Emergency Medicine Commons^™

Emergency Medicine Resident On Shift Clinical Teaching Efficacy As Measured By Student Evaluation And Self-Reflection Using A Previously Validated Metric, Alan R. Cherney Md, Dawn M. Yenser, Amy B. Smith Phd, Kevin Weaver D.O.,Facoep, Charles C. Worrilow Md, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Telemedicine Resuscitation And Arrest Trial (Treat): A Feasibility Study Of Real-Time Provider-To-Provider Telemedicine For The Care Of Critically Ill Patients, Anish K. Agarwal, David F. Gaieski, Sarah M. Perman, Marion Leary, Gail Delfin, Benjamin S. Abella, Brendan G. Carr

Department of Emergency Medicine Faculty Papers

No abstract provided.

Epigenetic Repression Of Pdz-Lim Domain-Containing Protein 2 Promotes Ovarian Cancer Via Nos2-Derived Nitric Oxide Signaling., Linjie Zhao, Chuan Yu, Shengtao Zhou, Wayne Bond Lau, Bonnie Lau, Zhongyue Luo, Qiao Lin, Huiliang Yang, Yu Xuan, Tao Yi, Xia Zhao, Yuquan Wei

Department of Emergency Medicine Faculty Papers

Ovarian cancer constitutes one of the most lethal gynaecological malignancies worldwide and currently no satisfactory therapeutic approaches have been established. Therefore, elucidation of molecular mechanisms to develop targeted therapy of ovarian cancer is crucial. PDLIM2 is critical to promote ubiquitination of nuclear p65 and thus its role in inflammation has been highlighted recently. We demonstrate that PDLIM2 is decreased in both ovarian high-grade serous carcinoma and in various human ovarian cancer cell lines compared with normal ovary tissues and human ovarian surface epithelial cells (HOSE). Further functional analysis revealed that PDLIM2 is epigenetically repressed in ovarian cancer development and inhibition …

Cola With A Splash Of Arsenic: Acute Arsenic Poisoning, Ryan Rogers Do, Jennifer Strow Do, Philip Dunn Do, Robert D. Cannon Do, Jeffrey P. Reboul Do

Department of Emergency Medicine

No abstract provided.

Gender Differences In Study Enrollment For A Mechanical Fall Prevention Study, Kaley J. Miller Bs, Pa-S, Bryan G. Kane Md, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Vartika Bhardwaj Ms, Michael Goodwin Ms, Cameron Paterson Ms, Kara Mia V. Villaneuva Msii, Phillip Zegelbone Ms, Bernadette Glenn-Porter Bs, Marna R. Greenberg Do, Mph, Facep, Samantha L. Myles Bs

Department of Emergency Medicine

No abstract provided.

Medical School Partnerships: Addressing Rough Sleeping In Vulnerable Youth., Rachael Snow Ms4, Sen Lu Ms4, Rachel Fieman Ms4, Jameson Dyal Ms4, Phillip Zegelbone Ms4, Brett Feldman Pa-C, Amy E. Smith Phd, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.

Pentobarbital Toxicity After Self-Administration Of Euthasoltm Veterinary Euthanasia Medication, Steven J. Crellin Do, Kenneth D. Katz Md

Department of Emergency Medicine

No abstract provided.

Serotonin Syndrome Associated With Therapeutic Metaxalone Dosing In A Patient With Cirrhosis, Ryan M Surmaitis Do, Thomas M. Nappe Do, Matthew D. Cook Do

Department of Emergency Medicine

No abstract provided.

A Case Of Three Patients With Severe Hypothermia Rewarmed With Ecmo, Matthew Niehaus Do, Rita Pechulis Md, Fccp, James K. Wu Md

Department of Emergency Medicine

No abstract provided.

Concomitant Retrograde Coronary Venous Infusion Of Basic Fibroblast Growth Factor Enhances Engraftment And Differentiation Of Bone Marrow Mesenchymal Stem Cells For Cardiac Repair After Myocardial Infarction., Xiao Wang, Lei Zhen, Huangtai Miao, Qiwei Sun, Ya Yang, Bin Que, Edmundo Patricio Lopes Lao, Xingxin Wu, Hongmei Ren, Shutian Shi, Wayne Bond Lau, Xin-Liang Ma, Changsheng Ma, Shaoping Nie

Department of Emergency Medicine Faculty Papers

AIM: Basic fibroblast growth factor (bFGF) increases the migration and viability of bone marrow mesenchymal stem cells (MSCs) in vitro. Retrograde coronary venous infusion can provide both increased regional bFGF concentrations and homogeneous cell dissemination. We determined whether retrograde delivery of bFGF enhances the potency of transplanted MSCs for cardiac repair in a canine infarct model.

METHODS AND RESULTS: Under hypoxic conditions, cellular migration was significantly increased in MSCs co-cultured with bFGF compared to vascular endothelial growth factor or insulin-like growth factor, and bFGF promoted MSCs differentiation into a cardiomyocyte phenotype. A canine infarct model was employed by coronary ligation. …

Continued Confusion After Resolution Of Diabetic Ketoacidosis, Ryan Rogers Do, Gretchen A. Perilli Md, Philip Dunn Do

Department of Emergency Medicine

No abstract provided.

The Correlation Between Usmle And Comlex Exam Scores For Applicants To A Dually- Approved Emergency Medicine Residency: An Eight-Year Experience, Kathleen E. Kane Md, Dawn M. Yenser Pgme, Laura Semler Ms, Kevin Weaver Do, Gavin Barr Jr. Md, Terrence E. Goyke Do, Andre Burckhart Do, Adam Leonetti Do, Isamu Yoshioka, Bryan Kane Md

Department of Emergency Medicine

No abstract provided.

Subdural Hematoma As A Consequence Of Epidural Anesthesia., Tracy M Bishop Do, Kareem S. Elsayed Ms, Kathleen E. Kane Md

Department of Emergency Medicine

Regional spinal and epidural anesthesia are used commonly in operative procedures. While the most frequent complication, postdural puncture headache (PDPH), is a clinically diagnosed positional headache that is usually self-limited, subdural hemorrhage (SDH) is a potentially fatal complication that cannot be missed. We report a case of an otherwise healthy female who presented with persistent positional headache and was ultimately found to have a large subdural hematoma with midline shift requiring surgical evacuation.

Pediatric Emergency Medical Care In Yerevan, Armenia: A Knowledge And Attitudes Survey Of Out-Of-Hospital Emergency Physicians., Aline A. Baghdassarian, Ross I. Donaldson, Andrew D Depiero, Nancy L Chernett, Harsh P. Sule Md

Department of Emergency Medicine Faculty Papers

BACKGROUND: Out-of-hospital emergency care is at an early stage of development in Armenia, with the current emergency medical services (EMS) system having emergency physicians (EPs) work on ambulances along with nurses. While efforts are underway by the Ministry of Health and other organizations to reform the EMS system, little data exists on the status of pediatric emergency care (PEC) in the country. We designed this study to evaluate the knowledge and attitudes of out-of-hospital emergency physicians in pediatric rapid assessment and resuscitation, and identify areas for PEC improvement.

METHODS: We distributed an anonymous, self-administered Knowledge and Attitudes survey to a …

A Cross Sectional Study Of Medical Student Knowledge Of Evidence Based Medicine As Measured By The Fresno Test Of Evidence Based Medicine, Lauren Semler Ms, Elizabeth Rehman, Zachary Haddad Bs, Katie Ahmadzadeh Do, Steven J. Crellin Do, Katarzyna Falkowska Do, Kalif Kendig Do, Brent H. Steinweg Do, Amy B. Smith Phd, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Comparison Of Airway Intubation Devices When Using A Biohazard Suit: A Feasibility Study, Kevin Weaver Do, Kayla R. Long Do, Gavin C. Barr Jr. Md, Jeffery P. Reboul Do, Aaron S. Ratner Do, Leonel Diaz Jr.,Do, Dougals A. Sturm Do, Bernadette Glenn-Porter Bs, Marna R. Greenberg Do, Mph, Facep, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Curcumin-Induced Heme Oxygenase-1 Expression Prevents H2o2-Induced Cell Death In Wild Type And Heme Oxygenase-2 Knockout Adipose-Derived Mesenchymal Stem Cells., Niels A J Cremers, Ditte M S Lundvig, Stephanie C M Van Dalen, Rik F Schelbergen, Peter L E M Van Lent, Walter A Szarek, Raymond F. Regan, Carine E Carels, Frank A D T G Wagener

Department of Emergency Medicine Faculty Papers

Mesenchymal stem cell (MSC) administration is a promising adjuvant therapy to treat tissue injury. However, MSC survival after administration is often hampered by oxidative stress at the site of injury. Heme oxygenase (HO) generates the cytoprotective effector molecules biliverdin/bilirubin, carbon monoxide (CO) and iron/ferritin by breaking down heme. Since HO-activity mediates anti-apoptotic, anti-inflammatory, and anti-oxidative effects, we hypothesized that modulation of the HO-system affects MSC survival. Adipose-derived MSCs (ASCs) from wild type (WT) and HO-2 knockout (KO) mice were isolated and characterized with respect to ASC marker expression. In order to analyze potential modulatory effects of the HO-system on ASC …

Troponin Leak Associated With Drug-Induced Methemoglobinemia., Robert D. Cannon Do, Michael Wagner, Jeanne L. Jacoby Md

Department of Emergency Medicine

Drug-induced methemoglobinemia is a well-described entity but has not been previously associated with elevated troponins in the absence of cardiac symptoms. We report a case of a patient presenting to the emergency department (ED) with complaints related to an exacerbation of her long-standing cystitis. A low pulse oximetry reading prompted an evaluation, revealing a troponin leak, which peaked at 10 hours. Her methemoglobin level was found to be elevated at 11.4%, but a preexisting anemia apparently prevented the clinical recognition of cyanosis. The methemoglobinemia was determined to be secondary to her ingestion of phenazopyridine and trimethoprim-sulfa methoxizole. Although phenazopyridine and …

Neuroprotective Effect Of Heme Oxygenase-2 Knockout In The Blood Injection Model Of Intracerebral Hemorrhage., Jing Chen-Roetling, Ying Cai, Raymond F Regan

Department of Emergency Medicine Faculty Papers

BACKGROUND: The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vitro and reduces oxidative stress after striatal blood injection. In order to further evaluate HO-2 as a therapeutic target, we tested the hypothesis that HO-2 gene deletion protects neurons and attenuates behavioral deficits after ICH.

FINDINGS: Injection of 20 μl blood into the right striatum of HO-2 wild-type mice resulted in loss of approximately one third of striatal neurons …

Understanding Non-Emergent Pediatric Ed Visits: Using Hospital And Family Centric Data To Inform System Redesign, Deborah Swavely Dnp, Rn, Kathy Baker Mph, Rn, Krista L. Bilger Bsn, Rn, David Zimmerman Mph, Andrew Martin Msn, Rn

Department of Community Health and Health Studies

No abstract provided.

Gender Differences In Cardiac Arrest Survivors Who Receive Therapeutic Hypothermia (Poster), Marna R. Greenberg Do, Mph, Facep, Amy M. Ahnert Md, Nainesh C. Patel Md, Courtney Bennett Do, Nicole Elliott Do, Mark Lundquist, Andrew C. Miller Do, Ellina C. Feiner Md, Anita Kurt Phd, Rn, Bernadette Gl-Porter Bs, Mercedes Rios-Scott Bs, David B. Burmeister Do, Facep

Department of Emergency Medicine

No abstract provided.

The Effect Of Triage-Based Application Of The Ottawa Ankle And Foot Rules (Oar/Ofr) On The Number Of Radiographs Ordered: A Pilot Study, John V. Ashurst Do, Stephanie Digiambattista Md, Thomas M. Nappe Do, Avinash Kambhampati Do, Sarfraz Alam, Michele Ortiz Rn, Paul Delpais Bsn, Rn, Cen, Bernadette Gl-Porter Bs, Anita Kurt Phd, Rn, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.

Perceived Mechanical Fall Risk And Openness To Communication With Providers, Marna R. Greenberg Do, Mph, Facep, Michael Nguyen Md, Brian Stello Md, Robert D. Barraco Md, Arnold R. Goldberg Md, Colin L. Donnelly Do, Benjamin R. Preiss Do, Bernadette Gl-Porter Bs, Anita Kurt Phd, Rn, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Palliative Medicine Competency Education In Emergency Medicine Residency Training: A Preliminary Report, Chadd K. Kraus Do, Mph, Matthew Meyers Bs, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.

A Statewide Survey Of Institutional Trauma Human Resource Allocation And Associated Patient Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do

Department of Emergency Medicine

No abstract provided.

Does Destination Determine Destiny? A Statewide Analysis Of Trauma Center Mortality, Bryan G. Kane Md, Quincy Gerrald Do, Catherine Fischer Do, Kevin Vong Do, Mary Sibley Do, Justin Binstead Do

Department of Emergency Medicine

No abstract provided.

Gender Differences In Perceptions And Self-Reported Driving Behaviors Among Teenagers. (Poster), Gavin C. Barr Jr. Md, Kathleen E. Kane Md, Robert D. Barraco Md, Timarie Rayburg Do, Lauren Dugan Do, Chadd K. Kraus Do, Mph, Marna R. Greenberg Do, Mph, Facep, Valerie Rupp Rn, Bsn, Kimberly Hamilton, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Introduction Of Evidence-Based Diagnostic Order Sets In An Electronic Medical Record Is Associated With An Increase In Laboratory Orders, Bryan G. Kane Md, Justin Arnold Do, Joshua Morrison Do, Ryan Southworth Do, William Greenhut Do, Will Russell Do, Jeremy Selley Do, Michael Stanley Do

Department of Emergency Medicine

No abstract provided.

Management Of Benign Paroxysmal Positional Vertigo: A Randomized Controlled Trial, Regina Sacco Dpt, Ba, Bhsc, David B. Burmeister Do, Facep, Valerie Rupp Rn, Bsn, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is a common presenting problem.

OBJECTIVE: Our aim was to compare the efficacy of vestibular rehabilitation (maneuver) vs. conventional therapy (medications) in patients presenting to the emergency department (ED) with BPPV.

METHODS: This was a prospective, single-blinded physician, randomized pilot study comparing two groups of patients who presented to the ED with a diagnosis of BPPV at a Level 1 trauma center with an annual census of approximately 75,000. The first group received standard medications and the second group received a canalith repositioning maneuver. The Dizziness Handicap Inventory was used to measure symptom resolution. …

Management Of Benign Paroxysmal Positional Vertigo: A Randomized Control Trial, Regina Sacco Dpt, Ba, Bhsc, David B. Burmeister Do, Facep, Valerie Rupp Rn, Bsn, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

Management of Benign Paroxysmal Positional Vertigo: A Randomized Control Trial

Regina R. Sacco, DPT, BA, BHSc, David B. Burmeister, DO, Valerie Rupp, RN, MSN, CRNP, Marna Rayl Greenberg, DO, MPH

Background: Benign Paroxysmal Positional Vertigo (BPPV) is a common complaint of patients who seek care in the Emergency Department (ED).

Objective: To compare the efficacy of vestibular rehabilitation (maneuver) vs. conventional therapy (medications) in ED patients with BPPV. In particular we sought to evaluate the improvement of vertigo in patients diagnosed with BPPV in the ED, assess their disposition time, and compare patient satisfaction between those patients who receive standard …