inhibited cell growth, supporting its long-recognized role as a tumor suppressor in pancreatic cancer. In chemotherapeutic sensitivity screening assays, cells overexpressing pp32 were selectively resistant to the nucleoside analogs gemcitabine and cytarabine (ARA-C), but were sensitized to 5-fluorouracil; conversely, silencing pp32 in pancreatic cancer cells enhanced gemcitabine sensitivity. The cytoplasmic levels of pp32 increased after cancer cells are treated with certain stressors, …

Back To The Suture: The Two 5 Mm Port Laparoscopic Appendectomy, James Lee Md, Margaret Moore Md, Dale A. Dangleben Md

Department of Surgery

No abstract provided.

A Severe Case Of Necrotizing Fasciitis Of The Abdomen: A Survivor Story, Karin Mcconville Md, Dale A. Dangleben Md, Rovinder S. Sandhu Md

Department of Surgery

No abstract provided.

One Year Survival With Poorly Differentiated Metastatic Pancreatic Carcinoma Following Chemoembolization With Gemcitabine And Cisplatin., Daniel B Brown, Carin F Gonsalves, Charles J Yeo, Agnes K Witkiewicz, Brian I Carr

Department of Radiology Faculty Papers

While hepatic arterial chemoembolization is efficacious for a number of malignancies, there is scant data regarding treatment of pancreatic adenocarcinoma. We report a complete radiographic response at one year from diagnosis of metastatic pancreatic carcinoma. Gemcitabine/cisplatin based chemoembolization may be of potential benefit for patients with liver-dominant metastases from pancreatic carcinoma. Given the typical survival of 6 months or less in this patient group with standard therapies, further research is warranted.

Overview-Charles J. Yeo, Md Samuel D. Gross Professor And Chair, Department Of Surgery

Jefferson Surgical Solutions

No abstract provided.