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Articles 31 - 31 of 31
Full-Text Articles in Pathology
Nalidixic Acid Screening Test In Detection Of Decreased Fluoroquinolone Susceptibility In Salmonella Typhi Isolated From Blood, Afia Zafar, Ng Ibrahim, T Ahsan, Z Abbas, A Zaidi, Rumina Hasan
Nalidixic Acid Screening Test In Detection Of Decreased Fluoroquinolone Susceptibility In Salmonella Typhi Isolated From Blood, Afia Zafar, Ng Ibrahim, T Ahsan, Z Abbas, A Zaidi, Rumina Hasan
Department of Pathology and Laboratory Medicine
OBJECTIVE: To determine the validity of nalidixic acid screening test in the detection of high MICs of fluoroquinolone against Salmonella(S.) typhi isolated from blood and correlate zone diameters of ofloxacin with that of MIC value for nalidixic acid sensitive and resistant strains.
DESIGN: Cross-sectional analytical study.
PLACE AND DURATION OF STUDY: Clinical Microbiology Laboratory of the Aga Khan Hospital, Karachi from January 2002 to December 2003.
METHODS: Two hundred S. typhi isolates from blood were included for nalidixic acid screening and ofloxacin susceptibility. Antibiotic susceptibilities for both the antibiotics were obtained by disc diffusion method whereas MICs were determined …