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Articles 151 - 151 of 151
Full-Text Articles in Critical Care
Testotoxicosis: Gonadotrophin-Independent Male Sexual Precocity, A A. Aziz, S M. Jafri, N U. Haque
Testotoxicosis: Gonadotrophin-Independent Male Sexual Precocity, A A. Aziz, S M. Jafri, N U. Haque
Section of Pulmonary & Critical Care
In this era of rapidly developing investigational tools and pharmacology, the pathophysiology of precocious puberty is becoming well defined. What was previously thought to be a form of gonadotrophin releasing hormone (GNRH)-dependent central precocious puberty is now classified as GNRH-independent familial testotoxicosis. We present two such cases and review the clinical features, pathophysiology and treatment of testotoxicosis.