Surgery Commons^™

Foreign Body Removed Through Laparotomy: A Case Report And Literature Review, Kayla Nguyen, Duyen Quach, David Ortiz, Dominique Norris, Srinivas Ramireddy, Jody Smith

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Deficiency In Detail Among Ventral Hernia Repair Operative Notes And The Impact On Patient Outcomes, Alexys N. Ramos, Duyen Quach, Kayla Nguyen, Said Maldonado, Nicole B. Lyons, Jonathan S. Lall, Scott Zimmerle, Brendan Rosamond, Ashlynn Mills, Yoolim Alex Seo, Angelica C. Rodriguez, Mike Liang

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Surgical Management Of Massive Localized Lymphedema: A Case Report, Joseph Daodu, Alexys Ramos, Rainna Coelho, Natalia Cavagnaro, Mike Liang

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Profiling The Molecular And Clinical Landscape Of Glioblastoma Utilizing The Oncology Research Information Exchange Network Brain Cancer Database, Alexandra N. Demetriou, Frances Chow, David W. Craig, Michelle G. Webb, D. Ryan Ormond, James Battiste, Arnab Chakravarti, Howard Colman, John L. Villano, Bryan P. Schneider, James K. C. Liu, Michelle L. Churchman, Gabriel Zada

Markey Cancer Center Faculty Publications

Background. Glioblastoma exhibits aggressive growth and poor outcomes despite treatment, and its marked var- iability renders therapeutic design and prognostication challenging. The Oncology Research Information Exchange Network (ORIEN) database contains complementary clinical, genomic, and transcriptomic profiling of 206 glio- blastoma patients, providing opportunities to identify novel associations between molecular features and clinical outcomes.

Methods. Survival analyses were performed using the Logrank test, and clinical features were evaluated using Wilcoxon and chi-squared tests with q-values derived via Benjamini-Hochberg correction. Mutational analyses util- ized sample-level enrichments from whole exome sequencing data, and statistical tests were performed using the one-sided Fisher Exact test …

The Management And Outcomes Of Hepatocellular Carcinoma In Sub-Saharan Africa: A Systematic Review., Sanju Sobnach, Urda Kotze, Wendy Spearman, Mark Sonderup, Pueya Nashidengo, Chikwendu Ede, Elie Keli, Onesai Chihaka, Luiz Zerbini, Yifan Li, Karan Gandhi

General Surgery, East Africa

Background: Hepatocellular carcinoma (HCC) is a leading cause of mortality in sub-Saharan Africa (SSA). This systematic review aimed to appraise all population-based studies describing the management and outcomes of HCC in SSA.

Methods: A systematic review based on a search in PubMed, PubMed Central, Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), AfricaWide and Cochrane up to June 2023 was performed. PRISMA guidelines for systematic reviews were followed. The study protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) (registration no: CRD42022363955).

Results: Thirty-nine publications from 15 of 48 SSA countries were …

Pilot Quality Improvement Project To Update Surgeon Preference Cards Of A Community Hospital's Orthopedic Service, Jessica R. Mitchell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Implementation of a Pilot Quality Improvement Project to Update Surgeon Preference Cards

of a Community Hospital’s Orthopedic Service

Jessica R. Mitchell

Problem Statement: Over time, surgeons change preferences for surgical equipment, and their preference cards need updating. Failure to update preference cards leads to impaired staff communication, opening of unnecessary equipment, excess waste, increased cost to patients and facilities, and potential threats to patient safety.

Background: Members of the orthopedic surgical team in a community hospital in suburban West Virginia wanted to establish a process to regularly update outdated surgeon preference cards (SPC) for several common orthopedic procedures. The …

Power Safety Plan Checklist As An Intervention In The Operating Room, Scott John Fankhauser

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Power Safety Plan Checklist as an Intervention in the Operating Room

Scott J. Fankhauser

Background: Intraoperative power failures (IOPF) force anesthesia providers to quickly make decisions to prevent patient harm when equipment does not operate as designed. Familiarity with alternative methods is critical during this decision process to deliver high-quality care during IOPF events. Purpose: The purpose of this project was to assess the impact of a checklist on anesthesia providers’ perceptions regarding continuation of care during an IOPF. Interventions: Pre- and post-intervention surveys were conducted during a simulation and education setting for annual competencies. Methods: The study …

Postoperative Antibiotics For Diabetic Patients With Complicated Appendicitis, Bill D. Pope Iii, Alejandro J. Candil

MEDI 9331 Scholarly Activities Clinical Years

This retrospective study, conducted at Valley Baptist Medical Center from March 14, 2020, to December 3, 2023, explores the impact of postoperative antibiotics on diabetic patients with complicated appendicitis. Out of 494 appendectomy patients, 17 diabetic patients with complicated appendicitis were analyzed. Of these, 15 received postoperative antibiotics, with 2 developing infections (13%), while the 2 did not receive postoperative antibiotics and remained infection-free. The study acknowledges limitations in sample size and the subjective nature of defining complicated appendicitis. These findings contribute to ongoing discussions on postoperative antibiotic practices, particularly in diabetic patients with complicated appendicitis.

A Rare Case Of Breast Carcinoma Metastasis Into A Meningioma In A 64-Year-Old Female Patient, Edwin Mogere, Miriam Mutebi, Allan Njau, Manel Haj Mansour

General Surgery, East Africa

This report discusses the occurrence of tumor-to-tumor metastasis—an atypical phenomenon in oncology where a secondary malignancy develops within an existing primary tumor. The case of a 64-year-old woman is presented, who, with a history of stage II invasive ductal carcinoma of the breast treated with mastectomy and chemoradiotherapy, developed neurological symptoms indicative of a secondary brain tumor. MRI and subsequent histopathological analysis post-craniotomy confirmed a meningioma with a metastatic breast carcinoma, demonstrating the clinical importance of considering tumor-to-tumor metastasis in similar patient histories.

Early Outcome Of Mini-Mvs Surger Y Elsherif Et Al., Mahmoud Abdullghany Amin Elsherif, Rasha Hosny, Mohamed Ramadan Mohamed

Journal of Medicine in Scientific Research

Background: The conventional incision adopted to for mitral valve replacement is the full sternotomy, with proved over time and experience to be a simple and safe method. Minimal invasive mitral valve surgery (Mini-MVS) is an alternative approach for elective mitral surgeries that proved over the last years to be a promising option.

Aim of the study: Assessment of the early outcome of minimally invasive mitral valve surgery with or without tricuspid surgery.

Methods: A retrospective study on 100 consecutive patients who underwent minimal invasive mitral valve surgery from January 2021 to June 2023 at National Heart Institute in Egypt.

Results: …

Anterior Circulation Location-Specific Results For Stent- Assisted Coiling – Carotid Versus Distal Aneurysms: 1- Year Outcomes From The Neuroform Atlas Stent Pivotal Trial, Ricardo A. Hanel, Gustavo M. Cortez, Brian T. Jankowitz, Eric Sauvageau, Amin Aghaebrahim, Eugene Lin, Ashutosh P. Jadhav, Bradley Gross, Ahmad Khaldi, Rishi Gupta, Donald Frei, David Loy, Lori Lyn Price, Steven W. Hetts, Osama O. Zaidat, Atlas Investigators

Neurology Faculty Publications

Background The Neuroform Atlas Stent System is an established treatment modality for unruptured anterior and posterior circulation intracranial aneurysms. Location-specific results are needed to guide treatment decision- making. However, it is unclear whether there are differences in safety and efficacy outcomes between carotid and more distal anterior circulation aneurysms. Methods The ATLAS IDE trial was a prospective, multicenter, single- arm, open-label interventional study that evaluated the safety and efficacy of the Neuroform Atlas Stent System. We compared differences in efficacy and safety outcomes of proximal internal carotid artery (ICA) versus distal and bifurcation anterior circulation aneurysms.

Results Of 182 cases, …

The Unequal Distribution Of Social Risk For Black Men Across The Life-Span. A Novel Framework., Waleed Y. Sami

Adultspan Journal

This conceptual overview offers a comprehensive overview of systemic pathways that negatively impact the mental health of Black Men throughout their lives. Our argument highlights the importance for counselors and mental health professionals to utilize a thorough social risk assessment that considers these pathways in order to effectively address the mental health needs of Black Men while fostering positive working relationships. This overview strongly advocates for the use of context and structural determinants when evaluating mental health symptoms. Without an appropriate understanding of social risk and determinants, counselors may inadvertently perpetuate disparities by decontextualizing symptomology, and reproducing racist discourse.

The Effects Of Social Support On Recovery Outcomes Of Hip Fracture Patients, Preshecca Ragavan

Williams Honors College, Honors Research Projects

This literature review, completed under the guidance of Ms. Anuja Sarode-Paciorek from Summa Health - Akron, will investigate the effects of social support on the recovery outcomes of hip fracture patients. As part of this literature review, I will collect and analyze several scientific journal articles previously published on this topic to gain an overview of what prior knowledge clinical researchers have already gathered about this topic. As part of the analyses, each article will be thoroughly read and briefly summarized. Then, these summaries will be used to compile a list of a few strengths and a list of a …

Suprachoroidal Space Injection Technique Expert Panel Guidance, Charles C. Wykoff, Robert L. Avery, Mark R. Barakat, David S. Boyer, David M. Brown, Alexander J. Brucker, Emmett T. Cunningham Jr., Jeffrey S. Heier, Nancy M. Holekamp, Peter K. Kaiser, Arshad M. Khanani, Judy E. Kim, Hakan Demirci, Carl D. Regillo, Glenn C. Yiu, Thomas A. Ciulla

Wills Eye Hospital Papers

Purpose:

To develop professional guidelines for best practices for suprachoroidal space (SCS) injection, an innovative technique for retinal therapeutic delivery, based on current published evidence and clinical experience.

Methods:

A panel of expert ophthalmologists reviewed current published evidence and clinical experience during a live working group meeting to define points of consensus and key clinical considerations to inform the development of guidelines for in-office SCS injection.

Results:

Core consensus guidelines for in-office SCS injection were reached and reported by the expert panel. Current clinical evidence and physician experience supported SCS injection as a safe and effective method for delivering retinal …

Biomechanical Outcomes Of Distinct Tka Surgical Alignments And Implant Designs, Alexis Kathleen Nelson-Tranum

Theses and Dissertations (ETD)

Introduction. Total knee arthroplasty (TKA) has advanced over the past two decades from traditional post-operative neutral alignment methods with an overall goal of implant longevity to ones that are more personalized to better replicate individual native knee kinematics. Personalizing TKA knee kinematics to better replicate a patient’s native knee kinematics has evolved in response to a reported 20% dissatisfaction by patients with their TKA. These personalization advancements include innovations in surgical alignment techniques include the kinematic alignment (KA) and joint line obliquity (JLO) restoration, in contrast to the mechanical alignment (MA) technique that places everyone into the same mold. Additionally, …

Green Synthesis Of Zinc Oxide Nanoparticles From Althaea Officinalis Flower Extract Coated With Chitosan For Potential Healing Effects On Diabetic Wounds By Inhibiting Tnf-Α And Il-6/Il-1Β Signaling Pathways, Sammar Fathy Elhabal, Nashwa Abdelaal, Saeed Abdul Kareem Saeed Al-Zuhairy, Mohamed Fathi Mohamed Elrefai, Ahmed Mohsen Elsaid Hamdan, Mohamed Mansour Khalifa, Sandra Hababeh, Mohammad Ahmad Khasawneh, Gehad M Khamis, Jakline Nelson, Passant M Mohie, Rania A Gad, Amira Rizk, Soad L Kabil, Mohamed Kandeel El-Ashery, Bhaskara R Jasti, Nahla A Elzohairy, Tayseer Elnawawy, Fatma E Hassan, Mohamed A El-Nabarawi

Faculty, Staff and Students Publications

BACKGROUND: Diabetes Mellitus is a multisystem chronic pandemic, wound inflammation, and healing are still major issues for diabetic patients who may suffer from ulcers, gangrene, and other wounds from uncontrolled chronic hyperglycemia.

METHOD AND RESULTS: First, develop eco-friendly green Zinc Oxide Nanoparticles (ZnO-NPs) and incorporate them into a 2% chitosan (CS) gel. In-vitro study performed by UV-visible spectrum analysis showed a sharp peak at 390 nm, and Energy-dispersive X-ray (EDX) spectrometry showed a peak of zinc and oxygen. Besides, Fourier transforms infrared (FTIR) was used to qualitatively validate biosynthesized ZnO-NPs, and transmission electron microscope (TEM) showed spherical nanoparticles with mean …

Revolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery Of Cyclosporine And Dithranol: In-Vitro, Ex-Vivo, And In-Vivo Studies, Sammar Fathy Elhabal, Nashwa Abdelaal, Saeed A S Al-Zuhairy, Mohamed Fathi Mohamed Elrefai, Mohamed Mansour Khalifa, Mohammad Ahmad Khasawneh, Ahmed Mohsen Elsaid Hamdan, Passant M Mohie, Rania A Gad, Soad L Kabil, Mohamed Kandeel El-Ashery, Bhaskara R Jasti, Nahla A Elzohairy, Nehal Elfar, Tayseer Elnawawy, Fatma E Hassan, Mohamed Ahmed El-Nabarawi

Faculty, Staff and Students Publications

PURPOSE: Improving the treatment of psoriasis is a serious challenge today. Psoriasis is an immune-mediated skin condition affecting 125 million people worldwide. It is commonly treated with cyclosporine-A (CsA) and dithranol (DTH). CsA suppresses the activation of T-cells, immune cells involved in forming psoriatic lesions. Meanwhile, DTH is a potent anti-inflammatory and anti-proliferative drug that effectively reduces the severity of psoriasis symptoms such as redness, scaling, and skin thickness. CsA and DTH belong to BCS class II with limited oral bioavailability. We aim to develop a drug delivery system for topical co-delivery of CsA and DTH, exploring its therapeutic potential. …

Pre-Clinical Protective Potentials Of Carica Papaya Constituents In Experimentally Induced Anemia, Hassan Abdulsalam Adewuyi, Adamu Yusuf Kabiru, Hadiza Lami Muhammad, Halimat Yusuf Lukman, Mayowa Solomon Owolabi, Ibrahim Jonathan, Ahmed M El-Gazzar, Mohamed H Mahmoud, Gaber El-Saber Batiha, Bashir Lawal

Faculty, Staff and Students Publications

OBJECTIVE: Anemia is a pathological condition characterized by reduced oxygen bioavailability and/or changes in hematological parameters. This study investigated the anti-anemic activities of

METHOD: Twenty-seven rats were randomized into nine groups of three rats as follows; group 1 was the normal (non-induced) group, 2-9 were anemic rats administered 1 mL distilled water, standard drug (3 mg/kg body weight (bw) ferrous sulphate), 100, 300 and 500 mg/kg bw of crude methanolic extract of CP (CMECP) of the leaf and 100, 300 and 500 mg/kg bw of CMECP of the seed respectively in the first stage of the study. In the second …

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis In An Orthotopic Liver Transplant Recipient: A Case Report, Chun-Sing Huang, Emily Strouphauer, Christine O'Mahony, Nhu T N Galván, Ronald Cotton, John Goss, Abbas Rana

Faculty, Staff and Students Publications

Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare spectrum of acute, mucocutaneous drug reactions characterized by epidermal necrosis of the skin and mucous membranes with progressive multiorgan failure. Cutaneous presentation of SJS/TEN is similar to that of acute graft-versus-host disease, creating a diagnostic dilemma in solid-organ transplant recipients presenting with diffuse, erythematous eruptions, skin sloughing, and systemic sequelae, reflective of both diseases. This case report details a 48-year-old woman post-orthotopic liver transplantation (OLT) who developed a diffuse, painful, morbilliform rash with progressive desquamation, along with corresponding pathological analysis indicative of SJS/TEN. There are few documented reports of SJS/TEN in solid-organ …

Bridging The Gap: Assessing Cmv Dnaemia In Kidney Transplant Recipients With Previous Solid Organ Transplants, Goni Katz-Greenberg, Julie M Steinbrink, Krishna Shah, Jennifer S Byrns

Faculty, Staff and Students Publications

Cytomegalovirus (CMV) infection poses a significant threat to solid organ transplant (SOT) recipients and can lead to various complications and adverse outcomes. In an effort to prevent CMV infection, it is common to utilize prophylactic strategies, including antiviral medications such as valganciclovir, especially for high-risk patients. Risk factors for CMV infection in kidney transplant recipients (KTRs) include CMV mismatch between donor and recipient (i.e., donor positive, recipient negative), and intensity of immunosuppression, such as the use of T-cell depleting agents. However, little attention has been given to KTRs with a history of prior SOTs, despite their prolonged exposure to immunosuppressive …

The 2018 World Cancer Research Fund (Wcrf)/American Institute For Cancer Research (Aicr) Score And Diabetes Risk In The Diabetes Prevention Program Outcomes Study (Dppos), Danny Ramzy, Nicholas Ray

Faculty, Staff and Student Publications

No abstract provided.

Activation Of Mechanoreceptor Piezo1 Inhibits Enteric Neuronal Growth And Migration, Chioma Moneme, Oluyinka O Olutoye, Michał F Sobstel, Yuwen Zhang, Xinyu Zhou, Jacob L Kaminer, Britney A Hsu, Chengli Shen, Arabinda Mandal, Hui Li, Ling Yu, Swathi Balaji, Sundeep G Keswani, Lily S Cheng

Faculty, Staff and Students Publications

INTRODUCTION: Dysfunction of the enteric nervous system (ENS) is linked to a myriad of gastrointestinal (GI) disorders. Piezo1 is a mechanosensitive ion channel found throughout the GI tract, but its role in the ENS is largely unknown. We hypothesize that Piezo1 plays an important role in the growth and development of the ENS.

METHODS: Enteric neural crest-derived progenitor cells (ENPC) were isolated from adult mouse intestine and propagated in culture as neurospheres. ENPC-derived neurons were then subject to

RESULTS: Though stretch did not cause upregulation of Piezo1 expression in enteric neurons, both stretch and Piezo1 activation produced similar alterations in …

Evaluating Outcomes Post-Adoption Of Reck Solution For Total Shoulder Arthroplasties: A Retrospective Quality Analysis, Benjamin Levi Tillis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Evaluating Outcomes Post-adoption of RECK Solution for Total Shoulder Arthroplasties: A Retrospective Quality Analysis

Benjamin Tillis

Introduction: Local infiltration analgesia (LIA) has become an integral part of postoperative pain relief for West Virginia University (WVU) Medicine’s total joint arthroplasty procedures. However, not all LIAs are the same. Liposomal bupivacaine has a unique mechanism of delivery which could potentially lead to longer lasting effects. Ropivacaine, epinephrine, clonidine, and ketorolac (RECK) solution offers a multimodal approach to enhancing the duration of effect for the LIA. In 2022, WVU Medicine switched from liposomal bupivacaine to the RECK solution for total joint …

Impact Of Tiered Implementation Of Clinical Decision Support System For Acute Kidney Injury And Nephrotoxin Exposure In Cardiac Surgery Patients, Christopher M. Justice Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).

Objective: To determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.

Methods: We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023. A passive electronic AKI alert was activated in Jul 2020, followed by an electronic nephrotoxin alert in March 2023. In this alert, active nephrotoxic medication orders resulted in …

2024 Canadian Surgery Forum: Sept. 25-28, 2024., Christine Li, Michael Guo, Ahmer Karimuddin, Michael Guo, Christine Li, Ahmer Karimuddin, Jason Sutherland, Bright Huo, Tyler Mckechnie, Monica Ortenzi, Yung Lee, Stavros Antoniou, Julio Mayol, Hassaan Ahmed, Vanessa Boudreau, Karim Ramji, Cagla Eskicioglu, Pieter De Jager, David Urbach, Meredith Poole, Aghiles Abbad, Hussain Al-Shamali, Zainab Al-Faraj, Chuck Wen, Radu Pescarus, Robert Bechara, Dennis Hong, Lily J Park, Maura Marcucci, Sandra Ofori, Jessica Bogach, Pablo E Serrano, Marko Simunovic, Ilun Yang, Margherita Cadeddu, Michael J Marcaccio, Flavia K Borges, Rahima Nenshi, P J Devereaux, Peter Urbanellis, Joanne Douglas, Evan Nemeth, James Ellsmere, Richard Spence, Joshua Cunningham, Ryan Falk, Tom Skinner, Nicole Ebert, Lauren Galbraith, Mark Prins, Shahrzad Joharifard, Emilie Joos, Adele Orovec, Lynn Lethbridge, Richard Spence, Marius Hoogerboord, Heather Stuart, Anne-Marie Bergeron, Ilun Yang, Jessica Bogach, Laura Nguyen, Clare Reade, Lua Eiriksson, Michelle Morais, Gillian Hanley, Sarah Mah, Karanbir Brar, Keri A Seymour, Shaina R Eckhouse, Ranjan Sudan, Jacob A Greenberg, Dana Portenier, James J Jung, Anne Light, Brittany Dingley, Megan Delisle, Sameer Apte, Ranjeeta Mallick, Trevor Hamilton, Heather Stuart, Martha Talbot, Gregory Mckinnon, Evan Jost, Eve Thiboutot, Carolyn Nessim, Neha Katote, Ashley Drohan, Richard Spence, Katerina Neumann, Ge Shi, Regina Leung, Christina Lim, Matthew Van Oirschot, Aaron Grant, Sarah Knowles, Julie Ann Van Koughnett, Karine Brousseau, Leah Monette, Daniel Mcisaac, Christopher Wherrett, Ranjeeta Mallick, Aklile Workneh, Tim Ramsay, Alan Tinmouth, Julie Shaw, François Martin Carrier, Dean Fergusson, Guillaume Martel, Matthew Cornacchia, Victoria Ivankovic, Shahad Abdulkhaleq Mamalchi, Dexter Choi, Peter Glen, Maher Matar, Fady Balaa, Natasha Caminsky, Sarah Mashal, Nathalie Boulanger, Larry Watt, Jonathon Campbell, Jeremy Grushka, Paola Fata, Evan Wong, Michael Guo, Ahmer Karimuddin, Jason Sutherland, Christine Li, Wenjie Lin, Ahmer Karimuddin, Bright Huo, Elisa Calabrese, Sunjay Kumar, Bethany Slater, Danielle S Walsh, Wesley Vosburg, Uzair Jogiat, Simon Turner, Vickie Baracos, Dean Eurich, Heather Filafilo, Eric Bedard, Sam Khan, Tom Waddell, Kazuhiro Yasufuku, Andrew Pierre, Shaf Keshavjee, Elliot Wakeam, Laura Donahoe, Marcelo Cypel, Najib Safieddine, Michael Ko, Natasha Leighl, Jamie Feng, Jonathan Yeung, Marc De Perrot, Alexandra Salvarrey, Negar Ahmadi, Carmine Simone, Gazala Sayf, David Parente, Victoria Cheung, Mary R Rabey, Michael Cabanero, Lisa W Le, Christodoulos Pipinikas, Amber Chevalier, Richard Chaulk, David Sahai, Richard Malthaner, Mehdi Qiabi, Dalilah Fortin, Richard Inculet, Rahul Nayak, John Campbell, Peter White, Adam Bograd, Alexander Farivar, Brian Louie, Geraint Berger, Daniel French, Simon Houston, Flyn Gallardo, Bryce Macek, Richard Liu, Biniam Kidane, Nader M Hanna, Yogita S Patel, Ikennah Browne, Esther Provost, Forough Farrokhyar, Ehsan Haider, Waël C Hanna, Garrett Johnson, George Okoli, Nicole Askin, Ahmed Abou-Setta, Harminder Singh, Alexandra Coxon-Meggy, Julie Cornish, Lars Icat Study Management Group, Sahil Sharma, Jigish Khamar, Jo-Anne Petropolous, Amandeep Ghuman, Wenjie Lin, Christine Li, Carl Brown, Terry Phang, Manoj Raval, Amandeep Ghuman, Elizabeth Clement, Ahmer Karimuddin, Tyler Mckechnie, Jigish Khamar, Christopher Chu, Amin Hatamnejad, Ghazal Jessani, Yung Lee, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Giancarlo Sticca, Madeleine Poirier, Jean-François Tremblay, Jean-François Latulippe, Yves Bendavid, Jean-Sébastien Trépanier, Ariane Lacaille-Ranger, Margaret Henri, Tyler Mckechnie, Tania Kazi, Victoria Shi, Shan Grewal, Ahmed Aldarraji, Kelly Brennan, Sunil Patel, Nalin Amin, Aristithes Doumouras, Sameer Parpia, Cagla Eskicioglu, Mohit Bhandari, Gaurav Talwar, Tyler Mckechnie, Jigish Khamar, Luke Heimann, Swati Anant, Cagla Eskicioglu, Victoria Shi, Tyler Mckechnie, Swati Anant, Moeiz Ahmed, Sahil Sharma, Gaurav Talwar, Dennis Hong, Cagla Eskicioglu, Tania Kazi, Tyler Mckechnie, Yung Lee, Rehab Alsayari, Gaurav Talwar, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Lily J Park, Husein Moloo, Tim Ramsay, Kednapa Thavorn, Justin Presseau, Terry Zwiep, Guillaume Martel, P J Devereaux, Robert Talarico, Daniel I Mcisaac, Madeline Lemke, Wenjie Lin, Carl Brown, Elizabeth Clement, Anu Ghuman, Terry Phang, Manoj Raval, Ahmer Karimuddin, Christine Li, Wenjie Lin, Elizabeth Clement, Amandeep Ghuman, Cameron Hague, Ahmer Karimuddin, P Terry Phang, Manoj Raval, Pari Tiwari, Patrick Vos, Carl Brown, Alessandro Ricci, Ameer Farooq, Sunil Patel, Kelly Brennan, Vanessa Wiseman, Tyler Mckechnie, Allison Keeping, Paul Johnson, Heidi Bentley, Karim Messak, Jessica Bogach, Gregory Pond, Shawn Forbes, Vanja Grubac, Scott Tsai, Christian Van Der Pol, Marko Simunovic, Adom Bondzi-Simpson, Ramy Behman, Tiago Ribeiro, Sheron Perera, Aisha Lofters, Rinku Sutradhar, Rebecca Snyder, Callisia Clarke, Natalie Coburn, Julie Hallet, Natasha Caminsky, Alex Chen, Jeongyoon Moon, Paul Brassard, Daniel Marinescu, Teodora Dumitra, Ebram Salama, Carol-Ann Vasilevsky, Marylise Boutros, Kelly Brennan, Tyler Mckechnie, Vanessa Wiseman, Alessandro Ricci, Ameer Farooq, Sunil Patel, Tania Kazi, Tyler Mckechnie, Ghazal Jessani, Victoria Shi, Niv Sne, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Manisha Jogendran, Jennifer Flemming, Maya Djerboua, Martin Korzeniowski, Brooke Wilson, Shaila Merchant, Sean Bennett, Kala Hickey, Stephanie Gill, Zoë Breen, Kaitlyn Harding, Hannah Yaremko, Patti Power, Alex Mathieson, David Pace, Joannie Neveu, Sean Bennett, Brooke Wilson, Nan Chen, Weidong Kong, Sunil Patel, Christopher Booth, Shaila Merchant, Sean Bennett, Georgia Nelson, Nouf Almarzooqi, Manisha Jogendran, Maya Djerboua, Brooke Wilson, Jennifer Flemming, Shaila Merchant, Lily J Park, Carol Wang, Vicki Archer, Tyler Mckechnie, Dan Cohen, Jessica Bogach, Marko Simunovic, Pablo E Serrano, Rodney H Breau, Paul Karanicolas, P J Devereaux, Georgia Nelson, Nouf Almarzooqi, Shaila Merchant, Sean Bennett, Janyssa Charbonneau, Mai-Kim Gervais, Alexandre Brind'amour, Narcisse Singbo, Mikaël Lefebvre Soucisse, Lucas Sidéris, Guy Leblanc, Jean-François Tremblay, Pierre Dubé, Ekaterina Kouzmina, Matthew Castelo, Nicole Look Hong, Julie Hallet, Natalie Coburn, Frances Write, Lena Nguyen, Sonal Gandhi, Katarzyna Jerzak, Andrea Eisen, Amanda Roberts, Dejan Vidovic, Brianne Cruickshank, Lucy Helyer, Carman Giacomantonio, Zuhaib Mir, Matheus Faleiro, Stephanie Hiebert, Scott Livingstone, Mark Walsh, Boris Gala-Lopez, Sukhdeep Jatana, Daniel Krys, Uzair Jogiat, Janice Kung, Kevin Verhoeff, Tori Lenet, François Martin Carrier, Karine Brousseau, Franck Vandenbroucke-Menu, Yves Collin, Richard W D Gilbert, Maja Segedi, Jad Abou Khalil, Kimberly A Bertens, Fady Balaa, Dean A Fergusson, Guillaume Martel, Christopher Wherrett, Katlin Mallette, Leah Monette, Aklile Workneh, Monique Ruel, Elham Sabri, Heather Maddison, Melanie Tokessym, Patrick B Y Wong, Luc Massicotte, Michaël Chassé, Michel-Antoine Perrault, Élodie Hamel-Perreault, Jeieung Park, Shirley Lim, Véronique Maltais, Philemon Leung, Timothy Ramsay, Alan Tinmouth, Zofia Czarnecka, Nidheesh Dadheeech, Rena Pawlick, Haide Razavy, James Shapiro, Panthea Pouramin, Susan Allen, Boris Gala-Lopez, Nawal Amhis, Rachel Liu Hennessey, Yuwei Yang, Rochelle Guan, Yolanda Zhang, Adam Meneghetti, Chieh Chiu, Dhuvaraha Srikrishnaraj, Jeffrey Hawel, Christopher Schlachta, Ahmad Elnahas, Ayse Yilbas, Marguerite Mainprize, Anton Svendrovski, Christoph Paasch, Fernando Spencer Netto, Jigish Khamar, Tyler Mckechnie, Amin Hatamnejad, Yung Lee, Bright Huo, Edward Passos, Niv Sne, Cagla Eskicioglu, Dennis Hong, Sean Bennett, Jennifer Flemming, Maya Djerboua, Vanessa Wiseman, Jonah Moore, Peter Szasz, Sulaiman Nanji, Jonah Moore, Vanessa Wiseman, Peter Szasz, Isis Lunsky, Sulaiman Nanji, Jennifer A Flemming, Sean Bennett, Sandra Mckeown, Omar Mouhammed, Colton Gibb, Kevin Verhoeff, Michael Kim, Matt Strickland, Ram Anantha, Ilinca Georgescu, Yung Lee, Thomas Shin, Lea Tessier, Arshia Javidan, James Jung, Dennis Hong, Tyler Mckechnie, Andrew Strong, Matthew Kroh, Jerry Dang, Muhammad Faran, Tyler Mckechnie, Emma O'Callaghan, Sama Anvari, Taylor Hughes, Mark Crowther, Mehran Anvari, Aristithes Doumouras, Amin Andalib, Ali Safar, Philippe Bouchard, Sebastian Demyttenaere, Olivier Court, Simran Parmar, Brianna Brand, Noah Switzer, Richdeep Gil, Sunawer Aujla, Morgan Schellenberg, Natthida Owattanapanich, Brent Emigh, Jan-Michael Van Gent, Tanya Egodage, Patrick B Murphy, Chad Ball, Audrey L Spencer, Kelly N Vogt, Jessica A Keeley, Stephanie Doris, Kenji Inaba, Jordan Nantais, Nancy Baxter, Refik Saskin, Andrew Calzavara, David Gomez, Alex Le, Philip Dawe, Morad Hameed, Amir Hassanpour, Eran Shlomovitz, David Gomez, Eisar Al-Sukhni, Vanessa Wiseman, Sunil Patel, Sean Bennett, Zuhaib Mir, Stephanie Roberts, Harvey Hawes, Khalil Merali, Rachel Morris, Marc De Moya, Todd Neideen, Andrew Kastenmeier, Lewis Somberg, Dan Holena, Patrick Murphy, Jordan Nantais, Nancy Baxter, Refik Saskin, Andrew Calzavara, David Gomez, Asad Naveed, Umang Deshpande, David Gomez, Joao Rezende-Neto, Najma Ahmed, Andrew Beckett

Surgery Articles

No abstract provided.

Phenytoin-Induced Cerebellar Atrophy: A Case For Reversibility Of Neurological Decline., Edwin Mogere, Davis Cheruiyot, Nassiuma Manakhe

General Surgery, East Africa

This case serves as a reminder of the infrequent, yet consequential occurrence of cerebellar degeneration linked to phenytoin usage. Whilst emphasizes the importance of monitoring patients on long-term phenytoin therapy, and it further suggests considering employing bedside imaging tools such as Ultrasound fusion imaging for follow-up of patients at risk of this type of disorder. We present a case study involving a 23-year-old woman who experienced significant neurological impairment resulting in severe cerebellar atrophy while undergoing phenytoin treatment. On cessation of phenytoin, the patient exhibited improvement with enhanced cerebellar function.

Promising Response Of Olaparib In Patient With Germline Atm-Mutated Metastatic Gastric Cancer, Kok Hoe Chan, Darius Rutazanaa, Curtis Wray, Nirav Thosani, Victor Yang, Putao Cen

Faculty, Staff and Student Publications

Gastric cancer ranks as the fifth leading cause of global cancer incidences, exhibiting varied prevalence influenced by geographical, ethnic, and lifestyle factors, as well as

Comprehensive Analysis Of Craniopharyngioma: Epidemiology, Clinical Characteristics, Management Strategies, And Role Of Radiotherapy, Amir Mushtaq, Mohsin Fayaz, Abdul Rashid Bhat, Abbas F Abdul Hussein, Gianluca Ferini, Giuseppe Emmanuele Umana, Gianluca Scalia, Feroze Ahmad Mir, Aizul Khursheed, Bipin Chaurasia

Faculty, Staff and Student Publications

BACKGROUND/AIM: Craniopharyngiomas pose challenges in diagnosis and management due to their rare occurrence and diverse clinical manifestations. This study aimed to provide a comprehensive analysis of cranio-pharyngioma, including its epidemiological trends, clinical presentations, radiological characteristics, surgical interventions, and the role of radiotherapy.

PATIENTS AND METHODS: A retrospective observational study was conducted on 23 patients diagnosed with craniopharyngioma at our hospital from August 2017 to July 2019. Data regarding demographics, clinical presentation, radiological findings, surgical interventions, and adjuvant therapies were collected and analyzed.

RESULTS: Craniopharyngiomas exhibited a bimodal age distribution, with peaks in childhood and late adulthood. Clinical presentations varied between …

Ergonomics Of Various Modalities For Ear Surgery, Matthew E Lin, Sheng Zhou, Seiji Kakeheta, Tsukasa Ito, Seiji B Shibata

Faculty, Staff and Student Publications

OBJECTIVE: Evaluate ergonomic differences of various modalities for performing middle ear surgery.

STUDY DESIGN: Observational study.

SETTING: Two academic tertiary care centers.

METHODS: Attending physicians and residents performing middle ear surgery were photographed intraoperatively. Intraoperative photographs were analyzed using the validated Rapid Upper Limb Assessment (RULA) tool to measure musculoskeletal disease (MSD) risk. Descriptive statistics and significance testing were used to characterize and compare ergonomic differences between surgical modalities. Multivariable ordinal regression was performed to assess factors associated with increased MSD risk, as determined by the final RULA score.

RESULTS: Most of our 110 intraoperative photos featured attendings (82.7%) performing …

Repeat Cytoreduction And Hyperthermic Intraperitoneal Chemotherapy For Recurrent Mucinous Appendiceal Adenocarcinoma: A Viable Treatment Strategy With Demonstrable Benefit, Neal Bhutiani, Travis E Grotz, Seth J Concors, Michael G White, Beth A Helmink, Kanwal P Raghav, Melissa W Taggart, Karen A Beaty, Richard E Royal, Michael J Overman, Aurelio Matamoros, Christopher P Scally, Safia Rafeeq, Paul F Mansfield, Keith F Fournier

Faculty, Staff and Student Publications

INTRODUCTION: Many patients with mucinous appendiceal adenocarcinoma experience peritoneal recurrence despite complete cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Prior work has demonstrated that repeat CRS/HIPEC can prolong survival in select patients. We sought to validate these findings using outcomes from a high-volume center.

PATIENTS AND METHODS: Patients with mucinous appendiceal adenocarcinoma who underwent CRS/HIPEC at MD Anderson Cancer Center between 2004 and 2021 were stratified by whether they underwent CRS/HIPEC for recurrent disease or as part of initial treatment. Only patients who underwent complete CRS/HIPEC were included. Initial and recurrent groups were compared.

RESULTS: Of 437 CRS/HIPECs performed …