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Ketamine As A Treatment Modality For Treatment-Resistant Depression, Tracy Wulff, Shen Cao
Ketamine As A Treatment Modality For Treatment-Resistant Depression, Tracy Wulff, Shen Cao
Physician Assistant Capstones, 2020-current
Many recent studies have demonstrated the ability of ketamine, an NMDA receptor antagonist, to produce antidepressant effects that may be effective in helping reduce treatment-resistant major depression. In particular, three double-blinded randomized control trials have been conducted to assess the viability and effectiveness of this medication for treatment. This systematic literature review will analyze these studies and determine if the overall research indicates that ketamine is useful in improving depression as measured by the Montgomery–Asberg Depression Rating Scale (MADRS)1.
Objective: Assess the effectiveness of IV Ketamine in reducing treatment-resistant major depressive disorder as measured by the Montgomery–Asberg …