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Full-Text Articles in Emergency Medicine

Concurrent Primary Cardiac Tumors In A High Risk Patient Presenting With Tamponade, Joseph B. Zackary Md, Lauren Crowley Ba, Shawn M. Quinn Do, Timothy S. Misselbeck Oct 2020

Concurrent Primary Cardiac Tumors In A High Risk Patient Presenting With Tamponade, Joseph B. Zackary Md, Lauren Crowley Ba, Shawn M. Quinn Do, Timothy S. Misselbeck

Department of Emergency Medicine

No abstract provided.


The Impact Of Appendectomy In Clostridium Difficile Infection And Length Of Hospital Stay., Rajesh Essrani Md, Dany Saturno, Shehriyar Mehershahi, Rajesh Kumar Essrani, Muhammad Rajib Hossain, Shri Jai Kirshan Ravi, Andrea Berger, Asif Mehmood Sep 2020

The Impact Of Appendectomy In Clostridium Difficile Infection And Length Of Hospital Stay., Rajesh Essrani Md, Dany Saturno, Shehriyar Mehershahi, Rajesh Kumar Essrani, Muhammad Rajib Hossain, Shri Jai Kirshan Ravi, Andrea Berger, Asif Mehmood

Department of Emergency Medicine

Introduction We aim to investigate Clostridium difficile infection (CDI) recurrence, severity, complications, and length of hospital stay in patients with and without prior history of appendectomy who were admitted to the hospital with CDI. Method We analyzed retrospective data for 862 patients, 18 years and older, with C. difficile inpatients diagnosed between January 1, 2017 and December 31, 2018 and sorted into two groups, with or without prior appendicectomy, to look for outcomes such as recurrence, hospital stay, complications, and related death in each group and use statistical analysis for comparison. Result There were 862 patients admitted with CDI, of …


Physician Directed Smoking Cessation In The Ed: Do Patients Opt-Out?, Ali S. Aziz Bs, Natalie M. Greco Md, Timothy J. Batchelor Md, Andrew H F Miller Do, Theodore Doherty Do, Robert Kruklitis Md, Phd, Lauren Crowley Ba, Edward W. Casey Rph, Mba, Elizabeth A. Maclean Pharmd, Phd, Joann B. Trainer Pharmd, Marna R. Greenberg Do, Mph, Facep Apr 2020

Physician Directed Smoking Cessation In The Ed: Do Patients Opt-Out?, Ali S. Aziz Bs, Natalie M. Greco Md, Timothy J. Batchelor Md, Andrew H F Miller Do, Theodore Doherty Do, Robert Kruklitis Md, Phd, Lauren Crowley Ba, Edward W. Casey Rph, Mba, Elizabeth A. Maclean Pharmd, Phd, Joann B. Trainer Pharmd, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.


Second Degree Av Heart Block After Candlenut Ingestion, Andrew L. Koons Do, Lexis Laubach Bs, Alexandra Amaducci Do, Robert D. Cannon Do, Kenneth D. Katz Md, Ryan M. Surmaitis Do, Matthew D. Cook Do, Gillian A. Beauchamp Md Mar 2020

Second Degree Av Heart Block After Candlenut Ingestion, Andrew L. Koons Do, Lexis Laubach Bs, Alexandra Amaducci Do, Robert D. Cannon Do, Kenneth D. Katz Md, Ryan M. Surmaitis Do, Matthew D. Cook Do, Gillian A. Beauchamp Md

Department of Emergency Medicine

No abstract provided.


Self-Harm Poisonings Among Transgender Patients: Analysis Of Toxicology Investigator’S Consortium Registry, Marna R. Greenberg Do, Mph, Facep, Natalie E. Ebeling-Koning Do, Cody R. Mcwhirter Bs, Mikayla B. Hurwitz Bs, Lexis T. Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Andrew L. Koons, Matthew D. Cook Do, Kenneth D. Katz Md, Robert D. Cannon Do, Ryan M Surmaitis Do Mar 2020

Self-Harm Poisonings Among Transgender Patients: Analysis Of Toxicology Investigator’S Consortium Registry, Marna R. Greenberg Do, Mph, Facep, Natalie E. Ebeling-Koning Do, Cody R. Mcwhirter Bs, Mikayla B. Hurwitz Bs, Lexis T. Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Andrew L. Koons, Matthew D. Cook Do, Kenneth D. Katz Md, Robert D. Cannon Do, Ryan M Surmaitis Do

Department of Emergency Medicine

No abstract provided.


Agents Of Exposure In Transgender Patient Cases Managed By A Toxicologist: An Analysis Of The Toxicology Investigator’S Consortium (Toxic) Registry, Phillip M. Grenz Do, Mikayla B. Hurwitz Bs, Cody R. Mcwhirter Bs, Lexis Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Matthew D. Cook Do, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do, Ryan M Surmaitis Do Mar 2020

Agents Of Exposure In Transgender Patient Cases Managed By A Toxicologist: An Analysis Of The Toxicology Investigator’S Consortium (Toxic) Registry, Phillip M. Grenz Do, Mikayla B. Hurwitz Bs, Cody R. Mcwhirter Bs, Lexis Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Matthew D. Cook Do, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do, Ryan M Surmaitis Do

Department of Emergency Medicine

No abstract provided.


Qualitative Analysis Of Emergency Medicine Resident Logged Patient Safety Observations, Bryan G. Kane Md, Jon D. Raso Bs, David M. Richardson Md, Kevin Weaver D.O.,Facoep, John W. Daubert Do, Rafay A. Khan Do, Claire L. Paulson Do, Dawn M. Yenser Mar 2020

Qualitative Analysis Of Emergency Medicine Resident Logged Patient Safety Observations, Bryan G. Kane Md, Jon D. Raso Bs, David M. Richardson Md, Kevin Weaver D.O.,Facoep, John W. Daubert Do, Rafay A. Khan Do, Claire L. Paulson Do, Dawn M. Yenser

Department of Emergency Medicine

No abstract provided.


Using The Qsat To Generate Multi-Source Feedback On An In-Situ Pediatric Simulation Case, Michael C. Nguyen Md, Nicole Elliott Do, Matthew D. Cook Do, Diane Begany Md, Zachary Matuzsan Do, Louis Morolla Do, Suzanne S. Partington Msn, Rn, Ccrn, Jennifer E. Macfarlan Mph, Michael Jong Md, Bryan G. Kane Md Mar 2020

Using The Qsat To Generate Multi-Source Feedback On An In-Situ Pediatric Simulation Case, Michael C. Nguyen Md, Nicole Elliott Do, Matthew D. Cook Do, Diane Begany Md, Zachary Matuzsan Do, Louis Morolla Do, Suzanne S. Partington Msn, Rn, Ccrn, Jennifer E. Macfarlan Mph, Michael Jong Md, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.


Sex-Specific Outcomes In A Substance Use Intervention Program., Alexandra Amaducci, Marna R. Greenberg Do, Mph, Facep, Andrew W. Sheen Do, Hanna R. Warren Do, Pratik M. Parikh Do, Paige Roth Lsw, Kevin Weaver D.O.,Facoep, David M. Richardson Md, David B. Burmeister Do, Facep, Cpe, Jennifer Stephens Do, Robert D. Cannon Do Mar 2020

Sex-Specific Outcomes In A Substance Use Intervention Program., Alexandra Amaducci, Marna R. Greenberg Do, Mph, Facep, Andrew W. Sheen Do, Hanna R. Warren Do, Pratik M. Parikh Do, Paige Roth Lsw, Kevin Weaver D.O.,Facoep, David M. Richardson Md, David B. Burmeister Do, Facep, Cpe, Jennifer Stephens Do, Robert D. Cannon Do

Department of Emergency Medicine

PURPOSE: We performed an emergency department (ED)-based substance use screening, motivational interview-based intervention, and treatment referral program with the goal of determining sex-specific outcomes. Specifically, in this quality improvement project, we aimed to determine whether there was a difference among sexes in the type of substances used; the frequency of positive screening results for substance use disorder; agreeing to an intervention; the type of follow-up evaluation, participation, and referral; and attempts to change substance use after intervention.

METHODS: We prospectively studied a convenience sample of patients at 3 hospitals in Northeastern Pennsylvania from May 2017 through February 2018. Inclusion criteria …


Characterizing Non-Heroin Opioid Overdoses Using Electronic Health Records., Amelia J Averitt, B. H. Slovis, Abdul A Tariq, David K Vawdrey, Adler J Perotte Nov 2019

Characterizing Non-Heroin Opioid Overdoses Using Electronic Health Records., Amelia J Averitt, B. H. Slovis, Abdul A Tariq, David K Vawdrey, Adler J Perotte

Department of Emergency Medicine Faculty Papers

Introduction: The opioid epidemic is a modern public health emergency. Common interventions to alleviate the opioid epidemic aim to discourage excessive prescription of opioids. However, these methods often take place over large municipal areas (state-level) and may fail to address the diversity that exists within each opioid case (individual-level). An intervention to combat the opioid epidemic that takes place at the individual-level would be preferable.

Methods: This research leverages computational tools and methods to characterize the opioid epidemic at the individual-level using the electronic health record data from a large, academic medical center. To better understand the …


Overcoming Brick And Mortar: Feasibility Of Implementation Of A Mat And Linkage To Treatment Program By Leveraging Community Partnerships, Gillian A. Beauchamp Md, Priyanka Lauber Do, Jamie Allen Do, Nathan Boateng Ba, Samantha A. Shaak Phd, Paige Roth Msw, Lsw, Crs, Lexis Laubach Bs, Lauren M. Crowley Ba, David B. Burmeister Do, Facep, Cpe, Marna R. Greenberg Do, Mph, Facep Oct 2019

Overcoming Brick And Mortar: Feasibility Of Implementation Of A Mat And Linkage To Treatment Program By Leveraging Community Partnerships, Gillian A. Beauchamp Md, Priyanka Lauber Do, Jamie Allen Do, Nathan Boateng Ba, Samantha A. Shaak Phd, Paige Roth Msw, Lsw, Crs, Lexis Laubach Bs, Lauren M. Crowley Ba, David B. Burmeister Do, Facep, Cpe, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.


A Paramedic Staffed Prehospital Program May Reduce Hospital Readmissions For Heart Failure, Bruce Feldman Do, Christopher J. Greb Nrp, Orlando E. Rivera Rn, Mahek Shah Md, Jennifer Nesfeder, Deborah W. Sundlof Do, Nael Hawwa Md, Alma N. Ohl Crnp, Tara K. Henry-Morrow Emt-P, Jeanne L. Jacoby Md Oct 2019

A Paramedic Staffed Prehospital Program May Reduce Hospital Readmissions For Heart Failure, Bruce Feldman Do, Christopher J. Greb Nrp, Orlando E. Rivera Rn, Mahek Shah Md, Jennifer Nesfeder, Deborah W. Sundlof Do, Nael Hawwa Md, Alma N. Ohl Crnp, Tara K. Henry-Morrow Emt-P, Jeanne L. Jacoby Md

Department of Emergency Medicine

No abstract provided.


Police Use Of Naloxone After Statewide Legislation Enabling First-Responder Administration, John F. Mccarthy Do, Kathryn A. Henry Do, Lauren Crowley Ba, David M. Sassa Aas, Kira D. Weaver Do, Robert D. Cannon Do, Tara K. Henry-Morrow Emt-P, Jennifer E. Macfarlan Mph, Jeanne L. Jacoby Md Oct 2019

Police Use Of Naloxone After Statewide Legislation Enabling First-Responder Administration, John F. Mccarthy Do, Kathryn A. Henry Do, Lauren Crowley Ba, David M. Sassa Aas, Kira D. Weaver Do, Robert D. Cannon Do, Tara K. Henry-Morrow Emt-P, Jennifer E. Macfarlan Mph, Jeanne L. Jacoby Md

Department of Emergency Medicine

No abstract provided.


Hour Prediction Rule - Letter To The Editor., Andrew L. Koons Do, Robert D. Cannon Do, Facmt, Gillian A. Beauchamp Md, Kenneth D. Katz Md, Matthew D. Cook Do, Ryan M. Surmaitis Do Oct 2019

Hour Prediction Rule - Letter To The Editor., Andrew L. Koons Do, Robert D. Cannon Do, Facmt, Gillian A. Beauchamp Md, Kenneth D. Katz Md, Matthew D. Cook Do, Ryan M. Surmaitis Do

Department of Emergency Medicine

In a recent issue of Academic Emergency Medicine, we read with interest the article titled: Hospital Observation Upon Reversal (HOUR) with Naloxone: A Prospective Clinical Prediction Rule Validation Study by Clemency et al. In order to avoid over-reliance on this decision rule and possible untoward effects of early discharge, we feel that there are some key points worth considering in this regard. It is important to note that the average dose of prehospital naloxone was 3.1mg, which was administered intranasally (IN) in 85% of the patients. This fact was briefly discussed in the paper in terms of area under the …


Feasibility Of Implementation Of An Emergency Department Discharge Opioid Taper Protocol, Gillian A. Beauchamp Md, Joshua Rosentel Bsn, Rn, Erin Farber Do, Joseph Levi Do, Dpt, Lexis Laubach Bs, Lauren Crowley Ba, Richard S. Mackenzie Md, Mboe, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep Oct 2019

Feasibility Of Implementation Of An Emergency Department Discharge Opioid Taper Protocol, Gillian A. Beauchamp Md, Joshua Rosentel Bsn, Rn, Erin Farber Do, Joseph Levi Do, Dpt, Lexis Laubach Bs, Lauren Crowley Ba, Richard S. Mackenzie Md, Mboe, David M. Richardson Md, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

No abstract provided.


Do Female Residents Actually Demonstrate Better Levels Of Empathy, Emotional Intelligence And Burnout Than Their Male Counterparts?, Jeanne L. Jacoby Md, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Barraco Md, Mph, Elaine A. Donoghue Md, Kevin Weaver D.O.,Facoep, Jennifer E. Macfarlan Mph, Alexander M. Rosenau Do, Joann F. Quinn Phd, Amy B. Smith Phd Oct 2019

Do Female Residents Actually Demonstrate Better Levels Of Empathy, Emotional Intelligence And Burnout Than Their Male Counterparts?, Jeanne L. Jacoby Md, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep, Robert D. Barraco Md, Mph, Elaine A. Donoghue Md, Kevin Weaver D.O.,Facoep, Jennifer E. Macfarlan Mph, Alexander M. Rosenau Do, Joann F. Quinn Phd, Amy B. Smith Phd

Department of Emergency Medicine

No abstract provided.


Acute Fondaparinux (Arixtra) Intentional Overdose Via Self-Injection: A Case Report, Andrew L. Koons Do, Kenneth D. Katz Md, Matthew D. Cook Do, Robert D. Cannon Do, Gillian A. Beauchamp Md, Ryan M. Surmaitis Do Apr 2019

Acute Fondaparinux (Arixtra) Intentional Overdose Via Self-Injection: A Case Report, Andrew L. Koons Do, Kenneth D. Katz Md, Matthew D. Cook Do, Robert D. Cannon Do, Gillian A. Beauchamp Md, Ryan M. Surmaitis Do

Department of Emergency Medicine

No abstract provided.


Beware Of Barbiturates: Coma And Hypothermia In A 94-Year-Old Woman Due To Combined Secobarbital And Pentobarbital Toxicity, Andrew L. Koons Do, Amy Wier Do, Kenneth D. Katz Md, Matthew D. Cook Do, Robert D. Cannon Do, Gillian A. Beauchamp Md, Ryan M. Surmaitis Do Apr 2019

Beware Of Barbiturates: Coma And Hypothermia In A 94-Year-Old Woman Due To Combined Secobarbital And Pentobarbital Toxicity, Andrew L. Koons Do, Amy Wier Do, Kenneth D. Katz Md, Matthew D. Cook Do, Robert D. Cannon Do, Gillian A. Beauchamp Md, Ryan M. Surmaitis Do

Department of Emergency Medicine

No abstract provided.


The Anticipated Negative Impact On Emergency Medicine Faculty Of The New Acgme Common Program Requirements (Poster)., Shawn M. Quinn Do, Bryan G. Kane Md, Terrence E. Goyke, Dawn M. Yenser C-Tagme, Marna R. Greenberg Do, Mph, Facep, Gavin C. Barr Jr. Md Apr 2019

The Anticipated Negative Impact On Emergency Medicine Faculty Of The New Acgme Common Program Requirements (Poster)., Shawn M. Quinn Do, Bryan G. Kane Md, Terrence E. Goyke, Dawn M. Yenser C-Tagme, Marna R. Greenberg Do, Mph, Facep, Gavin C. Barr Jr. Md

Department of Emergency Medicine

No abstract provided.


Feasibility Of Incorporating Components Of A ‘Sex And Gender’ In Em Toolkit Into Residency Education, Alyson J. Mcgregor Md, Ma, Marna R. Greenberg Do, Mph, Facep, Rebecca Barron Md, Mph, Lauren A. Walter Md, Jeannette Wolfe Md, Ashley L. Deutsch Md, Steven A. Johnson Md, Derek A. Robinett Md, Gillian A. Beauchamp Md Apr 2019

Feasibility Of Incorporating Components Of A ‘Sex And Gender’ In Em Toolkit Into Residency Education, Alyson J. Mcgregor Md, Ma, Marna R. Greenberg Do, Mph, Facep, Rebecca Barron Md, Mph, Lauren A. Walter Md, Jeannette Wolfe Md, Ashley L. Deutsch Md, Steven A. Johnson Md, Derek A. Robinett Md, Gillian A. Beauchamp Md

Department of Emergency Medicine

No abstract provided.


Hallway Bed Status Is Associated With Lower Patient Satisfaction, Max Needham Ba, Kathryn B. Bartlett Do, Akshay Gupta Do, John J. Scholz Do, Jennifer Sadowski Do, Bryan G. Kane Md, Jeanne L. Jacoby Md, Marna R. Greenberg Do, Mph, Facep, David M. Richardson Md Apr 2019

Hallway Bed Status Is Associated With Lower Patient Satisfaction, Max Needham Ba, Kathryn B. Bartlett Do, Akshay Gupta Do, John J. Scholz Do, Jennifer Sadowski Do, Bryan G. Kane Md, Jeanne L. Jacoby Md, Marna R. Greenberg Do, Mph, Facep, David M. Richardson Md

Department of Emergency Medicine

No abstract provided.


Status Of Sex And Gender In Emergency Medicine A Five Year Follow Up Report, Basmah Safdar Md, Msc, Kimberly E. Ona Ayala Ba, Syed Shayan Ali Md, Benjamin J. Seifer Bsme, Michelle Hong Bs, Ms, Marna R. Greenberg Do, Mph, Facep, Esther K. Choo Md, Mph, Alyson J. Mcgregor Md, Ma Apr 2019

Status Of Sex And Gender In Emergency Medicine A Five Year Follow Up Report, Basmah Safdar Md, Msc, Kimberly E. Ona Ayala Ba, Syed Shayan Ali Md, Benjamin J. Seifer Bsme, Michelle Hong Bs, Ms, Marna R. Greenberg Do, Mph, Facep, Esther K. Choo Md, Mph, Alyson J. Mcgregor Md, Ma

Department of Emergency Medicine

No abstract provided.


A Case Of Creutzfeldt-Jakob Disease Presenting With Depression And Anxiety, Kathryn B. Bartlett Do, Kathleen E. Kane Md, Bryan G. Kane Md, Kevin Weaver D.O.,Facoep, Gavin C. Barr Jr. Md Apr 2019

A Case Of Creutzfeldt-Jakob Disease Presenting With Depression And Anxiety, Kathryn B. Bartlett Do, Kathleen E. Kane Md, Bryan G. Kane Md, Kevin Weaver D.O.,Facoep, Gavin C. Barr Jr. Md

Department of Emergency Medicine

No abstract provided.


Sex Specific Outcomes Of An Ed Stopping Elderly Accidents, Deaths, And Injuries (Ed-Steadi) Program, Marna R. Greenberg Do, Mph, Facep, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Victoria Goodheart Do, Alexander Youngdahl Do, Ryan Day Md, Danielle Collins Md, Lauren Crowley Ba, Bryan G. Kane Md Apr 2019

Sex Specific Outcomes Of An Ed Stopping Elderly Accidents, Deaths, And Injuries (Ed-Steadi) Program, Marna R. Greenberg Do, Mph, Facep, Jeanne L. Jacoby Md, Robert D. Barraco Md, Mph, Victoria Goodheart Do, Alexander Youngdahl Do, Ryan Day Md, Danielle Collins Md, Lauren Crowley Ba, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.


Using The Qsat To Generate Multi-Source Feedback On An In-Situ Pediatric Simulation Case, Michael C. Nguyen Md, Nicole Elliott Do, Michael R. Jong Md, Msc, Suzanne S. Puentes Bsn, Ccrn, Rn, Diane Begany Md, Matthew D. Cook Do, Louis Morolla Do, Zachary Matuzsan Do, Jennifer E. Macfarlan Mph, Bryan G. Kane Md Mar 2019

Using The Qsat To Generate Multi-Source Feedback On An In-Situ Pediatric Simulation Case, Michael C. Nguyen Md, Nicole Elliott Do, Michael R. Jong Md, Msc, Suzanne S. Puentes Bsn, Ccrn, Rn, Diane Begany Md, Matthew D. Cook Do, Louis Morolla Do, Zachary Matuzsan Do, Jennifer E. Macfarlan Mph, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.


Opinions Of Academic Em Society Members On The New Acgme Common Program Requirements, Shawn M. Quinn Do, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep, Terrence E. Goyke, Steven Bird Md, Megan Schagrin Mba, Gavin C. Barr Jr. Md Mar 2019

Opinions Of Academic Em Society Members On The New Acgme Common Program Requirements, Shawn M. Quinn Do, Bryan G. Kane Md, Marna R. Greenberg Do, Mph, Facep, Terrence E. Goyke, Steven Bird Md, Megan Schagrin Mba, Gavin C. Barr Jr. Md

Department of Emergency Medicine

No abstract provided.


Emergency Department Skull Trephination For Management Of Acute Epidural Hematoma, Julie A. Fritzges Do Mar 2019

Emergency Department Skull Trephination For Management Of Acute Epidural Hematoma, Julie A. Fritzges Do

Department of Emergency Medicine

No abstract provided.


Safety Oriented, Low-Cost Peritonsillar Abscess Needle Aspiration Model For Emergency Medicine Simulation, Anne Mai Bs, Julie A. Fritzges Do, Gavin C. Barr Jr. Md, Marna R. Greenberg Do, Mph, Facep, Smeet Bhimani Do Mar 2019

Safety Oriented, Low-Cost Peritonsillar Abscess Needle Aspiration Model For Emergency Medicine Simulation, Anne Mai Bs, Julie A. Fritzges Do, Gavin C. Barr Jr. Md, Marna R. Greenberg Do, Mph, Facep, Smeet Bhimani Do

Department of Emergency Medicine

No abstract provided.


A Case Report Of Massive Acetaminophen Poisoning Treated With A Novel “Triple Therapy”: N-Acetylcysteine, 4-Methylpyrazole, And Hemodialysis, Emily A. Kiernan Do, Julie A. Fritzges Do, Kathryn Henry Do, Kenneth D. Katz Md Mar 2019

A Case Report Of Massive Acetaminophen Poisoning Treated With A Novel “Triple Therapy”: N-Acetylcysteine, 4-Methylpyrazole, And Hemodialysis, Emily A. Kiernan Do, Julie A. Fritzges Do, Kathryn Henry Do, Kenneth D. Katz Md

Department of Emergency Medicine

Massive acetaminophen (N-acetyl-p-aminophenol; APAP) ingestion is characterized by a rapid onset of mitochondrial dysfunction, including metabolic acidosis, lactemia, and altered mental status without hepatotoxicity which may not respond to the standard doses of N-acetylcysteine (NAC). A 64-year-old woman without medical history presented comatose after an ingestion of 208 tablets of Tylenol PM™ (APAP 500 mg and diphenhydramine 25 mg). The initial APAP concentration measured 1,017 µg/mL (therapeutic range 10-30 µg/mL), and elevated anion gap metabolic acidosis, lactemia, and 5-oxoprolinemia were detected. High-dose intravenous (IV) NAC, 4-methylpyrazole (4-MP), and hemodialysis (HD) were initiated. She was transferred to a liver …


Lamotrigine Odt-Induced Seizure In A 3-Year-Old Child After Accidental Ingestion, Ashley Griswold Do, Briana Tully, Kenneth D. Katz Md, Gillian A. Beauchamp Md, Matthew D. Cook Do, Robert D. Cannon Do Jan 2019

Lamotrigine Odt-Induced Seizure In A 3-Year-Old Child After Accidental Ingestion, Ashley Griswold Do, Briana Tully, Kenneth D. Katz Md, Gillian A. Beauchamp Md, Matthew D. Cook Do, Robert D. Cannon Do

Department of Emergency Medicine

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.